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M. abscessus ATCC 19977 MAB_4403c (-)

annotation: acyl-
coordinates: 4484039 - 4485007
length: 322

PRELTDIEMLSELEPIAETNLNRHLAVATEWHPHDYVPWDRGRNFAQMGGDDWDPEQSQLSEVARAAMIT
NLLTEDNLPSYHRQAAKYFGLDGAWGTWVGRWTAEENRHGIVIRDYLVVTRGVDPVALERARMEHMTAGF
DATDEEESVHQTDFLLSVAYTTLQELATRVSHRNTGKVCDDPVADRMLQRVAADENLHMIFYRNMCSAAL
DLVPDQALDAIGAVIENFRMPGQGMPNFRRNGVLMAKHGIYDPRQHLDEVVTPNLRKWRIFERNDFSAKG
EARRDQLAAYVEDLKGQVVKFEEQRDRMLAREARKREARAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4403c--100% (322)acyl-
M. abscessus ATCC 19977MAB_2550c-e-11559.63% (322) fatty acid desaturase
M. abscessus ATCC 19977MAB_0754c-e-11459.01% (322) fatty acid desaturase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0847cdesA11e-10856.33% (316) acyl-
M. gilvum PYR-GCKMflv_1668-1e-10956.17% (324) fatty acid desaturase, type 2
M. tuberculosis H37RvRv0824cdesA11e-10856.33% (316) acyl-
M. leprae Br4923MLBr_02185desA11e-10554.23% (319) acyl-
M. marinum MMMAR_4856desA11e-10956.56% (320) acyl-
M. avium 104MAV_1793-1e-10555.17% (319) Fatty acid desaturase
M. smegmatis MC2 155MSMEG_5773-1e-11057.23% (318) fatty acid desaturase
M. thermoresistible (build 8)TH_1577-1e-10755.28% (322) fatty acid desaturase
M. ulcerans Agy99MUL_0445desA11e-10755.94% (320) acyl-
M. vanbaalenii PYR-1Mvan_5085-1e-10855.25% (324) fatty acid desaturase, type 2

CLUSTAL 2.0.9 multiple sequence alignment


Mb0847c|M.bovis_AF2122/97           MS-AKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
Rv0824c|M.tuberculosis_H37Rv        MS-AKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
MMAR_4856|M.marinum_M               MS-APLTDLHLLHELEPVVEKYLNRHLSMHKNWNPHDYIPWSDGKNYYAL
MUL_0445|M.ulcerans_Agy99           MS-APLTDLHLLHELEPVVEKYLNRHLSIHKNWNPHDYIPWSDGKNYYAL
MLBr_02185|M.leprae_Br4923          MS-AELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYAL
MAV_1793|M.avium_104                MP-KDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTR
Mflv_1668|M.gilvum_PYR-GCK          MS-KDLTDLQLLTELEPVVEPLVNRHMRMKKDWNPHDYIPWSDGKNYYAL
Mvan_5085|M.vanbaalenii_PYR-1       MS-KDLTDLQLLTELEPVVEPLINRHMRMTKDWNPHDYIPWSDGKNYYAL
MSMEG_5773|M.smegmatis_MC2_155      MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYAL
TH_1577|M.thermoresistible__bu      MH-ENLTDLHLLRELEPVVEKLLNRHLSMSKDWNPHDYIPWSDGKNYYAL
MAB_4403c|M.abscessus_ATCC_199      MP-RELTDIEMLSELEPIAETNLNRHLAVATEWHPHDYVPWDRGRNFAQM
                                    *     *::.:* ****:.*  ::**    . *:****:**. *:*:   

Mb0847c|M.bovis_AF2122/97           GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Rv0824c|M.tuberculosis_H37Rv        GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MMAR_4856|M.marinum_M               GGQEWDPEQSKLSDVAQIAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MUL_0445|M.ulcerans_Agy99           GGQEWDPEQSKLSDVAQIAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MLBr_02185|M.leprae_Br4923          GGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQW
MAV_1793|M.avium_104                GGQDWEPGQTRLPDVAQVAIVQNLLTEDNLPSYHREIAMNFGMDGPWGQW
Mflv_1668|M.gilvum_PYR-GCK          GGQDWDPEQSQLSDVARVAMLVNLLTEDNLPSYHREIAMNFSMDGPWGFW
Mvan_5085|M.vanbaalenii_PYR-1       GGQDWDPEQAKLSEVARVAMMVNLLTEDNLPSYHREIAMNFTMDGPWGFW
MSMEG_5773|M.smegmatis_MC2_155      GGQDWDPEQSKLSEVARTAMVQNLLTEDNLPSYHREIAMNMGMDGAWGQW
TH_1577|M.thermoresistible__bu      GGQDWYPEEAKLSEVAQTAMVQNLLTEDNLPAYHREIAMNLGMDGAWGQW
MAB_4403c|M.abscessus_ATCC_199      GGDDWDPEQSQLSEVARAAMITNLLTEDNLPSYHRQAAKYFGLDGAWGTW
                                    **::* * :::*.:**: *:: **:******:***: *  : :**.** *

Mb0847c|M.bovis_AF2122/97           VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
Rv0824c|M.tuberculosis_H37Rv        VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MMAR_4856|M.marinum_M               VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MUL_0445|M.ulcerans_Agy99           VNRWTAEENRHSIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MLBr_02185|M.leprae_Br4923          VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNH--
MAV_1793|M.avium_104                VNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQ--
Mflv_1668|M.gilvum_PYR-GCK          VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRVEQMTRGFSPGQNDQI
Mvan_5085|M.vanbaalenii_PYR-1       VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRLEQMTRGFSPGQNEQI
MSMEG_5773|M.smegmatis_MC2_155      VNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTRGFSPGQNQ--
TH_1577|M.thermoresistible__bu      VNRWTAEENRHGISLRDYLVVTRACDPVELEELRVEQMTRGFSPGQNQ--
MAB_4403c|M.abscessus_ATCC_199      VGRWTAEENRHGIVIRDYLVVTRGVDPVALERARMEHMTAGFDATDEE--
                                    *.****** **.  :********  *** **  *:* :. **.. ::.  

