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TRRDPSVAIVGAGMAGICMAITLLNSGITDVTIYEKADEVGGTWRENTYPGLVCDVPSRLYQYSFAKNPD WSNLFSPGGEIQSYFCGIADRYRLRDRIRFGTEIVSARFEDDHWSVVTDSGEETAVDFLIVATGLLHHPR VPAIAGLDDFGGSAFHSARWDHRVAVQGQRVAVIGSGSTGVQLVSALAGVAAKVTMFQRTPQWILPWPNR QYSKVSRACYRGAPWLESLAYKIWGRAFEQFTAALTRPGWHRRVTGMTCRASLRLVRDPHLRQALTPDYQ PMCKRLVMSSGFYRAIQRDDVELVTTGIDRIENAGIVTDDGVLREVDVIVLATGFDSHAFFRPMKLIGRD GVEIDELWRGGPYAYQTVAMPGFPNFFMMLGPHSPVGNYPLTGIAESQADHILRWIQRWRSSEFDTVEPT SWATDEFNAKLRAAMPKTVWTTGCSSWYLNDDGVPEVWPFAPAEHRAMLANPDLDRYHLRRRPEVLAW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4641 | - | - | 100% (489) | monooxygenase |
| M. marinum M | MMAR_0403 | - | 6e-95 | 41.52% (460) | monooxygenase |
| M. marinum M | MMAR_3139 | - | 1e-90 | 36.51% (482) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0916 | - | 0.0 | 72.13% (488) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4608 | - | 4e-93 | 37.37% (479) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv0892 | - | 0.0 | 72.13% (488) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 9e-31 | 27.76% (425) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_0522c | - | 1e-144 | 49.79% (476) | monooxygenase |
| M. avium 104 | MAV_5119 | - | 1e-92 | 39.50% (481) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_2567 | - | 6e-91 | 37.88% (462) | monooxygenase |
| M. thermoresistible (build 8) | TH_4080 | - | 4e-90 | 39.91% (451) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0256 | - | 0.0 | 98.16% (489) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_3427 | - | 1e-144 | 49.79% (476) | putative monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4641|M.marinum_M -----------MTR-----------RDPSVAIVGAGMAGICMAITLLN-S
MUL_0256|M.ulcerans_Agy99 -----------MTR-----------RDPSVAIVGAAMAGICMAITLLN-S
Mb0916|M.bovis_AF2122/97 -----------MTG-----------RCPTVAVVGAGMSGMCVAITLLS-A
Rv0892|M.tuberculosis_H37Rv -----------MTG-----------RCPTVAVVGAGMSGMCVAITLLS-A
MAB_0522c|M.abscessus_ATCC_199 -----------MSNGAYTAVEKTRSRDIRVVVIGAGMSGLCMASTLRH-R
Mvan_3427|M.vanbaalenii_PYR-1 -----------MG--------------IRVAIIGAGMSGLCMAAKLQD-A
Mflv_4608|M.gilvum_PYR-GCK -----------MSDT------------TTVLIVGAGFAGLGTAIRLLQ-Q
TH_4080|M.thermoresistible__bu MTVTEPSADITPANTP-----TQPPVRTRALIVGTGFSGLGMAIALQR-R
MAV_5119|M.avium_104 -----------MPADPMSE--------LSIGIIGAGPGGLALGILLSQ-A
MSMEG_2567|M.smegmatis_MC2_155 -----------MSADRMS---------MSIGIIGAGPGGLALGIFLKK-A
MLBr_00065|M.leprae_Br4923 --------MVVMAET----------EYLDVVIVGAGISGVSAAWHLQDRC
::*:. .*: . *
MMAR_4641|M.marinum_M GITDVTIYEKADEVGGTWRENTYPGLVCDVPSRLYQYSFAKNPDWSNLFS
MUL_0256|M.ulcerans_Agy99 GITDVTIYEKADEVGGTWRENTYPGLVCDVPSRLYHYSFAKNPDWSNLFS
Mb0916|M.bovis_AF2122/97 GITDVCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFS
Rv0892|M.tuberculosis_H37Rv GITDVCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFS
MAB_0522c|M.abscessus_ATCC_199 GITNFTVYEKADEVGGTWRDNTYPGLQCDVPSRYYSYSFAPNPRWSKGFS
Mvan_3427|M.vanbaalenii_PYR-1 GIEDFTVFEKADEVGGTWRDNTYPGLACDVPSRYYAYSFRPNPEWSHMMP
Mflv_4608|M.gilvum_PYR-GCK GIDDFVVLERADEVGGTWRDNTYPGAACDIPSLLYSYGFEQNPDWSRAYS
TH_4080|M.thermoresistible__bu GID-FLMLEKADDIGGTWRDNTYPGCACDIPSHLYSFSFEPKADWRHLFS
MAV_5119|M.avium_104 GFDDFTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWS
MSMEG_2567|M.smegmatis_MC2_155 GFRDFTIFDREDGVGGTWRINTYPGLACDVKSHLYSYSFDLNADWTRLWS
MLBr_00065|M.leprae_Br4923 PNKSYVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTKCQAIAD
: :: :**** *** .* : * .
