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MSITKNAPREGAEEVAATALGVAAARAAETRRQRPLIVDPFAQLFVDAAGQDLWSMVASGAAHDELASAD PALAAVMQTSLGHIASRTKFFDEFVLAAADAGIRQVVSLGAGLDTRAWRLSWPDAVTVYELEQPNVLEFK LATLRDNGATPAANYVDVPVDLHRCWPRSLCLAGFDPAAPTAWLVEGLLPFLSVAAQDLLFGDVHKLSVP GSWLAAEALSSEFLKPTTVARQRARIRRMRVTAATLAGLSNVTELWDLAEGRSDVADWLRGRGWHASVLT AERLLARYHRSAPVELGDATPPSLYVTARLSAESSLDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1595 | - | - | 100% (318) | O-methyltransferase |
| M. marinum M | MMAR_5323 | - | 4e-78 | 50.33% (302) | O-methyltransferase |
| M. marinum M | MMAR_0955 | - | 5e-74 | 47.76% (312) | hypothetical protein MMAR_0955 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3793c | - | 1e-86 | 55.18% (299) | hypothetical protein Mb3793c |
| M. gilvum PYR-GCK | Mflv_0743 | - | 9e-58 | 40.88% (296) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv3767c | - | 1e-86 | 55.18% (299) | hypothetical protein Rv3767c |
| M. leprae Br4923 | MLBr_02640 | - | 2e-49 | 40.89% (291) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3886c | - | 2e-67 | 46.20% (303) | hypothetical protein MAB_3886c |
| M. avium 104 | MAV_0301 | - | 5e-82 | 51.27% (314) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_0093 | - | 1e-57 | 46.05% (304) | methyltransferase |
| M. thermoresistible (build 8) | TH_2759 | - | 4e-57 | 44.37% (302) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_4402 | - | 4e-79 | 50.66% (302) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 3e-61 | 42.30% (305) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3793c|M.bovis_AF2122/97 -----------MPRTDNDSWAITESVGATALGVAAARAAETESDNPLIND
Rv3767c|M.tuberculosis_H37Rv -----------MPRTDNDSWAITESVGATALGVAAARAAETESDNPLIND
MAV_0301|M.avium_104 -----------MPRTDNDSWDITQSVGATALGVAAARAAETESENPLISD
MUL_4402|M.ulcerans_Agy99 -----------MPRTDNDSWTITESVGATALGVAAARAAETESENPLIED
MMAR_1595|M.marinum_M -----------MSITKNAPREGAEEVAATALGVAAARAAETRRQRPLIVD
MAB_3886c|M.abscessus_ATCC_199 -----------MARRDGDSWEITESVGTTALGVASARDAETRSPNPLISD
Mflv_0743|M.gilvum_PYR-GCK ---------MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALIND
Mvan_0104|M.vanbaalenii_PYR-1 ---------MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDD
MLBr_02640|M.leprae_Br4923 ------------MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRD
MSMEG_0093|M.smegmatis_MC2_155 ---MTDVRETPSVRSARDSWGITESVGATALGVAAARAAETAQADPLIRD
TH_2759|M.thermoresistible__bu MVMMFDVTEAASARSEGDSWDITESVGATALGVAAERALETSQPDPLIRD
. .*.:**: **: * ** .** *
Mb3793c|M.bovis_AF2122/97 PFARIFVDAAGDGIWSMY-TNRTLLAGATDLDPDLRAPIQQMIDFMAART
Rv3767c|M.tuberculosis_H37Rv PFARIFVDAAGDGIWSMY-TNRTLLAGATDLDPDLRAPIQQMIDFMAART
MAV_0301|M.avium_104 PFARIFVDAAGKGMWSIY-ADPALLTKADDLEPDLRGRLQLMIDFMATRT
MUL_4402|M.ulcerans_Agy99 PFARVFVDAAGDGMWSMF-ANPALLAGAPEIESQVGARVRQMIDFMATRT
MMAR_1595|M.marinum_M PFAQLFVDAAGQDLWSMV-ASGAAHDELASADPALAAVMQTSLGHIASRT
MAB_3886c|M.abscessus_ATCC_199 PYAGHFLAAAGDGAWNAYRFDGEPPAALVEAEPRLVERIDAMRSYVACRT
Mflv_0743|M.gilvum_PYR-GCK PYAKVLVEGAGAGA-WRFIADEDLVAKASESDTEVGALFEHMKNYQAVRT
Mvan_0104|M.vanbaalenii_PYR-1 PYAKILVAGAGNGA-WQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRT
