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LPKPDIPIPTWAGRLLHFLPGAQLATRTASQAFVEITFPIAAHFHTVIPFADVMESAAKRYMRREVHDPT TREQLIPRYSLGCKRPSFHNSYLATYNRSNVSLETSGITHIDHASVHSRDGKAHPIDVLILATGFKVMES GNMPTYVLKGRGGLEQATWWDEHRLQAFEGVSVPGFPNHFNIFGPYGYNGSSYFTLIEAQSRHIVRCLRR ARALGANLVEVKKEANDRYFAEVLSRRHRQVFWQPSCSGANSYYFDKHGDVPLRPSTTFETYWRSRTFRL SDYQFENRAEVVGAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2075 | - | - | 100% (295) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4024c | - | 6e-63 | 44.73% (237) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0513 | - | 2e-55 | 38.68% (287) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 1e-105 | 61.59% (289) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 1e-118 | 68.06% (288) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 1e-105 | 61.59% (289) | monoxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3138 | - | 1e-152 | 83.39% (295) | monooxygenase |
| M. avium 104 | MAV_3378 | - | 1e-104 | 62.32% (284) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 2e-44 | 34.49% (287) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_2450 | - | 2e-31 | 29.61% (304) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1793 | - | 1e-93 | 57.49% (287) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 2e-93 | 56.25% (288) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2075|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M ---------------MGSESGQHYEIVIVGAGFSGIGTAISLLKAGFADF
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLLKEGFSDF
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLDRAGFSDY
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLDRAGFSDY
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLDKAGFGDY
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLDKAGLPDY
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLDRVGMSDY
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLKKMSFDDF
TH_2450|M.thermoresistible__bu -------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLRRRGITDI
MAB_2075|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M LIVDDADGVGGTWHWNTYPGIAVDIPSYSYQFSYEMRTSWSRTYAHGDEL
Mflv_4607|M.gilvum_PYR-GCK LIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIEL
Mb1428c|M.bovis_AF2122/97 LVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHEL
Rv1393c|M.tuberculosis_H37Rv LVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHEL
MUL_1793|M.ulcerans_Agy99 LVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGREL
MAV_3378|M.avium_104 RVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGREL
Mvan_2671|M.vanbaalenii_PYR-1 VVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHEL
MSMEG_0816|M.smegmatis_MC2_155 VILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGREI
TH_2450|M.thermoresistible__bu AILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPEI
MAB_2075|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M KAYAERCVEKYGLQNYIRFNTTVDEACFDEGAALWRLSCSSGQ---NLTA
Mflv_4607|M.gilvum_PYR-GCK KNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELTA
Mb1428c|M.bovis_AF2122/97 KAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EITA
Rv1393c|M.tuberculosis_H37Rv KAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EITA
MUL_1793|M.ulcerans_Agy99 RAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLIT
MAV_3378|M.avium_104 KAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVTA
Mvan_2671|M.vanbaalenii_PYR-1 KTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLSA
MSMEG_0816|M.smegmatis_MC2_155 KRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQA
TH_2450|M.thermoresistible__bu HRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRP---PVTA
MAB_2075|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M RFVINCSGVLSRPKWPDIPGVRDFAGVTLHTARWDHTKDLTGKRVAVIGT
Mflv_4607|M.gilvum_PYR-GCK RFVINASGVLTRPKSPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAVIGT
Mb1428c|M.bovis_AF2122/97 RFLISACGILTVPKLPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGIIGT
Rv1393c|M.tuberculosis_H37Rv RFLISACGILTVPKLPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGIIGT
MUL_1793|M.ulcerans_Agy99 RFIINASGVLTVPKLPDIAGVDSFAGVTMHTARWDHSQELTGKRVGIIGT
MAV_3378|M.avium_104 RFLISACGVLTVPNLPDIDGVDSFAGITMHTARWDHGQDLRGKRVAVIGT
Mvan_2671|M.vanbaalenii_PYR-1 RFLVNAGGVLTVPKLPDIAGVDSFAGVTMHTARWDHTQDLRGKRVAIIGT
MSMEG_0816|M.smegmatis_MC2_155 RFLITATGFLSQPHTPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAVVGT
TH_2450|M.thermoresistible__bu RFVISSVGGYVNARATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAVIGT
MAB_2075|M.abscessus_ATCC_1997 ----------------------------MPKPDIPIPTWAGRLLHFLPGA
MMAR_3138|M.marinum_M GASAVQLIPEVAKIASSLTVFQRTPIYCLPKPDFSIPSWAATVMRLVPGA
Mflv_4607|M.gilvum_PYR-GCK GASAVQLIPSIAKDVDTLTVFQRTPIWCLPKFDFAVPRPLSALLRLAPGA
Mb1428c|M.bovis_AF2122/97 GASAVQVIPEMAPIVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMR-IPGG
Rv1393c|M.tuberculosis_H37Rv GASAVQVIPEMAPIVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMR-IPGG
MUL_1793|M.ulcerans_Agy99 GASAVQVIPEIAPIVKHLTVFQRTPIWCFPKFDFPLPAALRWAMR-IPGG
MAV_3378|M.avium_104 GASAVQVIPEIAPIVSSLTVFQRTPIWCFPKLDVPLPAPARWAMR-FPGG
Mvan_2671|M.vanbaalenii_PYR-1 GASAVQVIPEIAPIVERLTVFQRTPIWCFPKFDVPLSKTAQTMMR-LPFG
MSMEG_0816|M.smegmatis_MC2_155 GATAVQLIPELAERVAELTVYQRTPIWVVPKVDVRFPPAVRALFARVPLT
TH_2450|M.thermoresistible__bu GSSGAQIVSALSGRVARLDVYQRTPNWILPRPDFALPRALQRVLELPGVA
.*: *. .. :
MAB_2075|M.abscessus_ATCC_1997 QLATRTASQAFVEITFPIAAHFHTVIP----------FADVMESAAKRYM
MMAR_3138|M.marinum_M QLMTRTASQAFVEFTFPIAAHFHSLIP----------VSDLMEEAAKRYM
Mflv_4607|M.gilvum_PYR-GCK QIAARGASQAFVELTFPVAAHFHTAIP----------LASAIERAAISYM
Mb1428c|M.bovis_AF2122/97 KAVHRLLSQAFVEATFPIAAHYFAVFP----------LAKHMESAGRRYL
Rv1393c|M.tuberculosis_H37Rv KAVHRLLSQAFVEATFPIAAHYFAVFP----------LAKHMESAGRRYL
MUL_1793|M.ulcerans_Agy99 KALQRLLSQAYVEATFPISAHYFTVFP----------LARWSAVLGRRYL
MAV_3378|M.avium_104 KALQRLLSQAYVELTFPISAHYFTVIP----------LAKRMAALGRAYL
Mvan_2671|M.vanbaalenii_PYR-1 KSLQRLISQAFVELTFPLAAQYFTVNP----------MAKRMGAVGRAYL
MSMEG_0816|M.smegmatis_MC2_155 QRVVRAITDAIYAFMVDTAVLKHRYFRR---------LNIAAADLGRLHL
TH_2450|M.thermoresistible__bu AVLHNIGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFAFRVLL
. . . . :
MAB_2075|M.abscessus_ATCC_1997 RREVHDPTTREQLIPRYSLGCKRPSFHNSYLATYNRSNVSLETSGITHID
MMAR_3138|M.marinum_M RRAVDDPVTRDQLIPRYSLGCKRPSFHNSYLATYNRRNVSLETSGITHVD
Mflv_4607|M.gilvum_PYR-GCK RRQVTDPVVREKLTPRYALGCKRPSFHNEYLKTFNRENVLLETNPITRVD
Mb1428c|M.bovis_AF2122/97 RQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKIT
Rv1393c|M.tuberculosis_H37Rv RQQVHDPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKIT
MUL_1793|M.ulcerans_Agy99 RQRVDDPVVRDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEPIEKIT
MAV_3378|M.avium_104 RRQVRDPAVREQLTPRYAVGCKRPGFHNGYLATFNRDNVRLVTEPIDKIT
Mvan_2671|M.vanbaalenii_PYR-1 RKQVDDPVLRDKLTPRYAVGCKRPGFHNTYLSTFNRDNVDLVTEPIDKIT
MSMEG_0816|M.smegmatis_MC2_155 AASIRDPDLRSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADGIDHVE
TH_2450|M.thermoresistible__bu RAVVHDPQTRRRLMPAHGILAKRPIISGSYLPAFNDPRTHLITTPIERIT
: ** * :* * : . .*** : . * ::. .. * : * ::
MAB_2075|M.abscessus_ATCC_1997 HASVHSRDGKAHPIDVLILATGFKVMES----GNMPTYVLKGRGGLEQAT
MMAR_3138|M.marinum_M HASVHTEDGKSYPIDVMVLATGFKVMES----GNMPTYVLKGRGGVEQSA
Mflv_4607|M.gilvum_PYR-GCK ETAVITADGVRHEIDVLVLATGFKVMES----DSMPTYSLRGVAGRDQAQ
Mb1428c|M.bovis_AF2122/97 PTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGGASLSR
Rv1393c|M.tuberculosis_H37Rv PTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGGASLSR
MUL_1793|M.ulcerans_Agy99 PTSVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAGRSLSQ
MAV_3378|M.avium_104 PDAVATTDGETHEIDVLILATGFKVMDP----DSVPTFAVTGSGGRSLSR
Mvan_2671|M.vanbaalenii_PYR-1 GSGVSTTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTGPGGRSLAR
MSMEG_0816|M.smegmatis_MC2_155 PDGIVNADGSKTVIDTLVLATGFDLWEA-----NFPAIEVIGRQGRDLGK
TH_2450|M.thermoresistible__bu AAGVRTTDGVERPVDLIVTATGYELWTDP---ETYFPGTILGDAGFDLAL
.: . ** :* :: ***:.: . : * * . .
