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SNGAYTAVEKTRSRDIRVVVIGAGMSGLCMASTLRHRGITNFTVYEKADEVGGTWRDNTYPGLQCDVPSR YYSYSFAPNPRWSKGFSPGSEIHQYFVRFTDQQDLRRNIRFGTAVTRAEWVDEPGQSHWELELSDGGRDI ADVVVGATGVLHLPRLPEIEGLQSFAGPCFHSARWDHSVPYIGKRVGLIGTGSSGVQIIGALAEQVQHLS VFQRSAQWVAPVPNFTYSALSKSIWSRIPVLNRISYLLWRFYFERGVGGSVVIPGARRKLIQGFVRASHR LLIRDATLREKLHPDYEPLCRRLVMSVPFFKAVQRPNVSVLTGGIDRVVPQGVITNDGVLHELDILVCAT GFDAHSYLRPMEVLGRDGIKLSDAWSDGPRAYRAVGLAGFPNFFLLIGPNSPIGNNSLISIAETQVKFAM HWIDEIRSGRMQSVAPTAHAAETFNTQMRRAMPNTVWSTGCDSWYLGADGVPELWPWPPVDYRRTLTSPI RGDFAIT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0522c | - | - | 100% (498) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_1527 | - | e-114 | 43.20% (493) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_4476c | - | 2e-92 | 37.01% (481) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0916 | - | 1e-143 | 50.11% (471) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4608 | - | 5e-93 | 37.94% (485) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv0892 | - | 1e-143 | 50.11% (471) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-27 | 24.81% (395) | putative monooxygenase |
| M. marinum M | MMAR_4641 | - | 1e-144 | 49.79% (476) | monooxygenase |
| M. avium 104 | MAV_3915 | - | 1e-92 | 38.38% (456) | flavin-containing monooxygenase FMO |
| M. smegmatis MC2 155 | MSMEG_2310 | - | 4e-97 | 39.53% (473) | monooxygenase |
| M. thermoresistible (build 8) | TH_4080 | - | 2e-91 | 37.37% (463) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0256 | - | 1e-140 | 48.74% (476) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_3427 | - | 1e-148 | 52.39% (481) | putative monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3915|M.avium_104 MTDVVTHTETAPTPAAKAAKP-VHTRAVIIGTGFSGLGMAIALQKQGVG-
TH_4080|M.thermoresistible__bu MT--VTEPSADITPANTPTQPPVRTRALIVGTGFSGLGMAIALQRRGID-
MSMEG_2310|M.smegmatis_MC2_155 --------------MTAADQQPIRTRALVIGTGFSGLGMAIELQRRGVD-
Mflv_4608|M.gilvum_PYR-GCK --------------------MSDTTTVLIVGAGFAGLGTAIRLLQQGIDD
Mb0916|M.bovis_AF2122/97 --------MTG-----------RCPTVAVVGAGMSGMCVAITLLSAGITD
Rv0892|M.tuberculosis_H37Rv --------MTG-----------RCPTVAVVGAGMSGMCVAITLLSAGITD
MMAR_4641|M.marinum_M --------MTR-----------RDPSVAIVGAGMAGICMAITLLNSGITD
MUL_0256|M.ulcerans_Agy99 --------MTR-----------RDPSVAIVGAAMAGICMAITLLNSGITD
MAB_0522c|M.abscessus_ATCC_199 --------MSNGAYTAVEKTRSRDIRVVVIGAGMSGLCMASTLRHRGITN
Mvan_3427|M.vanbaalenii_PYR-1 --------MG--------------IRVAIIGAGMSGLCMAAKLQDAGIED
MLBr_00065|M.leprae_Br4923 ---------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNK
. ::*:.::*: * *
MAV_3915|M.avium_104 -FVILEKADDIGGTWRDNSYPGCACDIPSHLYSFSFEPKPDWKNPFSYQP
TH_4080|M.thermoresistible__bu -FLMLEKADDIGGTWRDNTYPGCACDIPSHLYSFSFEPKADWRHLFSYQD
MSMEG_2310|M.smegmatis_MC2_155 -FLILEKADEIGGTWRDNTYPGCACDIPSHMYSFSFEPKADWKHMWSFQP
Mflv_4608|M.gilvum_PYR-GCK -FVVLERADEVGGTWRDNTYPGAACDIPSLLYSYGFEQNPDWSRAYSGSA
Mb0916|M.bovis_AF2122/97 -VCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGG
Rv0892|M.tuberculosis_H37Rv -VCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGG
MMAR_4641|M.marinum_M -VTIYEKADEVGGTWRENTYPGLVCDVPSRLYQYSFAKNPDWSNLFSPGG
MUL_0256|M.ulcerans_Agy99 -VTIYEKADEVGGTWRENTYPGLVCDVPSRLYHYSFAKNPDWSNLFSPGG
MAB_0522c|M.abscessus_ATCC_199 -FTVYEKADEVGGTWRDNTYPGLQCDVPSRYYSYSFAPNPRWSKGFSPGS
Mvan_3427|M.vanbaalenii_PYR-1 -FTVFEKADEVGGTWRDNTYPGLACDVPSRYYAYSFRPNPEWSHMMPPGP
MLBr_00065|M.leprae_Br4923 SYVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTKCQAIAD-GK
: *: :**** *** .* : * .
