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MDRKFDPDHEIIIIGAGFSGIGCGISLLKAGFTDFLMVDDADGVGGTWHWNTYPGIAVDIPSYSYQFSYE MRPDWSRTYAHGNELKGYAEQCVEKYKLGDHIRFNTTITAACFDENATFWRLTTAKGEEITARFVVNCSG VLSRPKWPEIQGVRDFAGVTLHTARWDDSEDLSGKRVAVIGTGASAVQLIPEIAKKQGV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2074 | - | - | 100% (199) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_4024c | - | 8e-62 | 59.89% (187) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0513 | - | 1e-55 | 49.48% (192) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 2e-70 | 62.77% (188) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 8e-79 | 71.43% (189) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 3e-70 | 62.77% (188) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 3e-19 | 28.50% (193) | putative monooxygenase |
| M. marinum M | MMAR_3138 | - | 8e-91 | 80.21% (187) | monooxygenase |
| M. avium 104 | MAV_3378 | - | 4e-70 | 63.83% (188) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 1e-53 | 46.28% (188) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_3452 | - | 2e-48 | 47.54% (183) | PUTATIVE lipolytic enzyme |
| M. ulcerans Agy99 | MUL_1793 | - | 3e-68 | 62.84% (183) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 9e-66 | 63.16% (190) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2074|M.abscessus_ATCC_1997 MDRKFD---------------PDHEIIIIGAGFSGIGCGISLLKAG-FTD
MMAR_3138|M.marinum_M MGSESG---------------QHYEIVIVGAGFSGIGTAISLLKAG-FAD
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLLKEG-FSD
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLDRAG-FSD
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLDRAG-FSD
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLDKAG-FGD
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLDKAG-LPD
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLDRVG-MSD
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLKKMS-FDD
TH_3452|M.thermoresistible__bu -------------------MARNLSVGIIGAGPGGIALGIFLRRAG-FTD
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
::*** .*:. . * .
MAB_2074|M.abscessus_ATCC_1997 FLMVDDADGVGGTWHWNTYPGIAVDIPSYSYQFSYEMRPDWSRTYAHGNE
MMAR_3138|M.marinum_M FLIVDDADGVGGTWHWNTYPGIAVDIPSYSYQFSYEMRTSWSRTYAHGDE
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MAV_3378|M.avium_104 YRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRE
Mvan_2671|M.vanbaalenii_PYR-1 YVVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHE
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
TH_3452|M.thermoresistible__bu FTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFELNSEWTRLWPAQPE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
: :.: **** ***: * : :. : .
MAB_2074|M.abscessus_ATCC_1997 LKGYAEQCVEKYKLGDHIRFNTTITAACFDENATFWRLTTAKGE---EIT
MMAR_3138|M.marinum_M LKAYAERCVEKYGLQNYIRFNTTVDEACFDEGAALWRLSCSSGQ---NLT
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELT
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLI
MAV_3378|M.avium_104 LKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVT
Mvan_2671|M.vanbaalenii_PYR-1 LKTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLS
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQ
TH_3452|M.thermoresistible__bu ILRYFERCAQRHRLGPHLRLNTEITSARWNPTSRQWMLTTGAGE---QHN
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
: * . . : : :*: : * . * :