MMAR_4641|M.marinum_M PGGEIQSYFCGIADRYRLRDRIRFGTEIVSARFED----DHWSVVTD---
MUL_0256|M.ulcerans_Agy99 PGGEIQSYFCGIADRYRLRDRIRFGTEIVSARFED----DHWSVVTD---
Mb0916|M.bovis_AF2122/97 RGGEIQDYLRGIAERYGLRHRIRFGATVVSARFDD----GRWVLRTD---
Rv0892|M.tuberculosis_H37Rv RGGEIQDYLRGIAERYGLRHRIRFGATVVSARFDD----GRWVLRTD---
MAB_0522c|M.abscessus_ATCC_199 PGSEIHQYFVRFTDQQDLRRNIRFGTAVTRAEWVDEPGQSHWELELS---
Mvan_3427|M.vanbaalenii_PYR-1 PGPEVFRYFRQFATERGIRRHIRFGADVTAARFRD----GKWWLTSP---
Mflv_4608|M.gilvum_PYR-GCK GSAEILGYIKTMVDKYSLSRFIRFGVNVTGLEFDEE--SALWTAQTA---
TH_4080|M.thermoresistible__bu YQDEIQEYLQGVTAKYGLRRYIHFDSLVDRAHWDDT--EHRWHVFTA---
MAV_5119|M.avium_104 GQPEILDYFQRCADKYGLGPHLRLGTEIRSAHWDADTQ--RWRLTTA---
MSMEG_2567|M.smegmatis_MC2_155 SQPEILAYFERCAQRHQLESHLVLGTEITSARWDTDG----WVLTTS---
MLBr_00065|M.leprae_Br4923 GKP-ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIEN--RWTVQVENNG
: *: . : : :. : : *
MMAR_4641|M.marinum_M SGEETAVDFLIVATGLLHHPR--VPAIAGLDDFGGSAFHSARWDHRVAVQ
MUL_0256|M.ulcerans_Agy99 SGEETAVDFLIVATGLLHHPR--VPAIAGLDDFGGSAFHSARWDQRVAVQ
Mb0916|M.bovis_AF2122/97 SGTESTVDFLISATGVLHHPR--IPPIAGLDDFRGTVFHSARWDHTVPLL
Rv0892|M.tuberculosis_H37Rv SGTESTVDFLISATGVLHHPR--IPPIAGLDDFRGTVFHSARWDHTVPLL
MAB_0522c|M.abscessus_ATCC_199 DGGRDIADVVVGATGVLHLPR--LPEIEGLQSFAGPCFHSARWDHSVPYI
Mvan_3427|M.vanbaalenii_PYR-1 AGD-EEFDVLVTATGFLRVPR--YPDILGLDTFTGPMFHSSRWDHSVSLS
Mflv_4608|M.gilvum_PYR-GCK DGSQFTARTAVMASGPLANAS--LPDIRGLDTFDGHKIHSARWDHDYDMS
TH_4080|M.thermoresistible__bu DGREYIAQFLISCAGALHIPS--IPDFPGRDQFAGPAFHSAQWDHSVDLT
MAV_5119|M.avium_104 SGHRHHFDVVVSAVGLFTRPL--LPELVEEEPFTGTVMHSARWDHSIPLH
MSMEG_2567|M.smegmatis_MC2_155 GGDEQRFDFVVSAVGLFTQPL--LPDLVEEEPFTGTVLHTARWDHSIPLA
MLBr_00065|M.leprae_Br4923 TPRMISCSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYA
. . * * : : * * :*. :* .
