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PRISRDGSGGDSVIVGYQRFGDHRVKSRRLDRRASFTAQSCAAQRAAETLQPPDRRLLDDPYSRYFIHSP LLRVCLIHPLAARAFIEVLKSVFGAAGHFFLVLRARYTDDVVEAAVNDGVDQLVLLGAGFDTTALRRVSN STVKIFEVDAPTTQADKRAVMERLRPVQSPNPIVWVPCDFEHDTLREKLLDSGFDPTRPSLVVWLGVTAY LTREALDATLADLASLCAPGSRLVFDYLDTDVVAGDSTSLRARLWTQAAARFGEPYLTGLTATGADALLA AHGFTCEAHLTTRELLQHYASADVGRSSVDGRAAITTAQRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2209c | - | - | 100% (322) | hypothetical protein MAB_2209c |
| M. abscessus ATCC 19977 | MAB_2253 | - | 2e-24 | 38.35% (206) | hypothetical protein MAB_2253 |
| M. abscessus ATCC 19977 | MAB_3082 | - | 1e-21 | 30.48% (269) | hypothetical protein MAB_3082 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2772 | - | 7e-23 | 31.46% (267) | hypothetical protein Mb2772 |
| M. gilvum PYR-GCK | Mflv_3997 | - | 4e-16 | 30.04% (253) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv2751 | - | 8e-23 | 31.46% (267) | hypothetical protein Rv2751 |
| M. leprae Br4923 | MLBr_02020 | - | 1e-15 | 29.93% (274) | hypothetical protein MLBr_02020 |
| M. marinum M | MMAR_1964 | - | 2e-21 | 31.09% (267) | O-methyltransferase |
| M. avium 104 | MAV_3642 | - | 1e-20 | 29.80% (255) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_3424 | - | 5e-28 | 42.44% (205) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_4502 | - | 2e-11 | 29.31% (232) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_3393 | - | 7e-21 | 31.09% (267) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2390 | - | 2e-25 | 33.46% (257) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2209c|M.abscessus_ATCC_199 MPRISRDGSGGDSVIVGYQRFGDHRVKSRRLDRRASFTAQSCAAQRAAET
MSMEG_3424|M.smegmatis_MC2_155 -------------------------MDNSGPSRTALATAYARACHQFADS
Mb2772|M.bovis_AF2122/97 -----------------------------MARNPAAQTAFGPMVLAAVEQ
Rv2751|M.tuberculosis_H37Rv -----------------------------MARNPAAQTAFGPMVLAAVEQ
MMAR_1964|M.marinum_M -----------------------------MTRNPAAQTAFGPMVLSAVEQ
MUL_3393|M.ulcerans_Agy99 -----------------------------MTRNPAAQTAFGPMVLSAVEQ
MAV_3642|M.avium_104 ------------------------------------------MVLAAVEQ
Mflv_3997|M.gilvum_PYR-GCK ----------------------------MTSRDAAAETAFGPMVLAAIEH
Mvan_2390|M.vanbaalenii_PYR-1 ----------------------------MTARDAAAQTAFGPMVLAAIEQ
MLBr_02020|M.leprae_Br4923 -------------MMAATPEFGSLRSDDDHWDIVSSVGYTALLVAGWRAL
TH_4502|M.thermoresistible__bu --------------------MSSLRTDDDTWDIATSVGSTAVMVAASRAA
MAB_2209c|M.abscessus_ATCC_199 LQPPDRRLLDDPYSRYFIHSPLLRVCLIHPLAARAFIEVLKSVFGAA---
MSMEG_3424|M.smegmatis_MC2_155 PP-----IFADPLAARLLG---VTEANLDDLSRHPAGHPATVARDRP---
Mb2772|M.bovis_AF2122/97 NEPPGRRLVDDDLADLFLPRPLRWLAGATRSAVLRRLLISASEWSGR---
Rv2751|M.tuberculosis_H37Rv NEPPGRRLVDDDLADLFLPRPLRWLAGATRSAVLRRLLISASEWSGR---
MMAR_1964|M.marinum_M NEPAEHRLVDDDLADLFLPRPLRWLVSATRPAGIRRLFIRWSEWSGS---
MUL_3393|M.ulcerans_Agy99 NEPAEHRLVDDDLADLFLPRPLRWLVSATRPAGIRRLFIRWSEWSGS---
MAV_3642|M.avium_104 NEPPGRRLVDDDFAELFLPAPLRWLVGATRFAPVRHLMIRGSEFTGP---
