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M. thermoresistible (build 8) TH_3268 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 824703 - 825488
length: 262

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3268--100% (262)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_2552-5e-3535.83% (254) PUTATIVE putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_2623-7e-3433.86% (254) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3560c-1e-11279.92% (254) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1530-1e-11783.14% (255) short chain dehydrogenase
M. tuberculosis H37RvRv3530c-1e-11279.92% (254) short chain dehydrogenase
M. leprae Br4923MLBr_02565fabG7e-1627.24% (257) 3-ketoacyl-(acyl-carrier-protein) reductase
M. abscessus ATCC 19977MAB_4178c-1e-10269.50% (259) short chain dehydrogenase
M. marinum MMMAR_5018-1e-10976.77% (254) short-chain alcohol dehydrogenase
M. avium 104MAV_0630-1e-11079.13% (254) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_5931-1e-11380.00% (255) short chain dehydrogenase
M. ulcerans Agy99MUL_4092-1e-10275.00% (244) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_5228-1e-11481.18% (255) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3560c|M.bovis_AF2122/97           --------------------------------------------------
Rv3530c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5018|M.marinum_M               --------------------------------------------------
MUL_4092|M.ulcerans_Agy99           --------------------------------------------------
MAV_0630|M.avium_104                --------------------------------------------------
Mflv_1530|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5228|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5931|M.smegmatis_MC2_155      --------------------------------------------------
TH_3268|M.thermoresistible__bu      --------------------------------------------------
MAB_4178c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
                                                                                      

Mb3560c|M.bovis_AF2122/97           --------------------------------------------------
Rv3530c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5018|M.marinum_M               --------------------------------------------------
MUL_4092|M.ulcerans_Agy99           --------------------------------------------------
MAV_0630|M.avium_104                --------------------------------------------------
Mflv_1530|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5228|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5931|M.smegmatis_MC2_155      --------------------------------------------------
TH_3268|M.thermoresistible__bu      --------------------------------------------------
MAB_4178c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
                                                                                      

Mb3560c|M.bovis_AF2122/97           --------------------------------------------------
Rv3530c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5018|M.marinum_M               --------------------------------------------------
MUL_4092|M.ulcerans_Agy99           --------------------------------------------------
MAV_0630|M.avium_104                --------------------------------------------------
Mflv_1530|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5228|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5931|M.smegmatis_MC2_155      --------------------------------------------------
TH_3268|M.thermoresistible__bu      --------------------------------------------------
MAB_4178c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
                                                                                      

Mb3560c|M.bovis_AF2122/97           --------------------------------------------------
Rv3530c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5018|M.marinum_M               --------------------------------------------------
MUL_4092|M.ulcerans_Agy99           --------------------------------------------------
MAV_0630|M.avium_104                --------------------------------------------------
Mflv_1530|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5228|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5931|M.smegmatis_MC2_155      --------------------------------------------------
TH_3268|M.thermoresistible__bu      --------------------------------------------------
MAB_4178c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02565|M.leprae_Br4923          ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
                                                                                      

Mb3560c|M.bovis_AF2122/97           ------MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARS--AE
Rv3530c|M.tuberculosis_H37Rv        ------MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARS--AE
MMAR_5018|M.marinum_M               ------MPGLLDGKTLVISGVGPGLGTTLAHRCAAEGADLVLAARS--GD
MUL_4092|M.ulcerans_Agy99           --------------------MGPGLGTTLAHRCAAEGADLVLAARI--GD
MAV_0630|M.avium_104                ---------MLDGKVVVISGVGPGLGTTLAHRCADSGADLVLAART--AE
Mflv_1530|M.gilvum_PYR-GCK          ---MSEALPLLENKVVVISGVGPALGTTLARRCAEAGADLVLAART--VE
Mvan_5228|M.vanbaalenii_PYR-1       -----MAFGLLRDKVVVISGVGPALGTTLARRCAEEGADLVLAART--VE
MSMEG_5931|M.smegmatis_MC2_155      ------MGGLLTDKVVVISGVGPALGTTLARRCAEQGADLVLAART--VE
TH_3268|M.thermoresistible__bu      -----MTMLSLDNKVVVISGVGPALGTTLARRCAAAGADLVLAART--AE
MAB_4178c|M.abscessus_ATCC_199      -----MSLLNFDGKVVVVSGIGPGLGAALAIKFAEAGADVVLAART--QS
MLBr_02565|M.leprae_Br4923          STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE
                                                         . .:*:::*   *  ** :*        .

