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MTSARVRDGEARGLRQGVPDHEVVIIGAGFGGIGAGVELTKRGVHDFVILEKWGAAGGTWHANKYPGVAV DIPTFIYSFSYDQKTTWSKFFTPGDELEQYANELVDKHELRGKIRFNTRVVRQDFDESQNIWVLTLEGGG VVTGRHVIAATGGLEQPKLPEIDGIDSYKGVLMHTALWDKDIELAGKRVAVIGTGATSLQMVPEIAPQVG HLTVFQRTPIYVGPKPDWRYNGFWRALFGFPGVAKAIRHAINLSTAYIPDAVFKLDSKYAESVSMALANR IRAWMRTQVDDPVTREKLLPYYGFGCKRPSFSNTYLKTFNRPNVALVTEPIQRITEKGLLTADGVEHEVD VLICATGFAIWDHMPAFPTTGRGGKDLKQFFQTNRYQAYQGVSIPDYPNFFLVLGPYGYVFGPYHMLIES TTTHAARVIAETKKRGATTAEVKQDVHDAYFHKMHERNKNHLWLSPACSTANTYYIDNHGDSPFRPGGFG EMYFHNKYFRLDNYRYGTETIAPAVESAPKRKRNKEVVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0513 | - | - | 100% (529) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4024c | - | e-166 | 54.12% (497) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0140c | - | e-140 | 50.30% (503) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 1e-130 | 46.14% (492) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 1e-120 | 44.01% (509) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 1e-130 | 46.14% (492) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 2e-28 | 24.50% (400) | putative monooxygenase |
| M. marinum M | MMAR_2207 | - | 1e-134 | 47.67% (493) | monoxygenase |
| M. avium 104 | MAV_3378 | - | 1e-135 | 48.28% (493) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 1e-102 | 39.44% (464) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_2450 | - | 8e-79 | 33.97% (527) | PUTATIVE putative FAD dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_1793 | - | 1e-129 | 47.13% (488) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 1e-129 | 47.39% (498) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLDRAG-FSD
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLDRAG-FSD
MMAR_2207|M.marinum_M -----------------MSIEPDYQIVIVGAGFSGIGAAISLDKAG-FGD
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLDKAG-FGD
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLDKAG-LPD
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLDRVG-MSD
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLLKEG-FSD
MAB_0513|M.abscessus_ATCC_1997 ---MTSARVRDGEARGLRQGVPDHEVVIIGAGFGGIGAGVELTKRG-VHD
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLKKMS-FDD
TH_2450|M.thermoresistible__bu -------------MTVTGDVRPEYDVAIIGAGPGGIAAAHKLRRRG-ITD
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
::*** .*:... * .
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MMAR_2207|M.marinum_M YLVIEAGDGVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MAV_3378|M.avium_104 YRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRE
Mvan_2671|M.vanbaalenii_PYR-1 YVVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHE
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
MAB_0513|M.abscessus_ATCC_1997 FVILEKWGAAGGTWHANKYPGVAVDIPTFIYSFSYDQKTTWSKFFTPGDE
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
TH_2450|M.thermoresistible__bu IAILERGDDFGGTWRDNHYPGLAVDIPILWYQFSFNRNPRWSRVFAPGPE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
::: **** ***: * : : .: : *
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