Mflv_3997|M.gilvum_PYR-GCK NEPPDRRLVDDDLAESFLPNRFRLLVRCARVAAVRRAVIAAADRSGP---
Mvan_2390|M.vanbaalenii_PYR-1 NEPPLQRLVHDDLAESFLPGRLRLLVRLTRVAALRRAAATVTDRSGP---
MLBr_02020|M.leprae_Br4923 HAVGPQPLVRDEYAKYFITASRDPYLMNLLANPGTSLNETAFPR------
TH_4502|M.thermoresistible__bu ETEREDALIRDPYAKVLVAGAGTGVWELILDDDFTAKIEAADPETAAIFD
:. * : ::
MAB_2209c|M.abscessus_ATCC_199 GHFF-LVLRARYTDDVVEAAVNDGVDQLVLLGAGFDTTALRRVSNSTVKI
MSMEG_3424|M.smegmatis_MC2_155 RRLF-FAARSRFADDVTARAVAAGVRQVVVLGAGLDTAAYR-NSHPDVHV
Mb2772|M.bovis_AF2122/97 GLWANLACRKRFIGDKLDEALGD-IDAVVILGAGLDTRAYRLTRRVRMPV
Rv2751|M.tuberculosis_H37Rv GLWANLACRKRFIGDKLDEALGD-IDAVVILGAGLDTRAYRLTRRVRMPV
MMAR_1964|M.marinum_M GLWVNLTCRKRFIGDKLGEALDD-IDAVAILGAGLDTRAYRLTRKVRIPI
MUL_3393|M.ulcerans_Agy99 GLWVNLTCRKRFIGDRLGEALDD-VDAVAILGAGLDTRAYRLTRKMRIPI
MAV_3642|M.avium_104 GLWANLACRKRFIADKLKESLDD-INAVVILGAGLDTRAYLLTRRVRIPV
Mflv_3997|M.gilvum_PYR-GCK GLWASIACRKRYIDERLSDPLND-TDAVVVLGAGLDTRSCRIARHSTMPV
Mvan_2390|M.vanbaalenii_PYR-1 GLWASIACRKRYIDERLSDPLND-TDAVVVLGAGLDTRACRIARHGDLPV
MLBr_02020|M.leprae_Br4923 ----LYGVQTRFFDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATV
TH_4502|M.thermoresistible__bu HMGNYQAVRTHFFDTYFARAAEAGIRQVVILASGLDSRAYRLPWPDGTVV
: :: . .::.:*:*: : :
MAB_2209c|M.abscessus_ATCC_199 FEVDAPTTQADKRAVMERLRPVQSPNPIVWVPCDFEHDTLREKLLDSGFD
MSMEG_3424|M.smegmatis_MC2_155 FEVDHPQTQAWKRERLAATG-IDIPATATLVPVDFETQTLASELESASFS
Mb2772|M.bovis_AF2122/97 FEVDLPVNIARKAKTVRRVL-GELPLSVRLVALDFEHDDLLTALAEHGYR
Rv2751|M.tuberculosis_H37Rv FEVDLPVNIARKAKTVRRVL-GELPLSVRLVALDFEHDDLLTALAEHGYR
MMAR_1964|M.marinum_M FEVDLPVNIARKAKTVRRVL-GELPLSVRLVALDFEHDDLLTALAEHGYL
MUL_3393|M.ulcerans_Agy99 FEVDLPVNIARKAKTVRRVL-GELPLSVRLVALDFEHDDLLTALAEHGYL
MAV_3642|M.avium_104 FEVDLPVNVARKFKTVRRVL-GELPLSVRLVALDLEHDDLLTALAEHGYR
Mflv_3997|M.gilvum_PYR-GCK FEVDQQINVDRKQAVLRRTL-GEVPSSVRLVGVDLERGQVMPALRAQGYD
Mvan_2390|M.vanbaalenii_PYR-1 FEVDRPVNVDRKAAVLHRVF-GAVPASVHLVPVDLEEDPLIPALESHGYR
MLBr_02020|M.leprae_Br4923 FEIDLPKVLEFKARVLAEQG-AIPNAGRSEVAADLRAD-WPRALKAAGFD
TH_4502|M.thermoresistible__bu YEIDQPKVLEYKSATLAAHG-VQPAADRREVAVDLRHD-WPKALRAKGFD
:*:* * : * *:. * .:
MAB_2209c|M.abscessus_ATCC_199 PTRPSLVVWLGVTAYLTREALDATLADLASLCAPGSRLVFDYLDTDVVAG
MSMEG_3424|M.smegmatis_MC2_155 RTEPAVFVWLGVIFYLTPDAAGSTLDYIAGQARP-VDLVFDYLQPAETDE
Mb2772|M.bovis_AF2122/97 TEYRVFFVCEGVTQYLTERAVRRTLEGLR-AAAPGSRMVFTYVRRDFIDG
Rv2751|M.tuberculosis_H37Rv TEYRVFFVCEGVTQYLTERAVRRTLEGLR-AAAPGSRMVFTYVRRDFIDG
MMAR_1964|M.marinum_M TDFRVFFICEGVTQYLTEETVRRTLEGLR-AAAPGSRLVFTYVRRDFIDG
MUL_3393|M.ulcerans_Agy99 TDFRVFFICEDVTQYLTEETVRRTLEGLR-AAAPGSRLVFTYVRRDFIDG
MAV_3642|M.avium_104 TDYRVFFICEGVTQYLSEATVRRTLDGLR-AAAPGSRLVFTYVRSDFIDG
Mflv_3997|M.gilvum_PYR-GCK TRARTFFSRAPLTPF--PDAVRATLTQLD-GAAEGSKLIFSYIRQDFIDG
Mvan_2390|M.vanbaalenii_PYR-1 PEQRTFFIWEGVTQYLSPEAVHATLAQLA-GAAPGSKLVFTYIRQDFIDG
MLBr_02020|M.leprae_Br4923 PQRSSAWSVEGLLPYLTNDAQSALFTRIGELCAPGSRIAVG-ALGSRLDR
TH_4502|M.thermoresistible__bu PQQRTAWLAEGLLMYLPADAQDRLFENITALSAPGSRLAVETAAEEPVDR
: : : : : . : .
