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M. thermoresistible (build 8) TH_2869 (-)

annotation: virulence factor Mce family protein
coordinates: 4665874 - 4666878
length: 335

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2869--100% (335)virulence factor Mce family protein
M. thermoresistible (build 8)TH_3264-7e-3232.26% (279) PUTATIVE virulence factor Mce family protein
M. thermoresistible (build 8)TH_1935-2e-3129.24% (301) MCE-FAMILY PROTEIN MCE4C

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3527cmce4C5e-3027.71% (314) MCE-family protein MCE4C
M. gilvum PYR-GCKMflv_0008-1e-13973.35% (334) virulence factor Mce family protein
M. tuberculosis H37RvRv3497cmce4C5e-3027.71% (314) MCE-family protein MCE4C
M. leprae Br4923MLBr_02591mce1C2e-2426.40% (303) putative secreted protein
M. abscessus ATCC 19977MAB_1008c-1e-12363.47% (334) putative MCE family protein
M. marinum MMMAR_3866mce5C1e-11964.48% (335) Mce family protein, Mce5C
M. avium 104MAV_2386-1e-12265.57% (334) virulence factor Mce family protein
M. smegmatis MC2 155MSMEG_1145-1e-14676.65% (334) virulence factor Mce family protein
M. ulcerans Agy99MUL_3798mce5C1e-11764.18% (335) Mce family protein, Mce5C
M. vanbaalenii PYR-1Mvan_0961-1e-13972.75% (334) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_2869|M.thermoresistible__bu      -----------------LETYSRTTLGVIAVAVVAVLVGALLVVKAAGIG
MSMEG_1145|M.smegmatis_MC2_155      -----MAEARKARRRKPLESYNRLWLGVVAVAVVSVLIGAMLLVRVADIG
Mflv_0008|M.gilvum_PYR-GCK          -----MAEQTK-RRRRRLESYHKAWLGTVAVVVVAVLVGALLLIKAADVG
Mvan_0961|M.vanbaalenii_PYR-1       -----MAERRK-WPRRPLESYHSAWLGFAAVAVVAVLIGAMLLIKGADVG
MMAR_3866|M.marinum_M               MADSSLRQRLSALQRRPLESYNKTWLGFAAVAVVAVVIAAMLVVHLAGAG
MUL_3798|M.ulcerans_Agy99           MADSSLRHRLSALQRRPLESYNKTWLRFAAVAVVAVVIAAMLVVHLAGAG
MAV_2386|M.avium_104                -----MRQRLSALTKRPLESYNKTWLGFVAVAVVAAVIAVMLVVHALGAG
MAB_1008c|M.abscessus_ATCC_199      MAE---QSRWQKIKSRPVETYNKTWLGFIAIAVIGALVGGMLLVKAIGFG
Mb3527c|M.bovis_AF2122/97           ------MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQG
Rv3497c|M.tuberculosis_H37Rv        ------MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQG
MLBr_02591|M.leprae_Br4923          -----------MRTLELPNRLRSGLIGVLVVLLIIGVGQSFTSVPILFAR
                                                      :      :    :  :  :      :      

TH_2869|M.thermoresistible__bu      YKEYTARFLQAAALQPGNPITVAGIPVGEVLSMKLNGDHVEARLKVRGDI
MSMEG_1145|M.smegmatis_MC2_155      YTQYTARFLQAAALKAGNPVTVAGIPVGEVKSMRLAGDHVEAKIKVRNDV
Mflv_0008|M.gilvum_PYR-GCK          YRTFTAQFLQAAALQPGNPVSVAGIPVGEVTDMKLAGDHVEARFTVRNDV
Mvan_0961|M.vanbaalenii_PYR-1       YRKYTAQFLQAAALQPGNPVTVAGIPVGEVTGMELAGDHVVADFTVRNDV
MMAR_3866|M.marinum_M               YRRYTAEFLQAAALRAGNPIAIAGIPVGTVTSMKLVGDHVEAGLRIRDDV
MUL_3798|M.ulcerans_Agy99           YRRYTAEFLQAAALRAGNPIAIAGIPVGTVTSMKLVGDHVEAGLRIRDDV
MAV_2386|M.avium_104                YRHYTAEFAQAASLRAGNPIVVAGIPVGTVTSMKLVGDHVEAGLKVRDNI
MAB_1008c|M.abscessus_ATCC_199      YTTYTAEFAQAASLRAGQPITVAGIPMGTVTSMKLVGDHVEAKLSVSDDV
Mb3527c|M.bovis_AF2122/97           -KTYDAYFTDAGGITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRSI
Rv3497c|M.tuberculosis_H37Rv        -KTYDAYFTDAGGITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRSI
MLBr_02591|M.leprae_Br4923          -PSYYGQFTDTGGLNKGDKVRIAGMDVGKVEALKIDGDHVVIKFSIG-TN
                                       : . * ::..:  *: : ::*: :* *  : : *: .   : :    

