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AEQSRWQKIKSRPVETYNKTWLGFIAIAVIGALVGGMLLVKAIGFGYTTYTAEFAQAASLRAGQPITVAG IPMGTVTSMKLVGDHVEAKLSVSDDVKLGKDTKAAIRVTTILGSRYLDLQPEGPGSLPNKTIDLAHTEVP YDLQATLRDATNTFDQVDFDKVAQSLSILGKQLDGLPEVVPQAMQNIQTLSQIIAERRDQLGTLLKSSEK VTNTLRHQQQGIGTLINQGQNLIGEFVVRRGTFHAMMQSLTNLVQQLSKITIKDRPQLDEMLRTLHQLTD MLGQHDDLLRNILQITPVTLRGVANATGTGNAIEFNAPNGLAVDSWMCAISGRAKQFGMIQYFKDCK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1008c | - | - | 100% (348) | putative MCE family protein |
| M. abscessus ATCC 19977 | MAB_4514c | - | e-156 | 75.86% (348) | putative Mce family protein |
| M. abscessus ATCC 19977 | MAB_4566c | - | e-123 | 60.52% (347) | putative Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0177 | mce1C | 9e-28 | 26.87% (294) | MCE-family protein MCE1C |
| M. gilvum PYR-GCK | Mflv_0008 | - | 1e-129 | 63.22% (348) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv0171 | mce1C | 5e-28 | 26.87% (294) | MCE-family protein MCE1C |
| M. leprae Br4923 | MLBr_02591 | mce1C | 3e-28 | 26.49% (302) | putative secreted protein |
| M. marinum M | MMAR_3866 | mce5C | 1e-125 | 63.64% (352) | Mce family protein, Mce5C |
| M. avium 104 | MAV_2386 | - | 1e-132 | 65.51% (345) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_1145 | - | 1e-123 | 61.54% (338) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2869 | - | 1e-123 | 63.47% (334) | PUTATIVE virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_3798 | mce5C | 1e-123 | 63.35% (352) | Mce family protein, Mce5C |
| M. vanbaalenii PYR-1 | Mvan_0961 | - | 1e-129 | 62.64% (348) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3866|M.marinum_M MADSSLRQRLSALQRRPLESYNKTWLGFAAVAVVAVVIAAMLVVHLAGAG
MUL_3798|M.ulcerans_Agy99 MADSSLRHRLSALQRRPLESYNKTWLRFAAVAVVAVVIAAMLVVHLAGAG
MAV_2386|M.avium_104 -----MRQRLSALTKRPLESYNKTWLGFVAVAVVAAVIAVMLVVHALGAG
MAB_1008c|M.abscessus_ATCC_199 MAE---QSRWQKIKSRPVETYNKTWLGFIAIAVIGALVGGMLLVKAIGFG
Mflv_0008|M.gilvum_PYR-GCK -----MAEQTK-RRRRRLESYHKAWLGTVAVVVVAVLVGALLLIKAADVG
Mvan_0961|M.vanbaalenii_PYR-1 -----MAERRK-WPRRPLESYHSAWLGFAAVAVVAVLIGAMLLIKGADVG
MSMEG_1145|M.smegmatis_MC2_155 -----MAEARKARRRKPLESYNRLWLGVVAVAVVSVLIGAMLLVRVADIG
TH_2869|M.thermoresistible__bu -----------------LETYSRTTLGVIAVAVVAVLVGALLVVKAAGIG
Mb0177|M.bovis_AF2122/97 --------------MRTLEPPNRMRIGLMGIVVALLVVAVGQSFTSVPML
Rv0171|M.tuberculosis_H37Rv --------------MRTLEPPNRMRIGLMGIVVALLVVAVGQSFTSVPML
MLBr_02591|M.leprae_Br4923 --------------MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPIL
:* .: * ::. .
