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VSDTRDPRVIVVGAGMAGIAVGHKLKEAGFNDFTILEKGDDVGGVWYWNRYPGLTCDVPSQAYQYPFAPR TDWPRLFATGSEIQAYHRKVAEDLDVMPHIRCGQEVTAAEFTGSGWRVTTAAGEALECDFLIAATGVLHH PNIPDIPGLDSFQGAVVHTARWDDSVRLEGKRVAAIGTGSTGVQVVSAMQPVVAQVTSFIRTPQWVLWAP MSLRQPKFVAKLLDALPTQRIVRFTALTGTDALVNIVTRPGWGRRLVQQYARACLHLIRDKELRQKLTPD YEPLCKRQVLSGSFHRAVQKPNVEIVTDRINRITPTGIVTVDGTEREFDVIVLATGFQAHNYMRPMNLVG KDGYSIDEAWEKGPKAYRMTAIPGFPNFFTVLGPNSPTGSIWLQHTAERTAEYIISWLHRFARGEINTVE VSSEATDEFNDQAREAMKPTVWATGCNSWYLTEDGSVDLWPFDRKTMEQMLASPEESHYIVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1527 | - | - | 100% (482) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0522c | - | e-114 | 43.20% (493) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_4476c | - | 4e-82 | 36.92% (455) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0916 | - | 1e-128 | 48.85% (479) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4605 | - | 1e-83 | 34.60% (500) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv0892 | - | 1e-128 | 48.85% (479) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 7e-33 | 26.24% (442) | putative monooxygenase |
| M. marinum M | MMAR_4641 | - | 1e-136 | 49.90% (487) | monooxygenase |
| M. avium 104 | MAV_5119 | - | 2e-81 | 35.73% (459) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 4e-83 | 38.89% (468) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_3452 | - | 2e-81 | 33.75% (483) | PUTATIVE lipolytic enzyme |
| M. ulcerans Agy99 | MUL_0256 | - | 1e-132 | 48.87% (487) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_3427 | - | 1e-116 | 43.72% (478) | putative monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0916|M.bovis_AF2122/97 -----------MTGRCPTVAVVGAGMSGMCVAITLLSAG-ITDVCIYEKA
Rv0892|M.tuberculosis_H37Rv -----------MTGRCPTVAVVGAGMSGMCVAITLLSAG-ITDVCIYEKA
MMAR_4641|M.marinum_M -----------MTRRDPSVAIVGAGMAGICMAITLLNSG-ITDVTIYEKA
MUL_0256|M.ulcerans_Agy99 -----------MTRRDPSVAIVGAAMAGICMAITLLNSG-ITDVTIYEKA
Mvan_3427|M.vanbaalenii_PYR-1 -----------MGIR---VAIIGAGMSGLCMAAKLQDAG-IEDFTVFEKA
MAB_1527|M.abscessus_ATCC_1997 ----------MSDTRDPRVIVVGAGMAGIAVGHKLKEAG-FNDFTILEKG
MAV_5119|M.avium_104 --------MPADPMSELSIGIIGAGPGGLALGILLSQAG-FDDFTIFDRE
TH_3452|M.thermoresistible__bu --------MARN----LSVGIIGAGPGGIALGIFLRRAG-FTDFTIFDRE
Mflv_4605|M.gilvum_PYR-GCK MKPVKREPTQDNPPGNPSIVIIGAGFAGITLALRLKRAG-FDRVLIVEKG
MSMEG_0816|M.smegmatis_MC2_155 -----------MRPVVHDAVIVGAGFAGLGAAIQLKKMS-FDDFVILERE
MLBr_00065|M.leprae_Br4923 -------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKR
::**. .*: . * : ::
Mb0916|M.bovis_AF2122/97 DDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGEIQDYLRG
Rv0892|M.tuberculosis_H37Rv DDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGEIQDYLRG
MMAR_4641|M.marinum_M DEVGGTWRENTYPGLVCDVPSRLYQYSFAKNPDWSNLFSPGGEIQSYFCG
MUL_0256|M.ulcerans_Agy99 DEVGGTWRENTYPGLVCDVPSRLYHYSFAKNPDWSNLFSPGGEIQSYFCG
Mvan_3427|M.vanbaalenii_PYR-1 DEVGGTWRDNTYPGLACDVPSRYYAYSFRPNPEWSHMMPPGPEVFRYFRQ
MAB_1527|M.abscessus_ATCC_1997 DDVGGVWYWNRYPGLTCDVPSQAYQYPFAPRTDWPRLFATGSEIQAYHRK
MAV_5119|M.avium_104 DGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQPEILDYFQR
TH_3452|M.thermoresistible__bu DGVGGTWRINTYPGLACDVKSHLYSYSFELNSEWTRLWPAQPEILRYFER
Mflv_4605|M.gilvum_PYR-GCK DGVGGVWRENTYPGAACDVPSQLYSISSAPNPRWGRRYAEQGDILAYLRR
MSMEG_0816|M.smegmatis_MC2_155 DDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGREIKRYADD
MLBr_00065|M.leprae_Br4923 AGMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTKCQAIAD-GKPILEYIKS
:**.* *** * . : *
Mb0916|M.bovis_AF2122/97 IAERYGLRHRIRFGATVVSARFDDGR--WVLRTD---SGTESTVDFLISA
Rv0892|M.tuberculosis_H37Rv IAERYGLRHRIRFGATVVSARFDDGR--WVLRTD---SGTESTVDFLISA
MMAR_4641|M.marinum_M IADRYRLRDRIRFGTEIVSARFEDDH--WSVVTD---SGEETAVDFLIVA
MUL_0256|M.ulcerans_Agy99 IADRYRLRDRIRFGTEIVSARFEDDH--WSVVTD---SGEETAVDFLIVA
Mvan_3427|M.vanbaalenii_PYR-1 FATERGIRRHIRFGADVTAARFRDGK--WWLTSP---AGDE-EFDVLVTA
MAB_1527|M.abscessus_ATCC_1997 VAEDLDVMPHIRCGQEVTAAEFTGSG--WRVTTA---AGEALECDFLIAA
MAV_5119|M.avium_104 CADKYGLGPHLRLGTEIRSAHWDADTQRWRLTTA---SGHRHHFDVVVSA
TH_3452|M.thermoresistible__bu CAQRHRLGPHLRLNTEITSARWNPTSRQWMLTTG---AGEQHNFDVVVSA
Mflv_4605|M.gilvum_PYR-GCK VADESGLLSLLRTKTEIAKAAFDERTNTWRLTTT---TSQELECDVVISA
MSMEG_0816|M.smegmatis_MC2_155 VADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLT---DGEQLQARFLITA
MLBr_00065|M.leprae_Br4923 TAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLFLC
* : :* : * : * : .:. .
Mb0916|M.bovis_AF2122/97 TGVLHHPR--IPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGSTG
Rv0892|M.tuberculosis_H37Rv TGVLHHPR--IPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGSTG
MMAR_4641|M.marinum_M TGLLHHPR--VPAIAGLDDFGGSAFHSARWDHRVAVQGQRVAVIGSGSTG
MUL_0256|M.ulcerans_Agy99 TGLLHHPR--VPAIAGLDDFGGSAFHSARWDQRVAVQGRRVAVIGSGSTG
Mvan_3427|M.vanbaalenii_PYR-1 TGFLRVPR--YPDILGLDTFTGPMFHSSRWDHSVSLSDKRIGLIGTGSTG
MAB_1527|M.abscessus_ATCC_1997 TGVLHHPN--IPDIPGLDSFQGAVVHTARWDDSVRLEGKRVAAIGTGSTG
MAV_5119|M.avium_104 VGLFTRPL--LPELVEEEPFTGTVMHSARWDHSIPLHGKRIAVLGTGSTA
TH_3452|M.thermoresistible__bu VGMFTRPV--MPDLVEEEPFTGTLMHSARWDHGIDLHGKRIAVLGTGSTA
Mflv_4605|M.gilvum_PYR-GCK VGQLSRPS--VPDIPGISGFAGPSFHSANWDHDLNLSGKRLAVVGTGASS
MSMEG_0816|M.smegmatis_MC2_155 TGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAVVGTGATA
MLBr_00065|M.leprae_Br4923 SGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVIGSGATA
* * : * * .*. * . :. :*:*::.
