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LGLGSAASGTGADRGAWTLAEPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEF YDPQPGVPGRTVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSAT GVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGLTAVHMACRSL HEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDR ILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYASVSEVY GVDGPCALASVKTNFGHTQSTAGVLGLIKVVLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPT NGRQVPRRAAVSSYGFSGTNVHAVVEQAPQTEAQPHAASTPPTGTPALFTLSASSADALRQTAQRLTDWI QQHADSLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWLFSGQG SQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPTIFAMQVALAATMAAY GVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIAGSAAMASVELPALAVQSELTALGIDD VVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVLARAVAVDVASHSPQVDPILDELIAALADLNPKAPEI PYYSATLFDPREAPACDARYWADNLRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPV AALAGMRREQPLPLGLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGST VAVHPLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGEQSEVRD MRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSGECEPPAYDMASLLEAH PCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEVALPGSIRSQQGLYAIHPALLDACFQS VGAHPDSQSVGSGLLVPLGVRRVRAYAPVRTARYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIG TGVSERDKHNRVLNERLLTIEWHQRELPEMDPSGAGKWLLISDCAASDVTATRLADAFREHSAACTTMRW PLHDDQLAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVPRMYV VTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLLATSEEDETAWRDNE WYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAFHRVPPGPGQIEVAVRASSVNFADV LIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHKVGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGD AQAAAVTTAHATAWYGLHELARIRAGDTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMG IEHVYDSRSIEFAEQIRRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFR RNLSFYAVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKLVLHI PQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQPTQKMRETIEAIAA MGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDATLANITDELLARDWAPKVHGAWELH EATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWLDAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSAS PARASALEESNYTAITPDEGAYAFEALLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSSNGSGTSKF RVELNELPRDEWPARLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSA TVRGLADHLYEQLAPDDAPAAALSSQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3855c | pks2 | - | 100% (2126) | polyketide synthase PKS2 |
| M. bovis AF2122 / 97 | Mb1554c | pks5 | 0.0 | 69.91% (2117) | polyketide synthase pks5 |
| M. bovis AF2122 / 97 | Mb2965c | mas | 0.0 | 63.94% (2124) | multifunctional mycocerosic acid synthase membrane-associated |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 33.29% (2202) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv3825c | pks2 | 0.0 | 100.00% (2126) | polyketide synthase PKS2 |
| M. leprae Br4923 | MLBr_00139 | mas | 0.0 | 63.14% (2127) | putative mycocerosic synthase |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 60.89% (2099) | polyketide synthase Pks5 |
| M. marinum M | MMAR_2340 | pks5 | 0.0 | 69.55% (2105) | polyketide synthase Pks5 |
| M. avium 104 | MAV_2370 | - | 0.0 | 68.64% (2111) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 65.02% (2127) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 66.14% (1822) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2010 | mas | 0.0 | 65.56% (2108) | multifunctional mycocerosic acid synthase membrane-associated |
| M. vanbaalenii PYR-1 | Mvan_0269 | - | 0.0 | 33.64% (2188) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDR
Mvan_0269|M.vanbaalenii_PYR-1 MGSAEHPNGPAPRFAIVGYAARFPGAPDADAFWDVLREGRDAISDVPRDR
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK WDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQH
Mvan_0269|M.vanbaalenii_PYR-1 WDAEEFFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQH
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RLLLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGMASDELSYPEI
Mvan_0269|M.vanbaalenii_PYR-1 RLLLETAWRAVEHSGTAPTALAGSNTGVFVGLATHDYLGMASDELTYPEI
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mvan_0269|M.vanbaalenii_PYR-1 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mvan_0269|M.vanbaalenii_PYR-1 GECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
Mvan_0269|M.vanbaalenii_PYR-1 CGVIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIA
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLI
Mvan_0269|M.vanbaalenii_PYR-1 DALKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPSRPLLI
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLP
Mvan_0269|M.vanbaalenii_PYR-1 GSAKTNIGHLEAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLA
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAHVILEEAP-LAAEPAQ
Mvan_0269|M.vanbaalenii_PYR-1 VEVVKETIPWER---DGGPRIAGVSSFGFAGTNAHVILEEAPEQAAAPGP
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLADLCFTAGTA
Mvan_0269|M.vanbaalenii_PYR-1 VQQPDRRFSLLPLSARTPAALTQLAGQYRDWWTAHPEATLADVCFTAGAG
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHDTPKTAWLFT
Mvan_0269|M.vanbaalenii_PYR-1 RAHLEHRAALVVNSAESAVELLGALADDRPAPGLVRGESHDTPKTAWLFT
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVL
Mvan_0269|M.vanbaalenii_PYR-1 GQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE---
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAA
Mvan_0269|M.vanbaalenii_PYR-1 ADDAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAA
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPA
Mvan_0269|M.vanbaalenii_PYR-1 CVAGVFSLTDGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEFPS
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LSVAAYNGANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDP
Mvan_0269|M.vanbaalenii_PYR-1 LSVAAYNGTNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALLDP
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ILDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVE
Mvan_0269|M.vanbaalenii_PYR-1 ILDDFESYANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQPVE
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPRVIASLRRTT
Mvan_0269|M.vanbaalenii_PYR-1 FAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAPRVIASLRRTA
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDS
Mvan_0269|M.vanbaalenii_PYR-1 ADHRQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFRDN
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK REP--VAAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLNRL
Mvan_0269|M.vanbaalenii_PYR-1 QDPDGSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTLDVLSRL
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDAT
Mvan_0269|M.vanbaalenii_PYR-1 AAQHNQQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVGDDTEAT
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHVAA
Mvan_0269|M.vanbaalenii_PYR-1 RPLVDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLRIVHVGG
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LDAAES---DTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGA
Mvan_0269|M.vanbaalenii_PYR-1 LDSDPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIWVVTRRA
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLN
Mvan_0269|M.vanbaalenii_PYR-1 QHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADEWSRLLN
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADATYLVT
Mvan_0269|M.vanbaalenii_PYR-1 RITAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDDATYLVT
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERHGCEVR
Mvan_0269|M.vanbaalenii_PYR-1 GGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRIDALGAQHSCQIR
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVD
Mvan_0269|M.vanbaalenii_PYR-1 VVAADVADAHDVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSLEDSEVD
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWGGFGQAAYGAANAFL
Mvan_0269|M.vanbaalenii_PYR-1 RVFAGKVWGAWHLSEAAADLQLDFFLGTSSIASVWGGYGQTAYGAANAFL
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTLSPADALA
Mvan_0269|M.vanbaalenii_PYR-1 DGLAWRLREQGISGVSINFGPWSAGMADAESRARLDQRGVRTLSPADALA
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLSDAVISAAP----HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAA
Mvan_0269|M.vanbaalenii_PYR-1 GLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRRAFLAELEREVPDT
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK PAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAE
Mvan_0269|M.vanbaalenii_PYR-1 ----APAATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAEITRVDATE
Mb3855c|M.bovis_AF2122/97 --------------------------------------------------
Rv3825c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK IREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYL
Mvan_0269|M.vanbaalenii_PYR-1 IREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPRLSDVADYL
Mb3855c|M.bovis_AF2122/97 ----MGLGSAASGTGADRGAWTLAEPRVTPVAVIGMACRLPGGIDSPELL
Rv3825c|M.tuberculosis_H37Rv ----MGLGSAASGTGADRGAWTLAEPRVTPVAVIGMACRLPGGIDSPELL
MMAR_2340|M.marinum_M ---------------------------MTPVAVIGMACRLPGGIGSPEEL
MAV_2370|M.avium_104 ---------------------------MVPVAVIGMACRLPGAVDSPERL
MLBr_00139|M.leprae_Br4923 -----------------------METSVTPIAVIGMGCRLPGGINSPDKL
MUL_2010|M.ulcerans_Agy99 -----------------------MQKSATPVAIIGMGCRLPGGVDSPEKL
MSMEG_4727|M.smegmatis_MC2_155 ----------------------MTQNCVAPVAIIGMACRLPGAINSPQQL
MAB_3148c|M.abscessus_ATCC_199 -----------------------------------MGCRLPGGIESPEQF
TH_4621|M.thermoresistible__bu -------------------VNIVGDTPVNAVAVIGMACRLPGGIDSPQRL
Mflv_0405|M.gilvum_PYR-GCK LGDVLGLTEAATAPKAATVVSTAA---DEPIAIVAVSCRFPGAPN-PEAF
Mvan_0269|M.vanbaalenii_PYR-1 LGEVLGLAEQAPAKAGSQPASAAANRTDEPIAIVAVSCRFPGAPD-PEAF
:.**:**. *: :
Mb3855c|M.bovis_AF2122/97 WKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGRTVCKWGGFLDNPADFD
Rv3825c|M.tuberculosis_H37Rv WKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGRTVCKWGGFLDNPADFD
MMAR_2340|M.marinum_M WEALLRGDDLVTEIPADRWDADEYYDPEPGVPGRTVCKWGAFLDNVGDFD
MAV_2370|M.avium_104 WEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSRWGAFIDDVAGFD
MLBr_00139|M.leprae_Br4923 WESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVSRWGGFLDDVAGFD
MUL_2010|M.ulcerans_Agy99 WESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDVAGFD
MSMEG_4727|M.smegmatis_MC2_155 WEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFLDDPAAFD
MAB_3148c|M.abscessus_ATCC_199 WQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSKWGAFLEDVGGFD
TH_4621|M.thermoresistible__bu WEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDVAGFD
Mflv_0405|M.gilvum_PYR-GCK WDLLSGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFD
Mvan_0269|M.vanbaalenii_PYR-1 WEVLAGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFD
*. * * : : *:* *:* :::**:....*:: ::*.*:: **
Mb3855c|M.bovis_AF2122/97 CEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSATGVFAGV
Rv3825c|M.tuberculosis_H37Rv CEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSATGVFAGV
MMAR_2340|M.marinum_M PEFFGITEKEAIAIDPQHRMLLETAWEAMEHGGLTPEQMAESLTGVFVGL
MAV_2370|M.avium_104 PEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTGVFIGL
MLBr_00139|M.leprae_Br4923 AEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVFTGL
MUL_2010|M.ulcerans_Agy99 AEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTGVFVGL
MSMEG_4727|M.smegmatis_MC2_155 PEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSATGVFMGL
MAB_3148c|M.abscessus_ATCC_199 ADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGVFVGV
TH_4621|M.thermoresistible__bu PEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGL
Mflv_0405|M.gilvum_PYR-GCK PEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGV
Mvan_0269|M.vanbaalenii_PYR-1 PEFFGISPREAVWIEPQQRLMLETVWEGLERAGLAPADLRGSRTGIFVGV
:**.: :** ::**:* :*** *:.:*:.* : * *.:* *:
Mb3855c|M.bovis_AF2122/97 THGDYTMVA-ADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTA
Rv3825c|M.tuberculosis_H37Rv THGDYTMVA-ADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTA
MMAR_2340|M.marinum_M NHGDYQFVH-VDANTFDGPYGNTGTNSCFASGRISYAMRLHGPAVTVDTA
MAV_2370|M.avium_104 THGDYQLLA-ADTRSVEGAYGFSGSNFSLASGRIAYALGVHGPALTVDTA
MLBr_00139|M.leprae_Br4923 THEDYLVLT-TAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTA
MUL_2010|M.ulcerans_Agy99 SHEDYLVRS-VLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTVDTA
MSMEG_4727|M.smegmatis_MC2_155 THNDYAHLA-ADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAITVDTA
MAB_3148c|M.abscessus_ATCC_199 THNDYQLVA-ADAADLGGPYGFAGTNFCMASGRISYALGVHGPSLTVDAG
TH_4621|M.thermoresistible__bu SHDDYALLT-SDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTA
Mflv_0405|M.gilvum_PYR-GCK AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
Mvan_0269|M.vanbaalenii_PYR-1 AANEYAHLLSSESIEKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
:* : .: * ***::. : :.**:::.*:.
Mb3855c|M.bovis_AF2122/97 CSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTG
Rv3825c|M.tuberculosis_H37Rv CSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTG
MMAR_2340|M.marinum_M CSSSLYATHLACNSLSEGESDLAFAAGVYVMLEPRRFASGSAQNMLSPTG
MAV_2370|M.avium_104 CSSGLTAIHLACRSLHEGESDLALAGGATLALDPRKFSAGSAEGMLSPTG
MLBr_00139|M.leprae_Br4923 CSSGLMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTG
MUL_2010|M.ulcerans_Agy99 CSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLSPTG
MSMEG_4727|M.smegmatis_MC2_155 CSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGMLSPTG
MAB_3148c|M.abscessus_ATCC_199 CAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRMLSPTG
TH_4621|M.thermoresistible__bu CSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTG
Mflv_0405|M.gilvum_PYR-GCK CSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVG
Mvan_0269|M.vanbaalenii_PYR-1 CSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTSVAASRARMLSPVG
*::.* : * . .:* *:.*:.:*.* : *.* . * ***..*
Mb3855c|M.bovis_AF2122/97 RCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSANQDGH
Rv3825c|M.tuberculosis_H37Rv RCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSANQDGH
MMAR_2340|M.marinum_M HCHAFDVDADGFVSGEGSVVLLLKRLADAQRDGDRILAVMRGTAANQDGH
MAV_2370|M.avium_104 RCHAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRILAVVRGTAANQDGH
MLBr_00139|M.leprae_Br4923 RCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGG
MUL_2010|M.ulcerans_Agy99 RCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAANQDGR
MSMEG_4727|M.smegmatis_MC2_155 HCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTATNQDGR
MAB_3148c|M.abscessus_ATCC_199 RCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASNQDGR
TH_4621|M.thermoresistible__bu RCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGR
Mflv_0405|M.gilvum_PYR-GCK RCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGA
Mvan_0269|M.vanbaalenii_PYR-1 RCKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRVCAVIPSSAVNQDGA
:*::* ***:* .**. :: **** ** *.:*: *:: .:: ****
Mb3855c|M.bovis_AF2122/97 TVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYAS
Rv3825c|M.tuberculosis_H37Rv TVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYAS
MMAR_2340|M.marinum_M TVNIATPSVEAQSAVYRAALATAGVDGASVGLVEAHGTGTPVGDPIEFES
MAV_2370|M.avium_104 TVNIATPSKTAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGDPIEYAS
MLBr_00139|M.leprae_Br4923 TETLMMPSEDAQVAVYQAALAVAGVEPETIGVVEAHGTGTPIGDPIEYRS
MUL_2010|M.ulcerans_Agy99 SETLLMPSETAQVAVYREALAAAGVDAASVGAVEVHGTGTPVGDPIEYRS
MSMEG_4727|M.smegmatis_MC2_155 TVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGDPLEFSS
MAB_3148c|M.abscessus_ATCC_199 TVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPIEYTG
TH_4621|M.thermoresistible__bu TENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNS
Mflv_0405|M.gilvum_PYR-GCK SSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQA
Mvan_0269|M.vanbaalenii_PYR-1 SSGLTVPNGGAQQRLIGMALARAGLSGGDVDYLEAHGTGTPLGDPIEVQA
: *. ** .* .*: :. :*.**.***:***:* .
Mb3855c|M.bovis_AF2122/97 VSEVYGVD----GPCALASVKTNFGHTQSTAGVLGLIKVVLALKHGVVPR
Rv3825c|M.tuberculosis_H37Rv VSEVYGVD----GPCALASVKTNFGHTQSTAGVLGLIKVVLALKHGVVPR
MMAR_2340|M.marinum_M LARVYGID----RPCALTSAKPNFGHMQAGAGVLGLMKAILALQHGVIPP
MAV_2370|M.avium_104 LAEVYGID----GPCALASVKTNFGHAQAASGALGMMKAILALQHGVVPR
MLBr_00139|M.leprae_Br4923 LARVYGAG----TPCALGSAKSNMGHSTASAGTVGLIKAILSLRNGLVPP
MUL_2010|M.ulcerans_Agy99 LAQVYGSGG---SRCMLGSVKTNIGHSESAAGTVGLIKATLSLGHGVVPP
MSMEG_4727|M.smegmatis_MC2_155 LAEVYGTD----GPCALGSIKTNFGHTQSAAGALGVMKAVLALQHNVIPQ
MAB_3148c|M.abscessus_ATCC_199 LAQVYGVD----GPCAVGSVKTNFGHTMSAAGALGLMKIVLAVEHGVVPP
TH_4621|M.thermoresistible__bu LTQVYGKT----GPCALTSVKTNFGHAESAAGALGMMKAILALQHGVVPQ
Mflv_0405|M.gilvum_PYR-GCK AAAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQ
Mvan_0269|M.vanbaalenii_PYR-1 AAAAYGASRDADRPLLMGSVKTNIGHLESASGAAGLIKVVLSLQHNLLPQ
: .*. : * *.*:** : :*. *::* *:: : :*
Mb3855c|M.bovis_AF2122/97 NLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTNV
Rv3825c|M.tuberculosis_H37Rv NLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTNV
MMAR_2340|M.marinum_M NIHFSRLPDEMAQIKSGLFVPQEITQWPTNGEQT-RTAAVSSYGISGTNV
MAV_2370|M.avium_104 NLHFTQLPDDLARIDTKLFVPQQTTPWVSNGGHP-RRAAVSSYGLSGTNV
MLBr_00139|M.leprae_Br4923 LLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV
MUL_2010|M.ulcerans_Agy99 MVHHTRLPDELAEIETGLYVPHEITPWPED--QGPRRIAVSSFGMSGTNV
MSMEG_4727|M.smegmatis_MC2_155 NLHFTRLPDQMAEIETGLFVPETITPWPVREGQP-RRAAVSAYGLSGTNV
MAB_3148c|M.abscessus_ATCC_199 NLHFTGIPDKLAPVKTNLFVPQTVIPWPGKAQGP-RRAGVSAYGMSGSNV
TH_4621|M.thermoresistible__bu NLHFTRLPDEMAAIETNLFVPQATTLWPVREGCP-RRAAVSSYGMSGTNV
Mflv_0405|M.gilvum_PYR-GCK SLHFDTPSPHIPWDSLPVRVVDTAMPWQPNGRPR--RAGVSSFGFTGTNA
Mvan_0269|M.vanbaalenii_PYR-1 SLHFENPSPHIPWDSLPVRVVDKAIPWQADGRPR--RAGVSSFGFTGTNA
:*. . .:. : * . * .**::*::*:*.