TH_2869|M.thermoresistible__bu      RLGEHSRAVIKITTILGSRYLALYPDGPGTL-PDNTFDLKHTEVPYDLQE
MSMEG_1145|M.smegmatis_MC2_155      GLGKDSRAKIMVTTILGSRYLSLEPAGDGTL-PDRTFDLSHTDVPYDLQE
Mflv_0008|M.gilvum_PYR-GCK          DLGEDSRAVIKVTTILGSRYLSLEPEGTGAL-PDRHFDLSHTEVPYDLQE
Mvan_0961|M.vanbaalenii_PYR-1       ALGEDSRAVIKVTTILGSRYLSLEPEGPGSL-PDRRFDLAHTEVPYDLQE
MMAR_3866|M.marinum_M               VLGKDSTATIRVTTILGSRYLAIEPDGAASL-PDHTFDLAHTAVPYDLQA
MUL_3798|M.ulcerans_Agy99           VLGKDSTATIRVTTILGSRYLAIEPDGAASL-PDHTFDLAHTAVPYDLQA
MAV_2386|M.avium_104                SFGKDSRAQIRVTTILGSRYLALEPNGPARL-PGNTFDLAHTEVPYDLQA
MAB_1008c|M.abscessus_ATCC_199      KLGKDTKAAIRVTTILGSRYLDLQPEGPGSL-PNKTIDLAHTEVPYDLQA
Mb3527c|M.bovis_AF2122/97           VVGDQSLAAIRTDTILGERSIAVSPAGSG---KSTTIPLSRTTTPYTLNG
Rv3497c|M.tuberculosis_H37Rv        VVGDQSLAAIRTDTILGERSIAVSPAGSG---KSTTIPLSRTTTPYTLNG
MLBr_02591|M.leprae_Br4923          RIGTASRLGIRTDTVLGKKVLEVETRGTQLLRPGDSLPLGQSTTPYQSYD
                                     .*  :   *   *:**.: : : . *      .  : * :: .**    

TH_2869|M.thermoresistible__bu      ALADVATTYEQVDSDQFAESLAILGRQLETLPPVVPQALENTHTLSSIIA
MSMEG_1145|M.smegmatis_MC2_155      ALTDVTTTFEKVDSDKFAETLQILGSQLETLPPVIPQALENTHTLSTIIA
Mflv_0008|M.gilvum_PYR-GCK          ALTDVTTTFEQVDSDKFAETLSILGRQLQGMPEILPQALENTHTLSTIIA
Mvan_0961|M.vanbaalenii_PYR-1       ALTDVATTFEQVDSDKFAESLAILGRQLQGLPEVVPQALQNTHTLSTILA
MMAR_3866|M.marinum_M               ALKDATTTFEQVDSDRFAQSLTVLGRQLDKLPPVVPHAVANIDSLSSIIA
MUL_3798|M.ulcerans_Agy99           ALKDATTTFEQVDSDRFAQSLTVLGRQLDKLPPVVPQAVANIDSLSSIIA
MAV_2386|M.avium_104                ALQDATTTFEQVDSDRFAQSLAVLGKQLEGLPAVVPQAITNIDTLSSIIA
MAB_1008c|M.abscessus_ATCC_199      TLRDATNTFDQVDFDKVAQSLSILGKQLDGLPEVVPQAMQNIQTLSQIIA
Mb3527c|M.bovis_AF2122/97           VLQDLGRNANDLNRPQFEQALNVFTQALHDATPQVRGAVDGLTSLSRALN
Rv3497c|M.tuberculosis_H37Rv        VLQDLGRNANDLNRPQFEQALNVFTQALHDATPQVRGAVDGLTSLSRALN
MLBr_02591|M.leprae_Br4923          AFFDATKVASGWNIDTIKQSLKVVSETIDQTYPHLSAALDGVAKFSDTIG
                                    .: *     .  :   . ::* :.   :.     :  *: .  .:*  : 