Mb0847c|M.bovis_AF2122/97           QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
Rv0824c|M.tuberculosis_H37Rv        QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
MMAR_4856|M.marinum_M               QGDYFAESVTDSVIYVSFQELATRVSHRNTGKACNDPIADQLMAKISADE
MUL_0445|M.ulcerans_Agy99           QGDYFAESVTDSVIYVSFQELATRVSHRNTGKACNDLIADQLMAKISADE
MLBr_02185|M.leprae_Br4923          QGGLFADTLFDSILYVTFQELATRVSHRNTGKACNETIADQLLAKISSDE
MAV_1793|M.avium_104                QGDMFAESLFDSVMYVSFQELATRVSHRNTGKVCNDAIAEQLMARVSHDE
Mflv_1668|M.gilvum_PYR-GCK          EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPIADQLLQRVSADE
Mvan_5085|M.vanbaalenii_PYR-1       EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPVADQLLQRVSADE
MSMEG_5773|M.smegmatis_MC2_155      QGDLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADE
TH_1577|M.thermoresistible__bu      QGDLFAESLFDSVIYVTFQELATRVSHRNTGKACNETVADQLLARISADE
MAB_4403c|M.abscessus_ATCC_199      -ESVHQTDFLLSVAYTTLQELATRVSHRNTGKVCDDPVADRMLQRVAADE
                                        .   .  *: *.::******:*******.*:: :*:::: ::: **

Mb0847c|M.bovis_AF2122/97           NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
Rv0824c|M.tuberculosis_H37Rv        NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
MMAR_4856|M.marinum_M               NLHMIFYRDVSEAAFDLAPNQAMKSLHLILHNFKMPGFQVPEFRRKAVII
MUL_0445|M.ulcerans_Agy99           NLHMIFYRDVSEAAFDLAPNQAMKSLHLILHNFKMPGFQVPEFRRKAVII
MLBr_02185|M.leprae_Br4923          NLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFRRKAVII
MAV_1793|M.avium_104                NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
Mflv_1668|M.gilvum_PYR-GCK          NLHMIFYRDVSEAGFEIAPDQAMRSLHKVLLNFKMPGYTIPDFRRRAVTI
Mvan_5085|M.vanbaalenii_PYR-1       NLHMIFYRDVSEAGFEIAPDQAMKSLHKVLRNFKMPGYTIPDFRRRAVTI
MSMEG_5773|M.smegmatis_MC2_155      NLHMIFYRDVSAAGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVI
TH_1577|M.thermoresistible__bu      NLHMIFYRDVSEAGFEIAPDQAMHSLHRVLRNFKMPGFTVPEFRRKAVVI
MAB_4403c|M.abscessus_ATCC_199      NLHMIFYRNMCSAALDLVPDQALDAIGAVIENFRMPGQGMPNFRRNGVLM
                                    ********::. *.:::.*: *: ::  :: :*:***  :*:***..* :

Mb0847c|M.bovis_AF2122/97           AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
Rv0824c|M.tuberculosis_H37Rv        AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
MMAR_4856|M.marinum_M               AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKMRDELALLVKELE
MUL_0445|M.ulcerans_Agy99           AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKMRDELALLVKELE
MLBr_02185|M.leprae_Br4923          AVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELE
MAV_1793|M.avium_104                AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEAARMRDDLGLLVKELQ
Mflv_1668|M.gilvum_PYR-GCK          ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARMRDEIGAHVEELQ
Mvan_5085|M.vanbaalenii_PYR-1       ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARLRDDLGLLVEELQ
MSMEG_5773|M.smegmatis_MC2_155      AVGGVYDPRIHLDDVVMPVLRKWRIFEREDFTGEGARLRDDLGRLVEELE
TH_1577|M.thermoresistible__bu      AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGKLVEELE
MAB_4403c|M.abscessus_ATCC_199      AKHGIYDPRQHLDEVVTPNLRKWRIFERNDFSAKGEARRDQLAAYVEDLK
                                    *  *:** * **:::* * *:****:**:**..:.   **::.  : :*:

Mb0847c|M.bovis_AF2122/97           LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
Rv0824c|M.tuberculosis_H37Rv        LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
MMAR_4856|M.marinum_M               MSCDKFEESKQRQLDREARTGKRVSAFELHKTAGKLPMSRR
MUL_0445|M.ulcerans_Agy99           MSCDKFEESKQRQLDREARTGKRVSAFELHKTAGKLPMSRR
MLBr_02185|M.leprae_Br4923          AACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
MAV_1793|M.avium_104                DASEKFEESKQRYLEREARRTEKITASKVLQTKGTLTLSRH
Mflv_1668|M.gilvum_PYR-GCK          ETVQKFEIAKQRREERLRQMAEKKAAKN-LLVGSSAS----
Mvan_5085|M.vanbaalenii_PYR-1       EAVDKFEVAKQRREERLRQMAEKKAAKN-LLVGSSAS----
MSMEG_5773|M.smegmatis_MC2_155      DACDKFEVAKERRLERERKMAEKREMKN-LLVSSSSS----
TH_1577|M.thermoresistible__bu      EACEKFEVSKQRRLEREARQAEKAAEKKKSFAASTAS----
MAB_4403c|M.abscessus_ATCC_199      GQVVKFEEQRDRMLAREARKREARAG---------------
                                        ***  ::*   *  :  :