MAV_3915|M.avium_104 EIWDYLKGVTEKYGLRRYIEFNSLVDRAHWDDD--EHRWHVFTT---DGR
TH_4080|M.thermoresistible__bu EIQEYLQGVTAKYGLRRYIHFDSLVDRAHWDDT--EHRWHVFTA---DGR
MSMEG_2310|M.smegmatis_MC2_155 EIQDYLLGVTAKYGLRRHIHFNSHVDRAHWDDE--ELRWHVFTK---TGQ
Mflv_4608|M.gilvum_PYR-GCK EILGYIKTMVDKYSLSRFIRFGVNVTGLEFDEE--SALWTAQTA---DGS
Mb0916|M.bovis_AF2122/97 EIQDYLRGIAERYGLRHRIRFGATVVSARFDD----GRWVLRTD---SGT
Rv0892|M.tuberculosis_H37Rv EIQDYLRGIAERYGLRHRIRFGATVVSARFDD----GRWVLRTD---SGT
MMAR_4641|M.marinum_M EIQSYFCGIADRYRLRDRIRFGTEIVSARFED----DHWSVVTD---SGE
MUL_0256|M.ulcerans_Agy99 EIQSYFCGIADRYRLRDRIRFGTEIVSARFED----DHWSVVTD---SGE
MAB_0522c|M.abscessus_ATCC_199 EIHQYFVRFTDQQDLRRNIRFGTAVTRAEWVDEPGQSHWELELS---DGG
Mvan_3427|M.vanbaalenii_PYR-1 EVFRYFRQFATERGIRRHIRFGADVTAARFRD----GKWWLTSP---AGD
MLBr_00065|M.leprae_Br4923 PILEYIKSTAVMHGIDKYIRLNHKVTGADWSS--IENRWTVQVENNGTPR
: *: . : *.:. : : . *
MAV_3915|M.avium_104 EYVAQFLISGAGALHIPS--LPDIEGRDEFAGPAFHSAEWDHTVDLTGKR
TH_4080|M.thermoresistible__bu EYIAQFLISCAGALHIPS--IPDFPGRDQFAGPAFHSAQWDHSVDLTGKR
MSMEG_2310|M.smegmatis_MC2_155 EYIAQFLVSGAGGLHIPQ--IPDIEGRESFAGAAFHSAQWDHSVDLRGKR
Mflv_4608|M.gilvum_PYR-GCK QFTARTAVMASGPLANAS--LPDIRGLDTFDGHKIHSARWDHDYDMSDKR
Mb0916|M.bovis_AF2122/97 ESTVDFLISATGVLHHPR--IPPIAGLDDFRGTVFHSARWDHTVPLLGRR
Rv0892|M.tuberculosis_H37Rv ESTVDFLISATGVLHHPR--IPPIAGLDDFRGTVFHSARWDHTVPLLGRR
MMAR_4641|M.marinum_M ETAVDFLIVATGLLHHPR--VPAIAGLDDFGGSAFHSARWDHRVAVQGQR
MUL_0256|M.ulcerans_Agy99 ETAVDFLIVATGLLHHPR--VPAIAGLDDFGGSAFHSARWDQRVAVQGRR
MAB_0522c|M.abscessus_ATCC_199 RDIADVVVGATGVLHLPR--LPEIEGLQSFAGPCFHSARWDHSVPYIGKR
Mvan_3427|M.vanbaalenii_PYR-1 -EEFDVLVTATGFLRVPR--YPDILGLDTFTGPMFHSSRWDHSVSLSDKR
MLBr_00065|M.leprae_Br4923 MISCSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKN
. :* * : * : * * :*. .* . :.
