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MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYALGGQDWDPEQSKLSEVARTAM VQNLLTEDNLPSYHREIAMNMGMDGAWGQWVNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTR GFSPGQNQQGDLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADENLHMIFYRDVSA AGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVIAVGGVYDPRIHLDDVVMPVLRKWRIFEREDFT GEGARLRDDLGRLVEELEDACDKFEVAKERRLERERKMAEKREMKNLLVSSSSS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5773 | - | - | 100% (334) | fatty acid desaturase |
| M. smegmatis MC2 155 | MSMEG_5248 | - | 6e-40 | 33.33% (258) | acyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0847c | desA1 | 1e-154 | 80.00% (315) | acyl- |
| M. gilvum PYR-GCK | Mflv_1668 | - | 1e-158 | 80.42% (332) | fatty acid desaturase, type 2 |
| M. tuberculosis H37Rv | Rv0824c | desA1 | 1e-154 | 80.00% (315) | acyl- |
| M. leprae Br4923 | MLBr_02185 | desA1 | 1e-152 | 75.93% (324) | acyl- |
| M. abscessus ATCC 19977 | MAB_0754c | - | 1e-142 | 71.87% (327) | fatty acid desaturase |
| M. marinum M | MMAR_4856 | desA1 | 1e-154 | 80.00% (315) | acyl- |
| M. avium 104 | MAV_1793 | - | 1e-153 | 79.18% (317) | Fatty acid desaturase |
| M. thermoresistible (build 8) | TH_1577 | - | 1e-167 | 83.73% (332) | fatty acid desaturase |
| M. ulcerans Agy99 | MUL_3646 | desA1_1 | 1e-155 | 80.13% (317) | acyl- |
| M. vanbaalenii PYR-1 | Mvan_5085 | - | 1e-162 | 83.13% (332) | fatty acid desaturase, type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1668|M.gilvum_PYR-GCK -MSKDLTDLQLLTELEPVVEPLVNRHMRMKKDWNPHDYIPWSDGKNYYAL
Mvan_5085|M.vanbaalenii_PYR-1 -MSKDLTDLQLLTELEPVVEPLINRHMRMTKDWNPHDYIPWSDGKNYYAL
Mb0847c|M.bovis_AF2122/97 -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
Rv0824c|M.tuberculosis_H37Rv -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
MMAR_4856|M.marinum_M -MSAPLTDLHLLHELEPVVEKYLNRHLSMHKNWNPHDYIPWSDGKNYYAL
MLBr_02185|M.leprae_Br4923 -MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYAL
MAV_1793|M.avium_104 -MPKDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTR
MUL_3646|M.ulcerans_Agy99 -MSKEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
TH_1577|M.thermoresistible__bu -MHENLTDLHLLRELEPVVEKLLNRHLSMSKDWNPHDYIPWSDGKNYYAL
MSMEG_5773|M.smegmatis_MC2_155 MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYAL
MAB_0754c|M.abscessus_ATCC_199 MSQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKAL
*:*.** **:**** :.** * ******:***:***: :
Mflv_1668|M.gilvum_PYR-GCK GGQDWDPEQSQLSDVARVAMLVNLLTEDNLPSYHREIAMNFSMDGPWGFW
Mvan_5085|M.vanbaalenii_PYR-1 GGQDWDPEQAKLSEVARVAMMVNLLTEDNLPSYHREIAMNFTMDGPWGFW
Mb0847c|M.bovis_AF2122/97 GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Rv0824c|M.tuberculosis_H37Rv GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MMAR_4856|M.marinum_M GGQEWDPEQSKLSDVAQIAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MLBr_02185|M.leprae_Br4923 GGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQW
MAV_1793|M.avium_104 GGQDWEPGQTRLPDVAQVAIVQNLLTEDNLPSYHREIAMNFGMDGPWGQW
MUL_3646|M.ulcerans_Agy99 DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
TH_1577|M.thermoresistible__bu GGQDWYPEEAKLSEVAQTAMVQNLLTEDNLPAYHREIAMNLGMDGAWGQW
MSMEG_5773|M.smegmatis_MC2_155 GGQDWDPEQSKLSEVARTAMVQNLLTEDNLPSYHREIAMNMGMDGAWGQW
MAB_0754c|M.abscessus_ATCC_199 GGQDWDPEQSKLSEVAKIAMITNLLTEDNLPSYHREIAMNFTMDGPWGTW
.**:* * :::*.:**: *:: **:******:*******.: ***.** *
Mflv_1668|M.gilvum_PYR-GCK VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRVEQMTRGFSPGQNDQI
Mvan_5085|M.vanbaalenii_PYR-1 VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRLEQMTRGFSPGQNEQI
Mb0847c|M.bovis_AF2122/97 VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
Rv0824c|M.tuberculosis_H37Rv VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MMAR_4856|M.marinum_M VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MLBr_02185|M.leprae_Br4923 VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNH--
MAV_1793|M.avium_104 VNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQ--
MUL_3646|M.ulcerans_Agy99 VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQ--