Mb3855c|M.bovis_AF2122/97 HAVVEQAPQTEA-------QPHAASTPPT-----GTPALFTLSASSADAL
Rv3825c|M.tuberculosis_H37Rv HAVVEQAPQTEA-------QPHAASTPPT-----GTPALFTLSASSADAL
MMAR_2340|M.marinum_M HAILEQAPETAT-------HDAEPVSPAI-----EGALIFPLSATSADGL
MAV_2370|M.avium_104 HAILEQAPEPAP-------ETVAPEGISA-----ESPLLFPLSSTSADEL
MLBr_00139|M.leprae_Br4923 HVIVEEAPSEAC-------APDVPETSPGTGDATVGRQLFMLSSTSIAAL
MUL_2010|M.ulcerans_Agy99 HAILEEPPTPAP-------ARDQASAEPG----MASPLLFALSSTSADGL
MSMEG_4727|M.smegmatis_MC2_155 HAVLEQAPESPA-------ETAAEAISPK----AGNALVFPVSASSADAL
MAB_3148c|M.abscessus_ATCC_199 HAVVEQAPPVES-------STPPAVESPL-----GSQLIFPVSSTSAEEL
TH_4621|M.thermoresistible__bu HAVLEQAPEPVQ-------RPEESADTDA-----AGPLVFALSSTSAEEL
Mflv_0405|M.gilvum_PYR-GCK HVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSPEAL
Mvan_0269|M.vanbaalenii_PYR-1 HVLIEEAPLPQA--------ADPVEE---PDTRALPVGVLALSARSPEAL
*.::*:.* :: :*: * *
Mb3855c|M.bovis_AF2122/97 RQTAQRLTDWI------QQHADSLVLSDLAYTLARRRTHRSVRTAVIASS
Rv3825c|M.tuberculosis_H37Rv RQTAQRLTDWI------QQHADSLVLSDLAYTLARRRTHRSVRTAVIASS
MMAR_2340|M.marinum_M RQTAKRLADWV------DAQGPELATSDLAYTLARRRGHRPVRTAVLADN
MAV_2370|M.avium_104 RRTAGRLADWV------HAHG-DLALPDLAYTLARRRVHRPVRTAVLAGD
MLBr_00139|M.leprae_Br4923 RETARQLATWV------EEHQDSVVLSDLAYTLARGRAHRPVRTAVVAAD
MUL_2010|M.ulcerans_Agy99 RQTARELAEWVGSR---ADSADSTEAVDLAYTLARRRAHRPVRTAVVAAS
MSMEG_4727|M.smegmatis_MC2_155 RSTAQHLADWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRAARSAVLAGD
MAB_3148c|M.abscessus_ATCC_199 RRTAARLADWV-------AERPEVAPGDVGYTLARRRAHRSVRTAVVADG
TH_4621|M.thermoresistible__bu RRTAGRLAEWV------EAHTDEVVPADLAYTLARRRAHRPVRTTVIADG
Mflv_0405|M.gilvum_PYR-GCK VALAQRYETWLT-------AHPEADLADVCRTAGTGRSHFEHRAALVVDS
Mvan_0269|M.vanbaalenii_PYR-1 TALAQRYEAWLS-------AHPDADLADVCRTAGTGRSHFEHRAALVVDS
* . *: *: * . * . *::::. .
Mb3855c|M.bovis_AF2122/97 VDELIAGLGEVADGDTVYQPAVGQDDRGP--VWLFSGQGSQWAAMGADLL
Rv3825c|M.tuberculosis_H37Rv VDELIAGLGEVADGDTVYQPAVGQDDRGP--VWLFSGQGSQWAAMGADLL
MMAR_2340|M.marinum_M VSELSAGLHEIADDETPYQAAVGRDDRGP--VWVFSGQGSQWKAMGADLL
MAV_2370|M.avium_104 RAQLIEALREVADGDTPYPAAVGRGDRGP--VWVFSGQGSQWAAMGADLL
MLBr_00139|M.leprae_Br4923 LPELVEGLCEIADGDALYDAVVGHGDRGP--VWVFSGQGSQWASMGVQLL
MUL_2010|M.ulcerans_Agy99 LPELVEGLQEVAEGDLVYEAAVGRGDRGP--VWVFSGQGSQWAAMGADLL
MSMEG_4727|M.smegmatis_MC2_155 RGTLVEGLRQIADGEAMPQQAVTNDDRGP--VWVFSGQGSQWASMGAELL
MAB_3148c|M.abscessus_ATCC_199 ADELIDALRGVAEGDAPYPAAVAQDDRGP--VWLFSGQGSQWAGMGAELL
TH_4621|M.thermoresistible__bu VEALTAGLREVADGDAPYQPAVGMDDKAP--VWVFSGQGSQWAGMGAELL
Mflv_0405|M.gilvum_PYR-GCK VESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMARELF
Mvan_0269|M.vanbaalenii_PYR-1 VAAAREGLAELAQNRLRPGVVRGEHTHHPTTAWLFTGQGSQFPGMARELF
.* :*:. . . * .*:*:*****: .*. :*:
Mb3855c|M.bovis_AF2122/97 TNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTG---------IDRV
Rv3825c|M.tuberculosis_H37Rv TNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTG---------IDRV
MMAR_2340|M.marinum_M ANEPVFAATVAELEPLIAAESGFSVTEAMTAIETVTG---------IDRV
MAV_2370|M.avium_104 ATEPVFAATVAQAEPLIARESGFSVAEAMSAPQTVTG---------QDRV
MLBr_00139|M.leprae_Br4923 ANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTG---------IDKV
MUL_2010|M.ulcerans_Agy99 ANEPVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTG---------IDKV
MSMEG_4727|M.smegmatis_MC2_155 DREPAFAAAIAELEPLIAAESDFSVTEALTASETVTG---------IDRV
MAB_3148c|M.abscessus_ATCC_199 GKEPVFAETIARLEPLIHAESGFSVTDAISAPETVTG---------IDRV
TH_4621|M.thermoresistible__bu ATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG---------IDRV
Mflv_0405|M.gilvum_PYR-GCK DTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTSFA
Mvan_0269|M.vanbaalenii_PYR-1 ETEPVFADAVTRCADAVKDILPRPLLEVLFAADRESG----EALRHTSFA
* .** :: : .: :.: * :* . .
Mb3855c|M.bovis_AF2122/97 QPTIFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVR
Rv3825c|M.tuberculosis_H37Rv QPTIFAMQVALAATMA-AYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVR
MMAR_2340|M.marinum_M QPTIFTMQVALAATMK-SYGVRPGAIIGHSLGESAAAVAAGALSLEDGAK
MAV_2370|M.avium_104 QPTLFTMQVALAATMK-AHGVRPGAVIGHSLGEAAAAVVAGALSLEDGAR
MLBr_00139|M.leprae_Br4923 QPSVFAVQVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSLEDAAR
MUL_2010|M.ulcerans_Agy99 QPTLFAMQVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGAR
MSMEG_4727|M.smegmatis_MC2_155 QPTIFAVQVALAAAMR-SHGVVPGAVIGHSMGEVAASVVSGALSLEDGVK
MAB_3148c|M.abscessus_ATCC_199 QPTLFAMQVSLAATLA-SYGVRPGAVIGHSMGEVAAAVVSEALSLEDGVK
TH_4621|M.thermoresistible__bu QPTLFAIQVALAATMQ-SYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVK
Mflv_0405|M.gilvum_PYR-GCK QPALFAVEMGLARLWQ-SWGIVPDVVLGHSVGQYAAACVAGVFSLEDGAR
Mvan_0269|M.vanbaalenii_PYR-1 QPAIFAVEMGLARLWQ-SWGIEPDVVLGHSVGQYAAACVAGVFSLEDGAR
**::*::::.** : *: *..::***:*: **: .: :* **..:
Mb3855c|M.bovis_AF2122/97 VICRRSKLMATIAGSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQS
Rv3825c|M.tuberculosis_H37Rv VICRRSKLMATIAGSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQS
MMAR_2340|M.marinum_M VICRRSRLMTRISGSGAMASVELPAQQVLSELMARGINDVVVAVVASPQS
MAV_2370|M.avium_104 VICRRSRLMSRVAGTGATASVELPAQQVLSELTARGISDVVVAVVASPQS
MLBr_00139|M.leprae_Br4923 VICRRSKLMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQS
MUL_2010|M.ulcerans_Agy99 VISRRSKLMLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQS
MSMEG_4727|M.smegmatis_MC2_155 VICRRTRLMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQS
MAB_3148c|M.abscessus_ATCC_199 VICRRSQLMLRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQS
TH_4621|M.thermoresistible__bu VICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPES
Mflv_0405|M.gilvum_PYR-GCK LMAERGRLFGSLPEGGRMVAVFADAKRVEQVAAD--FPRVSVGAYNGP-N
Mvan_0269|M.vanbaalenii_PYR-1 LMAERGRMFGSLPEGGRMVAVFTDAKLVEEIAGD--FPRVSVGAYNGP-N
::..* :: :. . : * * . . * :.. .* .
