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QKDFTDLELLYELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKALGGQDWDPEQSKLSEVAKIAMIT NLLTEDNLPSYHREIAMNFTMDGPWGTWVNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRIAQMTSGF SPGQNRQNIPFSESLFDSVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDENLHMIFYRNMVSAG LEIAPNQAVKAVHKVLDNFTMPGYTIPGFRRNAVTIATGGVYDPQSHLDEVVMPVLRKWRIFERDDITGE GEWYREDLARVVTDLKKTSADFEEVKAKYLERQAKRAERQAAKVLV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2550c | - | - | 100% (327) | fatty acid desaturase |
| M. abscessus ATCC 19977 | MAB_0754c | - | e-178 | 92.00% (325) | fatty acid desaturase |
| M. abscessus ATCC 19977 | MAB_3354 | - | e-171 | 87.12% (326) | acyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0847c | desA1 | 1e-131 | 66.26% (326) | acyl- |
| M. gilvum PYR-GCK | Mflv_1668 | - | 1e-138 | 69.91% (329) | fatty acid desaturase, type 2 |
| M. tuberculosis H37Rv | Rv0824c | desA1 | 1e-131 | 66.26% (326) | acyl- |
| M. leprae Br4923 | MLBr_02185 | desA1 | 1e-131 | 66.05% (324) | acyl- |
| M. marinum M | MMAR_3704 | desA1_1 | 1e-136 | 66.97% (327) | acyl- |
| M. avium 104 | MAV_1793 | - | 1e-134 | 68.31% (325) | Fatty acid desaturase |
| M. smegmatis MC2 155 | MSMEG_5773 | - | 1e-140 | 71.30% (324) | fatty acid desaturase |
| M. thermoresistible (build 8) | TH_1577 | - | 1e-136 | 69.44% (324) | fatty acid desaturase |
| M. ulcerans Agy99 | MUL_3646 | desA1_1 | 1e-136 | 66.97% (327) | acyl- |
| M. vanbaalenii PYR-1 | Mvan_5085 | - | 1e-140 | 71.43% (329) | fatty acid desaturase, type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0847c|M.bovis_AF2122/97 -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
Rv0824c|M.tuberculosis_H37Rv -MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
MLBr_02185|M.leprae_Br4923 -MSAELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYAL
MMAR_3704|M.marinum_M -MSKEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
MUL_3646|M.ulcerans_Agy99 -MSKEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
MAV_1793|M.avium_104 -MPKDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTR
TH_1577|M.thermoresistible__bu -MHENLTDLHLLRELEPVVEKLLNRHLSMSKDWNPHDYIPWSDGKNYYAL
MSMEG_5773|M.smegmatis_MC2_155 MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYAL
Mflv_1668|M.gilvum_PYR-GCK -MSKDLTDLQLLTELEPVVEPLVNRHMRMKKDWNPHDYIPWSDGKNYYAL
Mvan_5085|M.vanbaalenii_PYR-1 -MSKDLTDLQLLTELEPVVEPLINRHMRMTKDWNPHDYIPWSDGKNYYAL
MAB_2550c|M.abscessus_ATCC_199 -MQKDFTDLELLYELEPVVEENVHRHLGVTKDWNPHDYVPWSEGKNYKAL
. *:*.** **:**** :.** * ******:***:***: :
Mb0847c|M.bovis_AF2122/97 GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Rv0824c|M.tuberculosis_H37Rv GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MLBr_02185|M.leprae_Br4923 GGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQW
MMAR_3704|M.marinum_M DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
MUL_3646|M.ulcerans_Agy99 DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
MAV_1793|M.avium_104 GGQDWEPGQTRLPDVAQVAIVQNLLTEDNLPSYHREIAMNFGMDGPWGQW
TH_1577|M.thermoresistible__bu GGQDWYPEEAKLSEVAQTAMVQNLLTEDNLPAYHREIAMNLGMDGAWGQW
MSMEG_5773|M.smegmatis_MC2_155 GGQDWDPEQSKLSEVARTAMVQNLLTEDNLPSYHREIAMNMGMDGAWGQW
Mflv_1668|M.gilvum_PYR-GCK GGQDWDPEQSQLSDVARVAMLVNLLTEDNLPSYHREIAMNFSMDGPWGFW
Mvan_5085|M.vanbaalenii_PYR-1 GGQDWDPEQAKLSEVARVAMMVNLLTEDNLPSYHREIAMNFTMDGPWGFW
MAB_2550c|M.abscessus_ATCC_199 GGQDWDPEQSKLSEVAKIAMITNLLTEDNLPSYHREIAMNFTMDGPWGTW
.**** * :::*.:**: *:: **:******:*******.: ***.** *
Mb0847c|M.bovis_AF2122/97 VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
Rv0824c|M.tuberculosis_H37Rv VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MLBr_02185|M.leprae_Br4923 VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNH--
MMAR_3704|M.marinum_M VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQ--
MUL_3646|M.ulcerans_Agy99 VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQ--
MAV_1793|M.avium_104 VNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQ--
TH_1577|M.thermoresistible__bu VNRWTAEENRHGISLRDYLVVTRACDPVELEELRVEQMTRGFSPGQNQ--
MSMEG_5773|M.smegmatis_MC2_155 VNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTRGFSPGQNQ--