MMAR_4641|M.marinum_M GQRVAVIGSGSTGVQLVSALAGV-AAKVTMFQRTPQWILPWPNRQYSKVS
MUL_0256|M.ulcerans_Agy99 GRRVAVIGSGSTGVQLVSALAGV-AAKVTMFQRTRQWILLWPNRQYSKVS
Mb0916|M.bovis_AF2122/97 GRRIAVIGTGSTGVQLVCGLAGV-AGKVTMFQRTAQWVLPWPNPRYSKLA
Rv0892|M.tuberculosis_H37Rv GRRIAVIGTGSTGVQLVCGLAGV-AGKVTMFQRTAQWVLPWPNPRYSKLA
MAB_0522c|M.abscessus_ATCC_199 GKRVGLIGTGSSGVQIIGALAEQ-VQHLSVFQRSAQWVAPVPNFTYSALS
Mvan_3427|M.vanbaalenii_PYR-1 DKRIGLIGTGSTGVQITSALGGN-VRHLKVFQRTPQWICPWPNLRVSEHT
Mflv_4608|M.gilvum_PYR-GCK DKRVAVIGTGASAVQIIPELVKT-ARSVKVFQRTPGWVLPRPDFSHPQWV
TH_4080|M.thermoresistible__bu GKRVAVIGTGASAIQIVPEIIDR-VAQLQLYQRTPAWVVPRTNDELPAWL
MAV_5119|M.avium_104 GKRIAVLGTGSTASQLIPELAKV-AERVYSVQRSPTWILPKPDRPYTRWE
MSMEG_2567|M.smegmatis_MC2_155 GKKIAVLGTGSTAAQLVPELAKV-ADTVYSVQRSPTWILPKPDRPYTDRE
MLBr_00065|M.leprae_Br4923 AKNIVVIGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAAR
:.: ::*:*::. : : . : **: :: .
MMAR_4641|M.marinum_M RACYRGAPWLESLAYKIWGRAFEQ-FTAALTRPGWHRRVTGMTCRASLRL
MUL_0256|M.ulcerans_Agy99 RACYRGAPWLESLAYKIWGRAFEQ-FTAALTRPGWHRRVTGMTCRASLRL
Mb0916|M.bovis_AF2122/97 RVFHRAFPCLGSLAYKAYSLSFET-FAVALSNPGLHRKLVGAVCRASLRR
Rv0892|M.tuberculosis_H37Rv RVFHRAFPCLGSLAYKAYSLSFET-FAVALSNPGLHRKLVGAVCRASLRR
MAB_0522c|M.abscessus_ATCC_199 KSIWSRIPVLNRISYLLWRFYFERGVGGSVVIPGARRKLIQGFVRASHRL
Mvan_3427|M.vanbaalenii_PYR-1 KAAMRRWTWLNSFGYWFWGGFVRSIFGVAPVRPGWQRWLYQTQCHWNLRL
Mflv_4608|M.gilvum_PYR-GCK RTAFRRLPRVQNVGRQAWFWGHEL-MAVGMVWDTPVTTGIQLLAKANLRR
TH_4080|M.thermoresistible__bu RRALENIPGLRLALRGGIYALQEA-LAVGMTKYPGMLRIGHLLGKWNINR
MAV_5119|M.avium_104 RWAFAHLPLAKKLYRTRLWLRSES-NISVIEHGSEKTGQFTNIALGLLEA
MSMEG_2567|M.smegmatis_MC2_155 RWVFAHVPLAKKIYRTRLWLRSES-NISVIEHGSDKTQEFRSIALNMLRS
MLBr_00065|M.leprae_Br4923 LNRWLPDKYAYTAVRWKNILRQSALYGACQKWP---QRMRNILLGHVARR
.
