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IKPELPQGTTCAIAGGGPAGMMLALLLARAGIDVTVLEKHPDFLRDFRGDTVHASTLNLIDELGLGPRFA AMPHNLVEQVTVDLGEQTFRLGDLNRLPGPHKHIAMAPQWDFLEMLATAAETEPTFRLRRSTEVTGLLRS GDRITGIEYRTASGETGALKADLTVACDGRGSALRAAAGMRPRQFGVPIDIWWFRLPKHPDDPQGPRARV GANRFMVLLDRGDYFQCGYLIGKGTDSQMRSGDVQVLRDRVAEMAPWLAARTNAIASWDDVKLLDIQLNR LRKWYRDGLLFIGDAAHAMSPVGGVGINLAIADAVATARILAEPLRTGTLTTADLRKVQLRRWVPTALIQ RIQRAVHRRVFSAVDSSTTAASNAKIASVLSIATKYPWLQAVPAYGVAIGPLPEHAPDFARRSPID*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1646c | - | - | 100% (417) | hypothetical protein MAB_1646c |
| M. abscessus ATCC 19977 | MAB_4756c | - | e-103 | 48.55% (414) | hypothetical protein MAB_4756c |
| M. abscessus ATCC 19977 | MAB_2614 | - | 2e-86 | 43.46% (405) | hypothetical protein MAB_2614 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1780 | - | 1e-114 | 51.72% (406) | hypothetical protein Mb1780 |
| M. gilvum PYR-GCK | Mflv_0304 | - | 1e-118 | 53.19% (408) | hypothetical protein Mflv_0304 |
| M. tuberculosis H37Rv | Rv1751 | - | 1e-114 | 51.72% (406) | hypothetical protein Rv1751 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3720 | - | 1e-128 | 57.43% (397) | FAD-dependent oxidoreductase |
| M. avium 104 | MAV_4364 | - | 6e-83 | 44.47% (398) | hypothetical protein MAV_4364 |
| M. smegmatis MC2 155 | MSMEG_4962 | - | 1e-125 | 54.88% (410) | hypothetical protein MSMEG_4962 |
| M. thermoresistible (build 8) | TH_2800 | - | 2e-11 | 24.04% (337) | PUTATIVE putative monooxygenase, FAD-binding |
| M. ulcerans Agy99 | MUL_3663 | - | 1e-132 | 56.25% (416) | hypothetical protein MUL_3663 |
| M. vanbaalenii PYR-1 | Mvan_0442 | - | 1e-120 | 54.03% (409) | hypothetical protein Mvan_0442 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3720|M.marinum_M --------------------------------------------------
MUL_3663|M.ulcerans_Agy99 ---------------------------------------------MPQPS
MAB_1646c|M.abscessus_ATCC_199 -------------------------------------------MIKPELP
Mb1780|M.bovis_AF2122/97 MIATMPSMARRSRHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMG
Rv1751|M.tuberculosis_H37Rv MIATMPSMARRSRHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMG
Mflv_0304|M.gilvum_PYR-GCK -MR----------DDDTVS-------------------------------
Mvan_0442|M.vanbaalenii_PYR-1 -MRKQLGRPSGSCHHDQMN-------------------------------
MSMEG_4962|M.smegmatis_MC2_155 -MT-----------------------------------------------
MAV_4364|M.avium_104 --------------------------------------------------