MAV_3915|M.avium_104 VAVIGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRSNPEIPPAVRAA
TH_4080|M.thermoresistible__bu VAVIGTGASAIQIVPEIIDR-VAQLQLYQRTPAWVVPRTNDELPAWLRRA
MSMEG_2310|M.smegmatis_MC2_155 VAVIGTGASAIQIVPEIVKD-VAELHLYQRTPAWVMPRVNNAFPQWLRNV
Mflv_4608|M.gilvum_PYR-GCK VAVIGTGASAVQIIPELVKT-ARSVKVFQRTPGWVLPRPDFSHPQWVRTA
Mb0916|M.bovis_AF2122/97 IAVIGTGSTGVQLVCGLAGV-AGKVTMFQRTAQWVLPWPNPRYSKLARVF
Rv0892|M.tuberculosis_H37Rv IAVIGTGSTGVQLVCGLAGV-AGKVTMFQRTAQWVLPWPNPRYSKLARVF
MMAR_4641|M.marinum_M VAVIGSGSTGVQLVSALAGV-AAKVTMFQRTPQWILPWPNRQYSKVSRAC
MUL_0256|M.ulcerans_Agy99 VAVIGSGSTGVQLVSALAGV-AAKVTMFQRTRQWILLWPNRQYSKVSRAC
MAB_0522c|M.abscessus_ATCC_199 VGLIGTGSSGVQIIGALAEQ-VQHLSVFQRSAQWVAPVPNFTYSALSKSI
Mvan_3427|M.vanbaalenii_PYR-1 IGLIGTGSTGVQITSALGGN-VRHLKVFQRTPQWICPWPNLRVSEHTKAA
MLBr_00065|M.leprae_Br4923 IVVIGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQP--AKDKIAARL
: :**:*::.: : : . : : **: ::
MAV_3915|M.avium_104 MENVPGLRALVRLAIYWGQEA-LAFGMTKRPNLLKVIEAYAKYNIRRSVK
TH_4080|M.thermoresistible__bu LENIPGLRLALRGGIYALQEA-LAVGMTKYPGMLRIGHLLGKWNINRSVK
MSMEG_2310|M.smegmatis_MC2_155 FSYVPGTRALLRAAIYWIHEG-VGFAMTKEPRLLKIGEWMGRYNINRSIK
Mflv_4608|M.gilvum_PYR-GCK FRRLPRVQNVGRQAWFWGHEL-MAVGMVWDTPVTTGIQLLAKANLRRQVS
Mb0916|M.bovis_AF2122/97 HRAFPCLGSLAYKAYSLSFET-FAVALSNPGLHRKLVGAVCRASLRR-VR
Rv0892|M.tuberculosis_H37Rv HRAFPCLGSLAYKAYSLSFET-FAVALSNPGLHRKLVGAVCRASLRR-VR
MMAR_4641|M.marinum_M YRGAPWLESLAYKIWGRAFEQ-FTAALTRPGWHRRVTGMTCRASLRL-VR
MUL_0256|M.ulcerans_Agy99 YRGAPWLESLAYKIWGRAFEQ-FTAALTRPGWHRRVTGMTCRASLRL-VR
MAB_0522c|M.abscessus_ATCC_199 WSRIPVLNRISYLLWRFYFERGVGGSVVIPGARRKLIQGFVRASHRLLIR
Mvan_3427|M.vanbaalenii_PYR-1 MRRWTWLNSFGYWFWGGFVRSIFGVAPVRPGWQRWLYQTQCHWNLRLSVR
MLBr_00065|M.leprae_Br4923 NRWLPDKYAYTAVRWKNILRQ-SALYGACQKWPQRMRNILLGHVARRLPK
. . .
