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SAPLTDLHLLHELEPVVEKYLNRHLSIHKNWNPHDYIPWSDGKNYYALGGQEWDPEQSKLSDVAQIAMVQ NLVTEDNLPSYHREIAMNMGMDGAWGQWVNRWTAEENRHSIALRDYLVVTRSVDPVELEKLRLEVVNRGF SPGQNHQGDYFAESVTDSVIYVSFQELATRVSHRNTGKACNDLIADQLMAKISADENLHMIFYRDVSEAA FDLAPNQAMKSLHLILHNFKMPGFQVPEFRRKAVIIAVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGE GAKMRDELALLVKELEMSCDKFEESKQRQLDREARTGKRVSAFELHKTAGKLPMSRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0445 | desA1 | - | 100% (338) | acyl- |
| M. ulcerans Agy99 | MUL_3646 | desA1_1 | e-155 | 77.15% (337) | acyl- |
| M. ulcerans Agy99 | MUL_0187 | desA2 | 2e-38 | 31.82% (264) | acyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0847c | desA1 | 0.0 | 91.42% (338) | acyl- |
| M. gilvum PYR-GCK | Mflv_1668 | - | 1e-139 | 71.34% (328) | fatty acid desaturase, type 2 |
| M. tuberculosis H37Rv | Rv0824c | desA1 | 0.0 | 91.42% (338) | acyl- |
| M. leprae Br4923 | MLBr_02185 | desA1 | 1e-163 | 79.88% (338) | acyl- |
| M. abscessus ATCC 19977 | MAB_0754c | - | 1e-132 | 68.12% (320) | fatty acid desaturase |
| M. marinum M | MMAR_4856 | desA1 | 0.0 | 99.11% (338) | acyl- |
| M. avium 104 | MAV_0772 | - | 1e-169 | 83.53% (340) | Fatty acid desaturase |
| M. smegmatis MC2 155 | MSMEG_5773 | - | 1e-152 | 79.05% (315) | fatty acid desaturase |
| M. thermoresistible (build 8) | TH_1577 | - | 1e-156 | 79.81% (322) | fatty acid desaturase |
| M. vanbaalenii PYR-1 | Mvan_5085 | - | 1e-141 | 71.95% (328) | fatty acid desaturase, type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1668|M.gilvum_PYR-GCK -MSKDLTDLQLLTELEPVVEPLVNRHMRMKKDWNPHDYIPWSDGKNYYAL
Mvan_5085|M.vanbaalenii_PYR-1 -MSKDLTDLQLLTELEPVVEPLINRHMRMTKDWNPHDYIPWSDGKNYYAL
MUL_0445|M.ulcerans_Agy99 -MSAPLTDLHLLHELEPVVEKYLNRHLSIHKNWNPHDYIPWSDGKNYYAL
MMAR_4856|M.marinum_M -MSAPLTDLHLLHELEPVVEKYLNRHLSMHKNWNPHDYIPWSDGKNYYAL
Mb0847c|M.bovis_AF2122/97 -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
Rv0824c|M.tuberculosis_H37Rv -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
MAV_0772|M.avium_104 -MSAELTNLQLLQELEPFVEKYLNRHESMHKNWNPHDYIPWSDGKNFYAL
MLBr_02185|M.leprae_Br4923 -MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYAL
TH_1577|M.thermoresistible__bu -MHENLTDLHLLRELEPVVEKLLNRHLSMSKDWNPHDYIPWSDGKNYYAL
MSMEG_5773|M.smegmatis_MC2_155 MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYAL
MAB_0754c|M.abscessus_ATCC_199 MSQKEFTDLELLHELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKAL
*:*.** ****.** :.** : * ******:***:***: **
Mflv_1668|M.gilvum_PYR-GCK GGQDWDPEQSQLSDVARVAMLVNLLTEDNLPSYHREIAMNFSMDGPWGFW
Mvan_5085|M.vanbaalenii_PYR-1 GGQDWDPEQAKLSEVARVAMMVNLLTEDNLPSYHREIAMNFTMDGPWGFW
MUL_0445|M.ulcerans_Agy99 GGQEWDPEQSKLSDVAQIAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MMAR_4856|M.marinum_M GGQEWDPEQSKLSDVAQIAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Mb0847c|M.bovis_AF2122/97 GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Rv0824c|M.tuberculosis_H37Rv GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MAV_0772|M.avium_104 GGQDWEPGQSKLSDVAQVAMVQNLMTEDNLPSYHREIAMNFGMDGPWGQW
MLBr_02185|M.leprae_Br4923 GGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQW
TH_1577|M.thermoresistible__bu GGQDWYPEEAKLSEVAQTAMVQNLLTEDNLPAYHREIAMNLGMDGAWGQW
MSMEG_5773|M.smegmatis_MC2_155 GGQDWDPEQSKLSEVARTAMVQNLLTEDNLPSYHREIAMNMGMDGAWGQW
MAB_0754c|M.abscessus_ATCC_199 GGQDWDPEQSKLSEVAKIAMITNLLTEDNLPSYHREIAMNFTMDGPWGTW
***:* * :::**:**: **: **:******:*******.: ***.** *
Mflv_1668|M.gilvum_PYR-GCK VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRVEQMTRGFSPGQNDQI
Mvan_5085|M.vanbaalenii_PYR-1 VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRLEQMTRGFSPGQNEQI
MUL_0445|M.ulcerans_Agy99 VNRWTAEENRHSIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQG
MMAR_4856|M.marinum_M VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQG
Mb0847c|M.bovis_AF2122/97 VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQG
Rv0824c|M.tuberculosis_H37Rv VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQG
MAV_0772|M.avium_104 VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQV
MLBr_02185|M.leprae_Br4923 VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQG
TH_1577|M.thermoresistible__bu VNRWTAEENRHGISLRDYLVVTRACDPVELEELRVEQMTRGFSPGQNQQG
MSMEG_5773|M.smegmatis_MC2_155 VNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTRGFSPGQNQQG
MAB_0754c|M.abscessus_ATCC_199 VNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRVEQMTRGFSPGQNRQG
***********.*::******** ****** **:* :.******** *
Mflv_1668|M.gilvum_PYR-GCK EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPIADQLLQRVSADE
Mvan_5085|M.vanbaalenii_PYR-1 EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPVADQLLQRVSADE
MUL_0445|M.ulcerans_Agy99 --DYFAESVTDSVIYVSFQELATRVSHRNTGKACNDLIADQLMAKISADE
MMAR_4856|M.marinum_M --DYFAESVTDSVIYVSFQELATRVSHRNTGKACNDPIADQLMAKISADE
Mb0847c|M.bovis_AF2122/97 --HYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
Rv0824c|M.tuberculosis_H37Rv --HYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
MAV_0772|M.avium_104 REDLFAESLFDSVIYVTFQELATRISHRNTGKACNETIADQMLAKISADE
MLBr_02185|M.leprae_Br4923 --GLFADTLFDSILYVTFQELATRVSHRNTGKACNETIADQLLAKISSDE
TH_1577|M.thermoresistible__bu --DLFAESLFDSVIYVTFQELATRVSHRNTGKACNETVADQLLARISADE
MSMEG_5773|M.smegmatis_MC2_155 --DLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADE
MAB_0754c|M.abscessus_ATCC_199 GDELFAESLFDSVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDE
**::: **::**:*******:********* : :**::: ::*:**
Mflv_1668|M.gilvum_PYR-GCK NLHMIFYRDVSEAGFEIAPDQAMRSLHKVLLNFKMPGYTIPDFRRRAVTI
Mvan_5085|M.vanbaalenii_PYR-1 NLHMIFYRDVSEAGFEIAPDQAMKSLHKVLRNFKMPGYTIPDFRRRAVTI
MUL_0445|M.ulcerans_Agy99 NLHMIFYRDVSEAAFDLAPNQAMKSLHLILHNFKMPGFQVPEFRRKAVII
MMAR_4856|M.marinum_M NLHMIFYRDVSEAAFDLAPNQAMKSLHLILHNFKMPGFQVPEFRRKAVII
Mb0847c|M.bovis_AF2122/97 NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
Rv0824c|M.tuberculosis_H37Rv NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
MAV_0772|M.avium_104 NLHMIFYRDVSEAGFAIAPNQAMKSLHKVLRNFQMPGYQVPEFRRKAVMI
MLBr_02185|M.leprae_Br4923 NLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFRRKAVII
TH_1577|M.thermoresistible__bu NLHMIFYRDVSEAGFEIAPDQAMHSLHRVLRNFKMPGFTVPEFRRKAVVI
MSMEG_5773|M.smegmatis_MC2_155 NLHMIFYRDVSAAGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVI
MAB_0754c|M.abscessus_ATCC_199 NLHMIFYRNLVEAGMHIAPDQALKSIHKVLDNFKMPGYTIPGFRRNAVTI
********:: *.: :.*: *: ::* :* :*:***: :* ***.** *
Mflv_1668|M.gilvum_PYR-GCK ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARMRDEIGAHVEELQ
Mvan_5085|M.vanbaalenii_PYR-1 ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARLRDDLGLLVEELQ
MUL_0445|M.ulcerans_Agy99 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKMRDELALLVKELE
MMAR_4856|M.marinum_M AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKMRDELALLVKELE
Mb0847c|M.bovis_AF2122/97 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
Rv0824c|M.tuberculosis_H37Rv AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
MAV_0772|M.avium_104 AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAAALRDDLALLIKELE
MLBr_02185|M.leprae_Br4923 AVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELE
TH_1577|M.thermoresistible__bu AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGKLVEELE
MSMEG_5773|M.smegmatis_MC2_155 AVGGVYDPRIHLDDVVMPVLRKWRIFEREDFTGEGARLRDDLGRLVEELE
MAB_0754c|M.abscessus_ATCC_199 ATGGVYDPQSHLDEVVMPVLRKWRIFERDDISSEGEWYREDLDRIIGDLK
* ***** : **:::*****:****:**:*:..*. *::: : :*:
Mflv_1668|M.gilvum_PYR-GCK ETVQKFEIAKQRREERLRQMAEKKAAKNLLVGSSAS-----
Mvan_5085|M.vanbaalenii_PYR-1 EAVDKFEVAKQRREERLRQMAEKKAAKNLLVGSSAS-----
MUL_0445|M.ulcerans_Agy99 MSCDKFEESKQRQLDREARTGKRVSAFELHKTAGKLPMSRR
MMAR_4856|M.marinum_M MSCDKFEESKQRQLDREARTGKRVSAFELHKTAGKLPMSRR
Mb0847c|M.bovis_AF2122/97 LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
Rv0824c|M.tuberculosis_H37Rv LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
MAV_0772|M.avium_104 TTCDKFEISKRRQLEREARTGKRTTALELHTTAGTLTMSRR
MLBr_02185|M.leprae_Br4923 AACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
TH_1577|M.thermoresistible__bu EACEKFEVSKQRRLEREARQAEKAAEKKKSFAASTAS----
MSMEG_5773|M.smegmatis_MC2_155 DACDKFEVAKERRLERERKMAEKREMKNLLVSSSSS-----
MAB_0754c|M.abscessus_ATCC_199 KTSADFEEVKAKYLERQAKRAERQAAKAAREAVSV------
: .** * : :* : :: .