MMAR_2207|M.marinum_M LRAYAEHCADKYGIRPRIRFNTKVLGAEFDDERSLWRLQTDPGG---ELT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLI
MAV_3378|M.avium_104 LKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVT
Mvan_2671|M.vanbaalenii_PYR-1 LKTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLS
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELT
MAB_0513|M.abscessus_ATCC_1997 LEQYANELVDKHELRGKIRFNTRVVRQDFDESQNIWVLTLEGGG---VVT
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQ
TH_2450|M.thermoresistible__bu IHRYLTDTARSLGLYPLLRPHHDVVGQRWNAENAMWQLTVRDRP---PVT
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
: * . : :* * . * : :
Mb1428c|M.bovis_AF2122/97 ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MMAR_2207|M.marinum_M TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MAV_3378|M.avium_104 ARFLISACGVLTVPN--LPDIDGVDSFAGITMHTARWDHGQDLRGKRVAV
Mvan_2671|M.vanbaalenii_PYR-1 ARFLVNAGGVLTVPK--LPDIAGVDSFAGVTMHTARWDHTQDLRGKRVAI
Mflv_4607|M.gilvum_PYR-GCK ARFVINASGVLTRPK--SPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
MAB_0513|M.abscessus_ATCC_1997 GRHVIAATGGLEQPK--LPEIDGIDSYKGVLMHTALWDKDIELAGKRVAV
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAV
TH_2450|M.thermoresistible__bu ARFVISSVGGYVNAR--ATDLEGLSDFTGKVLRPNCWDDGYDTRDKRVAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
.:. . * . . : * .: * ::. * . :. :
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAP-IVSHLTVFQRTPIWCFPKFDVPLPTAVRWAMRI
MMAR_2207|M.marinum_M IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAP-IVKHLTVFQRTPIWCFPKFDFPLPAALRWAMRI
MAV_3378|M.avium_104 IGTGASAVQVIPEIAP-IVSSLTVFQRTPIWCFPKLDVPLPAPARWAMRF
Mvan_2671|M.vanbaalenii_PYR-1 IGTGASAVQVIPEIAP-IVERLTVFQRTPIWCFPKFDVPLSKTAQTMMRL
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAK-DVDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
MAB_0513|M.abscessus_ATCC_1997 IGTGATSLQMVPEIAP-QVGHLTVFQRTPIYVGPKPDWRYNGFWRALFGF
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAE-RVAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
TH_2450|M.thermoresistible__bu IGTGSSGAQIVSALSG-RVARLDVYQRTPNWILPRPDFALPRALQRVLEL
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLP
:*:*::. ::. :: . : : **:* : .:
Mb1428c|M.bovis_AF2122/97 P-GGKAVHRLL--SQAFV-EATFPIAAHYFAVFPLAKHMESAG-------
Rv1393c|M.tuberculosis_H37Rv P-GGKAVHRLL--SQAFV-EATFPIAAHYFAVFPLAKHMESAG-------
MMAR_2207|M.marinum_M P-GGKALQRLL--SQAYV-EATFPISAHYFTVFPLARWSAVLG-------
MUL_1793|M.ulcerans_Agy99 P-GGKALQRLL--SQAYV-EATFPISAHYFTVFPLARWSAVLG-------
MAV_3378|M.avium_104 P-GGKALQRLL--SQAYV-ELTFPISAHYFTVIPLAKRMAALG-------
Mvan_2671|M.vanbaalenii_PYR-1 P-FGKSLQRLI--SQAFV-ELTFPLAAQYFTVNPMAKRMGAVG-------
Mflv_4607|M.gilvum_PYR-GCK APGAQIAARGA--SQAFV-ELTFPVAAHFHTAIPLASAIERAA-------
MAB_0513|M.abscessus_ATCC_1997 PGVAKAIRHAINLSTAYIPDAVFKLDSKYAESVSMA--LANRI-------
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVRAITDAIYAFMVDTAVLKHRYFRRLNIA--AADLG-------
TH_2450|M.thermoresistible__bu PGVAAVLHNIGRAVFDLFFVVPIVHLMAHVPDRVLVRLLRGYDSLARFAF
MLBr_00065|M.leprae_Br4923 DKYAYTAVRWKN---------ILRQSALYGACQKWPQRMRNILLG-----
. .