Mb3855c|M.bovis_AF2122/97 TVIAGGTESVRKLVDIWERRDVLARAVAVDVASHSPQVDPILDELIAALA
Rv3825c|M.tuberculosis_H37Rv TVIAGGTESVRKLVDIWERRDVLARAVAVDVASHSPQVDPILDELIAALA
MMAR_2340|M.marinum_M TVIGGATDTVRELVAAWEQREVMAREVAVDVASHSPQVDPILDDLYDVLA
MAV_2370|M.avium_104 TVIAGAAPTVRDLVTAWQERGVMAREVPTDVAFHSPQVDPIMDDLTDALA
MLBr_00139|M.leprae_Br4923 TVIGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVDPILDDLAAALA
MUL_2010|M.ulcerans_Agy99 TVVGGATDTVRDLVARWEQREVMAREVAVDVASHSPQVDPILEDLATALA
MSMEG_4727|M.smegmatis_MC2_155 TVVGGATASVRELIEMWESRGVMAREIAVDVASHSPQVDPILDDLIEALA
MAB_3148c|M.abscessus_ATCC_199 TVVGGATETVRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALE
TH_4621|M.thermoresistible__bu TVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILA
Mflv_0405|M.gilvum_PYR-GCK TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAA
Mvan_0269|M.vanbaalenii_PYR-1 TVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLDEFESYAA
**:.* :..:: : : . : .. * ** :**:::::
Mb3855c|M.bovis_AF2122/97 DLNPKAPEIPYYS-ATLFDPREAPACDARYWADNLRHTVRFSAAVRSALD
Rv3825c|M.tuberculosis_H37Rv DLNPKAPEIPYYS-ATLFDPREAPACDARYWADNLRHTVRFSAAVRSALD
MMAR_2340|M.marinum_M DLEPLTPEVPYYS-ATLFDPREEPYCDGSYWVDNLRHTVRFGAAVQAALE
MAV_2370|M.avium_104 EISPRPPEVPYYS-ATLFDPREQPVCDARYWANNMRRMVRFATAVQAALE
MLBr_00139|M.leprae_Br4923 DIAPMTPKVPYYS-ATLFDPRELPVCNGAYWVDNLRNTVQFAAAVQAAME
MUL_2010|M.ulcerans_Agy99 DIVPSDPKVPYYS-ATLFDPRERPTCDAAYWVDNLRNTVQFAAAVQAALE
MSMEG_4727|M.smegmatis_MC2_155 DLDPAEPEIPYYS-ATLYDPRDYADYDAYYWADNLRHTVRFSAAVQAALE
MAB_3148c|M.abscessus_ATCC_199 DLTPRTPVVPLYS-SVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAALD
TH_4621|M.thermoresistible__bu DLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALE
Mflv_0405|M.gilvum_PYR-GCK QLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAA
Mvan_0269|M.vanbaalenii_PYR-1 QFQFATPTLPLVCNRTGTVLTAQTPLDAQYWRRHSRQPVQFAESVRTVAA
:: * :* . . . :. ** : *. *:*. :*::.
Mb3855c|M.bovis_AF2122/97 DGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPLGLRRLL
Rv3825c|M.tuberculosis_H37Rv DGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPLGLRRLL
MMAR_2340|M.marinum_M DGYRVFAELAPHPLLTRAVEKTAEGLDMPVAALAGMRREQPLPHGLRGLL
MAV_2370|M.avium_104 DGYRVFAELAPHPLLVRALEQTARSREIPMAALAGMRRGQALPHGLRGFV
MLBr_00139|M.leprae_Br4923 DGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLRGLL
MUL_2010|M.ulcerans_Agy99 DGFRVFAELSPHPLLTHAVDQNARSLDMSAAVLAGMRREQPLPHGLRGLL
MSMEG_4727|M.smegmatis_MC2_155 DGHRVFAELSPHPLLTHPVEQTARSLDMPLAVFAAMRRQQEMPHGLLGFV
MAB_3148c|M.abscessus_ATCC_199 DGYRVFGELAPHPLLVYPAEQTARSLDIPMVALAGMRREQELPHGLRDFV
TH_4621|M.thermoresistible__bu DGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMV
Mflv_0405|M.gilvum_PYR-GCK LGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQIADAL
Mvan_0269|M.vanbaalenii_PYR-1 LGCSVLMEIGPQPVLTGSAVQVWPEHLAAPRAIVSLRKGVSDRRQITEAL
* *: *:.*:*:*. . : . .: .:*: : :
Mb3855c|M.bovis_AF2122/97 TDLHNAGAAVDFSVLCPQ-GRLVDAPLPAWSHRFLFYDREGVDNRSPGGS
Rv3825c|M.tuberculosis_H37Rv TDLHNAGAAVDFSVLCPQ-GRLVDAPLPAWSHRFLFYDREGVDNRSPGGS
MMAR_2340|M.marinum_M ADLHSAGAAVDFSVLYPA-GELVDAPLPAWTHQSLLLNRAGQDHQAQGGS
MAV_2370|M.avium_104 ADLHNAGAAVDFSVLYPT-GRLVDAPLPTWTHRRLWLTDGGLESPTHGGC
MLBr_00139|M.leprae_Br4923 ADLHSAGAALDFAALYPA-GRLLDAPLPVWTHPRLFIDTDGQEQRAQGAC
MUL_2010|M.ulcerans_Agy99 TDVHSAGAAVDFSVLYPA-GRLVNAPPPAWTHRRFFVDGEGQDSKAQGAC
MSMEG_4727|M.smegmatis_MC2_155 ADLHSAGAAVDFSVLYPT-GRLLDAPLPAWTHSTLLLDR-ELESSAPGVP
MAB_3148c|M.abscessus_ATCC_199 GDLYTAGGAVDFSVLYPT-GQLVDVPLPSWTRRSYLLDLSAQAQQGHGTH
TH_4621|M.thermoresistible__bu GDLFAAGAAVDFAALYPS-GRLVDAPLPTWTRRKLVLSRENGEQQTRGGC
Mflv_0405|M.gilvum_PYR-GCK AAAYIGGHKPDFAALHEQRGVRLELPTYPFQRRRFWPKSAGMAIDGRVGA
Mvan_0269|M.vanbaalenii_PYR-1 AAAYVGGHRPDFGALYRRPGRAVALPTYPFQRRRFWPKTSGITTDG----
. .* **..* * : * : :
Mb3855c|M.bovis_AF2122/97 TVAVHPLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAA
Rv3825c|M.tuberculosis_H37Rv TVAVHPLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAA
MMAR_2340|M.marinum_M SVVVHPLLGSHVLLPEEPERHVWQSDVGTEALPWLADHQIHSAPALPGAA
MAV_2370|M.avium_104 TVAVHPLLGPHVHLQEEPERHLWQADVGTAAQPWLADHQIRNVVVLPGAA
MLBr_00139|M.leprae_Br4923 TVTVHPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAA
MUL_2010|M.ulcerans_Agy99 SVTVHPLLGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAA
MSMEG_4727|M.smegmatis_MC2_155 SVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAA
MAB_3148c|M.abscessus_ATCC_199 TVAVHPLLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAA
TH_4621|M.thermoresistible__bu TITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAA
Mflv_0405|M.gilvum_PYR-GCK SAGSG-ILGSGKDLASG--DSVYTSRLSVKTQPWLSDHVIYGTVVVPGAT
Mvan_0269|M.vanbaalenii_PYR-1 PAVSG-ILGSAKDLASG--DTVYTSRWSVRSQPWLADHVIYGTVVVPGAT
. :**. * . : .. .*:.** : . . ***:
Mb3855c|M.bovis_AF2122/97 YCEMALSAARAVLG-EQSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVD
Rv3825c|M.tuberculosis_H37Rv YCEMALSAARAVLG-EQSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVD
MMAR_2340|M.marinum_M YCEMALVAARTILG-DAAEVRDVRFEQMLLLDDETPLSAVGSVKSPGIVD
MAV_2370|M.avium_104 YCEMALAAARSVLG-ATAEVRDIRFEQALLLDEQTTVDASASVSSPGVLH
MLBr_00139|M.leprae_Br4923 YCEMALAAAVEVFG-EAAEVRAIAFEQMLLLAAETPIDAIASVDAPGVIN
MUL_2010|M.ulcerans_Agy99 YCEMALAAAGEVFG-EAFEVRDLAFEQMLLLDEETPIDAVASLDSPGAAN
MSMEG_4727|M.smegmatis_MC2_155 YCEMALAAVTPVLG-DTGEVHDLKFHDMLLLDDATPVWVSAAVTAPGTAE
MAB_3148c|M.abscessus_ATCC_199 YCEMALSAAAAVFG-EGSAVQSISFEQLLTLGESTPISATATAKSADILE
TH_4621|M.thermoresistible__bu YCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLE
Mflv_0405|M.gilvum_PYR-GCK YAAMALAAVGTPAH-----AKDVFFYEPIILPEKSSREVQLTVHPSVDGE
Mvan_0269|M.vanbaalenii_PYR-1 YAAMALAAVGTPAR-----VKDVFFYEPIILPEKASREVQLTLHPSEDGG
*. *** *. .: : * : * : . : .