MLBr_02640|M.leprae_Br4923 PYAKLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRT
MSMEG_0093|M.smegmatis_MC2_155 EFAFLLVS--AAGPTWAQMAVSDPHWLGA--DADARRIHEISRNYQAVRT
TH_2759|M.thermoresistible__bu EYAFLLVS--AAGPPWTQLASSDLSWLGD--DETARRMHLMSRDYQAVRT
:* :: . . : .. * **
Mb3793c|M.bovis_AF2122/97 AFFDEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLE
Rv3767c|M.tuberculosis_H37Rv AFFDEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLE
MAV_0301|M.avium_104 AFFDEFFLAAADAGVRQVVILAAGLDARSWRLPWPDGTVVYELDQPKVLD
MUL_4402|M.ulcerans_Agy99 AFFDEFFLGAADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPRVLE
MMAR_1595|M.marinum_M KFFDEFVLAAADAGIRQVVSLGAGLDTRAWRLSWPDAVTVYELEQPNVLE
MAB_3886c|M.abscessus_ATCC_199 KFFDDFFGDASTSGIRQAVILASGLDARAWRLDWPRDAVLFELDLPRVLA
Mflv_0743|M.gilvum_PYR-GCK HFFDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLD
Mvan_0104|M.vanbaalenii_PYR-1 HFFDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLA
MLBr_02640|M.leprae_Br4923 NFFDTYFNNAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLA
MSMEG_0093|M.smegmatis_MC2_155 HYFDEYFSDVAHAGIRQVVILAAGLDSRAFRLDWPAGTTVFEIDQPKVLE
TH_2759|M.thermoresistible__bu HYFDRYFAAAARAGIRQIVLLAAGLDSRAYRLDWPAGTVVYELDQPRVLD
:** :. . *:** * *.:***:*::** ** ..::*:: * **
Mb3793c|M.bovis_AF2122/97 FKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGL
Rv3767c|M.tuberculosis_H37Rv FKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGL
MAV_0301|M.avium_104 FKSTTLREHGAQPKAELVNVPIDLRQDWPKALQEAGFDASRPAVWSAEGL
MUL_4402|M.ulcerans_Agy99 FKSATLRQHGARPTAQLMNIPIDLRQDWPAALLDSGFDASKPTAWSAEGL
MMAR_1595|M.marinum_M FKLATLRDNGATPAANYVDVPVDLHRCWPRSLCLAGFDPAAPTAWLVEGL
MAB_3886c|M.abscessus_ATCC_199 FKAETLDKQGATPRIRHVPVAVDLRDDWPAALRAGGFDVGRPAAWIAEGL
Mflv_0743|M.gilvum_PYR-GCK YKSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGL
Mvan_0104|M.vanbaalenii_PYR-1 YKSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGL
MLBr_02640|M.leprae_Br4923 YKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGL
MSMEG_0093|M.smegmatis_MC2_155 YKTATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQPTAWLAEGL
TH_2759|M.thermoresistible__bu FKNRTLQAHGAVAKADRRTVAVDLRDDWPAALRHAGFDSAAPTAWLAEGL
:* ** :*. . :. **: ** :* *** .* .***
Mb3793c|M.bovis_AF2122/97 VRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRR
Rv3767c|M.tuberculosis_H37Rv VRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRR
MAV_0301|M.avium_104 VRYLPAQAQDLLFERIDALSVPGSRLASNVPDSGFTDPDRLARQREDMRR
MUL_4402|M.ulcerans_Agy99 VRYLPARAQDLLFERIDTLSPAGSWLATNVPQGGFLDPDLVRRQHEEMQR
MMAR_1595|M.marinum_M LPFLSVAAQDLLFGDVHKLSVPGSWLAAEALSSEFLKPTTVARQRARIRR
MAB_3886c|M.abscessus_ATCC_199 LPYLPPAAQDLLFERIDTLSAPGSRIAVENFGEDFFNPETLARQRERGQA
Mflv_0743|M.gilvum_PYR-GCK LMYLPADAQDRLFAQITELSAPGSQVAAESMG---VHAPDRRERMRERFA
Mvan_0104|M.vanbaalenii_PYR-1 LMYLPADAQDRLFAQITELSAPGSRVAAESMG---IHAQDRRERMRERFA
MLBr_02640|M.leprae_Br4923 LMYLPATAQDGLFTEIGGLSAVGSRIAVETSP---LHGDEWREQMQLRFR
MSMEG_0093|M.smegmatis_MC2_155 LPYLPADAQDRLFELVGVNSAPGSRIAVEAFN---MSPERYTEERRAQRR
TH_2759|M.thermoresistible__bu LCYLPADAQDRLFERITALSAPGSWLAVEAFH---HDPQRATERRRAEWR
: :*. *** ** : * ** :* : ..