MAV_3915|M.avium_104 DKELRRKLTPHYRIGCKRILNS--STYYGAVADPKTELVTDHIARITPDG
TH_4080|M.thermoresistible__bu DPQLRAKLTPDYRLGCKRILNS--STYYPAVADPRTEVITESIDRITTDG
MSMEG_2310|M.smegmatis_MC2_155 DPELRRKLTPSYRAGCKRILNS--DTYYRGIADPKTQVITEGIARMTPTG
Mflv_4608|M.gilvum_PYR-GCK DTWLRRQLTPNFRAGCKRMLMS--SDYYPALQRDNCKLVSWPIATLSPNG
Mb0916|M.bovis_AF2122/97 DPRLRRALTPDYEPMCKRLVMS--GGFYRAIQRDDVELVTAGIDHVEHRG
Rv0892|M.tuberculosis_H37Rv DPRLRRALTPDYEPMCKRLVMS--GGFYRAIQRDDVELVTAGIDHVEHRG
MMAR_4641|M.marinum_M DPHLRQALTPDYQPMCKRLVMS--SGFYRAIQRDDVELVTTGIDRIENAG
MUL_0256|M.ulcerans_Agy99 DPHLRQALTPDYQPMCKRLVMS--SGFYRAIQRDDVELVTTGIDRIENAG
MAB_0522c|M.abscessus_ATCC_199 DATLREKLHPDYEPLCRRLVMS--VPFFKAVQRPNVSVLTGGIDRVVPQG
Mvan_3427|M.vanbaalenii_PYR-1 DKELKKKLTPPDQPMCKRMIFA--GHYYRTVQRPDVEIVTDPIVEVQPRG
MLBr_00065|M.leprae_Br4923 GYDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDRFTSTG
. :: : * . :*: : : .::: * . *
MAV_3915|M.avium_104 IVTADGTHRPVDVIVYATGFHVTDSYTYVQIKGLHGEDLVDRWNREGIGA
TH_4080|M.thermoresistible__bu IVTSDGTERAVDVIVYATGFHVSDSYKYVQIKGLNGEDIVDRFNREGPMA
MSMEG_2310|M.smegmatis_MC2_155 IVTNDGVEHPVDIVVYATGFHVTDSYTYVDIKGAGGEDLVDRWNREGIQA
Mflv_4608|M.gilvum_PYR-GCK IRTADGIEHELDCIVFATGFDVCKAGTPFPIRGAHGRELSDEWS-QGAYA
Mb0916|M.bovis_AF2122/97 IVTDDGVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQ-DGPHA
Rv0892|M.tuberculosis_H37Rv IVTDDGVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQ-DGPHA
MMAR_4641|M.marinum_M IVTDDGVLREVDVIVLATGFDSHAFFRPMKLIGRDGVEIDELWR-GGPYA
MUL_0256|M.ulcerans_Agy99 IVTDDGVLREVDVIVLATGFDSHAFFRPMKLIGRDGVEIDELWR-GGPYA
MAB_0522c|M.abscessus_ATCC_199 VITNDGVLHELDILVCATGFDAHSYLRPMEVLGRDGIKLSDAWS-DGPRA
Mvan_3427|M.vanbaalenii_PYR-1 VVTADGTLHEVDLLALATGFDFHAYVRPLTITGEHGRTLDDAWA-DGPTA
MLBr_00065|M.leprae_Br4923 IRLKSGNELRADIIVTATGLNLQLFGGAVATVDGQPVDLAQTMS------
: .* * :. ***:. . . : :
MAV_3915|M.avium_104 HRGITVADVPNLFFLLGPNTGLGHNSVVFMIESQIRYVADAIATCDKLGA
TH_4080|M.thermoresistible__bu HRGTAVADLPNAYLLLGPNTGLGHNSMVYMIESQINYVIEAIKAVDKAGA
MSMEG_2310|M.smegmatis_MC2_155 HRGVAVAGMPNLFFLLGPNTALGHNSVVFMIEQQIRYVGQAIAAVDKAGA
Mflv_4608|M.gilvum_PYR-GCK YRSVTVAGYPNLFFTFGPNSGPGHNSALVYMEAEINYIVKAIGAIIANDL
Mb0916|M.bovis_AF2122/97 HQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGEF
Rv0892|M.tuberculosis_H37Rv HQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGEF
MMAR_4641|M.marinum_M YQTVAMPGFPNFFMMLGPHSPVGNYPLTGIAESQADHILRWIQRWRSSEF
MUL_0256|M.ulcerans_Agy99 YQTVAMPGFPNFFMMLDPHSPVGNYPLTGIAESQADHILRWIQRWRSSEF
MAB_0522c|M.abscessus_ATCC_199 YRAVGLAGFPNFFLLIGPNSPIGNNSLISIAETQVKFAMHWIDEIRSGRM
Mvan_3427|M.vanbaalenii_PYR-1 YRAVAVPGFPNMFMLMGPHAPVGNNSLVPVAEDQADYVMWWIDQLRSGRI