Mb3855c|M.bovis_AF2122/97 FAVEALQEGV----GHHLRRASAVLQQVSGECEPPAYDMASLLEAHPCRV
Rv3825c|M.tuberculosis_H37Rv FAVEALQEGV----GHHLRRASAVLQQVSGECEPPAYDMASLLEAHPCRV
MMAR_2340|M.marinum_M FVVETFQD------GGAVRRGGAVLHAVEDDDQLPAYDIPALLAEHSRTE
MAV_2370|M.avium_104 FTVQSHQG------GEQARHASAVLGAATDE-QPAAHDLSALLTAHPHDD
MLBr_00139|M.leprae_Br4923 FVVQANQD------GEKMRNATATLHAAEDDCPPPAYDIAALLEAHPNSV
MUL_2010|M.ulcerans_Agy99 FVVQTHVD------GETTRHATAALRASDDESVPPAYDIAALLAAHPVSV
MSMEG_4727|M.smegmatis_MC2_155 FGVETHQS------GDRTQRATAVLRGDVDAERPAAHSIDALLAAHPNRV
MAB_3148c|M.abscessus_ATCC_199 FVVETHDE------GDVVKRATAVLGNGGDVDMPIAYDLSALRAEHPHRE
TH_4621|M.thermoresistible__bu FAVETAKD------GEHERRATAVLGAADDTEPPQAHDIDALLAEHPTRI
Mflv_0405|M.gilvum_PYR-GCK SKFQVHSRPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDEAIERL
Mvan_0269|M.vanbaalenii_PYR-1 QKFQVHSREYGERGTEWSLNAEGTVASGVDENPQAE--PSGPVDEAIERL
.: .. ..: .
Mb3855c|M.bovis_AF2122/97 D---GEDLRRQFDKHGVQYGPAFTG--LAVAYVAEDATATMLAEVALPGS
Rv3825c|M.tuberculosis_H37Rv D---GEDLRRQFDKHGVQYGPAFTG--LAVAYVAEDATATMLAEVALPGS
MMAR_2340|M.marinum_M D---GEELRARFDEHGVQYGPAFTG--LGNAHIADGAVSSVVAEVALPGA
MAV_2370|M.avium_104 D---GDEVRRRMDRRGVQYGPAFAG--LGAVHSGD-ETGTVLAEVALPRQ
MLBr_00139|M.leprae_Br4923 N---GTDLRESFAERGVQLGAAFAG--LATAHTAEAESGTVLAEVALPAS
MUL_2010|M.ulcerans_Agy99 N---GAELREAFVERGIQHGPAFSG--LAIARTAETEGGTVLAEVALPAS
MSMEG_4727|M.smegmatis_MC2_155 D---GDELRAGFGTVGIGHGAAFAG--LSEAYVATAAEPTVVAAVALPGP
MAB_3148c|M.abscessus_ATCC_199 S---GDDLRASFDERGVQYGPAFQG--LAAAYRGDETVRSVLAEVTLPRD
TH_4621|M.thermoresistible__bu E---GDELRQWFDQRGVQFGPAFTG--LTAARIPEGTVTSVLAEVGLPGQ
Mflv_0405|M.gilvum_PYR-GCK NRMRPQELFETFADLELAWGPTWSGSLKSLWLGEGEAIGDILVGAELAEQ
Mvan_0269|M.vanbaalenii_PYR-1 NRMRPQDLFETFADMELAWGPTWSGSLKSLWLGEGEAIGDILVGEELAEQ
. :: : : *.:: * ::. *.
Mb3855c|M.bovis_AF2122/97 IRSQQGLYAIHPALLDACFQSVGAHPDSQSVG-SG-LLVPLGVRRVRAYA
Rv3825c|M.tuberculosis_H37Rv IRSQQGLYAIHPALLDACFQSVGAHPDSQSVG-SG-LLVPLGVRRVRAYA
MMAR_2340|M.marinum_M MRSQQRAYAIHPALLDACFQAVGAHPDVQVAG-NGGLMLPLGVRQIRAYA
MAV_2370|M.avium_104 IRSQQAAYGAHPALLDACFQSVEAHPAVRALG-DGALGLVLGIRRLRAYG
MLBr_00139|M.leprae_Br4923 IRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRVYR
MUL_2010|M.ulcerans_Agy99 IRFQQGAYGVHPALLDACFQSVAAGVKSTGGG---GLLLPLGVRSLRAYG
MSMEG_4727|M.smegmatis_MC2_155 LRSGQRGYTVHPALLDACFQSVIAHPEVQNIA--SGMLLPLGVRRLRAYG
MAB_3148c|M.abscessus_ATCC_199 VRAQQGSYIVHPALLDACFQSVIALPDVQEAS-KDALPLPKGVRSLHAYE
TH_4621|M.thermoresistible__bu IRSQQAPYGIHPALLDACFQSVAAHPDVQGAG--SGLLLPLGVRRLQAFG
Mflv_0405|M.gilvum_PYR-GCK LGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSLQEKM
Mvan_0269|M.vanbaalenii_PYR-1 LGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVSDLFLPLRYGQVTLRDKM
: ...* :. * : : * ::
Mb3855c|M.bovis_AF2122/97 PVRTARYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERD
Rv3825c|M.tuberculosis_H37Rv PVRTARYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERD
MMAR_2340|M.marinum_M STRNAHYCYARVTSVDTSAVEADLDVLDEHGTVLVAVRGLQLGTGVSEEG
MAV_2370|M.avium_104 AARNAHYCYTRVTKADTSGVEADIDVLDEHGAVLLAVQGLRVGTSASESG
MLBr_00139|M.leprae_Br4923 PTRNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERG
MUL_2010|M.ulcerans_Agy99 PTRNAQYCYTRVTKADANGGEADLELLDEQGCVLLAVRGLRLGTGTSESG
MSMEG_4727|M.smegmatis_MC2_155 STRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQLGTGNSDKA
MAB_3148c|M.abscessus_ATCC_199 SARATQYCYTRVTKVVGNEVEADIDLLDETGSVLIAVRGFRFGTGSSDDE
TH_4621|M.thermoresistible__bu PTRGARYCYARVTDADGSKAEADLDVLDEHGNVLLRVQGLLMGGAAADGD
Mflv_0405|M.gilvum_PYR-GCK PRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRAPREAL
Mvan_0269|M.vanbaalenii_PYR-1 PRRFYCRATWHTSELDSETQVFDLDFLDRDGRHLGGIREFTVKRAPREAL
. * . : *:: ** * * : . . :
Mb3855c|M.bovis_AF2122/97 KH--NRVLNERLLTIEWHQRELPE---MDPSGAGKWLLIS---DCAASDV
Rv3825c|M.tuberculosis_H37Rv KH--NRVLNERLLTIEWHQRELPE---MDPSGAGKWLLIS---DCAASDV
MMAR_2340|M.marinum_M NR--DRVLNERLLTIEWQQRELPE---VDAAEAGAWLLIS---TSDGADM
MAV_2370|M.avium_104 TR--DRVLTERLLNIEWRQRELPE---PEHADAASWLLIG---TTATADV
MLBr_00139|M.leprae_Br4923 EL--DRQLSERLLTIGWQQRTLPE---SVHVEPGSWLLIDTFNASAIPDM
MUL_2010|M.ulcerans_Agy99 ER--DRVLSERLLTLEWQQRQLPE---VLDEETGSWLLIS---ASDGEDL
MSMEG_4727|M.smegmatis_MC2_155 EE--ERLLDERLLTIEWQQRELPRPEGSETVDAGSWLVILA--GDDDENP
MAB_3148c|M.abscessus_ATCC_199 QR--DQLLNNRLLAIEWQQQRLPE---SVSGAPRRWLLVS---TGESVDP
TH_4621|M.thermoresistible__bu DR--DRVLGERLLTIEWQRRDLPE----ADSAAGKWLLVS---TSATADV
Mflv_0405|M.gilvum_PYR-GCK LRGLGGDATRLLYTLGWHEVPVPE-SGDGAAPQGTWLIGG-------FDE
Mvan_0269|M.vanbaalenii_PYR-1 LRGLGGDATRLLYTLGWHEVPAPA-SGD-AALNGNWLIAG-------FDE
. * : *:. * **: :
Mb3855c|M.bovis_AF2122/97 TATRLADAFRE---HSAACTTMRWPL-HDDQLAAADQLRDQVGSDEFSGV
Rv3825c|M.tuberculosis_H37Rv TATRLADAFRE---HSAACTTMRWPL-HDDQLAAADQLRDQVGSDEFSGV
MMAR_2340|M.marinum_M LAAELTDALKL---HSAQCATTSWHENAADHAASAERLRNQLNAGGFHNA
MAV_2370|M.avium_104 LASTLADTLKN---HGAQCTTMAWPQ-QADHTAHAEQLRNQWRGDGFTGV
MLBr_00139|M.leprae_Br4923 WASTLTDALKSYGTQGTECTNLSWLI-QDDPVVSRERLGRQLRGRD--GV
MUL_2010|M.ulcerans_Agy99 MATTLADALKS---QGAECASMVWSA-QDDLAGGIEKLGAQLRARTNKGV
MSMEG_4727|M.smegmatis_MC2_155 RAAGVVSALIG---AGMPTTTMAWSH-DADHDAQAAALTARLDEQPLAGV
MAB_3148c|M.abscessus_ATCC_199 WAAELIDSLKVR---ESEVSLIQWRP-NTDRVAALKLLYDQLESGTFDGV
TH_4621|M.thermoresistible__bu SATRLSDALKQ---AGAESTSMCWPQ-QADHADNVDRFRAGI-ADGVTGV
Mflv_0405|M.gilvum_PYR-GCK LAVSVPG---------------CIPADR-TNPESLRQLLTDAHGRGLPFS
Mvan_0269|M.vanbaalenii_PYR-1 LAAGVPG---------------CIPFDRSTDPEPLGQLLAQAHERGIGFS
* : . :
Mb3855c|M.bovis_AF2122/97 VVLTGSNTGTPHQGSA----DRGAEYVRRLVGIARELSDLPGAVPRMYVV
Rv3825c|M.tuberculosis_H37Rv VVLTGSNTGTPHQGSA----DRGAEYVRRLVGIARELSDLPGAVPRMYVV
MMAR_2340|M.marinum_M VILLKPDSGDRDENSG----VEGVECVRHVVRVVRELPEIMGEAPRLFVV
MAV_2370|M.avium_104 VVLTGPKNGDNDQESA----LLSRDHVQHLVRIARELTDLPGEPPRLYVV
MLBr_00139|M.leprae_Br4923 VILCGPRAGAPDEQSL----LAAREQVRHLVRIIRELAELEGELPRLFVV
MUL_2010|M.ulcerans_Agy99 VIVCGPRSGDADEQSL----LQGREQVRHLVRITRGLAELEGELPRLFVV
MSMEG_4727|M.smegmatis_MC2_155 AVIVGDSETGTDAHDVGADARRGADHVRHLVRIARTLADAVGEPPRLYVV