MMAR_3866|M.marinum_M YRR--YTAEFLQAAALRAGNPIAIAGIPVGTVTSMKLVGDHVEAGLRIRD
MUL_3798|M.ulcerans_Agy99 YRR--YTAEFLQAAALRAGNPIAIAGIPVGTVTSMKLVGDHVEAGLRIRD
MAV_2386|M.avium_104 YRH--YTAEFAQAASLRAGNPIVVAGIPVGTVTSMKLVGDHVEAGLKVRD
MAB_1008c|M.abscessus_ATCC_199 YTT--YTAEFAQAASLRAGQPITVAGIPMGTVTSMKLVGDHVEAKLSVSD
Mflv_0008|M.gilvum_PYR-GCK YRT--FTAQFLQAAALQPGNPVSVAGIPVGEVTDMKLAGDHVEARFTVRN
Mvan_0961|M.vanbaalenii_PYR-1 YRK--YTAQFLQAAALQPGNPVTVAGIPVGEVTGMELAGDHVVADFTVRN
MSMEG_1145|M.smegmatis_MC2_155 YTQ--YTARFLQAAALKAGNPVTVAGIPVGEVKSMRLAGDHVEAKIKVRN
TH_2869|M.thermoresistible__bu YKE--YTARFLQAAALQPGNPITVAGIPVGEVLSMKLNGDHVEARLKVRG
Mb0177|M.bovis_AF2122/97 FAKPSYYGQFTDSGGLHKGDRVRIAGLGVGTVEGLKIDGDHIVVKFSIG-
Rv0171|M.tuberculosis_H37Rv FAKPSYYGQFTDSGGLHKGDRVRIAGLGVGTVEGLKIDGDHIVVKFSIG-
MLBr_02591|M.leprae_Br4923 FARPSYYGQFTDTGGLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIG-
: : ..* ::..*. *: : :**: :* * :.: ***: : :
MMAR_3866|M.marinum_M DVVLGKDSTATIRVTTILGSRYLAIEPDGAASLP-DHTFDLAHTAVPYDL
MUL_3798|M.ulcerans_Agy99 DVVLGKDSTATIRVTTILGSRYLAIEPDGAASLP-DHTFDLAHTAVPYDL
MAV_2386|M.avium_104 NISFGKDSRAQIRVTTILGSRYLALEPNGPARLP-GNTFDLAHTEVPYDL
MAB_1008c|M.abscessus_ATCC_199 DVKLGKDTKAAIRVTTILGSRYLDLQPEGPGSLP-NKTIDLAHTEVPYDL
Mflv_0008|M.gilvum_PYR-GCK DVDLGEDSRAVIKVTTILGSRYLSLEPEGTGALP-DRHFDLSHTEVPYDL
Mvan_0961|M.vanbaalenii_PYR-1 DVALGEDSRAVIKVTTILGSRYLSLEPEGPGSLP-DRRFDLAHTEVPYDL
MSMEG_1145|M.smegmatis_MC2_155 DVGLGKDSRAKIMVTTILGSRYLSLEPAGDGTLP-DRTFDLSHTDVPYDL
TH_2869|M.thermoresistible__bu DIRLGEHSRAVIKITTILGSRYLALYPDGPGTLP-DNTFDLKHTEVPYDL
Mb0177|M.bovis_AF2122/97 TNTIGTESRLAIRTDTILGRKVLEIEPRGAQALPPGGVLPVGQSTTPYQI
Rv0171|M.tuberculosis_H37Rv TNTIGTESRLAIRTDTILGRKVLEIEPRGAQALPPGGVLPVGQSTTPYQI
MLBr_02591|M.leprae_Br4923 TNRIGTASRLGIRTDTVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQS
:* : * *:** : * : . * * . : : :: .**:
MMAR_3866|M.marinum_M QAALKDATTTFEQVDSDRFAQSLTVLGRQLDKLPPVVPHAVANIDSLSSI
MUL_3798|M.ulcerans_Agy99 QAALKDATTTFEQVDSDRFAQSLTVLGRQLDKLPPVVPQAVANIDSLSSI
MAV_2386|M.avium_104 QAALQDATTTFEQVDSDRFAQSLAVLGKQLEGLPAVVPQAITNIDTLSSI
MAB_1008c|M.abscessus_ATCC_199 QATLRDATNTFDQVDFDKVAQSLSILGKQLDGLPEVVPQAMQNIQTLSQI
Mflv_0008|M.gilvum_PYR-GCK QEALTDVTTTFEQVDSDKFAETLSILGRQLQGMPEILPQALENTHTLSTI
Mvan_0961|M.vanbaalenii_PYR-1 QEALTDVATTFEQVDSDKFAESLAILGRQLQGLPEVVPQALQNTHTLSTI
MSMEG_1145|M.smegmatis_MC2_155 QEALTDVTTTFEKVDSDKFAETLQILGSQLETLPPVIPQALENTHTLSTI
TH_2869|M.thermoresistible__bu QEALADVATTYEQVDSDQFAESLAILGRQLETLPPVVPQALENTHTLSSI
Mb0177|M.bovis_AF2122/97 YDAFFDVTKAASGWDIETVKRSLNVLSETVDQTYPHLSAALDGVAKFSDT
Rv0171|M.tuberculosis_H37Rv YDAFFDVTKAASGWDIETVKRSLNVLSETVDQTYPHLSAALDGVAKFSDT
MLBr_02591|M.leprae_Br4923 YDAFFDATKVASGWNIDTIKQSLKVVSETIDQTYPHLSAALDGVAKFSDT
:: *.:.. . : : . .:* ::. :: :. *: . .:*
MMAR_3866|M.marinum_M IATRRDQLGQLLESTEQVTNTLRRQLSTIGGLVNQGQDLMGQFVARRAVF
MUL_3798|M.ulcerans_Agy99 IATRRDQLGQLLESTEQVTNTLRRQLSTIGGLVNQGQDLMGQFVARRAVF