MLBr_00065|M.leprae_Br4923 YKGMMLSGLPNMIYTVG----YTNASWTLKADLVSEFFCRLLNYMNANDF
:: :.. ** .. : . : . :
MAV_3915|M.avium_104 QALAPTRAAQDRFNDELQRRLGPSVWNSGGCSSWYLDEHGKNTVLWGGYT
TH_4080|M.thermoresistible__bu QALAPTREAQDRYNAELQARLGRSVWNTGGCRSWYLDEHGNNRVLWGGFT
MSMEG_2310|M.smegmatis_MC2_155 AALAPTRRAQDAFNAELQRDLSGTVFNTGGCKSWYLDEHGVNRTLWSGMT
Mflv_4608|M.gilvum_PYR-GCK STLEVREDRQNNYHGEVQQRLGSTTWNSG-CKSWYLTNDGYNGTMYPGFA
Mb0916|M.bovis_AF2122/97 DTMEPKSAATEAYNTVLRAAMPNTVWTTG-CDSWYLNKDGIP-EVWPFAP
Rv0892|M.tuberculosis_H37Rv DTMEPKSAATEAYNTVLRAAMPNTVWTTG-CDSWYLNKDGIP-EVWPFAP
MMAR_4641|M.marinum_M DTVEPTSWATDEFNAKLRAAMPKTVWTTG-CSSWYLNDDGVP-EVWPFAP
MUL_0256|M.ulcerans_Agy99 DTVEPTSWATDEFNAKLRAAMPKTVWTTG-CSSWYLNDDWVP-EVWPFAP
MAB_0522c|M.abscessus_ATCC_199 QSVAPTAHAAETFNTQMRRAMPNTVWSTG-CDSWYLGADGVP-ELWPWPP
Mvan_3427|M.vanbaalenii_PYR-1 VSAAPTEAATKQYNDAMKAAMPRTVWTTG-CRSWYLGKDGLP-ELFPWEA
MLBr_00065|M.leprae_Br4923 DTVAVEYPGSDVEERPFMDFTPGYVLRSL--DALPKQGSRTPWRLNQNYL
: . . . . : : :
MAV_3915|M.avium_104 WEYWRATRAVKPEEYQFYGIGSRAGV------------------------
TH_4080|M.thermoresistible__bu WQYRLATRTLDPAEYRFWG-------------------------------
MSMEG_2310|M.smegmatis_MC2_155 WQYWKALRRLDPSEFEFLDQRVLARS------------------------
Mflv_4608|M.gilvum_PYR-GCK TQFKRALSKVDMGDYVTTPTTARTEHHPTEHAQNGSNVAKVAQGRKAKVA
Mb0916|M.bovis_AF2122/97 AKHRAMLANLHPEEYDLRRYAAVRATSRPQSA------------------
Rv0892|M.tuberculosis_H37Rv AKHRAMLANLHPEEYDLRRYAAVRATSRPQSA------------------
MMAR_4641|M.marinum_M AEHRAMLANPDLDRYHLRRRPEVLAW------------------------
MUL_0256|M.ulcerans_Agy99 AEHRAMLANPDLDQYHLRRRPEVLAW------------------------
MAB_0522c|M.abscessus_ATCC_199 VDYRRTLTSPIRGDFAIT--------------------------------
Mvan_3427|M.vanbaalenii_PYR-1 SRYAELLRSPQVSDFDVRTAAV----------------------------
MLBr_00065|M.leprae_Br4923 RDIRLIRRGKVADEGLLFAKKTTPVTV-----------------------
MAV_3915|M.avium_104 ----------------------------------------
TH_4080|M.thermoresistible__bu ----------------------------------------
MSMEG_2310|M.smegmatis_MC2_155 ----------------------------------------
Mflv_4608|M.gilvum_PYR-GCK QGRKSAGALPTRSDVKADILDVGVGKVPPKRAASRVRKDA
Mb0916|M.bovis_AF2122/97 ----------------------------------------
Rv0892|M.tuberculosis_H37Rv ----------------------------------------
MMAR_4641|M.marinum_M ----------------------------------------
MUL_0256|M.ulcerans_Agy99 ----------------------------------------
MAB_0522c|M.abscessus_ATCC_199 ----------------------------------------
Mvan_3427|M.vanbaalenii_PYR-1 ----------------------------------------
MLBr_00065|M.leprae_Br4923 ----------------------------------------