MAB_3148c|M.abscessus_ATCC_199 LVVTAPGSEGGADRVV----LQGADQVRHLVRITRELVDLPGEPPRLFVV
TH_4621|M.thermoresistible__bu VVLTGPKNGNPDDAAAR----RGSDYVRHLVRITRELAEIDGDAPRLFVV
Mflv_0405|M.gilvum_PYR-GCK GVVWRAARSDGDESDAEVAARLEAEIAELLGAVHTVQGGEVKLPGGLWIV
Mvan_0269|M.vanbaalenii_PYR-1 GVVWRAAAPSADESSTAMAARIETEIADLLSAVHTVQNGAVKLPGGLWIV
:: : . : : :::*
Mb3855c|M.bovis_AF2122/97 TRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQT-GVEQ
Rv3825c|M.tuberculosis_H37Rv TRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQT-GVEQ
MMAR_2340|M.marinum_M TRGAQTVLGGESANLEQAGLRGLLRVIGAEYPHLHTTHVDVDEHS-GSEV
MAV_2370|M.avium_104 TRNAQTVLPNDVPNLGQAGLRGLVRVIGMEHPQLGAGQIDVDEST-DAQA
MLBr_00139|M.leprae_Br4923 TRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHT-DVER
MUL_2010|M.ulcerans_Agy99 TRQAQRVRPEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDVDEST-QAEQ
MSMEG_4727|M.smegmatis_MC2_155 THRSQHVLDTDEPYLEHSGLRGLIRVVGMEHPRLRATQIDVDDST-AHEA
MAB_3148c|M.abscessus_ATCC_199 TRNAQTVVDGDITNLEQAGLRGLVRVIGAEYPHLRVTHIDVDRHT-AAQN
TH_4621|M.thermoresistible__bu TRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDA-DLDR
Mflv_0405|M.gilvum_PYR-GCK TERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSPQAVQA
Mvan_0269|M.vanbaalenii_PYR-1 TERAVATESGEPVDPVQAALWGFGRTTINEEPALRCRLVDVDGSPEAVLA
*. : . : :..* *: *. * * * :* .
Mb3855c|M.bovis_AF2122/97 LARQLLATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRL
Rv3825c|M.tuberculosis_H37Rv LARQLLATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRL
MMAR_2340|M.marinum_M VARQLLSGSEEDETAWRCGQWYTARLSPMPLRPEERKTTVVEHDTEGMRL
MAV_2370|M.avium_104 LARQLLAGSEEDETAWRDGAWYTARLCPAPLLPEERHTAVANHECDGMRL
MLBr_00139|M.leprae_Br4923 VAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRV
MUL_2010|M.ulcerans_Agy99 LAQQLLGGSEEDETAWRGGEWYVARLFPGPLSADERQTTVVDHERDNMRL
MSMEG_4727|M.smegmatis_MC2_155 LVRQLLSGSPEDETAWRDGQWYAARLCPSPLRAAERRTAVADNASEGMRL
MAB_3148c|M.abscessus_ATCC_199 VAGELVSGSEEDETAWREDHWYRARLNLGPLGPDDWRSTVATPNNEGVRF
TH_4621|M.thermoresistible__bu VAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDGMRL
Mflv_0405|M.gilvum_PYR-GCK LAALLSTPVDEPELAVRQGKLLASRLLP-----WSRSGHLTVPRGGDYVL
Mvan_0269|M.vanbaalenii_PYR-1 LAGLLAAPVDEPELAVRQGKLLASRLLP-----WARSGHLTVPRSADYVL
:. * * * * * . :** : . .
Mb3855c|M.bovis_AF2122/97 QIRTPGDMQTIELAAFHRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSF
Rv3825c|M.tuberculosis_H37Rv QIRTPGDMQTIELAAFHRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSF
MMAR_2340|M.marinum_M QIRTPGDLQTMEFVAFDRVAPGPGQIEVAVSTSSINFADVLVSFGRYNSP
MAV_2370|M.avium_104 QIRTPGDLESLELVACDRIPPGPGQIEVAVSASSINFADVLVAFGRYPAF
MLBr_00139|M.leprae_Br4923 HVRKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPII
MUL_2010|M.ulcerans_Agy99 QIRTPGDLQTLELAACDRVPPGPGQIEVAVTMSSINFADVLIAFGRYPSL
MSMEG_4727|M.smegmatis_MC2_155 VVRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFADVLVAFGRCPSF
MAB_3148c|M.abscessus_ATCC_199 EVRTPGDLQSLGFVAFDRVAPGPGQIEVSVTATSINFADVLNVYGRYSSF
TH_4621|M.thermoresistible__bu EIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVLIAFGRYPTF
Mflv_0405|M.gilvum_PYR-GCK APTERGAIDNLRLTDSEVPPPAEGYVQVRVEAAGLNFRDVLNVLGLYP--
Mvan_0269|M.vanbaalenii_PYR-1 APTERGAIDNLRLTETDVAPPAEGYVQVRVEAAGLNFRDVLNVLGLYP--
* ::.: :. . .*. * ::* * :.:** *** *
Mb3855c|M.bovis_AF2122/97 EGHLPQLGTDFAGVVTAVGPGVTDHKVGDHVGGMSPNGCWGTFVTCDARL
Rv3825c|M.tuberculosis_H37Rv EGHLPQLGTDFAGVVTAVGPGVTDHKVGDHVGGMSPNGCWGTFVTCDARL
MMAR_2340|M.marinum_M DGQMPQLGTDFAGVVTAVGPDVTDHQVGDRVGGMSPHGCWATFVTCDGAL
MAV_2370|M.avium_104 EGRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWGTFLTCDARL
MLBr_00139|M.leprae_Br4923 DDRDPQLGMDFVGVVTAVGEGVTGHQIGDRVGGFSEGGCWRTFLTCDANL
MUL_2010|M.ulcerans_Agy99 EGRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDGCWRSYLTCDANL
MSMEG_4727|M.smegmatis_MC2_155 DGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGCWSNFVTCEADL
MAB_3148c|M.abscessus_ATCC_199 EGR-QELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGAWRSFVVVDANL
TH_4621|M.thermoresistible__bu DGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCDADL
Mflv_0405|M.gilvum_PYR-GCK -GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQG-AFASRFNVPGQF
Mvan_0269|M.vanbaalenii_PYR-1 -GDPGPIGGDFAGTVTQLGSGVTGLEVGQRVYGFMQG-AFASRFNVPAQL
. * :* *.** :* .** :*::* * .: . . . :
Mb3855c|M.bovis_AF2122/97 AATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAGDTVLIHSGTGGVGQ
Rv3825c|M.tuberculosis_H37Rv AATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAGDTVLIHSGTGGVGQ
MMAR_2340|M.marinum_M ATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGDKVLIHSGTGGVGQ
MAV_2370|M.avium_104 AVTLPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLIHSATGGVGQ
MLBr_00139|M.leprae_Br4923 AVTLPSGLTDEQAITAATAHATAWYGLNDLAGIKVGDKVLIHSATGGVGQ
MUL_2010|M.ulcerans_Agy99 AVTLPAGLSDEHAAASSTAHATAWYGLNDLAGIKAGDRVLIHSATGGVGQ
MSMEG_4727|M.smegmatis_MC2_155 ATKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDKILIHSATGGVGQ
MAB_3148c|M.abscessus_ATCC_199 AATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKVLIHSGTGGVGQ
TH_4621|M.thermoresistible__bu AVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGVGL
Mflv_0405|M.gilvum_PYR-GCK LAPIPDGVSAVEAATIPAAALTVRL-SFDWAQVKSGDKVLIHAASGGVGL
Mvan_0269|M.vanbaalenii_PYR-1 LAPIPDGIGAVDAATIPAAALTARL-AFDWAQLKPGDRVLIHAASGGVGL
. :* : .* : * *. : . : *: :***:.:****
Mb3855c|M.bovis_AF2122/97 AAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQIRRDT
Rv3825c|M.tuberculosis_H37Rv AAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQIRRDT
MMAR_2340|M.marinum_M AAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRSIEFAEAIRADT
MAV_2370|M.avium_104 AAIAIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFADLIRHDT
MLBr_00139|M.leprae_Br4923 AAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRDT
MUL_2010|M.ulcerans_Agy99 AAIAIARAAGAQIFATAGNAERRQLVNDMGIEHVYDSRSIEFADQIRRDT
MSMEG_4727|M.smegmatis_MC2_155 AAIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVYDSRTTAFADQIRTDT
MAB_3148c|M.abscessus_ATCC_199 AAIAIARAAGAEIYATAGSPERRDLLRSWGIKHVYDSRSTDFAELIRRDT