TH_2800|M.thermoresistible__bu ----------------------------------------------VSGP
MMAR_3720|M.marinum_M ---------------MLGLLLARAGVDVTVMEKHADFLRDFRGDTVHAST
MUL_3663|M.ulcerans_Agy99 ETTSVLVAGGGPAGMVLGLLLARAGVDVTVMEKHADFLRDSRGDTVHAST
MAB_1646c|M.abscessus_ATCC_199 QGTTCAIAGGGPAGMMLALLLARAGIDVTVLEKHPDFLRDFRGDTVHAST
Mb1780|M.bovis_AF2122/97 ETTTCAIIGGGPAGMVLGLLLARAGVQVTLLEKHGDFLRDFRGDTVHPTT
Rv1751|M.tuberculosis_H37Rv ETTTCAIIGGGPAGMVLGLLLARAGVQVTLLEKHGDFLRDFRGDTVHPTT
Mflv_0304|M.gilvum_PYR-GCK DTTTCAIVGGGPAGMVLGLLLARAGVEVTVLEKHADFLRDFRGDTVHPTT
Mvan_0442|M.vanbaalenii_PYR-1 AKTTCAVVGGGPAGMVLGLLLARAGVEVTVLEKHADFLRDFRGDTVHPTT
MSMEG_4962|M.smegmatis_MC2_155 EKTTCAVVGGGPAGMVLGLLLARAGIEVTVFEKHADFLRDFRGDTVHPAT
MAV_4364|M.avium_104 --------------MVHALLLARAGIPVVVLEKHNDFLRDFRGDTVHPTT
TH_2800|M.thermoresistible__bu EQAPVLIVGAGPAGLATAYVLGRNGIPSVVCDQHSGIHPHPRAHVINTRS
. :*.* *: .: ::* .: . *...::. :
MMAR_3720|M.marinum_M LRLLDELGLGSQFAQIPHRLIDTISMKV-QGQPVDL-DLKHLPGA-----
MUL_3663|M.ulcerans_Agy99 LRLLDELGLGSQFAQIPHRLIDTISMKV-QGQPVDL-DLKHLPGA-----
MAB_1646c|M.abscessus_ATCC_199 LNLIDELGLGPRFAAMPHNLVEQVTVDL-GEQTFRLGDLNRLPGP-----
Mb1780|M.bovis_AF2122/97 MRLLDELGLWERFAALPYSEVRTATLHS-NGRAVTYIDFERLHQP-----
Rv1751|M.tuberculosis_H37Rv MRLLDELGLWERFAALPYSEVRTATLHS-NGRAVTYIDFERLHQP-----
Mflv_0304|M.gilvum_PYR-GCK LRLLDDLGLWPRFADISHSRLDHATVDVGAGRSVTMVDFRRLRQP-----
Mvan_0442|M.vanbaalenii_PYR-1 LRLIDELGLWPKFSALPHSRLERATVDVGAGRTITVVDFGRLRQP-----
MSMEG_4962|M.smegmatis_MC2_155 LRLLDELGLFEKFDALPHSRVERARFDL-GGREVTVVDFGRLNLP-----
MAV_4364|M.avium_104 LRIMDELGLIDEFLRLPHTKIDTVAFDT-DGSIRTFGNFKVLKRLGF---
TH_2800|M.thermoresistible__bu MELFRSWGIADAIARDEQAFDAGAGVRIVWKHSVSGEELGCIDLLDAPVE
:.:: . *: : . :: :
MMAR_3720|M.marinum_M ---------HQHIALVPQWDFLELLAAAAEAEPTFRLLRSTEVTGVLWGD
MUL_3663|M.ulcerans_Agy99 ---------HQHIALVPQWDFLELLAAAAEAEPTFRLLRSTEVTGVLWGD
MAB_1646c|M.abscessus_ATCC_199 ---------HKHIAMAPQWDFLEMLATAAETEPTFRLRRSTEVTGLLRSG
Mb1780|M.bovis_AF2122/97 ---------YPYVAMVPQWDLLNLLAEAAQAEPSFTLRMKTEVTGLLREG
Rv1751|M.tuberculosis_H37Rv ---------YPYVAMVPQWDLLNLLAEAAQAEPSFTLRMKTEVTGLLREG
Mflv_0304|M.gilvum_PYR-GCK ---------HPYIAMVPQWDLLNLLADAGRAEPTFTLRMSTEVTGVLREG
Mvan_0442|M.vanbaalenii_PYR-1 ---------HPYIAMVPQWDLLNLLAEAGEAEPTFTLRMCTEATGLIREG
MSMEG_4962|M.smegmatis_MC2_155 ---------HRYIALVPQWDFLDLLADAAKEEPTFTLRMQTEVTGLLKDG
MAV_4364|M.avium_104 --------NQPYIAMMPQWDFLDFIAEKASAYPEFTLIRNAEVTDLILED
