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MVTGLQTRLLTELEPVVEENLERHLRAVRPWAPHDYVPWSRGRDFAFLGGEDWKPEDSPLDPVAQAALVV NLLTEDNLPSYHREIATRFGRDGAWGTWVGQWTAEEGRHSIALRDYLVVTRGVDPGNLEAMRMAHTVAGY DSGDKTPLEALAYVSFQELATRISHRNTGKASGCPIADQLLARVALDENLHMVFYRNLMLAALDIEPDAA MQAICKEIVGFAMPGMGMEGFAQNAIAIAKAGIYDLRIHHDDVLQPILRFWRVFERADIGPEGEQARDTL AKFLAAVDERAKYYEEKAASRAAAQV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2157 | - | - | 100% (306) | acyl- |
| M. abscessus ATCC 19977 | MAB_4403c | - | 9e-97 | 56.76% (296) | acyl- |
| M. abscessus ATCC 19977 | MAB_2550c | - | 5e-95 | 53.16% (316) | fatty acid desaturase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0847c | desA1 | 7e-89 | 54.96% (282) | acyl- |
| M. gilvum PYR-GCK | Mflv_1668 | - | 2e-90 | 52.35% (298) | fatty acid desaturase, type 2 |
| M. tuberculosis H37Rv | Rv0824c | desA1 | 8e-89 | 54.96% (282) | acyl- |
| M. leprae Br4923 | MLBr_02185 | desA1 | 6e-88 | 51.69% (296) | acyl- |
| M. marinum M | MMAR_4856 | desA1 | 3e-88 | 52.70% (296) | acyl- |
| M. avium 104 | MAV_1793 | - | 2e-87 | 52.15% (303) | Fatty acid desaturase |
| M. smegmatis MC2 155 | MSMEG_5773 | - | 2e-91 | 53.04% (296) | fatty acid desaturase |
| M. thermoresistible (build 8) | TH_1577 | - | 1e-88 | 51.86% (295) | fatty acid desaturase |
| M. ulcerans Agy99 | MUL_0445 | desA1 | 8e-88 | 52.70% (296) | acyl- |
| M. vanbaalenii PYR-1 | Mvan_5927 | - | 1e-138 | 79.11% (292) | fatty acid desaturase, type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0847c|M.bovis_AF2122/97 MS-AKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
Rv0824c|M.tuberculosis_H37Rv MS-AKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
MMAR_4856|M.marinum_M MS-APLTDLHLLHELEPVVEKYLNRHLSMHKNWNPHDYIPWSDGKNYYAL
MUL_0445|M.ulcerans_Agy99 MS-APLTDLHLLHELEPVVEKYLNRHLSIHKNWNPHDYIPWSDGKNYYAL
MLBr_02185|M.leprae_Br4923 MS-AELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYAL
MAV_1793|M.avium_104 MP-KDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTR
Mflv_1668|M.gilvum_PYR-GCK MS-KDLTDLQLLTELEPVVEPLVNRHMRMKKDWNPHDYIPWSDGKNYYAL
MSMEG_5773|M.smegmatis_MC2_155 MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYAL
TH_1577|M.thermoresistible__bu MH-ENLTDLHLLRELEPVVEKLLNRHLSMSKDWNPHDYIPWSDGKNYYAL
MAB_2157|M.abscessus_ATCC_1997 --MVTGLQTRLLTELEPVVEENLERHLRAVRPWAPHDYVPWSRGRDFAFL
Mvan_5927|M.vanbaalenii_PYR-1 --MDT--QASVLHELEPVVAQNLDRHLSMAKEWFPHDYVPWSRGRDFAFL
: :* ****** ::** : * ****:*** *:::
Mb0847c|M.bovis_AF2122/97 GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Rv0824c|M.tuberculosis_H37Rv GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MMAR_4856|M.marinum_M GGQEWDPEQSKLSDVAQIAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MUL_0445|M.ulcerans_Agy99 GGQEWDPEQSKLSDVAQIAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MLBr_02185|M.leprae_Br4923 GGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQW
MAV_1793|M.avium_104 GGQDWEPGQTRLPDVAQVAIVQNLLTEDNLPSYHREIAMNFGMDGPWGQW
Mflv_1668|M.gilvum_PYR-GCK GGQDWDPEQSQLSDVARVAMLVNLLTEDNLPSYHREIAMNFSMDGPWGFW
MSMEG_5773|M.smegmatis_MC2_155 GGQDWDPEQSKLSEVARTAMVQNLLTEDNLPSYHREIAMNMGMDGAWGQW
TH_1577|M.thermoresistible__bu GGQDWYPEEAKLSEVAQTAMVQNLLTEDNLPAYHREIAMNLGMDGAWGQW
MAB_2157|M.abscessus_ATCC_1997 GGEDWKPEDSPLDPVAQAALVVNLLTEDNLPSYHREIATRFGRDGAWGTW
Mvan_5927|M.vanbaalenii_PYR-1 GGEDWHPEDSPLDPVAKVALTVNLLTEDNLPSYHREIATRFSRDGAWGTW
**::* * :: * **: *: **:******:****** :. **.** *
Mb0847c|M.bovis_AF2122/97 VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
Rv0824c|M.tuberculosis_H37Rv VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MMAR_4856|M.marinum_M VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MUL_0445|M.ulcerans_Agy99 VNRWTAEENRHSIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MLBr_02185|M.leprae_Br4923 VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNH--
MAV_1793|M.avium_104 VNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQ--
Mflv_1668|M.gilvum_PYR-GCK VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRVEQMTRGFSPGQNDQI
MSMEG_5773|M.smegmatis_MC2_155 VNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTRGFSPGQNQ--
TH_1577|M.thermoresistible__bu VNRWTAEENRHGISLRDYLVVTRACDPVELEELRVEQMTRGFSPGQNQ--
MAB_2157|M.abscessus_ATCC_1997 VGQWTAEEGRHSIALRDYLVVTRGVDPGNLEAMRMAHTVAGYDSGDKT--
Mvan_5927|M.vanbaalenii_PYR-1 VGQWTAEEGRHSIALRDYLVVTRGVDPVALERLRMEHTVAGYDAGDRT--
*.:***** **. :********* ** ** :*: *:..*:.