Mb1428c|M.bovis_AF2122/97 RRYLRQQVHDPVVREQLTPRYAVGCKRPGFHN--TYLSTFNRDNVRLVTE
Rv1393c|M.tuberculosis_H37Rv RRYLRQQVHDPVVREQLTPRYAVGCKRPGFHN--TYLSTFNRDNVRLVTE
MMAR_2207|M.marinum_M RRYLRQRVNDPVVRDQLTPRYAVGCKRPGFHN--GYLSTFNRDNVQLVTE
MUL_1793|M.ulcerans_Agy99 RRYLRQRVDDPVVRDQLTPRYAVDCKRPGFHN--GYLSTFNRDNVQLVTE
MAV_3378|M.avium_104 RAYLRRQVRDPAVREQLTPRYAVGCKRPGFHN--GYLATFNRDNVRLVTE
Mvan_2671|M.vanbaalenii_PYR-1 RAYLRKQVDDPVLRDKLTPRYAVGCKRPGFHN--TYLSTFNRDNVDLVTE
Mflv_4607|M.gilvum_PYR-GCK ISYMRRQVTDPVVREKLTPRYALGCKRPSFHN--EYLKTFNRENVLLETN
MAB_0513|M.abscessus_ATCC_1997 RAWMRTQVDDPVTREKLLPYYGFGCKRPSFSN--TYLKTFNRPNVALVTE
MSMEG_0816|M.smegmatis_MC2_155 RLHLAASIRDPDLRSKLTPDYDFGCKRPTFSN--SYYRTFTKPHVHLQAD
TH_2450|M.thermoresistible__bu RVLLRAVVHDPQTRRRLMPAHGILAKRPIISG--SYLPAFNDPRTHLITT
MLBr_00065|M.leprae_Br4923 -HVARRLPKGYDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTD
. : :: * : :* : :: . : :
Mb1428c|M.bovis_AF2122/97 PIDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTG
Rv1393c|M.tuberculosis_H37Rv PIDKITPTAVATTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTG
MMAR_2207|M.marinum_M PIEKITPTAVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRA
MUL_1793|M.ulcerans_Agy99 PIEKITPTSVATDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRA
MAV_3378|M.avium_104 PIDKITPDAVATTDGETHEIDVLILATGFKVMDP----DSVPTFAVTGSG
Mvan_2671|M.vanbaalenii_PYR-1 PIDKITGSGVSTTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTGPG
Mflv_4607|M.gilvum_PYR-GCK PITRVDETAVITADGVRHEIDVLVLATGFKVMES----DSMPTYSLRGVA
MAB_0513|M.abscessus_ATCC_1997 PIQRITEKGLLTADGVEHEVDVLICATGFAIWDH------MPAFPTTGRG
MSMEG_0816|M.smegmatis_MC2_155 GIDHVEPDGIVNADGSKTVIDTLVLATGFDLWEAN-----FPAIEVIGRQ
TH_2450|M.thermoresistible__bu PIERITAAGVRTTDGVERPVDLIVTATGYELWTDP---ETYFPGTILGDA
MLBr_00065|M.leprae_Br4923 AIDRFTSTGIRLKSGNELRADIIVTATGLNLQLFG------------GAV
* :. .: .* * :: *** : *
Mb1428c|M.bovis_AF2122/97 GASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAH
Rv1393c|M.tuberculosis_H37Rv GASLSRFWDEHRLQAYEGVSVPGYPNFFTVFGPYGYVGSSYFALIETQAH
MMAR_2207|M.marinum_M GRSLSQFWEEHRAQAYQGVSVPGYPNFFAVFGPYGYVGSSYFALIETQTH
MUL_1793|M.ulcerans_Agy99 GRSLSQFWEEHRAQAYQGVSVPGYRNFFAVFGPYGYVGSSYFALIETQTH
MAV_3378|M.avium_104 GRSLSRFWDEHRLQAYEGVTVPGFPNLFTVFGPYGYVGSSYFALIEAQTH
Mvan_2671|M.vanbaalenii_PYR-1 GRSLARFWDDNRLQAYEGVSVPGFPNFFTVFGPYGYVGSSYFALIEAQTR
Mflv_4607|M.gilvum_PYR-GCK GRDQAQWWDENRLQAYEGVSVPGFPNHFSVFGPYGYNGSSYFALIEAQAG
MAB_0513|M.abscessus_ATCC_1997 GKDLKQFFQTNRYQAYQGVSIPDYPNFFLVLGPYGYVFGPYHMLIESTTT