MAV_2386|M.avium_104 IATRRDQLGQLLRSTEQVTNTLRRQQAGIGALVDQGQDLLGQFVARRAVF
MAB_1008c|M.abscessus_ATCC_199 IAERRDQLGTLLKSSEKVTNTLRHQQQGIGTLINQGQNLIGEFVVRRGTF
Mflv_0008|M.gilvum_PYR-GCK IADRRDQLGSLLETTEVVSNTLRRQQANIGSLVRQGNDLVGEFVLRRASF
Mvan_0961|M.vanbaalenii_PYR-1 LAQRRDQLGALLETTDVVSTTLKRQQSNIASMVRQGNDLVGEFVVRRASF
MSMEG_1145|M.smegmatis_MC2_155 IAQRRDQLGELLKTTELISNTLYRQKSTIGSLMNQSNSLLAEFVARRATF
TH_2869|M.thermoresistible__bu IAQRRDQLGELLKTTEMVSTTLRRQQANIGNLVHQGNSLLGEFVARRATF
Mb0177|M.bovis_AF2122/97 IGKRDEQITHLLAQANQVASILGDRSDQVDRLLVNAKTLIAAFNERGRAV
Rv0171|M.tuberculosis_H37Rv IGKRDEQITHLLAQANQVASILGDRSEQVDRLLVNAKTLIAAFNERGRAV
MLBr_02591|M.leprae_Br4923 IGARDKEIKHLIAQANQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAV
:. * .:: *: :: ::. * : : :: : : *:. * * .
MMAR_3866|M.marinum_M HAMMRSLDGFVGTL-RQIIGDRPGVDALLKDMREFTGLLAQHDDLLSNLL
MUL_3798|M.ulcerans_Agy99 HAMMRSLDGFVGTL-RQIIGDRPGVDALLKDMREFTGLLAQHDDLLSNLL
MAV_2386|M.avium_104 HAMMRSLSSLVDTLSRVVVNDRSGVDALLKDIRDFTGLVSAHDDLLHSLL
MAB_1008c|M.abscessus_ATCC_199 HAMMQSLTNLVQQLSKITIKDRPQLDEMLRTLHQLTDMLGQHDDLLRNIL
Mflv_0008|M.gilvum_PYR-GCK QAMMNAITNLVQTLGDIVIEDRPELEALLVNVRELSDMLGQHDDLLRSIL
Mvan_0961|M.vanbaalenii_PYR-1 HAMLAAITDLVQTLSDIVIGDRPELEALLVNVRELSDMLGQHDDLVRNIL
MSMEG_1145|M.smegmatis_MC2_155 HAMMDALTNLVQTLSGIVIDDRPELEKLVEDLRQLSSLLSKNDGMLRSIL
TH_2869|M.thermoresistible__bu HAMMDALTVLVQRLSDIVIDDRPELEELLSNLRELSGLLADNDGMLRSIL
Mb0177|M.bovis_AF2122/97 DALLGNISAFSAQVQNLIN-DNPNLNHVLEQLRILTDLLVDRKEDLAETL
Rv0171|M.tuberculosis_H37Rv DALLGNISAFSAQVQNLIN-DNPNLNHVLEQLRILTDLLVDRKEDLAETL
MLBr_02591|M.leprae_Br4923 DALLGNVAAFAAQVQRLIN-DNPNLNHVLEQLHQLSGILVQHKDDLANTL
.*:: : : : *.. :: :: :: ::.:: .. : . *
MMAR_3866|M.marinum_M QISPIFFREATNITGDG--NAVNFNAPNGLLLVDSWMCAISGR----AEQ
MUL_3798|M.ulcerans_Agy99 QISPIFFREATNITGDG--NAVNFNAPNGLLLVDSWMRAISGR----AEQ
MAV_2386|M.avium_104 QVSPIFFREAANLTGDG--NAINFNAPN-VPLIDSWMCAISGR----AKQ
MAB_1008c|M.abscessus_ATCC_199 QITPVTLRGVANATGTG--NAIEFNAPN-GLAVDSWMCAISGR----AKQ
Mflv_0008|M.gilvum_PYR-GCK QSGPPALRGLANATGMG--NAVEFNAAN-GLLVDSWMCAISGR----AKQ
Mvan_0961|M.vanbaalenii_PYR-1 QSGPLALRGLANATGSG--NAVDFNAAN-GLLVDSWMCAISGR----AKQ
MSMEG_1145|M.smegmatis_MC2_155 QTAPIALRNIANMTGTG--NAIDFNSSS-GLLVDSWMCAISGR----AKQ
TH_2869|M.thermoresistible__bu QTTPIAVRNLANITGTG--NAIDFNAPG-GLLVDSWMCAISGR----AKQ
Mb0177|M.bovis_AF2122/97 TILGRFSASFGETFASGPYFKVLLANLVPGQILQPFVDAAFKKRGISPED
Rv0171|M.tuberculosis_H37Rv TILGRFSASFGETFASGPYFKVLLANLVPGQILQPFVDAAFKKRGISPED
MLBr_02591|M.leprae_Br4923 IQVAAFLPSLNEAIGSGPFFKVVLHNLAPYQILQPWVDAAFKKRGIDPEN
: . * : : ::.:: * : .::
MMAR_3866|M.marinum_M FGMIPYFKDCK---------------------------------------
MUL_3798|M.ulcerans_Agy99 FGMIPYFKDCK---------------------------------------
MAV_2386|M.avium_104 FGMIQYFKDCK---------------------------------------
MAB_1008c|M.abscessus_ATCC_199 FGMIQYFKDCK---------------------------------------