Mb3793c|M.bovis_AF2122/97 MRAAAAKLVETEISDVDDLWYAEQ-RTAVAEWLRERGWDVSTATLPELLA
Rv3767c|M.tuberculosis_H37Rv MRAAAAKLVETEISDVDDLWYAEQ-RTAVAEWLRERGWDVSTATLPELLA
MAV_0301|M.avium_104 MRAAAAKLVDAEITDFDDLWYPEE-RTPVDSWLRERGWDVSTATFAELMA
MUL_4402|M.ulcerans_Agy99 MRAAAGRLVEIQMPAVEDLWYAEE-RTPVADWLGEHGWRASATTSAELLT
MMAR_1595|M.marinum_M MRVTAATLAG--LSNVTELWDLAEGRSDVADWLRGRGWHASVLTAERLLA
MAB_3886c|M.abscessus_ATCC_199 FRRVAEEMQGQDIPDVADLWYLEE-RTDAGEFLAGRGWRVTSETAVALLG
Mflv_0743|M.gilvum_PYR-GCK SIASQID--IEP-MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMR
Mvan_0104|M.vanbaalenii_PYR-1 SITAQFD--VEP-MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMR
MLBr_02640|M.leprae_Br4923 RVSDALG--FEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMR
MSMEG_0093|M.smegmatis_MC2_155 ARGEQMRKQLDLDIDVDALMYTADDRADAAQWLSEHGWQVEAVPSADEMA
TH_2759|M.thermoresistible__bu DRTARMKAALDLNLDFEALTYDDPDRADAGEWLAAHGWHPDSVPGTEEMA
. * *: . .:* :** . :
Mb3793c|M.bovis_AF2122/97 RYGRS-IPHSGEDSIPPNLFVSAQRATS-----
Rv3767c|M.tuberculosis_H37Rv RYGRS-IPHSGEDSIPPNLFVSAQRATS-----
MAV_0301|M.avium_104 RYGRS-IPQGAQDSMPPTLYVSAQRRAG-----
MUL_4402|M.ulcerans_Agy99 RYGRP-VPDDAEGPVPPTLFVSAHRPAA-----
MMAR_1595|M.marinum_M RYHRS-APVELGDATPPSLYVTARLSAESSLDA
MAB_3886c|M.abscessus_ATCC_199 RHGRD-IPADLPDATPNSAFLFAQKAD------
Mflv_0743|M.gilvum_PYR-GCK RLDRY---VEVADS--DGQSFSTFTTGTKL---
Mvan_0104|M.vanbaalenii_PYR-1 RLHRL---VEIADG--DDQSFSTFTTAVKR---
MLBr_02640|M.leprae_Br4923 RVGRWGDGVPMAD---DKDAFAEFVTAHRL---
MSMEG_0093|M.smegmatis_MC2_155 RLGRPAAEADLAEFGMDGVLMRARLDGERL---
TH_2759|M.thermoresistible__bu RMGRP-VPADLLDVAVPSTLLRAHLNGASR---
* * .