TH_4621|M.thermoresistible__bu AAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRSTAFADEIRRDT
Mflv_0405|M.gilvum_PYR-GCK AAVQMAQQCGAEVYATASTFKR-ATLRKLGVKHVYDSRTTDFAEQILADT
Mvan_0269|M.vanbaalenii_PYR-1 AAIQMAQQHGAVVFATASTYKR-ATLRKLGVDHVYDSRTTEFADQILADT
**: :*: ** ::***.. : :.. *:.******: **: * **
Mb3855c|M.bovis_AF2122/97 NGRGVDVVLNSVTGAAQLAG-LKLLAFRGRFVEIGKRDIYGDTKLGLFPF
Rv3825c|M.tuberculosis_H37Rv NGRGVDVVLNSVTGAAQLAG-LKLLAFRGRFVEIGKRDIYGDTKLGLFPF
MMAR_2340|M.marinum_M DGYGVDIVLNSLTGAAQRAG-LELLAWGGRFVEIGKRDIYGDTKMGLFPF
MAV_2370|M.avium_104 DGYGVDIVLNSVTGAAQRAG-IELLAFGGRFVEIGKRDIYGDTRLGLLPF
MLBr_00139|M.leprae_Br4923 DGYGVDIVLNSLTGAAQRAG-LELLTFGGRFVEIGKADVYGNTRLGLFPF
MUL_2010|M.ulcerans_Agy99 NGYGVDIVLNSLTGAAQRAG-LELLAFGGRFVEIGKADVYGNTRMGLYPF
MSMEG_4727|M.smegmatis_MC2_155 DGYGVDIVLNSVTGPAQRAG-LELLAFGGRFVEIGKRDIYADTRLGLFPF
MAB_3148c|M.abscessus_ATCC_199 DGYGVDIVLNSLTGAAQRAG-VELLTFGGRFIEIGKRDIYGDTRLGLFPF
TH_4621|M.thermoresistible__bu DGYGVDVVLNSLPGAAQRAG-LELLSFGGRFIEIGKRDIYGDTRLGLFPF
Mflv_0405|M.gilvum_PYR-GCK DGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTVEQMAAA--
Mvan_0269|M.vanbaalenii_PYR-1 DGEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIAKRDIWTPEQMAAA--
:* ***:****:.. . . :. : *** **.* *:: ::.
Mb3855c|M.bovis_AF2122/97 RRNLSFYAVDLGLLSATHPEELRDLLGTVYRLTAAG------ELPMPQST
Rv3825c|M.tuberculosis_H37Rv RRNLSFYAVDLGLLSATHPEELRDLLGTVYRLTAAG------ELPMPQST
MMAR_2340|M.marinum_M RRNLSFYGVDLGMLSITHPRLIRELLTTVYQHTAEG------VLPMPQDT
MAV_2370|M.avium_104 RRNLTFYALDLALMSFSHPDRLRGLLRTVYRLTADG------ALPMPEST
MLBr_00139|M.leprae_Br4923 RRGLTFYYLDLALMSVTQPDRVRELLATVFNLTADG------VLTAPECT
MUL_2010|M.ulcerans_Agy99 RRGLTFYYVDLGLMSVIQPERVRELLSTVYNLTAEG------VLSAPECT
MSMEG_4727|M.smegmatis_MC2_155 RRNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADG------TLPLPEIT
MAB_3148c|M.abscessus_ATCC_199 RRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEG------VLPLPEIS
TH_4621|M.thermoresistible__bu RRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADG------VLPMPQST
Mflv_0405|M.gilvum_PYR-GCK RPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDG------AWTPLPAE
Mvan_0269|M.vanbaalenii_PYR-1 RPDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGKADGSSRAEWVPLPAE
* .::: : * : .* : * : .
Mb3855c|M.bovis_AF2122/97 HYPLVEAATAIRVMGNAEHTGKLVLHIPQTGKSLVTLPPEQAQVFRPDGS
Rv3825c|M.tuberculosis_H37Rv HYPLVEAATAIRVMGNAEHTGKLVLHIPQTGKSLVTLPPEQAQVFRPDGS
MMAR_2340|M.marinum_M HYPLAEAATAIRVMGAADHTGKLLLDIPRSGRSAVVLPPEQVPVLRADGS
MAV_2370|M.avium_104 HYPLADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVVPPAQVRAFRSDGA
MLBr_00139|M.leprae_Br4923 HYPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGS
MUL_2010|M.ulcerans_Agy99 HYPLAEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVVPPEQVEVFRGDGS
MSMEG_4727|M.smegmatis_MC2_155 HYPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVVPPEQVPVFRGDGA
MAB_3148c|M.abscessus_ATCC_199 PSPLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPPSHAPAFRRDGA
TH_4621|M.thermoresistible__bu HYPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGA
Mflv_0405|M.gilvum_PYR-GCK VYPLTEARAAFRRMQQARHIGKIVVQIPNPLQP------------QPDRS
Mvan_0269|M.vanbaalenii_PYR-1 IYPLTEARAAFRRMQQARHVGKIVLQMPKPLQP------------RADRS
** :* ::* * * * **:::.:* . : * :
Mb3855c|M.bovis_AF2122/97 YIITGGLGGLGLFLAEKMAAAG----CGRIVLNSRTQPTQKMRETIEAIA
Rv3825c|M.tuberculosis_H37Rv YIITGGLGGLGLFLAEKMAAAG----CGRIVLNSRTQPTQKMRETIEAIA
MMAR_2340|M.marinum_M YIITGGLGGLGLFLAEKMATAG----AGRIVLSSRSAPSQKALETIELIR
MAV_2370|M.avium_104 YIVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALPNPKALATLERIR
MLBr_00139|M.leprae_Br4923 YIITGGLGGLGLFFASKLAEAG----CGRIVLTARSQPNPKARQTIERLC
MUL_2010|M.ulcerans_Agy99 YIITGGLGGLGLFFASKMAAAG----CGRIVLTARSQPNPKSRQAIERLR
MSMEG_4727|M.smegmatis_MC2_155 YVITGGLGGLGLFLAERMAAAG----CGRIVVNSRSAPSTRSSEIIELIR
MAB_3148c|M.abscessus_ATCC_199 YVVTGGLGGLGLFLARKLAAAG----VGRIILNGRSAPKPEALAAIEQIR
TH_4621|M.thermoresistible__bu YIVTGGMGGLGLYLAGEMAAAG----AGCIVLNGRSAPSGEALRTIEQLR
Mflv_0405|M.gilvum_PYR-GCK YLITGGLGAIGLHTAGYLAQLG----AGDIVLTSRRAPDAAAQQAIADIA
Mvan_0269|M.vanbaalenii_PYR-1 YLITGGLGAIGLHTAAYLAQLG----AGDLVLTSRRAPDADARRAIEEIT
*::***:*.:**. * :* * * ::: .* * : :
Mb3855c|M.bovis_AF2122/97 A-MGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDATLA
Rv3825c|M.tuberculosis_H37Rv A-MGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDATLA
MMAR_2340|M.marinum_M S-IGSDVVVECGDIAQPATAARLVANATATNLPLRGVLHAAAVVEDATLA
MAV_2370|M.avium_104 Q-MGADIVVERGDIAEAGTAQRLLDVATATGLPVRGVLHLAAVIEDATLA
MLBr_00139|M.leprae_Br4923 A-AGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLT
MUL_2010|M.ulcerans_Agy99 A-NGADIVVECGNIAEPETADRLVSAATATGLPLRGVLHAAAVVEDATLS
MSMEG_4727|M.smegmatis_MC2_155 A-TGADIVVECGDIAEPDTALRLVAAATQTGLPLRGVLHAAAVVEDATLA
MAB_3148c|M.abscessus_ATCC_199 Q-GGTEIDVALGDIAEPDTAQRLVAAATETGKPVRGVLHAAALVHDATLA
TH_4621|M.thermoresistible__bu A-AGTEVIVECG----XXXRGQPVEVAVPT------ELRHADEHPDRRGA
Mflv_0405|M.gilvum_PYR-GCK DRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLS
Mvan_0269|M.vanbaalenii_PYR-1 ERYKCRVHTFCADVGDESQVAELLARIRAELPPLAGVAHLAGVLDDALLS
: . . : : * * :
Mb3855c|M.bovis_AF2122/97 NITDELLAR-DWAPKVHGAWELHEATSG-----QPLDWFCLFSSAAALTG
Rv3825c|M.tuberculosis_H37Rv NITDELLAR-DWAPKVHGAWELHEATSG-----QPLDWFCLFSSAAALTG
MMAR_2340|M.marinum_M NITDELLDR-DWAPKVYGAWHLHQATTD-----QPLDWFCSFSSAAAMLG
MAV_2370|M.avium_104 NITDELIER-DWAAKVYGAWNLHCALQESG-AEQSLDWFCSFSSAAALVG
MLBr_00139|M.leprae_Br4923 NITDELIDR-DWSPKVYGSWNLHCATIG-----QPLDWFCLFSSGAALLG
MUL_2010|M.ulcerans_Agy99 NITDELIDR-DWSPKVYGSWNLHRASTG-----QPLDWFCLFSSGAALMG
MSMEG_4727|M.smegmatis_MC2_155 NITDELVEH-DWAPKVYGAWNLHQAVQSGGPATSELDWFCAFSSAAALVG
MAB_3148c|M.abscessus_ATCC_199 NITDELIDRGDWRPKVHGAWNLHEATAD-----QPLDWFCSFSSIAALVG
TH_4621|M.thermoresistible__bu QLCDEFARGEQGAQRNQHRTDAGEGQRD------------AHPPGAVGHD
Mflv_0405|M.gilvum_PYR-GCK QQSVERFRT-ALAPKAFGAVHLDRLTRV-----DDLDFFLVSSSVSSLFG
Mvan_0269|M.vanbaalenii_PYR-1 QQSLERFRT-TLAPKAFGACHLDRLTAG-----DDLDFFIMSSSVSSLFG
: * : . .. : .