TH_2800|M.thermoresistible__bu SIERRRAASPVGLISCPQDRIQRLMVDAVLRQGMSRIDYDTRVVEITDAA
: ** : ::. : :... :
MMAR_3720|M.marinum_M GPDRGRVVGVTYRAQSGETKHMHADLTVACDGRGSTVRSALGMATR---S
MUL_3663|M.ulcerans_Agy99 GPDPGRVVSATYRAQSGETKHMHADLTVACDGRGSTVRSALGMATR---S
MAB_1646c|M.abscessus_ATCC_199 D----RITGIEYRTASGETGALKADLTVACDGRGSALRAAAGMRPR---Q
Mb1780|M.bovis_AF2122/97 G----KVTGVRYQGAEG-PGELRAELTVACDGRWSIARHEAGLKAR---E
Rv1751|M.tuberculosis_H37Rv G----KVTGVRYQGAEG-PGELRAELTVACDGRWSIARHEAGLKAR---E
Mflv_0304|M.gilvum_PYR-GCK S----RVTGVRYETADG-TGELQAGLTVACDGRGSLLREKTGLRTQ---E
Mvan_0442|M.vanbaalenii_PYR-1 G----RVVGVRYQDPDG-PGELRADLTVGCDGRGSVLRGLAGLQVR---E
MSMEG_4962|M.smegmatis_MC2_155 D----TVTGVRYHGPDG-PGELRADLTVACDGRTSRVRKEAGLAPR---E
MAV_4364|M.avium_104 D----RVAGVRTP-----HDEVRADLVIAADGRKSAVRAAAGLRTA---Q
TH_2800|M.thermoresistible__bu TG-----VEVTAESRGK-PRRFRADYVVNAEGAGGRLRSALGIEMDGIPF
. .:* .: .:* . * *:
MMAR_3720|M.marinum_M FGAPMDVWWFRLPR-RPDDPTGLAGIFNSGHGGIAIDRGDYYQIAYIIPK
MUL_3663|M.ulcerans_Agy99 FGAPMDVWWFRLPR-RPDDPTGLAGIFNSGHGGIAIDRGDYYQIAYIIPK
MAB_1646c|M.abscessus_ATCC_199 FGVPIDIWWFRLPK-HPDDPQGPRARVGANRFMVLLDRGDYFQCGYLIGK
Mb1780|M.bovis_AF2122/97 FPVNFDVWWFKLPR-EGDAEFSFLPRFSPGKGLGVIPREGYFQIAYLGPK
Rv1751|M.tuberculosis_H37Rv FPVNFDVWWFKLPR-EGDAEFSFLPRFSPGKGLGVIPREGYFQIAYLGPK
Mflv_0304|M.gilvum_PYR-GCK FPVGFDVWWFRLPRPETDEMYTLFPRLAPGRAMIVIPREGYLQIALLIEK
Mvan_0442|M.vanbaalenii_PYR-1 FPVSFDAWWFRLPRPADDSIYTLVPRIAPGKAMIVIPREGYLQIAMLIPK
MSMEG_4962|M.smegmatis_MC2_155 YPVPFDVGWFRIDR-IKETAYQLTPRISSGQALILIPREGYFQAGCFLPK
MAV_4364|M.avium_104 AHSPMDVLWFRLKW-RPGDPRELFGVFRKGLMMAMIYRGDYWQVAYLMPK
TH_2800|M.thermoresistible__bu IADQVTSYFHADLSEWTGERPPLLQWIINTDVQGTFIAMGQNRWTFTIGF
. :. . : . :
MMAR_3720|M.marinum_M GSDAQLRAQGIEALHRALADLMPWLADRVDALKSLDDVKLLDVQLNRLRR
MUL_3663|M.ulcerans_Agy99 GSDAQLRAQGIEALHRALADLMPWLADRVDALKSFDDVKLLDVQLNRLRR
MAB_1646c|M.abscessus_ATCC_199 GTDSQMRSGDVQVLRDRVAEMAPWLAARTNAIASWDDVKLLDIQLNRLRK
Mb1780|M.bovis_AF2122/97 GTDAQLRERGIEEFRRDVSELLPEATASVAALASTDEVKHLNVKVNRLRR
Rv1751|M.tuberculosis_H37Rv GTDAQLRERGIEEFRRDVSELLPEATASVAALASMDEVKHLNVKVNRLRR
Mflv_0304|M.gilvum_PYR-GCK GTDAALRAHGLDAFHADVLALLPEAAGTVGSIASLDEVKMLDVKLNRLRC
Mvan_0442|M.vanbaalenii_PYR-1 GTDAERRARGLDAFRADVLALLPEAATTIETITSLDDVKHLDVRLNRLRR
MSMEG_4962|M.smegmatis_MC2_155 GGEKQLHARGLEVFRAQVAEAVPEAS--VDRLTSWDDVKVLDVKLNRLRR
MAV_4364|M.avium_104 G--ASPKGGSLEEFKERIVTAQPRLREHVNDLTSWDDTSELDVRVDRLET
TH_2800|M.thermoresistible__bu GATDEAR-RALDPQRCVELIRLAIGPAGSDVDIDFRSAGSWTLCATTART
* : :: : . . .. : .