MAB_2075|M.abscessus_ATCC_1997 WWDEHRLQAFEGVSVPGFPNHFNIFGPYGYNGSSYFTLIEAQSRHIVRCL
MMAR_3138|M.marinum_M WWDEHRLQAFEGVSVPGFPNHFNIFGPYGYNGSSYFTLIEAQSRHIVRCL
Mflv_4607|M.gilvum_PYR-GCK WWDENRLQAYEGVSVPGFPNHFSVFGPYGYNGSSYFALIEAQAGHILRCL
Mb1428c|M.bovis_AF2122/97 FWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIRCL
Rv1393c|M.tuberculosis_H37Rv FWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAHHIIRCL
MUL_1793|M.ulcerans_Agy99 FWEEHRAQAYQGVSVPGYRNFFAVFGPYGYVGSSYFALIETQTHHILRCL
MAV_3378|M.avium_104 FWDEHRLQAYEGVTVPGFPNLFTVFGPYGYVGSSYFALIEAQTHHIVRCL
Mvan_2671|M.vanbaalenii_PYR-1 FWDDNRLQAYEGVSVPGFPNFFTVFGPYGYVGSSYFALIEAQTRHIVRCL
MSMEG_0816|M.smegmatis_MC2_155 WWRETRFQAYQGVSMPYFPNYLSLAGPYAFLGLNFFNTMEYQMRLMERLL
TH_2450|M.thermoresistible__bu DYRENGLRSYGGTAHPRLPNRWEIVGPLAFVGVGWTDFVETMAEHAVRII
: : ::: *.: * * : ** .: * .: :* * :
MAB_2075|M.abscessus_ATCC_1997 RRARALGANLVEVKKEANDRYFAEVLSR-RHRQVFWQPSCSGANSYYFDK
MMAR_3138|M.marinum_M RRARTLKADYVEVRQQANDRYFGDMVSR-RHRQVFWQPSCSNANSYYFDK
Mflv_4607|M.gilvum_PYR-GCK RHARTADSNYVEVREEANQRFFAEMLAR-RHTQVFWQDSCAGANSYYFDK
Mb1428c|M.bovis_AF2122/97 KRARRTGATRIEVTEEANARYFAEVMRR-RHRQVFWQDSCRLANSYYFDK
Rv1393c|M.tuberculosis_H37Rv KRARRTGATRIEVTEEANARYFAEVMRR-RHRQVFWQDSCRLANSYYFDK
MUL_1793|M.ulcerans_Agy99 KRARRDGATRVEVTEEANARYFAEMMRR-RYRQVFWQDSCRRANSYYFDK
MAV_3378|M.avium_104 KRAQRLGATRVEVSEEANDRYFAEMMRR-RHRQIFWQDSCRLANSYYFDK
Mvan_2671|M.vanbaalenii_PYR-1 DAARRRRATRVEVRREANDRYFAEMMRK-RHRQIFWQDSCQLSNSYYFDQ
MSMEG_0816|M.smegmatis_MC2_155 GEVARRDARTFEVTEEANRRYLDRMTDA-LGDSLFTLGNCASARSYYFNP
TH_2450|M.thermoresistible__bu DAARRRGADVVTVTDEAFGRWDARMRKAGKAARLYYTRCNPGVNTYYVNS
. : . * :* *: : :: .:**.:
MAB_2075|M.abscessus_ATCC_1997 HGDVP-LRPSTTFETYWRSRTFRLSDYQFENR----AEVVGAR-------
MMAR_3138|M.marinum_M HGDVP-LRPSTTLETYWRSRTFRLSDYRFERR----AESVGAR-------
Mflv_4607|M.gilvum_PYR-GCK HGDVP-LRPTTTVESIWRSRRFDLADYRFERRPAKKADTAPQKVDTAG--
Mb1428c|M.bovis_AF2122/97 NGDVP-LRPTTTVEAYWRSRRFDLGDYRISS-------------------
Rv1393c|M.tuberculosis_H37Rv NGDVP-LRPTTTVEAYWRSRRFDLGDYRISS-------------------
MUL_1793|M.ulcerans_Agy99 NGDVP-LRPTTTVEAYWRGRHFDLDDYRFGR-------------------
MAV_3378|M.avium_104 NGDVP-LRPGTTPEVYWRSRRFDLDDYRFTG-------------------
Mvan_2671|M.vanbaalenii_PYR-1 HGDVP-LRPASTPEAYWRSRRFPIDDYEFSC-------------------
MSMEG_0816|M.smegmatis_MC2_155 SGEATLLRPMTTRRAVAEASRFPLSDYTFA--------------------
TH_2450|M.thermoresistible__bu QRDTVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSAVRALRHAEGNE
:. ** : . . : ** :
MAB_2075|M.abscessus_ATCC_1997 --
MMAR_3138|M.marinum_M --
Mflv_4607|M.gilvum_PYR-GCK --
Mb1428c|M.bovis_AF2122/97 --
Rv1393c|M.tuberculosis_H37Rv --
MUL_1793|M.ulcerans_Agy99 --
MAV_3378|M.avium_104 --
Mvan_2671|M.vanbaalenii_PYR-1 --
MSMEG_0816|M.smegmatis_MC2_155 --
TH_2450|M.thermoresistible__bu AV