MMAR_4641|M.marinum_M -VRDPHLRQALTPDYQPMCKRLVMS--SGFYRAIQRDDVELVTTGIDRIE
MUL_0256|M.ulcerans_Agy99 -VRDPHLRQALTPDYQPMCKRLVMS--SGFYRAIQRDDVELVTTGIDRIE
Mb0916|M.bovis_AF2122/97 -VRDPRLRRALTPDYEPMCKRLVMS--GGFYRAIQRDDVELVTAGIDHVE
Rv0892|M.tuberculosis_H37Rv -VRDPRLRRALTPDYEPMCKRLVMS--GGFYRAIQRDDVELVTAGIDHVE
MAB_0522c|M.abscessus_ATCC_199 LIRDATLREKLHPDYEPLCRRLVMS--VPFFKAVQRPNVSVLTGGIDRVV
Mvan_3427|M.vanbaalenii_PYR-1 SVRDKELKKKLTPPDQPMCKRMIFA--GHYYRTVQRPDVEIVTDPIVEVQ
Mflv_4608|M.gilvum_PYR-GCK QVSDTWLRRQLTPNFRAGCKRMLMS--SDYYPALQRDNCKLVSWPIATLS
TH_4080|M.thermoresistible__bu SVKDPQLRAKLTPDYRLGCKRILNS--STYYPAVADPRTEVITESIDRIT
MAV_5119|M.avium_104 SVPDEELRRKLTPDHPMGCKRLVFS--SDYLPALTRPNVEVLTSPARSLR
MSMEG_2567|M.smegmatis_MC2_155 TVTDDELRERLTPDHPLGCKRLVFS--SDFIPTLTRPNVEVVSSPARALR
MLBr_00065|M.leprae_Br4923 LPKGYDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDRFT
. :: : * :*: :: .::: .
MMAR_4641|M.marinum_M NAGIVTDDGVLREVDVIVLATGFDSHAFFRPMKLIGRDGVEIDELWR-GG
MUL_0256|M.ulcerans_Agy99 NAGIVTDDGVLREVDVIVLATGFDSHAFFRPMKLIGRDGVEIDELWR-GG
Mb0916|M.bovis_AF2122/97 HRGIVTDDGVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQ-DG
Rv0892|M.tuberculosis_H37Rv HRGIVTDDGVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQ-DG
MAB_0522c|M.abscessus_ATCC_199 PQGVITNDGVLHELDILVCATGFDAHSYLRPMEVLGRDGIKLSDAWS-DG
Mvan_3427|M.vanbaalenii_PYR-1 PRGVVTADGTLHEVDLLALATGFDFHAYVRPLTITGEHGRTLDDAWA-DG
Mflv_4608|M.gilvum_PYR-GCK PNGIRTADGIEHELDCIVFATGFDVCKAGTPFPIRGAHGRELSDEWS-QG
TH_4080|M.thermoresistible__bu TDGIVTSDGTERAVDVIVYATGFHVSDSYKYVQIKGLNGEDIVDRFNREG
MAV_5119|M.avium_104 RRSLVTEDGTEREVDLVVCATGYAAADYLGELDVTGEHGVTLREVWR-DG
MSMEG_2567|M.smegmatis_MC2_155 SRSLVTEDGRELDVDIVACATGYAAADYLGQIEVTGEGGIRLHDVWR-DG
MLBr_00065|M.leprae_Br4923 STGIRLKSGNELRADIIVTATGLNLQLFGGAVATVDGQPVDLAQTMS---
.: .* * :. *** . . : :
MMAR_4641|M.marinum_M PYAYQTVAMPGFPNFFMMLGPHSPVGNYPLTGIAESQADHILRWIQRWRS
MUL_0256|M.ulcerans_Agy99 PYAYQTVAMPGFPNFFMMLDPHSPVGNYPLTGIAESQADHILRWIQRWRS
Mb0916|M.bovis_AF2122/97 PHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRH
Rv0892|M.tuberculosis_H37Rv PHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRH
MAB_0522c|M.abscessus_ATCC_199 PRAYRAVGLAGFPNFFLLIGPNSPIGNNSLISIAETQVKFAMHWIDEIRS
Mvan_3427|M.vanbaalenii_PYR-1 PTAYRAVAVPGFPNMFMLMGPHAPVGNNSLVPVAEDQADYVMWWIDQLRS
Mflv_4608|M.gilvum_PYR-GCK AYAYRSVTVAGYPNLFFTFGPNSGPGHNSALVYMEAEINYIVKAIGAIIA
TH_4080|M.thermoresistible__bu PMAHRGTAVADLPNAYLLLGPNTGLGHNSMVYMIESQINYVIEAIKAVDK
MAV_5119|M.avium_104 AYAYLGMAVPGFPNFFMLYGPNTNVGSNSVIFVLEAQARYIVRALKYLRR
MSMEG_2567|M.smegmatis_MC2_155 AYAYLGMTVPGFPNFFMLYGPNTNVGSNSVIFVLEAQARYVVRALKHLRR