Mflv_0008|M.gilvum_PYR-GCK FGMIQYFQDCK---------------------------------------
Mvan_0961|M.vanbaalenii_PYR-1 FGMIEYLKDCK---------------------------------------
MSMEG_1145|M.smegmatis_MC2_155 FGMIQYFQDCK---------------------------------------
TH_2869|M.thermoresistible__bu FGMIEYFQDCK---------------------------------------
Mb0177|M.bovis_AF2122/97 FWRSAGLPAYRWPDPNGTRFPNGAPPPPPPVLEGTPEHPGPAVPPGSPCS
Rv0171|M.tuberculosis_H37Rv FWRSAGLPAYRWPDPNGTRFPNGAPPPPPPVLEGTPEHPGPAVPPGSPCS
MLBr_02591|M.leprae_Br4923 FWRSAGLPEFRFPDPNGTRFPNGAPPPAPPVLEGTPENPGPAVPPGSPCS
* : :
MMAR_3866|M.marinum_M --------------------------------------------------
MUL_3798|M.ulcerans_Agy99 --------------------------------------------------
MAV_2386|M.avium_104 --------------------------------------------------
MAB_1008c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0008|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0961|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1145|M.smegmatis_MC2_155 --------------------------------------------------
TH_2869|M.thermoresistible__bu --------------------------------------------------
Mb0177|M.bovis_AF2122/97 YTPPADG----------LPRPWDPLPCANLTQGPFGGPDFPAPLDVATSP
Rv0171|M.tuberculosis_H37Rv YTPPADG----------LPRPWDPLPCANLTQGPFGGPDFPAPLDVATSP
MLBr_02591|M.leprae_Br4923 YTPAHPGGNNTIGDEMGLPRPWNPLPCAGATAGPYGGPAFPAPIDVQTSP
MMAR_3866|M.marinum_M --------------------------------------------------
MUL_3798|M.ulcerans_Agy99 --------------------------------------------------
MAV_2386|M.avium_104 --------------------------------------------------
MAB_1008c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0008|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0961|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1145|M.smegmatis_MC2_155 --------------------------------------------------
TH_2869|M.thermoresistible__bu --------------------------------------------------
Mb0177|M.bovis_AF2122/97 PNPDGPPPAPGLPIAGRPGEVPPNVPGTPVPIPQEAPPGARTLPLGPAPG
Rv0171|M.tuberculosis_H37Rv PNPDGPPPAPGLPIAGRPGEVPPNVPGTPVPIPQEAPPGARTLPLGPAPG
MLBr_02591|M.leprae_Br4923 PNPDGLPLLPGIAIAGRPGDPAPNVPGTPVPLPPNAPPGARTEQLAPA--
MMAR_3866|M.marinum_M -----------------------------------------
MUL_3798|M.ulcerans_Agy99 -----------------------------------------
MAV_2386|M.avium_104 -----------------------------------------
MAB_1008c|M.abscessus_ATCC_199 -----------------------------------------
Mflv_0008|M.gilvum_PYR-GCK -----------------------------------------
Mvan_0961|M.vanbaalenii_PYR-1 -----------------------------------------
MSMEG_1145|M.smegmatis_MC2_155 -----------------------------------------
TH_2869|M.thermoresistible__bu -----------------------------------------
Mb0177|M.bovis_AF2122/97 PAPPPAAPGPPAPPGPGPQLPAPFINPGGTGGSGVTGGSEN
Rv0171|M.tuberculosis_H37Rv PAPPPAAPGPPAPPGPGPQLPAPFINPGGTGGSGVTGGSEN
MLBr_02591|M.leprae_Br4923 -AP---AQDSSAPHEPREQLSAPLINPGGTGGSGGAGGSRN