MMAR_3720|M.marinum_M WYCDGALCIGDAAHAMSPVGGVGINLALADAVATARMLAPSLR-------
MUL_3663|M.ulcerans_Agy99 WYCDGALCIGDAAHAMSPVGGVGINLALADAVATARMLAPSLR-------
MAB_1646c|M.abscessus_ATCC_199 WYRDGLLFIGDAAHAMSPVGGVGINLAIADAVATARILAEPLR-------
Mb1780|M.bovis_AF2122/97 WHIDGLLCIGDAAHAMSPVAGVGINLAVQDAVAAATILAEPLR-------
Rv1751|M.tuberculosis_H37Rv WHIDGLLCIGDAAHAMSPVAGVGINLAVQDAVAAATILAEPLR-------
Mflv_0304|M.gilvum_PYR-GCK WHIEGMLCIGDAAHAMSPAGGVGINLAIQDAVAAARLLAEPLR-------
Mvan_0442|M.vanbaalenii_PYR-1 WHTDGLLFIGDAAHAMSPAGGVGINVAIQDAVATARLLADPLR-------
MSMEG_4962|M.smegmatis_MC2_155 WYRDGLLCIGDAAHAMSPVGGVGINLAIADAVAAARILAEPLR-------
MAV_4364|M.avium_104 WWRTGLLCIGDAAHAMSPAGGVGINLAVADAVAAANILCAPLQ-------
TH_2800|M.thermoresistible__bu YRAGRVFLVGDAAHQFPPTGGFGMNTGLADADNLGWKLAAVLHGWADEEL
: : :***** :.*..*.*:* .: ** . *. *:
MMAR_3720|M.marinum_M ---------VGRVSTGQLARVQARRWAPTAFLQG--------------IQ
MUL_3663|M.ulcerans_Agy99 ---------VGRVSTGQLARVQARRWAPTAFLQG--------------IQ
MAB_1646c|M.abscessus_ATCC_199 ---------TGTLTTADLRKVQLRRWVPTALIQR--------------IQ
Mb1780|M.bovis_AF2122/97 ---------EHRVSSRHLAAVRRRRAFPTAVTQA--------------VQ
Rv1751|M.tuberculosis_H37Rv ---------EHRVSSRHLAAVRRRRAFPTAVTQA--------------VQ
Mflv_0304|M.gilvum_PYR-GCK ---------RGTVTGRDLARVRRRRILPTVVTQA--------------LQ
Mvan_0442|M.vanbaalenii_PYR-1 ---------RGAVTERDLAAVRRRRVVPAALTQA--------------LQ
MSMEG_4962|M.smegmatis_MC2_155 ---------TGRVTRRDLAAVEKRRYVPAAVIQA--------------VQ
MAV_4364|M.avium_104 ---------QGRVTDRDLAKVQRRRELPTRIVQA--------------VQ
TH_2800|M.thermoresistible__bu LDTYESERRPVALANSEFSVTNALKMASTGIGPTGPQFAAELESDDPSVA
:: .: .. : .: . :
MMAR_3720|M.marinum_M RAIH----AAIVA-----------------VAVTGGPPQPPPVVR-----
MUL_3663|M.ulcerans_Agy99 RAIH----AAIVA-----------------VAVTGGPPQPPPVVR-----
MAB_1646c|M.abscessus_ATCC_199 RAVHRRVFSAVDS-----------------STTAASNAKIASVLS-----
Mb1780|M.bovis_AF2122/97 RVLHRRLLGPLLQ-----------------GRDPTPPAALLGLV------
Rv1751|M.tuberculosis_H37Rv RVLHRRLLGPLLQ-----------------GRDPTPPAALLGLV------
Mflv_0304|M.gilvum_PYR-GCK RLIDRRLLGPIVR-----------------GGSGGPSPGLIRTV------
Mvan_0442|M.vanbaalenii_PYR-1 RQIDKRFLRPILD-----------------GDVTGPPPALVRAI------
MSMEG_4962|M.smegmatis_MC2_155 RVLHIGLRRALLG-----------------GEIRQPPERVLKAVGA----