Mb0847c|M.bovis_AF2122/97 QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
Rv0824c|M.tuberculosis_H37Rv QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
MMAR_4856|M.marinum_M QGDYFAESVTDSVIYVSFQELATRVSHRNTGKACNDPIADQLMAKISADE
MUL_0445|M.ulcerans_Agy99 QGDYFAESVTDSVIYVSFQELATRVSHRNTGKACNDLIADQLMAKISADE
MLBr_02185|M.leprae_Br4923 QGGLFADTLFDSILYVTFQELATRVSHRNTGKACNETIADQLLAKISSDE
MAV_1793|M.avium_104 QGDMFAESLFDSVMYVSFQELATRVSHRNTGKVCNDAIAEQLMARVSHDE
Mflv_1668|M.gilvum_PYR-GCK EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPIADQLLQRVSADE
MSMEG_5773|M.smegmatis_MC2_155 QGDLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADE
TH_1577|M.thermoresistible__bu QGDLFAESLFDSVIYVTFQELATRVSHRNTGKACNETVADQLLARISADE
MAB_2157|M.abscessus_ATCC_1997 --------PLEALAYVSFQELATRISHRNTGKASGCPIADQLLARVALDE
Mvan_5927|M.vanbaalenii_PYR-1 --------PLAVLAYVSFQELATRVSHRNTGRASGCPVAEQLLARVAADE
: **:*******:******:.. :*:**: ::: **
Mb0847c|M.bovis_AF2122/97 NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
Rv0824c|M.tuberculosis_H37Rv NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
MMAR_4856|M.marinum_M NLHMIFYRDVSEAAFDLAPNQAMKSLHLILHNFKMPGFQVPEFRRKAVII
MUL_0445|M.ulcerans_Agy99 NLHMIFYRDVSEAAFDLAPNQAMKSLHLILHNFKMPGFQVPEFRRKAVII
MLBr_02185|M.leprae_Br4923 NLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFRRKAVII
MAV_1793|M.avium_104 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
Mflv_1668|M.gilvum_PYR-GCK NLHMIFYRDVSEAGFEIAPDQAMRSLHKVLLNFKMPGYTIPDFRRRAVTI
MSMEG_5773|M.smegmatis_MC2_155 NLHMIFYRDVSAAGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVI
TH_1577|M.thermoresistible__bu NLHMIFYRDVSEAGFEIAPDQAMHSLHRVLRNFKMPGFTVPEFRRKAVVI
MAB_2157|M.abscessus_ATCC_1997 NLHMVFYRNLMLAALDIEPDAAMQAICKEIVGFAMPGMGMEGFAQNAIAI
Mvan_5927|M.vanbaalenii_PYR-1 NLHMVFYRNLMAAALDICPDAAMSAIRDEVINFAMPAQGMGDFARNAITI
****:***:: *.::: *: *: :: : * **. : * :.*: *
Mb0847c|M.bovis_AF2122/97 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
Rv0824c|M.tuberculosis_H37Rv AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
MMAR_4856|M.marinum_M AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKMRDELALLVKELE
MUL_0445|M.ulcerans_Agy99 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKMRDELALLVKELE
MLBr_02185|M.leprae_Br4923 AVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELE
MAV_1793|M.avium_104 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEAARMRDDLGLLVKELQ
Mflv_1668|M.gilvum_PYR-GCK ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARMRDEIGAHVEELQ
MSMEG_5773|M.smegmatis_MC2_155 AVGGVYDPRIHLDDVVMPVLRKWRIFEREDFTGEGARLRDDLGRLVEELE
TH_1577|M.thermoresistible__bu AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGKLVEELE
MAB_2157|M.abscessus_ATCC_1997 AKAGIYDLRIHHDDVLQPILRFWRVFERADIGPEGEQARDTLAKFLAAVD
Mvan_5927|M.vanbaalenii_PYR-1 AKAGIYDLRKHHDEVLSPVLRFWNVFQRRDFGPEGEQAREDLAGFLSLVD
* .*:** * * :::: *:*: *.:::* *: *. : *: :. : ::
Mb0847c|M.bovis_AF2122/97 LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
Rv0824c|M.tuberculosis_H37Rv LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
MMAR_4856|M.marinum_M MSCDKFEESKQRQLDREARTGKRVSAFELHKTAGKLPMSRR
MUL_0445|M.ulcerans_Agy99 MSCDKFEESKQRQLDREARTGKRVSAFELHKTAGKLPMSRR
MLBr_02185|M.leprae_Br4923 AACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
MAV_1793|M.avium_104 DASEKFEESKQRYLEREARRTEKITASKVLQTKGTLTLSRH
Mflv_1668|M.gilvum_PYR-GCK ETVQKFEIAKQRREERLRQMAEKKAAKN-LLVGSSAS----
MSMEG_5773|M.smegmatis_MC2_155 DACDKFEVAKERRLERERKMAEKREMKN-LLVSSSSS----
TH_1577|M.thermoresistible__bu EACEKFEVSKQRRLEREARQAEKAAEKKKSFAASTAS----
MAB_2157|M.abscessus_ATCC_1997 ERAKYYE-------EKAASRAAAQV----------------
Mvan_5927|M.vanbaalenii_PYR-1 ERARFYE-------EKRSLSCGTTAATD-------------
:* ::