MLBr_00065|M.leprae_Br4923 ---YKGMMLSGLPNMIYTVG----YTNASWTLKADLVSEFFCRLLNYMNA
: :.. ** . . : . :
MMAR_4641|M.marinum_M SEFDTVEPTSWATDEFNAKLRAAMPKTVWTTG-CSSWYLNDDGVP-EVWP
MUL_0256|M.ulcerans_Agy99 SEFDTVEPTSWATDEFNAKLRAAMPKTVWTTG-CSSWYLNDDWVP-EVWP
Mb0916|M.bovis_AF2122/97 GEFDTMEPKSAATEAYNTVLRAAMPNTVWTTG-CDSWYLNKDGIP-EVWP
Rv0892|M.tuberculosis_H37Rv GEFDTMEPKSAATEAYNTVLRAAMPNTVWTTG-CDSWYLNKDGIP-EVWP
MAB_0522c|M.abscessus_ATCC_199 GRMQSVAPTAHAAETFNTQMRRAMPNTVWSTG-CDSWYLGADGVP-ELWP
Mvan_3427|M.vanbaalenii_PYR-1 GRIVSAAPTEAATKQYNDAMKAAMPRTVWTTG-CRSWYLGKDGLP-ELFP
Mflv_4608|M.gilvum_PYR-GCK NDLSTLEVREDRQNNYHGEVQQRLGSTTWNSG-CKSWYLTNDGYNGTMYP
TH_4080|M.thermoresistible__bu AGAQALAPTREAQDRYNAELQARLGRSVWNTGGCRSWYLDEHGNNRVLWG
MAV_5119|M.avium_104 HRRRYIAVRPAALADFVAKIDRWMVGTVWTTQ-CSNYFRAPNGRVVTQWP
MSMEG_2567|M.smegmatis_MC2_155 RRKSYVAVKPEVMAQFIADIDRWMQGTVWLTR-CSSYFRAPNGRVVTQWP
MLBr_00065|M.leprae_Br4923 NDFDTVAVEYPGSDVEERPFMDFTPGYVLRSL--DALPKQGSRTPWRLNQ
. . :
MMAR_4641|M.marinum_M FAPAEHRAMLANPDLDRYHLRRRPEVLAW---------------------
MUL_0256|M.ulcerans_Agy99 FAPAEHRAMLANPDLDQYHLRRRPEVLAW---------------------
Mb0916|M.bovis_AF2122/97 FAPAKHRAMLANLHPEEYDLRRYAAVRATSRPQSA---------------
Rv0892|M.tuberculosis_H37Rv FAPAKHRAMLANLHPEEYDLRRYAAVRATSRPQSA---------------
MAB_0522c|M.abscessus_ATCC_199 WPPVDYRRTLTSPIRGDFAIT-----------------------------
Mvan_3427|M.vanbaalenii_PYR-1 WEASRYAELLRSPQVSDFDVRTAAV-------------------------
Mflv_4608|M.gilvum_PYR-GCK GFATQFKRALSKVDMGDYVTTPTTARTEHHPTEHAQNGSNVAKVAQGRKA
TH_4080|M.thermoresistible__bu GFTWQYRLATRTLDPAEYRFWG----------------------------
MAV_5119|M.avium_104 RSARAFWSMTRRFRPADYRFQAPAVRVPAPASEADAR-------------
MSMEG_2567|M.smegmatis_MC2_155 RSARALWAMTRRFRAADYLFSAP-VDGQAQVVEVAAHETVG---------
MLBr_00065|M.leprae_Br4923 NYLRDIRLIRRGKVADEGLLFAKKTTPVTV--------------------
MMAR_4641|M.marinum_M -------------------------------------------
MUL_0256|M.ulcerans_Agy99 -------------------------------------------
Mb0916|M.bovis_AF2122/97 -------------------------------------------
Rv0892|M.tuberculosis_H37Rv -------------------------------------------
MAB_0522c|M.abscessus_ATCC_199 -------------------------------------------
Mvan_3427|M.vanbaalenii_PYR-1 -------------------------------------------
Mflv_4608|M.gilvum_PYR-GCK KVAQGRKSAGALPTRSDVKADILDVGVGKVPPKRAASRVRKDA
TH_4080|M.thermoresistible__bu -------------------------------------------
MAV_5119|M.avium_104 -------------------------------------------
MSMEG_2567|M.smegmatis_MC2_155 -------------------------------------------
MLBr_00065|M.leprae_Br4923 -------------------------------------------