MAV_4364|M.avium_104 VLMQDNAIAPNLN-----------------GDLS--PIHVPKIVG-----
TH_2800|M.thermoresistible__bu AAVRDRIRNAIPEQRPHFDHLELEIGYVYPGDASDGDPVSTPVVGGRLPH
: . :
MMAR_3720|M.marinum_M ------------------LVSRSVPARRIMGYLVAIGPLPEHAPKYARRA
MUL_3663|M.ulcerans_Agy99 ------------------LVSRSVPVRRIMGYLVAIGPLPEHAPKYPRRA
MAB_1646c|M.abscessus_ATCC_199 ------------------IATKYPWLQAVPAYGVAIGPLPEHAPDFARRS
Mb1780|M.bovis_AF2122/97 --------------------ERLPWLSAVPAYFVGVGVRPEHAPAFARRG
Rv1751|M.tuberculosis_H37Rv --------------------ERLPWLSAVPAYFVGVGVRPEHAPAFARRG
Mflv_0304|M.gilvum_PYR-GCK --------------------ERLPWLTVIPAYLVGVGVRPERAPRFARRR
Mvan_0442|M.vanbaalenii_PYR-1 --------------------ERAPWLTFVPAYLVGVGVRPERAPEFAKRR
MSMEG_4962|M.smegmatis_MC2_155 ------------------VLSRFPGLAKVPAYLVGVGPLPEHAPDFARRS
MAV_4364|M.avium_104 ----------------------FGPLQAIPPLVVGRGFRPEHVRTPDVHA
TH_2800|M.thermoresistible__bu RWITRITPGQGTASTLDLLGDGFTLLTGPAGAAWTAGVRDVAVPVRTLTA
* .
MMAR_3720|M.marinum_M R-------------------------------------------------
MUL_3663|M.ulcerans_Agy99 R-------------------------------------------------
MAB_1646c|M.abscessus_ATCC_199 PID-----------------------------------------------
Mb1780|M.bovis_AF2122/97 PGNRKGP-------------------------------------------
Rv1751|M.tuberculosis_H37Rv PGNRKGP-------------------------------------------
Mflv_0304|M.gilvum_PYR-GCK PQ------------------------------------------------
Mvan_0442|M.vanbaalenii_PYR-1 PT------------------------------------------------
MSMEG_4962|M.smegmatis_MC2_155 R-------------------------------------------------
MAV_4364|M.avium_104 R-------------------------------------------------
TH_2800|M.thermoresistible__bu GVDFAFTGPSDTTFLADDGAVLVRPDGHIAWIATHLPADPAAELTSALRG
MMAR_3720|M.marinum_M ------------------
MUL_3663|M.ulcerans_Agy99 ------------------
MAB_1646c|M.abscessus_ATCC_199 ------------------
Mb1780|M.bovis_AF2122/97 ------------------
Rv1751|M.tuberculosis_H37Rv ------------------
Mflv_0304|M.gilvum_PYR-GCK ------------------
Mvan_0442|M.vanbaalenii_PYR-1 ------------------
MSMEG_4962|M.smegmatis_MC2_155 ------------------
MAV_4364|M.avium_104 ------------------
TH_2800|M.thermoresistible__bu VHLSADAARSASGQGASR