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DTQASVLHELEPVVAQNLDRHLSMAKEWFPHDYVPWSRGRDFAFLGGEDWHPEDSPLDPVAKVALTVNLL TEDNLPSYHREIATRFSRDGAWGTWVGQWTAEEGRHSIALRDYLVVTRGVDPVALERLRMEHTVAGYDAG DRTPLAVLAYVSFQELATRVSHRNTGRASGCPVAEQLLARVAADENLHMVFYRNLMAAALDICPDAAMSA IRDEVINFAMPAQGMGDFARNAITIAKAGIYDLRKHHDEVLSPVLRFWNVFQRRDFGPEGEQAREDLAGF LSLVDERARFYEEKRSLSCGTTAATD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5927 | - | - | 100% (307) | fatty acid desaturase, type 2 |
| M. vanbaalenii PYR-1 | Mvan_5085 | - | 6e-90 | 52.16% (301) | fatty acid desaturase, type 2 |
| M. vanbaalenii PYR-1 | Mvan_4653 | - | 6e-50 | 40.87% (252) | fatty acid desaturase, type 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0847c | desA1 | 1e-89 | 55.09% (285) | acyl- |
| M. gilvum PYR-GCK | Mflv_1668 | - | 1e-90 | 51.83% (301) | fatty acid desaturase, type 2 |
| M. tuberculosis H37Rv | Rv0824c | desA1 | 2e-89 | 55.09% (285) | acyl- |
| M. leprae Br4923 | MLBr_02185 | desA1 | 4e-87 | 50.50% (299) | acyl- |
| M. abscessus ATCC 19977 | MAB_2157 | - | 1e-138 | 79.11% (292) | acyl- |
| M. marinum M | MMAR_3704 | desA1_1 | 2e-91 | 54.30% (302) | acyl- |
| M. avium 104 | MAV_1793 | - | 5e-89 | 53.31% (302) | Fatty acid desaturase |
| M. smegmatis MC2 155 | MSMEG_5773 | - | 6e-93 | 54.52% (299) | fatty acid desaturase |
| M. thermoresistible (build 8) | TH_1577 | - | 1e-88 | 51.84% (299) | fatty acid desaturase |
| M. ulcerans Agy99 | MUL_3646 | desA1_1 | 1e-91 | 54.30% (302) | acyl- |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3704|M.marinum_M MS-KEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
MUL_3646|M.ulcerans_Agy99 MS-KEMTNLQLLHELQPVVENLLNRHISMFKEWNPHDYVPWSDGKNYYAL
MAV_1793|M.avium_104 MP-KDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTR
Mb0847c|M.bovis_AF2122/97 MS-AKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
Rv0824c|M.tuberculosis_H37Rv MS-AKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYAL
MLBr_02185|M.leprae_Br4923 MS-AELTDLQLLHELEPVVEKYMNRHERLHKNWNPHDYIPWSDGKNFYAL
Mflv_1668|M.gilvum_PYR-GCK MS-KDLTDLQLLTELEPVVEPLVNRHMRMKKDWNPHDYIPWSDGKNYYAL
MSMEG_5773|M.smegmatis_MC2_155 MSTDDYTDLQLLHELEPVVETLIDRHMRMCKDWNPHDYIPWSDGKNYYAL
TH_1577|M.thermoresistible__bu MH-ENLTDLHLLRELEPVVEKLLNRHLSMSKDWNPHDYIPWSDGKNYYAL
Mvan_5927|M.vanbaalenii_PYR-1 --MDT--QASVLHELEPVVAQNLDRHLSMAKEWFPHDYVPWSRGRDFAFL
MAB_2157|M.abscessus_ATCC_1997 --MVTGLQTRLLTELEPVVEENLERHLRAVRPWAPHDYVPWSRGRDFAFL
: :* **:*** ::** : * ****:*** *:::
MMAR_3704|M.marinum_M DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
MUL_3646|M.ulcerans_Agy99 DGQDWEPGQSQLTDVAQVAMVQNLLTEDNLPSYHREIAMNFSMDGPWGQW