TH_2869|M.thermoresistible__bu      QRRDQLGELLKTTEMVSTTLRRQQANIGNLVHQGNSLLGEFVARRATFHA
MSMEG_1145|M.smegmatis_MC2_155      QRRDQLGELLKTTELISNTLYRQKSTIGSLMNQSNSLLAEFVARRATFHA
Mflv_0008|M.gilvum_PYR-GCK          DRRDQLGSLLETTEVVSNTLRRQQANIGSLVRQGNDLVGEFVLRRASFQA
Mvan_0961|M.vanbaalenii_PYR-1       QRRDQLGALLETTDVVSTTLKRQQSNIASMVRQGNDLVGEFVVRRASFHA
MMAR_3866|M.marinum_M               TRRDQLGQLLESTEQVTNTLRRQLSTIGGLVNQGQDLMGQFVARRAVFHA
MUL_3798|M.ulcerans_Agy99           TRRDQLGQLLESTEQVTNTLRRQLSTIGGLVNQGQDLMGQFVARRAVFHA
MAV_2386|M.avium_104                TRRDQLGQLLRSTEQVTNTLRRQQAGIGALVDQGQDLLGQFVARRAVFHA
MAB_1008c|M.abscessus_ATCC_199      ERRDQLGTLLKSSEKVTNTLRHQQQGIGTLINQGQNLIGEFVVRRGTFHA
Mb3527c|M.bovis_AF2122/97           RRDEALQGLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAALSA
Rv3497c|M.tuberculosis_H37Rv        RRDEALQGLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAALSA
MLBr_02591|M.leprae_Br4923          ARDKEIKHLIAQANQVASVLGDRGAQVDRLLVNTKTLIAAFNERGRAVDA
                                     * . :  *:  :. ::..*  :   :  :: : : *.. :  *   . *

TH_2869|M.thermoresistible__bu      MMDALTVLVQRLSDIVIDDRPELEELLSNLRELSGLLADNDGMLRSILQT
MSMEG_1145|M.smegmatis_MC2_155      MMDALTNLVQTLSGIVIDDRPELEKLVEDLRQLSSLLSKNDGMLRSILQT
Mflv_0008|M.gilvum_PYR-GCK          MMNAITNLVQTLGDIVIEDRPELEALLVNVRELSDMLGQHDDLLRSILQS
Mvan_0961|M.vanbaalenii_PYR-1       MLAAITDLVQTLSDIVIGDRPELEALLVNVRELSDMLGQHDDLVRNILQS
MMAR_3866|M.marinum_M               MMRSLDGFVGTL-RQIIGDRPGVDALLKDMREFTGLLAQHDDLLSNLLQI
MUL_3798|M.ulcerans_Agy99           MMRSLDGFVGTL-RQIIGDRPGVDALLKDMREFTGLLAQHDDLLSNLLQI
MAV_2386|M.avium_104                MMRSLSSLVDTLSRVVVNDRSGVDALLKDIRDFTGLVSAHDDLLHSLLQV
MAB_1008c|M.abscessus_ATCC_199      MMQSLTNLVQQLSKITIKDRPQLDEMLRTLHQLTDMLGQHDDLLRNILQI
Mb3527c|M.bovis_AF2122/97           LISGIDDVAAQISGFVADNRKEFGPALSKLNLVLANLNERRDYITEALKR
Rv3497c|M.tuberculosis_H37Rv        LISGIDDVAAQISGFVADNRKEFGPALSKLNLVLANLNERRDYITEALKR
MLBr_02591|M.leprae_Br4923          LLGNVAAFAAQVQRLINDN-PNLNHVLEQLHQLSGILVQHKDDLANTLIQ
                                    ::  :  ..  :      :   .   :  :. .   :  . . : . *  