MAB_2209c|M.abscessus_ATCC_199 DSTSLRARLWTQAAA------RFGEPYLTGLTATGADALLAAHGFTCEAH
MSMEG_3424|M.smegmatis_MC2_155 DRADLKN--RAARLA------RAGEPLVNYLTSDELHRQLADFGFRVVED
Mb2772|M.bovis_AF2122/97 -TNRYGTRTLYHTVR------QRRQLWHFGLDPEEVAGFLADYGWRLTEQ
Rv2751|M.tuberculosis_H37Rv -TNRYGTRTLYHTVR------QRRQLWHFGLDPEEVAGFLADYGWRLTEQ
MMAR_1964|M.marinum_M -TNRYGTRTLYRSVR------QRRQLWHFGLLPDEVPEFLAEYGWRLVEQ
MUL_3393|M.ulcerans_Agy99 -TNRYGTRTLYRSVR------QRRQLWHFGLLPDEVPEFLAEYGWRLVEQ
MAV_3642|M.avium_104 -TNRYGTRTLYRNVR------QRRQLWHFGLQPGEVADFLAEYGWRLVEQ
Mflv_3997|M.gilvum_PYR-GCK -TDLYGARSVYRRFR------QRRAVWKSGLVPEHVGELLADHGWRLVEQ
Mvan_2390|M.vanbaalenii_PYR-1 -TNLYGADAVYRRFR------KRSQVWRSGVVPEQVGELLAGHGWRLVEQ
MLBr_02020|M.leprae_Br4923 KQ--LAALEATHPGVNISGDVDFSALTYEP--KTDSAQWLAAHGWAVEPV
TH_4502|M.thermoresistible__bu REQMRARMERIASQFGLEKALDVAQLMYDDPDRADVPEWLTGHGWRTEWV
*: .*:
MAB_2209c|M.abscessus_ATCC_199 LT-----TRELLQHYASADVGRSSVDGRAAITTAQRS------
MSMEG_3424|M.smegmatis_MC2_155 LS-----GNELIGRYPHGAPVLDERALRASRIVHARC------
Mb2772|M.bovis_AF2122/97 AG-----PEELVQRYVEPTGRNLNASQIEWSAYAEKSEPVTPR
Rv2751|M.tuberculosis_H37Rv AG-----PEELVQRYVEPTGRNLNASQIEWSAYAEKSEPVTPR
MMAR_1964|M.marinum_M AG-----PDELVQRYVEPAGRKLNASQIEWSAYAEKL------
MUL_3393|M.ulcerans_Agy99 AG-----PDELVQRYVEPAGRKLNASQIEWSAYAEKL------
MAV_3642|M.avium_104 AG-----PDELMQRYVVPTGRKLKASQLEWSAYAEKT------
Mflv_3997|M.gilvum_PYR-GCK AG-----PSYYRDTYIRPTGRPLAASPLEWTVFAER-------
Mvan_2390|M.vanbaalenii_PYR-1 AG-----PSYFRDTYIRPTGREVSASPVEWTVLAER-------
MLBr_02020|M.leprae_Br4923 RN-----TLELQTSYGMTPPD--VDVQMDSFMHSQYITATR--
TH_4502|M.thermoresistible__bu SAPDEMRRLDRFVAAAMPPGDDADAADLDDTAFSKFVTAERPS