Mb0916|M.bovis_AF2122/97 VQLVCGLAG-VAGKVTMFQRTAQWVLPWPN-PRYSKLARVFHRAFPCLGS
Rv0892|M.tuberculosis_H37Rv VQLVCGLAG-VAGKVTMFQRTAQWVLPWPN-PRYSKLARVFHRAFPCLGS
MMAR_4641|M.marinum_M VQLVSALAG-VAAKVTMFQRTPQWILPWPN-RQYSKVSRACYRGAPWLES
MUL_0256|M.ulcerans_Agy99 VQLVSALAG-VAAKVTMFQRTRQWILLWPN-RQYSKVSRACYRGAPWLES
Mvan_3427|M.vanbaalenii_PYR-1 VQITSALGG-NVRHLKVFQRTPQWICPWPN-LRVSEHTKAAMRRWTWLNS
MAB_1527|M.abscessus_ATCC_1997 VQVVSAMQP-VVAQVTSFIRTPQWVLWAPMSLRQPKFVAKLLDALPTQRI
MAV_5119|M.avium_104 SQLIPELAK-VAERVYSVQRSPTWILPKPD-RPYTRWERWAFAHLPLAKK
TH_3452|M.thermoresistible__bu SQLIPELAK-IADRVYSVQRSPTWILPKPD-RPYSDRERWVFRHVPFAKR
Mflv_4605|M.gilvum_PYR-GCK VQFVPVVAA-GAEHLDVFQRSAPWVLPKFD-RQYGGRHHQLLRKLPILRL
MSMEG_0816|M.smegmatis_MC2_155 VQLIPELAE-RVAELTVYQRTPIWVVPKVD-VRFPPAVRALFARVPLTQR
MLBr_00065|M.leprae_Br4923 VTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPDKYAYTA
. : . .: *: ::
Mb0916|M.bovis_AF2122/97 LAYKAYS-LSFETFAVALSNPGLHRKLVGAVCRAS---LRR-VRDPRLRR
Rv0892|M.tuberculosis_H37Rv LAYKAYS-LSFETFAVALSNPGLHRKLVGAVCRAS---LRR-VRDPRLRR
MMAR_4641|M.marinum_M LAYKIWG-RAFEQFTAALTRPGWHRRVTGMTCRAS---LRL-VRDPHLRQ
MUL_0256|M.ulcerans_Agy99 LAYKIWG-RAFEQFTAALTRPGWHRRVTGMTCRAS---LRL-VRDPHLRQ
Mvan_3427|M.vanbaalenii_PYR-1 FGYWFWGGFVRSIFGVAPVRPGWQRWLYQTQCHWN---LRLSVRDKELKK
MAB_1527|M.abscessus_ATCC_1997 VRFTALT--GTDALVNIVTRPGWGRRLVQQYARAC---LHL-IRDKELRQ
MAV_5119|M.avium_104 LYRTRLWLRSESNISVIEHGSEKTGQFTNIALGL----LEASVPDEELRR
TH_3452|M.thermoresistible__bu IYRTRLWLRSEANISVIEDGSEKTEEFKAIALKM----LEATVPDEEMRR
Mflv_4605|M.gilvum_PYR-GCK SERLMIWTIFEFLALALVDAKPVARVLGVIALRH----LGRQVSDARLRS
MSMEG_0816|M.smegmatis_MC2_155 VVRAITDAIYAFMVDTAVLKHRYFRRLNIAAADLGRLHLAASIRDPDLRS
MLBr_00065|M.leprae_Br4923 VRWKNILRQSALYGACQKWPQRMRNILLGHVARRLP-------KGYDVQK
. . ::
Mb0916|M.bovis_AF2122/97 ALTPDYEPMCKRLVMS--GGFYRAIQRDDVELVTAGIDHVEHRGIVTDDG
Rv0892|M.tuberculosis_H37Rv ALTPDYEPMCKRLVMS--GGFYRAIQRDDVELVTAGIDHVEHRGIVTDDG
MMAR_4641|M.marinum_M ALTPDYQPMCKRLVMS--SGFYRAIQRDDVELVTTGIDRIENAGIVTDDG
MUL_0256|M.ulcerans_Agy99 ALTPDYQPMCKRLVMS--SGFYRAIQRDDVELVTTGIDRIENAGIVTDDG
Mvan_3427|M.vanbaalenii_PYR-1 KLTPPDQPMCKRMIFA--GHYYRTVQRPDVEIVTDPIVEVQPRGVVTADG