MAV_1793|M.avium_104 GGQDWEPGQTRLPDVAQVAIVQNLLTEDNLPSYHREIAMNFGMDGPWGQW
Mb0847c|M.bovis_AF2122/97 GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
Rv0824c|M.tuberculosis_H37Rv GGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQW
MLBr_02185|M.leprae_Br4923 GGQDWDPEQSQLSDVAQVAMVQNLVTEDNLPSYHREIAMTMGMDGAWGQW
Mflv_1668|M.gilvum_PYR-GCK GGQDWDPEQSQLSDVARVAMLVNLLTEDNLPSYHREIAMNFSMDGPWGFW
MSMEG_5773|M.smegmatis_MC2_155 GGQDWDPEQSKLSEVARTAMVQNLLTEDNLPSYHREIAMNMGMDGAWGQW
TH_1577|M.thermoresistible__bu GGQDWYPEEAKLSEVAQTAMVQNLLTEDNLPAYHREIAMNLGMDGAWGQW
Mvan_5927|M.vanbaalenii_PYR-1 GGEDWHPEDSPLDPVAKVALTVNLLTEDNLPSYHREIATRFSRDGAWGTW
MAB_2157|M.abscessus_ATCC_1997 GGEDWKPEDSPLDPVAQAALVVNLLTEDNLPSYHREIATRFGRDGAWGTW
.*:** * :: * **:.*: **:******:****** :. **.** *
MMAR_3704|M.marinum_M VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQ--
MUL_3646|M.ulcerans_Agy99 VNRWTAEENRHSTALRDYLVVTRAVDPVELEKLRLEQMTRGFSPGQNQ--
MAV_1793|M.avium_104 VNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQ--
Mb0847c|M.bovis_AF2122/97 VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
Rv0824c|M.tuberculosis_H37Rv VNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNH--
MLBr_02185|M.leprae_Br4923 VNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNH--
Mflv_1668|M.gilvum_PYR-GCK VNRWTAEENRHGIALRDYLVVTRNVDPVELEMLRVEQMTRGFSPGQNDQI
MSMEG_5773|M.smegmatis_MC2_155 VNRWTAEENRHGIALRDYLVVTRACDPVELEELRVEQVTRGFSPGQNQ--
TH_1577|M.thermoresistible__bu VNRWTAEENRHGISLRDYLVVTRACDPVELEELRVEQMTRGFSPGQNQ--
Mvan_5927|M.vanbaalenii_PYR-1 VGQWTAEEGRHSIALRDYLVVTRGVDPVALERLRMEHTVAGYDAGDRT--
MAB_2157|M.abscessus_ATCC_1997 VGQWTAEEGRHSIALRDYLVVTRGVDPGNLEAMRMAHTVAGYDSGDKT--
*.:***** **. :********* ** ** :*: *:..*:.
MMAR_3704|M.marinum_M QGDLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
MUL_3646|M.ulcerans_Agy99 QGDLFAESVFDSVMYVSFQELATRVSHRNTGKASNDPIAEQLMARVSHDE
MAV_1793|M.avium_104 QGDMFAESLFDSVMYVSFQELATRVSHRNTGKVCNDAIAEQLMARVSHDE
Mb0847c|M.bovis_AF2122/97 QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
Rv0824c|M.tuberculosis_H37Rv QGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADE
MLBr_02185|M.leprae_Br4923 QGGLFADTLFDSILYVTFQELATRVSHRNTGKACNETIADQLLAKISSDE
Mflv_1668|M.gilvum_PYR-GCK EADLFADSLFDSVIYVTFQELATRVSHRNTGKACEEPIADQLLQRVSADE
MSMEG_5773|M.smegmatis_MC2_155 QGDLFAESLFDSVMYVSFQELATRVSHRNTGKACNDPVADQLLQRVSADE
TH_1577|M.thermoresistible__bu QGDLFAESLFDSVIYVTFQELATRVSHRNTGKACNETVADQLLARISADE
Mvan_5927|M.vanbaalenii_PYR-1 --------PLAVLAYVSFQELATRVSHRNTGRASGCPVAEQLLARVAADE
MAB_2157|M.abscessus_ATCC_1997 --------PLEALAYVSFQELATRISHRNTGKASGCPIADQLLARVALDE
: **:*******:******:.. .:*:**: ::: **
MMAR_3704|M.marinum_M NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