Mflv_1668|M.gilvum_PYR-GCK VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRVEQMTRGFSPGQNDQI
Mvan_5085|M.vanbaalenii_PYR-1 VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRLEQMTRGFSPGQNEQI
MAB_2550c|M.abscessus_ATCC_199 VNRWTAEENRHGIAIRDYLVVTRSVDPVELEKLRIAQMTSGFSPGQNR--
******** **. ::******** ****** **: :. *******
Mb0847c|M.bovis_AF2122/97 QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
Rv0824c|M.tuberculosis_H37Rv QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
MLBr_02185|M.leprae_Br4923 QGGLFADTLFDSILYVTFQELATRVSHRNTGKACNETIADQLLAKISSDE
MMAR_3704|M.marinum_M QGDLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
MUL_3646|M.ulcerans_Agy99 QGDLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
MAV_1793|M.avium_104 QGDMFAESLFDSVMYVSFQELATRVSHRNTGKVCNDAIAEQLMARVSHDE
TH_1577|M.thermoresistible__bu QGDLFAESLFDSVIYVTFQELATRVSHRNTGKACNETVADQLLARISADE
MSMEG_5773|M.smegmatis_MC2_155 QGDLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADE
Mflv_1668|M.gilvum_PYR-GCK EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPIADQLLQRVSADE
Mvan_5085|M.vanbaalenii_PYR-1 EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPVADQLLQRVSADE
MAB_2550c|M.abscessus_ATCC_199 QNIPFSESLFDSVVYVTFQELATRVSHRNTGKACAEPVADELLKRISTDE
: *:::: **::**:*******:*******.. :.:*::*: ::* **
Mb0847c|M.bovis_AF2122/97 NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
Rv0824c|M.tuberculosis_H37Rv NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
MLBr_02185|M.leprae_Br4923 NLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFRRKAVII
MMAR_3704|M.marinum_M NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
MUL_3646|M.ulcerans_Agy99 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
MAV_1793|M.avium_104 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
TH_1577|M.thermoresistible__bu NLHMIFYRDVSEAGFEIAPDQAMHSLHRVLRNFKMPGFTVPEFRRKAVVI
MSMEG_5773|M.smegmatis_MC2_155 NLHMIFYRDVSAAGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVI
Mflv_1668|M.gilvum_PYR-GCK NLHMIFYRDVSEAGFEIAPDQAMRSLHKVLLNFKMPGYTIPDFRRRAVTI
Mvan_5085|M.vanbaalenii_PYR-1 NLHMIFYRDVSEAGFEIAPDQAMKSLHKVLRNFKMPGYTIPDFRRRAVTI
MAB_2550c|M.abscessus_ATCC_199 NLHMIFYRNMVSAGLEIAPNQAVKAVHKVLDNFTMPGYTIPGFRRNAVTI
********:: *.:::.*: *: ::* :* :* ***: :* ***.** *
Mb0847c|M.bovis_AF2122/97 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
Rv0824c|M.tuberculosis_H37Rv AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
MLBr_02185|M.leprae_Br4923 AVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELE
MMAR_3704|M.marinum_M AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
MUL_3646|M.ulcerans_Agy99 AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
MAV_1793|M.avium_104 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEAARMRDDLGLLVKELQ
TH_1577|M.thermoresistible__bu AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGKLVEELE
MSMEG_5773|M.smegmatis_MC2_155 AVGGVYDPRIHLDDVVMPVLRKWRIFEREDFTGEGARLRDDLGRLVEELE
Mflv_1668|M.gilvum_PYR-GCK ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARMRDEIGAHVEELQ
Mvan_5085|M.vanbaalenii_PYR-1 ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARLRDDLGLLVEELQ
MAB_2550c|M.abscessus_ATCC_199 ATGGVYDPQSHLDEVVMPVLRKWRIFERDDITGEGEWYREDLARVVTDLK
* **:** : **:::*****:****:**:*:.**. *:::. : :*:
Mb0847c|M.bovis_AF2122/97 LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
Rv0824c|M.tuberculosis_H37Rv LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
MLBr_02185|M.leprae_Br4923 AACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
MMAR_3704|M.marinum_M QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
MUL_3646|M.ulcerans_Agy99 QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
MAV_1793|M.avium_104 DASEKFEESKQRYLEREARRTEKITASKVLQTKGTLTLSRH
TH_1577|M.thermoresistible__bu EACEKFEVSKQRRLEREARQAEKAAEKKKSFAASTAS----
MSMEG_5773|M.smegmatis_MC2_155 DACDKFEVAKERRLERERKMAEKREMKNLLVSSSSS-----
Mflv_1668|M.gilvum_PYR-GCK ETVQKFEIAKQRREERLRQMAEKKAAKNLLVGSSAS-----
Mvan_5085|M.vanbaalenii_PYR-1 EAVDKFEVAKQRREERLRQMAEKKAAKNLLVGSSAS-----
MAB_2550c|M.abscessus_ATCC_199 KTSADFEEVKAKYLERQAKRAERQAAKVLV-----------
: .*: * : :* : ::