MAB_2074|M.abscessus_ATCC_1997 ARFVVNCSGVLSRPK--WPEIQGVRDFAGVTLHTARWDDSEDLSGKRVAV
MMAR_3138|M.marinum_M ARFVINCSGVLSRPK--WPDIPGVRDFAGVTLHTARWDHTKDLTGKRVAV
Mflv_4607|M.gilvum_PYR-GCK ARFVINASGVLTRPK--SPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
Mb1428c|M.bovis_AF2122/97 ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MAV_3378|M.avium_104 ARFLISACGVLTVPN--LPDIDGVDSFAGITMHTARWDHGQDLRGKRVAV
Mvan_2671|M.vanbaalenii_PYR-1 ARFLVNAGGVLTVPK--LPDIAGVDSFAGVTMHTARWDHTQDLRGKRVAI
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAV
TH_3452|M.thermoresistible__bu FDVVVSAVGMFTRPV--MPDLVEEEPFTGTLMHSARWDHGIDLHGKRIAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
.:. . * . * : * * :*. * . .:. :
MAB_2074|M.abscessus_ATCC_1997 IGTGASAVQLIPEIAKK-QGV-----------------------------
MMAR_3138|M.marinum_M IGTGASAVQLIPEVAKI-ASSLTVFQRTPIYCLPKPDFSIPSWAATVMRL
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAKD-VDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVRWAMR-
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVRWAMR-
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAPI-VKHLTVFQRTPIWCFPKFDFPLPAALRWAMR-
MAV_3378|M.avium_104 IGTGASAVQVIPEIAPI-VSSLTVFQRTPIWCFPKLDVPLPAPARWAMR-
Mvan_2671|M.vanbaalenii_PYR-1 IGTGASAVQVIPEIAPI-VERLTVFQRTPIWCFPKFDVPLSKTAQTMMR-
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAER-VAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
TH_3452|M.thermoresistible__bu LGTGSTASQLIPELAKI-ADRVYSVQRSPTWILPKPDRPYSDRERWVFRH
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQP--AKDKIAARLNRW
:*:*::* ::* :*
MAB_2074|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M VPGAQLMTRTASQAFVEFTFPIAAHFHSLIP-VSDLMEEAAKRYMRRAVD
Mflv_4607|M.gilvum_PYR-GCK APGAQIAARGASQAFVELTFPVAAHFHTAIP-LASAIERAAISYMRRQVT
Mb1428c|M.bovis_AF2122/97 IPGGKAVHRLLSQAFVEATFPIAAHYFAVFP-LAKHMESAGRRYLRQQVH
Rv1393c|M.tuberculosis_H37Rv IPGGKAVHRLLSQAFVEATFPIAAHYFAVFP-LAKHMESAGRRYLRQQVH
MUL_1793|M.ulcerans_Agy99 IPGGKALQRLLSQAYVEATFPISAHYFTVFP-LARWSAVLGRRYLRQRVD
MAV_3378|M.avium_104 FPGGKALQRLLSQAYVELTFPISAHYFTVIP-LAKRMAALGRAYLRRQVR
Mvan_2671|M.vanbaalenii_PYR-1 LPFGKSLQRLISQAFVELTFPLAAQYFTVNP-MAKRMGAVGRAYLRKQVD
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVRAITDAIYAFMVDTAVLKHRYFRRLNIAAADLGRLHLAASIR
TH_3452|M.thermoresistible__bu VPFAKRIYR--TRLWLRSEANISVIEDGSEK--TEEFKAIALKMLEATVP
MLBr_00065|M.leprae_Br4923 LPDKYAYTAVRWKNILRQSALYGACQKWPQRMRNILLGHVARRLPKGYDV
MAB_2074|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M DPVTRDQLIPRYSLGCKRPSFHNSYLATYNRRNVSLETSGITHVDHASVH
Mflv_4607|M.gilvum_PYR-GCK DPVVREKLTPRYALGCKRPSFHNEYLKTFNRENVLLETNPITRVDETAVI
Mb1428c|M.bovis_AF2122/97 DPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVA
Rv1393c|M.tuberculosis_H37Rv DPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVA
MUL_1793|M.ulcerans_Agy99 DPVVRDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEPIEKITPTSVA
MAV_3378|M.avium_104 DPAVREQLTPRYAVGCKRPGFHNGYLATFNRDNVRLVTEPIDKITPDAVA
Mvan_2671|M.vanbaalenii_PYR-1 DPVLRDKLTPRYAVGCKRPGFHNTYLSTFNRDNVDLVTEPIDKITGSGVS
MSMEG_0816|M.smegmatis_MC2_155 DPDLRSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADGIDHVEPDGIV
TH_3452|M.thermoresistible__bu DEEMRRRLTPDHPLGCKRLVFSSDYLAALMRPNVEVVSSPARALRGDTLI
MLBr_00065|M.leprae_Br4923 QKHFGPHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDAIDRFTSTGIR
MAB_2074|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M TEDGKSYPIDVMVLATGFKVMES----GNMPTYVLKGRGGVEQSAWWDEH
Mflv_4607|M.gilvum_PYR-GCK TADGVRHEIDVLVLATGFKVMES----DSMPTYSLRGVAGRDQAQWWDEN
Mb1428c|M.bovis_AF2122/97 TTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGGASLSRFWDEH
Rv1393c|M.tuberculosis_H37Rv TTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGGASLSRFWDEH
MUL_1793|M.ulcerans_Agy99 TDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAGRSLSQFWEEH
MAV_3378|M.avium_104 TTDGETHEIDVLILATGFKVMDP----DSVPTFAVTGSGGRSLSRFWDEH
Mvan_2671|M.vanbaalenii_PYR-1 TTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTGPGGRSLARFWDDN
MSMEG_0816|M.smegmatis_MC2_155 NADGSKTVIDTLVLATGFDLWEA-----NFPAIEVIGRQGRDLGKWWRET
TH_3452|M.thermoresistible__bu TEDGTERRVDVVVCATGYAAADY------LGQIEVVGERQRSLREVWRDG
MLBr_00065|M.leprae_Br4923 LKSGNELRADIIVTATGLNLQLFG------------GAVATVDGQPVDLA
MAB_2074|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M RLQAFEGVSVPGFPNHFNIFGPYGYNGS-SYFTLIEAQSRHIVRCLRRAR
Mflv_4607|M.gilvum_PYR-GCK RLQAYEGVSVPGFPNHFSVFGPYGYNGS-SYFALIEAQAGHILRCLRHAR
Mb1428c|M.bovis_AF2122/97 RLQAYEGVSVPGYPNFFTVFGPYGYVGS-SYFALIETQAHHIIRCLKRAR
Rv1393c|M.tuberculosis_H37Rv RLQAYEGVSVPGYPNFFTVFGPYGYVGS-SYFALIETQAHHIIRCLKRAR
MUL_1793|M.ulcerans_Agy99 RAQAYQGVSVPGYRNFFAVFGPYGYVGS-SYFALIETQTHHILRCLKRAR
MAV_3378|M.avium_104 RLQAYEGVTVPGFPNLFTVFGPYGYVGS-SYFALIEAQTHHIVRCLKRAQ
Mvan_2671|M.vanbaalenii_PYR-1 RLQAYEGVSVPGFPNFFTVFGPYGYVGS-SYFALIEAQTRHIVRCLDAAR
MSMEG_0816|M.smegmatis_MC2_155 RFQAYQGVSMPYFPNYLSLAGPYAFLGL-NFFNTMEYQMRLMERLLGEVA
TH_3452|M.thermoresistible__bu -AYAYLGMTVPGFPNFFMLYGPNTNVGSNSVLFILEAQARYVVKALKRLR
MLBr_00065|M.leprae_Br4923 QTMSYKGMMLSGLPNMIYTVG-YTNASWTLKADLVSEFFCRLLNYMNAND
MAB_2074|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3138|M.marinum_M TLKADYVEVRQQANDRYFGDMVSRRHRQVFWQPSCSNANSYYFDKHGDVP
Mflv_4607|M.gilvum_PYR-GCK TADSNYVEVREEANQRFFAEMLARRHTQVFWQDSCAGANSYYFDKHGDVP
Mb1428c|M.bovis_AF2122/97 RTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGDVP
Rv1393c|M.tuberculosis_H37Rv RTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGDVP
MUL_1793|M.ulcerans_Agy99 RDGATRVEVTEEANARYFAEMMRRRYRQVFWQDSCRRANSYYFDKNGDVP
MAV_3378|M.avium_104 RLGATRVEVSEEANDRYFAEMMRRRHRQIFWQDSCRLANSYYFDKNGDVP
Mvan_2671|M.vanbaalenii_PYR-1 RRRATRVEVRREANDRYFAEMMRKRHRQIFWQDSCQLSNSYYFDQHGDVP
MSMEG_0816|M.smegmatis_MC2_155 RRDARTFEVTEEANRRYLDRMTDALGDSLFTLGNCASARSYYFNPSGEAT
TH_3452|M.thermoresistible__bu RRDTSYIAVRPDTAAAFLAKVDQWMQGKVWS----TQCNNYFRAPNGRVV
MLBr_00065|M.leprae_Br4923 FDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQGSRTPWRLNQNYLR
MAB_2074|M.abscessus_ATCC_1997 -------------------------------------------
MMAR_3138|M.marinum_M -LRPSTTLETYWRSRTFRLSDYRFERRAESVGAR---------
Mflv_4607|M.gilvum_PYR-GCK -LRPTTTVESIWRSRRFDLADYRFERRPAKKADTAPQKVDTAG
Mb1428c|M.bovis_AF2122/97 -LRPTTTVEAYWRSRRFDLGDYRISS-----------------
Rv1393c|M.tuberculosis_H37Rv -LRPTTTVEAYWRSRRFDLGDYRISS-----------------
MUL_1793|M.ulcerans_Agy99 -LRPTTTVEAYWRGRHFDLDDYRFGR-----------------
MAV_3378|M.avium_104 -LRPGTTPEVYWRSRRFDLDDYRFTG-----------------
Mvan_2671|M.vanbaalenii_PYR-1 -LRPASTPEAYWRSRRFPIDDYEFSC-----------------
MSMEG_0816|M.smegmatis_MC2_155 LLRPMTTRRAVAEASRFPLSDYTFA------------------
TH_3452|M.thermoresistible__bu TQWPRSARAFWAMTRRFRSADYLFEPAPDMSEVSADARPVASR
MLBr_00065|M.leprae_Br4923 DIRLIRRGKVADEGLLFAKKTTPVTV-----------------