MAB_1527|M.abscessus_ATCC_1997 KLTPDYEPLCKRQVLS--GSFHRAVQKPNVEIVTDRINRITPTGIVTVDG
MAV_5119|M.avium_104 KLTPDHPMGCKRLVFS--SDYLPALTRPNVEVLTSPARSLRRRSLVTEDG
TH_3452|M.thermoresistible__bu RLTPDHPLGCKRLVFS--SDYLAALMRPNVEVVSSPARALRGDTLITEDG
Mflv_4605|M.gilvum_PYR-GCK HLTPDYAPGCKRILFS--SDYYPALARPNVLLVTDDIQAVEPGGIRTVNG
MSMEG_0816|M.smegmatis_MC2_155 KLTPDYDFGCKRPTFS--NSYYRTFTKPHVHLQADGIDHVEPDGIVNADG
MLBr_00065|M.leprae_Br4923 HFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDRFTSTGIRLKSG
: * :* : . :. : * : : . : .*
Mb0916|M.bovis_AF2122/97 VLHEVDVIVLATGFDSHAF-FRPMQLTGRDGIRIDDVWQDG-PHAHQTVA
Rv0892|M.tuberculosis_H37Rv VLHEVDVIVLATGFDSHAF-FRPMQLTGRDGIRIDDVWQDG-PHAHQTVA
MMAR_4641|M.marinum_M VLREVDVIVLATGFDSHAF-FRPMKLIGRDGVEIDELWRGG-PYAYQTVA
MUL_0256|M.ulcerans_Agy99 VLREVDVIVLATGFDSHAF-FRPMKLIGRDGVEIDELWRGG-PYAYQTVA
Mvan_3427|M.vanbaalenii_PYR-1 TLHEVDLLALATGFDFHAY-VRPLTITGEHGRTLDDAWADG-PTAYRAVA
MAB_1527|M.abscessus_ATCC_1997 TEREFDVIVLATGFQAHNY-MRPMNLVGKDGYSIDEAWEKG-PKAYRMTA
MAV_5119|M.avium_104 TEREVDLVVCATGYAAADY-LGELDVTGEHGVTLREVWRDG-AYAYLGMA
TH_3452|M.thermoresistible__bu TERRVDVVVCATGYAAADY-LGQIEVVGERQRSLREVWRDG-AYAYLGMT
Mflv_4605|M.gilvum_PYR-GCK DFHAADVIIYGTGFSATEF-LSPMEVYGRSDRKLSDVWADG-AHAYYGLS
MSMEG_0816|M.smegmatis_MC2_155 SKTVIDTLVLATGFDLWEANFPAIEVIGRQGRDLGKWWRETRFQAYQGVS
MLBr_00065|M.leprae_Br4923 NELRADIIVTATGLNLQLF---GGAVATVDGQPVDLAQTMS----YKGMM
* : .** : : :
Mb0916|M.bovis_AF2122/97 IPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGEFDTMEP
Rv0892|M.tuberculosis_H37Rv IPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGEFDTMEP
MMAR_4641|M.marinum_M MPGFPNFFMMLGPHSPVGNYPLTGIAESQADHILRWIQRWRSSEFDTVEP
MUL_0256|M.ulcerans_Agy99 MPGFPNFFMMLDPHSPVGNYPLTGIAESQADHILRWIQRWRSSEFDTVEP
Mvan_3427|M.vanbaalenii_PYR-1 VPGFPNMFMLMGPHAPVGNNSLVPVAEDQADYVMWWIDQLRSGRIVSAAP
MAB_1527|M.abscessus_ATCC_1997 IPGFPNFFTVLGPNSPTGSIWLQHTAERTAEYIISWLHRFARGEINTVEV
MAV_5119|M.avium_104 VPGFPNFFMLYGPNTNVGSNSVIFVLEAQARYIVRALKYLRRHRRRYIAV
TH_3452|M.thermoresistible__bu VPGFPNFFMLYGPNTNVGSNSVLFILEAQARYVVKALKRLRRRDTSYIAV
Mflv_4605|M.gilvum_PYR-GCK VPEFPNFLMMYGPNTNVGSGSIVYMLESQARHIVRLMKVLRAHPGSVIEV
MSMEG_0816|M.smegmatis_MC2_155 MPYFPNYLSLAGPYAFLGLN-FFNTMEYQMRLMERLLGEVARRDARTFEV