MUL_3646|M.ulcerans_Agy99 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
MAV_1793|M.avium_104 NLHMIFYRDVSAAGLDIAPNQAMKSVHRILRNFKMPGFTVPEFRRKAVII
Mb0847c|M.bovis_AF2122/97 NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
Rv0824c|M.tuberculosis_H37Rv NLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVI
MLBr_02185|M.leprae_Br4923 NLHMIFYRDVSEAGIELAPNLAIKALHKILHNFKMPGFLVPEFRRKAVII
Mflv_1668|M.gilvum_PYR-GCK NLHMIFYRDVSEAGFEIAPDQAMRSLHKVLLNFKMPGYTIPDFRRRAVTI
MSMEG_5773|M.smegmatis_MC2_155 NLHMIFYRDVSAAGLDIAPNQAMASLHRVLANFKMPGYTVPDFRRKAVVI
TH_1577|M.thermoresistible__bu NLHMIFYRDVSEAGFEIAPDQAMHSLHRVLRNFKMPGFTVPEFRRKAVVI
Mvan_5927|M.vanbaalenii_PYR-1 NLHMVFYRNLMAAALDICPDAAMSAIRDEVINFAMPAQGMGDFARNAITI
MAB_2157|M.abscessus_ATCC_1997 NLHMVFYRNLMLAALDIEPDAAMQAICKEIVGFAMPGMGMEGFAQNAIAI
****:***:: *.::: *: *: :: : * **. : * :.*: *
MMAR_3704|M.marinum_M AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
MUL_3646|M.ulcerans_Agy99 AVGGIYDPRIHLNEVVMPVLKKWRIFEREDFTGEAAWMRDDLGVLIKELE
MAV_1793|M.avium_104 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEAARMRDDLGLLVKELQ
Mb0847c|M.bovis_AF2122/97 AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
Rv0824c|M.tuberculosis_H37Rv AVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLE
MLBr_02185|M.leprae_Br4923 AVGGVYDIRIHLDEVVMPVLKKWRILEREDFSGEGTRLRDEIGEHLTELE
Mflv_1668|M.gilvum_PYR-GCK ASGGVYDPRIHLEDIVMPVLKKWRIFEREDFNGESARMRDEIGAHVEELQ
MSMEG_5773|M.smegmatis_MC2_155 AVGGVYDPRIHLDDVVMPVLRKWRIFEREDFTGEGARLRDDLGRLVEELE
TH_1577|M.thermoresistible__bu AVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGKLVEELE
Mvan_5927|M.vanbaalenii_PYR-1 AKAGIYDLRKHHDEVLSPVLRFWNVFQRRDFGPEGEQAREDLAGFLSLVD
MAB_2157|M.abscessus_ATCC_1997 AKAGIYDLRIHHDDVLQPILRFWRVFERADIGPEGEQARDTLAKFLAAVD
* .*:** * * :::: *:*: *.:::* *: *. *: :. : ::
MMAR_3704|M.marinum_M QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
MUL_3646|M.ulcerans_Agy99 QAGDKFDESKQRYLEREERRAEKITASRVLKTEGTLTLSRM
MAV_1793|M.avium_104 DASEKFEESKQRYLEREARRTEKITASKVLQTKGTLTLSRH
Mb0847c|M.bovis_AF2122/97 LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
Rv0824c|M.tuberculosis_H37Rv LACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
MLBr_02185|M.leprae_Br4923 AACDKFEVSKQRYIEREARRTEKITARKVLSTEGTLRMSGR
Mflv_1668|M.gilvum_PYR-GCK ETVQKFEIAKQRREERLRQMAEKKAAKN-LLVGSSAS----
MSMEG_5773|M.smegmatis_MC2_155 DACDKFEVAKERRLERERKMAEKREMKN-LLVSSSSS----
TH_1577|M.thermoresistible__bu EACEKFEVSKQRRLEREARQAEKAAEKKKSFAASTAS----
Mvan_5927|M.vanbaalenii_PYR-1 ERARFYE-------EKRSLSCGTTAATD-------------
MAB_2157|M.abscessus_ATCC_1997 ERAKYYE-------EKAASRAAAQV----------------
:: ::