MSMEG_0816|M.smegmatis_MC2_155 GRDLGKWWRETRFQAYQGVSMPYFPNYLSLAGPYAFLGLNFFNTMEYQMR
TH_2450|M.thermoresistible__bu GFDLALDYRENGLRSYGGTAHPRLPNRWEIVGPLAFVGVGWTDFVETMAE
MLBr_00065|M.leprae_Br4923 ATVDGQPVDLAQTMSYKGMMLSGLPNMIYTVG---YTNASWTLKADLVSE
. :* * . * * : : :
Mb1428c|M.bovis_AF2122/97 HIIRCLKRARRTGATRIEVT---EEANARYFAEVMRR-RHRQVFWQDSCR
Rv1393c|M.tuberculosis_H37Rv HIIRCLKRARRTGATRIEVT---EEANARYFAEVMRR-RHRQVFWQDSCR
MMAR_2207|M.marinum_M HILRCLKRARRDGATRVEVT---EEANARYFAEMMRR-RYRQVFWQDSCR
MUL_1793|M.ulcerans_Agy99 HILRCLKRARRDGATRVEVT---EEANARYFAEMMRR-RYRQVFWQDSCR
MAV_3378|M.avium_104 HIVRCLKRAQRLGATRVEVS---EEANDRYFAEMMRR-RHRQIFWQDSCR
Mvan_2671|M.vanbaalenii_PYR-1 HIVRCLDAARRRRATRVEVR---REANDRYFAEMMRK-RHRQIFWQDSCQ
Mflv_4607|M.gilvum_PYR-GCK HILRCLRHARTADSNYVEVR---EEANQRFFAEMLAR-RHTQVFWQDSCA
MAB_0513|M.abscessus_ATCC_1997 HAARVIAETKKRGATTAEVK---QDVHDAYFHKMHER-NKNHLWLSPACS
MSMEG_0816|M.smegmatis_MC2_155 LMERLLGEVARRDARTFEVT---EEANRRYLDRMTDA-LGDSLFTLGNCA
TH_2450|M.thermoresistible__bu HAVRIIDAARRRGADVVTVT---DEAFGRWDARMRKAGKAARLYYTRCNP
MLBr_00065|M.leprae_Br4923 FFCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQG
* : * :. . :
Mb1428c|M.bovis_AF2122/97 LANSYYFDKNGDV-PLRPTTTVEAYWRSRRFDLGDYRISS----------
Rv1393c|M.tuberculosis_H37Rv LANSYYFDKNGDV-PLRPTTTVEAYWRSRRFDLGDYRISS----------
MMAR_2207|M.marinum_M RANSYYFDKNGDV-PLRPTTTVEAYWRGRHFDLDNYRFGR----------
MUL_1793|M.ulcerans_Agy99 RANSYYFDKNGDV-PLRPTTTVEAYWRGRHFDLDDYRFGR----------
MAV_3378|M.avium_104 LANSYYFDKNGDV-PLRPGTTPEVYWRSRRFDLDDYRFTG----------
Mvan_2671|M.vanbaalenii_PYR-1 LSNSYYFDQHGDV-PLRPASTPEAYWRSRRFPIDDYEFSC----------
Mflv_4607|M.gilvum_PYR-GCK GANSYYFDKHGDV-PLRPTTTVESIWRSRRFDLADYRFERRPAKKADTAP
MAB_0513|M.abscessus_ATCC_1997 TANTYYIDNHGDS-PFRPGGFGEMYFHNKYFRLDNYRYGTETIAPAVESA
MSMEG_0816|M.smegmatis_MC2_155 SARSYYFNPSGEATLLRPMTTRRAVAEASRFPLSDYTFA-----------
TH_2450|M.thermoresistible__bu GVNTYYVNSQRDTVYHRPQTITESLVFAHRPPLTDYRFERRPAAARSAVR
MLBr_00065|M.leprae_Br4923 SRTPWRLNQNYLR-DIRLIRRGKVADEGLLFAKKTTPVTV----------
.: .: * .
Mb1428c|M.bovis_AF2122/97 -----------
Rv1393c|M.tuberculosis_H37Rv -----------
MMAR_2207|M.marinum_M -----------
MUL_1793|M.ulcerans_Agy99 -----------
MAV_3378|M.avium_104 -----------
Mvan_2671|M.vanbaalenii_PYR-1 -----------
Mflv_4607|M.gilvum_PYR-GCK QKVDTAG----
MAB_0513|M.abscessus_ATCC_1997 PKRKRNKEVVR
MSMEG_0816|M.smegmatis_MC2_155 -----------
TH_2450|M.thermoresistible__bu ALRHAEGNEAV
MLBr_00065|M.leprae_Br4923 -----------