TH_1577|M.thermoresistible__bu VNRWTAEENRHGISLRDYLVVTRACDPVELEELRVEQMTRGFSPGQNQ--
MSMEG_5773|M.smegmatis_MC2_155 VNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTRGFSPGQNQ--
MAB_0754c|M.abscessus_ATCC_199 VNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRVEQMTRGFSPGQNRQG
******** **. ::******** ****** **:* :.********
Mflv_1668|M.gilvum_PYR-GCK EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPIADQLLQRVSADE
Mvan_5085|M.vanbaalenii_PYR-1 EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPVADQLLQRVSADE
Mb0847c|M.bovis_AF2122/97 QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
Rv0824c|M.tuberculosis_H37Rv QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
MMAR_4856|M.marinum_M QGDYFAESVTDSVIYVSFQELATRVSHRNTGKACNDPIADQLMAKISADE
MLBr_02185|M.leprae_Br4923 QGGLFADTLFDSILYVTFQELATRVSHRNTGKACNETIADQLLAKISSDE
MAV_1793|M.avium_104 QGDMFAESLFDSVMYVSFQELATRVSHRNTGKVCNDAIAEQLMARVSHDE
MUL_3646|M.ulcerans_Agy99 QGDLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
TH_1577|M.thermoresistible__bu QGDLFAESLFDSVIYVTFQELATRVSHRNTGKACNETVADQLLARISADE
MSMEG_5773|M.smegmatis_MC2_155 QGDLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADE
MAB_0754c|M.abscessus_ATCC_199 GDELFAESLFDSVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDE
**::: **::**:*******:*******.. :.:*::*: ::* **
Mflv_1668|M.gilvum_PYR-GCK NLHMIFYRDVSEAGFEIAPDQAMRSLHKVLLNFKMPGYTIPDFRRRAVTI
Mvan_5085|M.vanbaalenii_PYR-1 NLHMIFYRDVSEAGFEIAPDQAMKSLHKVLRNFKMPGYTIPDFRRRAVTI
Mb0847c|M.bovis_AF2122/97 NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
Rv0824c|M.tuberculosis_H37Rv NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
MMAR_4856|M.marinum_M NLHMIFYRDVSEAAFDLAPNQAMKSLHLILHNFKMPGFQVPEFRRKAVII
MLBr_02185|M.leprae_Br4923 NLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFRRKAVII
MAV_1793|M.avium_104 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
MUL_3646|M.ulcerans_Agy99 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
TH_1577|M.thermoresistible__bu NLHMIFYRDVSEAGFEIAPDQAMHSLHRVLRNFKMPGFTVPEFRRKAVVI
MSMEG_5773|M.smegmatis_MC2_155 NLHMIFYRDVSAAGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVI
MAB_0754c|M.abscessus_ATCC_199 NLHMIFYRNLVEAGMHIAPDQALKSIHKVLDNFKMPGYTIPGFRRNAVTI
********:: *.:.:.*: *: ::* :* :*:***: :* ***.** *
Mflv_1668|M.gilvum_PYR-GCK ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARMRDEIGAHVEELQ
Mvan_5085|M.vanbaalenii_PYR-1 ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARLRDDLGLLVEELQ
Mb0847c|M.bovis_AF2122/97 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
Rv0824c|M.tuberculosis_H37Rv AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
MMAR_4856|M.marinum_M AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKMRDELALLVKELE
MLBr_02185|M.leprae_Br4923 AVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELE
MAV_1793|M.avium_104 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEAARMRDDLGLLVKELQ
MUL_3646|M.ulcerans_Agy99 AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
TH_1577|M.thermoresistible__bu AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGKLVEELE
MSMEG_5773|M.smegmatis_MC2_155 AVGGVYDPRIHLDDVVMPVLRKWRIFEREDFTGEGARLRDDLGRLVEELE
MAB_0754c|M.abscessus_ATCC_199 ATGGVYDPQSHLDEVVMPVLRKWRIFERDDISSEGEWYREDLDRIIGDLK
* **:** : **:::*****:****:**:*:..*. *::: : :*:
Mflv_1668|M.gilvum_PYR-GCK ETVQKFEIAKQRREERLRQMAEKKAAKNLLVGSSAS-----
Mvan_5085|M.vanbaalenii_PYR-1 EAVDKFEVAKQRREERLRQMAEKKAAKNLLVGSSAS-----
Mb0847c|M.bovis_AF2122/97 LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
Rv0824c|M.tuberculosis_H37Rv LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
MMAR_4856|M.marinum_M MSCDKFEESKQRQLDREARTGKRVSAFELHKTAGKLPMSRR
MLBr_02185|M.leprae_Br4923 AACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
MAV_1793|M.avium_104 DASEKFEESKQRYLEREARRTEKITASKVLQTKGTLTLSRH
MUL_3646|M.ulcerans_Agy99 QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
TH_1577|M.thermoresistible__bu EACEKFEVSKQRRLEREARQAEKAAEKKKSFAASTAS----
MSMEG_5773|M.smegmatis_MC2_155 DACDKFEVAKERRLERERKMAEKREMKNLLVSSSSS-----
MAB_0754c|M.abscessus_ATCC_199 KTSADFEEVKAKYLERQAKRAERQAAKAAREAVSV------
: .*: * : :* : :: .