TH_2869|M.thermoresistible__bu      TPIAVRNLANITGTGNAIDFNAPG---GLLVDSWMCAISGR---------
MSMEG_1145|M.smegmatis_MC2_155      APIALRNIANMTGTGNAIDFNSSS---GLLVDSWMCAISGR---------
Mflv_0008|M.gilvum_PYR-GCK          GPPALRGLANATGMGNAVEFNAAN---GLLVDSWMCAISGR---------
Mvan_0961|M.vanbaalenii_PYR-1       GPLALRGLANATGSGNAVDFNAAN---GLLVDSWMCAISGR---------
MMAR_3866|M.marinum_M               SPIFFREATNITGDGNAVNFNAPNG--LLLVDSWMCAISGR---------
MUL_3798|M.ulcerans_Agy99           SPIFFREATNITGDGNAVNFNAPNG--LLLVDSWMRAISGR---------
MAV_2386|M.avium_104                SPIFFREAANLTGDGNAINFNAPN---VPLIDSWMCAISGR---------
MAB_1008c|M.abscessus_ATCC_199      TPVTLRGVANATGTGNAIEFNAPN---GLAVDSWMCAISGR---------
Mb3527c|M.bovis_AF2122/97           LPTYATTLGEVVGSGPGFNVNVYS----VLPGPLVATVFDL---------
Rv3497c|M.tuberculosis_H37Rv        LPTYATTLGEVVGSGPGFNVNVYS----VLPGPLVATVFDL---------
MLBr_02591|M.leprae_Br4923          VAAFLPSLNEAIGSGPFFKVVLHNLAPYQILQPWVDAAFKKRGIDPENFW
                                     .       :  * *  ...   .        . : :             

TH_2869|M.thermoresistible__bu      ----AKQFG-----MIEYFQDCK---------------------------
MSMEG_1145|M.smegmatis_MC2_155      ----AKQFG-----MIQYFQDCK---------------------------
Mflv_0008|M.gilvum_PYR-GCK          ----AKQFG-----MIQYFQDCK---------------------------
Mvan_0961|M.vanbaalenii_PYR-1       ----AKQFG-----MIEYLKDCK---------------------------
MMAR_3866|M.marinum_M               ----AEQFG-----MIPYFKDCK---------------------------
MUL_3798|M.ulcerans_Agy99           ----AEQFG-----MIPYFKDCK---------------------------
MAV_2386|M.avium_104                ----AKQFG-----MIQYFKDCK---------------------------
MAB_1008c|M.abscessus_ATCC_199      ----AKQFG-----MIQYFKDCK---------------------------
Mb3527c|M.bovis_AF2122/97           ----VFQPGKLPDSLADYLRGFIQERWIIRPKSP----------------
Rv3497c|M.tuberculosis_H37Rv        ----VFQPGKLPDSLADYLRGFIQERWIIRPKSP----------------
MLBr_02591|M.leprae_Br4923          RSAGLPEFRFPDPNGTRFPNGAPPPAPPVLEGTPENPGPAVPPGSPCSYT
                                          :          : ..                             

TH_2869|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1145|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0008|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0961|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3866|M.marinum_M               --------------------------------------------------
MUL_3798|M.ulcerans_Agy99           --------------------------------------------------
MAV_2386|M.avium_104                --------------------------------------------------
MAB_1008c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3527c|M.bovis_AF2122/97           --------------------------------------------------
Rv3497c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_02591|M.leprae_Br4923          PAHPGGNNTIGDEMGLPRPWNPLPCAGATAGPYGGPAFPAPIDVQTSPPN
                                                                                      

TH_2869|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1145|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0008|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0961|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3866|M.marinum_M               --------------------------------------------------
MUL_3798|M.ulcerans_Agy99           --------------------------------------------------
MAV_2386|M.avium_104                --------------------------------------------------
MAB_1008c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3527c|M.bovis_AF2122/97           --------------------------------------------------
Rv3497c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_02591|M.leprae_Br4923          PDGLPLLPGIAIAGRPGDPAPNVPGTPVPLPPNAPPGARTEQLAPAAPAQ
                                                                                      

TH_2869|M.thermoresistible__bu      ---------------------------------
MSMEG_1145|M.smegmatis_MC2_155      ---------------------------------
Mflv_0008|M.gilvum_PYR-GCK          ---------------------------------
Mvan_0961|M.vanbaalenii_PYR-1       ---------------------------------
MMAR_3866|M.marinum_M               ---------------------------------
MUL_3798|M.ulcerans_Agy99           ---------------------------------
MAV_2386|M.avium_104                ---------------------------------
MAB_1008c|M.abscessus_ATCC_199      ---------------------------------
Mb3527c|M.bovis_AF2122/97           ---------------------------------
Rv3497c|M.tuberculosis_H37Rv        ---------------------------------
MLBr_02591|M.leprae_Br4923          DSSAPHEPREQLSAPLINPGGTGGSGGAGGSRN