MLBr_00065|M.leprae_Br4923 LSGLPNMIYTVG----YTNASWTLKADLVSEFFCRLLNYMNANDFDTVAV
:. :** : . : . :
Mb0916|M.bovis_AF2122/97 KSAATEAYNTVLRAAMPNTVWTTG-------CDSWYLNKDG-IPEVWPFA
Rv0892|M.tuberculosis_H37Rv KSAATEAYNTVLRAAMPNTVWTTG-------CDSWYLNKDG-IPEVWPFA
MMAR_4641|M.marinum_M TSWATDEFNAKLRAAMPKTVWTTG-------CSSWYLNDDG-VPEVWPFA
MUL_0256|M.ulcerans_Agy99 TSWATDEFNAKLRAAMPKTVWTTG-------CSSWYLNDDW-VPEVWPFA
Mvan_3427|M.vanbaalenii_PYR-1 TEAATKQYNDAMKAAMPRTVWTTG-------CRSWYLGKDG-LPELFPWE
MAB_1527|M.abscessus_ATCC_1997 SSEATDEFNDQAREAMKPTVWATG-------CNSWYLTEDG-SVDLWPFD
MAV_5119|M.avium_104 RPAALADFVAKIDRWMVGTVWTT-------QCSNYFRAPNGRVVTQWPRS
TH_3452|M.thermoresistible__bu RPDTAAAFLAKVDQWMQGKVWST-------QCNNYFRAPNGRVVTQWPRS
Mflv_4605|M.gilvum_PYR-GCK RADVEKRFNDRLSRRLDRSVWT--------MCTSWYRSARGSISTNWPSP
MSMEG_0816|M.smegmatis_MC2_155 TEEANRRYLDRMTDALGDSLFTLGNCA---SARSYYFNPSGEATLLRPMT
MLBr_00065|M.leprae_Br4923 EYPGSDVEERPFMDFTPGYVLRSLDALPKQGSRTPWRLNQNYLRDIRLIR
: . . :
Mb0916|M.bovis_AF2122/97 PAKHRAMLANLHPEEYDLRRYAAVRATSRPQSA-----------------
Rv0892|M.tuberculosis_H37Rv PAKHRAMLANLHPEEYDLRRYAAVRATSRPQSA-----------------
MMAR_4641|M.marinum_M PAEHRAMLANPDLDRYHLRRRPEVLAW-----------------------
MUL_0256|M.ulcerans_Agy99 PAEHRAMLANPDLDQYHLRRRPEVLAW-----------------------
Mvan_3427|M.vanbaalenii_PYR-1 ASRYAELLRSPQVSDFDVRTAAV---------------------------
MAB_1527|M.abscessus_ATCC_1997 RKTMEQMLASPEESHYIVR-------------------------------
MAV_5119|M.avium_104 ARAFWSMTRRFRPADYRFQAP-----------------AVRVPAPASEAD
TH_3452|M.thermoresistible__bu ARAFWAMTRRFRSADYLFEPAP---------------DMSEVSADARPVA
Mflv_4605|M.gilvum_PYR-GCK TFLYRLRARRPKRRAYVLSRPAPANSSRRGTPEPANTHLADMPYAPSGAD
MSMEG_0816|M.smegmatis_MC2_155 TRRAVAEASRFPLSDYTFA-------------------------------
MLBr_00065|M.leprae_Br4923 RGKVADEGLLFAKKTTPVTV------------------------------
.
Mb0916|M.bovis_AF2122/97 ---
Rv0892|M.tuberculosis_H37Rv ---
MMAR_4641|M.marinum_M ---
MUL_0256|M.ulcerans_Agy99 ---
Mvan_3427|M.vanbaalenii_PYR-1 ---
MAB_1527|M.abscessus_ATCC_1997 ---
MAV_5119|M.avium_104 AR-
TH_3452|M.thermoresistible__bu SR-
Mflv_4605|M.gilvum_PYR-GCK SVD
MSMEG_0816|M.smegmatis_MC2_155 ---
MLBr_00065|M.leprae_Br4923 ---