Mb3855c|M.bovis_AF2122/97 SPGQSAYSAANSWLDAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPA
Rv3825c|M.tuberculosis_H37Rv SPGQSAYSAANSWLDAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPA
MMAR_2340|M.marinum_M SPGQGAYAAANSWLDAFTHWRHNQNQPATAIAWGPWAEIG----------
MAV_2370|M.avium_104 SPGQGAYAAANSWLDAFTRWRRARGLKATAIAWGAWAQIG----------
MLBr_00139|M.leprae_Br4923 SPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVG----------
MUL_2010|M.ulcerans_Agy99 SPGQGAYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGEVG----------
MSMEG_4727|M.smegmatis_MC2_155 SPGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGEIG----------
MAB_3148c|M.abscessus_ATCC_199 SPGQGAYAAANSWLDGFTHWRRAQGLPATVIAWGAWSEIG----------
TH_4621|M.thermoresistible__bu QPDPGALSDTG--LDERGGQFPGVGVQIPVADPGVGIDHR----------
Mflv_0405|M.gilvum_PYR-GCK SPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARGG-------MAS
Mvan_0269|M.vanbaalenii_PYR-1 SPGQANYATANALLDGLTAHRRARGLPATGVNFGPWAQGG-------MAS
.*. . : :. :* . *
Mb3855c|M.bovis_AF2122/97 RASALEESNYTAITPDEGAYAFEALLRHNRVYTGYAPVIGAPWLVAFAER
Rv3825c|M.tuberculosis_H37Rv RASALEESNYTAITPDEGAYAFEALLRHNRVYTGYAPVIGAPWLVAFAER
MMAR_2340|M.marinum_M RAIALAESSDAAIAPDEGAYAFQTLLRHNRTYTGYAPIIGAPWVTAFAER
MAV_2370|M.avium_104 RGAALADSADVAITPDEGAYAFEALLRHDRACTGYAPITGTPWLTAFAQR
MLBr_00139|M.leprae_Br4923 RATFLAEGGEIMITPDEGAYAFEMLVRYDRPYSGYIPILGAPWLPDLVRR
MUL_2010|M.ulcerans_Agy99 RATFLAEGGEIMIAPDEGMYAFEQMLRHARTYTGYIPIIGAPWLADLVRR
MSMEG_4727|M.smegmatis_MC2_155 RGTAMAE-GDNAIAPDEGAYAFEAILRHDRVYNGYAPVLGASWLTAFAQR
MAB_3148c|M.abscessus_ATCC_199 QGTHLAQNAEAAILPDEGAYAFDTVLRHNRAYTAYAPMAGISWLADFVER
TH_4621|M.thermoresistible__bu -GAVRVDSGVPAQQGVDG-----EVVRHRTLSS---------------VR
Mflv_0405|M.gilvum_PYR-GCK SEAAAANISAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVL
Mvan_0269|M.vanbaalenii_PYR-1 SEAATANIGAQGLVPLEPSAALGALAEVLANGTGQAAVLKANWQRAAKVL
: : : . .
Mb3855c|M.bovis_AF2122/97 SRFFE-----VFSSSN--GSGTSKFRVELNELPRDEWPARLRQLVAEQVS
Rv3825c|M.tuberculosis_H37Rv SRFFE-----VFSSSN--GSGTSKFRVELNELPRDEWPARLRQLVAEQVS
MMAR_2340|M.marinum_M SKFAE-----AFKALEQGRSGSSKFRSELDALPLDEWPGQLRRMVAEQVS
MAV_2370|M.avium_104 SPFAE-----AFRANGQSATGTSKLRAELEELPPEEWSTRLRRLISDQVS
MLBr_00139|M.leprae_Br4923 SPWAE-----MFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQAS
MUL_2010|M.ulcerans_Agy99 SPWAE-----MFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIAEQAS
MSMEG_4727|M.smegmatis_MC2_155 SPFAE-----LFLADTQGASETRKLRSELAALPREEWPTHLRRLIAEQVG
MAB_3148c|M.abscessus_ATCC_199 SPFAQ-----AFRDAGQNQTETNKFLDELRALPREEWPTRLRKLVAEQVG
TH_4621|M.thermoresistible__bu SGRSS-----RWTAPGSRCGSGRRYGGES---------------------
Mflv_0405|M.gilvum_PYR-GCK GSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQ
Mvan_0269|M.vanbaalenii_PYR-1 GSSRPPILDLVLPRPEGEVAGDSELLRQLQEIPVAQRAGFVTEFLQREVQ
. . :
Mb3855c|M.bovis_AF2122/97 LILRRTVDPDRP--LPEYGLDSLGALELRTRIETETG--IRLAPKNVSA-
Rv3825c|M.tuberculosis_H37Rv LILRRTVDPDRP--LPEYGLDSLGALELRTRIETETG--IRLAPKNVSA-
MMAR_2340|M.marinum_M LILRRTIDPDRQ--LSEYGLDSLGNLELRTRVQSETG--IRISSTDIT--
MAV_2370|M.avium_104 LILRRNVDPDRP--LPEYGLDSLGGLELLTRIQTETG--IRVSPADIAAI
MLBr_00139|M.leprae_Br4923 VILRRTIDADRS--FIEYGLDSLGMLEMRTHIESETG--IRLTPKVIATN
MUL_2010|M.ulcerans_Agy99 VILRRTVDADRP--FVEYGLDSLGMLEMRTHIETETG--VRLSPKVIASH
MSMEG_4727|M.smegmatis_MC2_155 LLLRRTVDPDRP--LSEYGLDSLGHLELRTRIETETG--VRVSAMDMT--
MAB_3148c|M.abscessus_ATCC_199 LVLRRSIDPDRS--LPDYGLDSLGNLEIRTRIQADTG--VRIGPADVS--
TH_4621|M.thermoresistible__bu --CRRTTGP------------AAGAAARRGRTRRRRR--PRRPP------
Mflv_0405|M.gilvum_PYR-GCK NFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDY
Mvan_0269|M.vanbaalenii_PYR-1 NFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDY
* . : : . .
Mb3855c|M.bovis_AF2122/97 -TVRGLADHLYEQLAPDDAPAAALSSQ------------------
Rv3825c|M.tuberculosis_H37Rv -TVRGLADHLYEQLAPDDAPAAALSSQ------------------
MMAR_2340|M.marinum_M -TVRGLADHLFAQLAPEEAAASSQ---------------------
MAV_2370|M.avium_104 GTIRGLADLLRDKLTPAGAAQAERV--------------------
MLBr_00139|M.leprae_Br4923 NTARALAQYLADTLAEEEGVAAPAAMVSPETP-------------
MUL_2010|M.ulcerans_Agy99 NTARALSQHLADTLAEEEAQPAAS---------------------
MSMEG_4727|M.smegmatis_MC2_155 -TIRGLAQRLCEMLDTDDAVSAPS---------------------
MAB_3148c|M.abscessus_ATCC_199 -TVRSLAAHIYDRLAEQESEVASS---------------------
TH_4621|M.thermoresistible__bu ----PPPDRVRHRAGPAHGPVRR----------------------
Mflv_0405|M.gilvum_PYR-GCK PTIGGLAEYLVAQLPD-----AETPQAAPQSESEPGPDVTE----
Mvan_0269|M.vanbaalenii_PYR-1 PTIGGLAEYLVGQLPDSDAAAGETPATETSPIDHNHPDREADSPG
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