Mb3560c|M.bovis_AF2122/97           RLDDVAKQIIDTGRRAVAVRTDITDDDDVSNLVQATLAAYG-KADVLINN
Rv3530c|M.tuberculosis_H37Rv        RLDDVAKQIIDTGRRAVAVRTDITDDDDVSNLVQATLAAYG-KADVLINN
MMAR_5018|M.marinum_M               RLDELAKQIIDKGRQAIAVRADITDDDQVSNLVDATLEAYG-KIDVLVNN
MUL_4092|M.ulcerans_Agy99           RLDELAKQIIDKGRQAIAVRADITDDDQVSNLVDATLEAYG-KIDVLVNN
MAV_0630|M.avium_104                RLEKVAKQVNDGGHRALAVRTDITDDDEVAYLVETTMATYG-RADVLINN
Mflv_1530|M.gilvum_PYR-GCK          RLEDVATQITDLGRRAVSVGTDITDEAQVANLVEESLKAYG-KVDVLINN
Mvan_5228|M.vanbaalenii_PYR-1       RLDDVARQITDLGRRAVSVGTDITDEAQVNNLVDESLKAYG-KVDVLINN
MSMEG_5931|M.smegmatis_MC2_155      RLEDVAKQVTDTGRRALSVGTDITDDAQVAHLVDETMKAYG-RVDVVINN
TH_3268|M.thermoresistible__bu      RLEEVAGQITATGRRAVAVPTDITDEAQVANLVAETNKAYG-RVDVLINN
MAB_4178c|M.abscessus_ATCC_199      RLDEVARQIAATGRRALAVATDITDEASAANLVERATEEFG-GIDVLVNN
MLBr_02565|M.leprae_Br4923          ALDETANRVG-----GTTLSLDVTADDAVDKITEHLHDYQGGHADILVNN
                                     *:. * ::      . ::  *:* :  .  :.       *   *:::**

Mb3560c|M.bovis_AF2122/97           AFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTPALAQSHG-AIVN
Rv3530c|M.tuberculosis_H37Rv        AFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTPALAQSHG-AIVN
MMAR_5018|M.marinum_M               AFRVPSMKPLAETTFQHIRDAIELSALGALRVIAGFTRALAETNG-SIVN
MUL_4092|M.ulcerans_Agy99           AFRVPSMKPLAETTFQHIRDAIELSALGALRVIAGFTRALAETNG-SIVN
MAV_0630|M.avium_104                AFRVPSMKPLAGTSFQHIRDAIELSALGALRLIQAFTPALETAHG-SIVN
Mflv_1530|M.gilvum_PYR-GCK          AFRVPSMKPFANTTFEHMRDAIELTVFGALRMVQAFTPALAEANG-AVVN
Mvan_5228|M.vanbaalenii_PYR-1       AFRVPSMKPFADTTFEHMRDAIELTVFGALRMVQAFSPALAEANG-AVVN
MSMEG_5931|M.smegmatis_MC2_155      AFRVPSMKPFANTTFEHMRDAIELTVFGALRLIQGFTPALEESKG-AVVN
TH_3268|M.thermoresistible__bu      AFRVPSMKPLANTGFDHIREAIELTVLGALRLTQALTPALAQANG-SVVN
MAB_4178c|M.abscessus_ATCC_199      AFSIPSMKSLEKTDYQHIRDSVELTVVGTLRLTQRVAAALAQSKG-AVVN
MLBr_02565|M.leprae_Br4923          AG-ITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKGGRVIV
                                    *  :.  * :      :    :*:. ... *:   .      ::*  :: 

Mb3560c|M.bovis_AF2122/97           VNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIW
Rv3530c|M.tuberculosis_H37Rv        VNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIW
MMAR_5018|M.marinum_M               VNSMVLRHSQPKFGAYKMAKSTLLAMSHSLAAELGVKGIRVNSVAPGYIW
MUL_4092|M.ulcerans_Agy99           VNSMVLRHSQPKFGADKTAKSTLLAMSHSLAAELGVKGIWVNSVAPGYIW
MAV_0630|M.avium_104                VNSMVLRHSQAKYGAYKMAKSALLSMSQSLATELGEKGIRVNSVAPGYIW
Mflv_1530|M.gilvum_PYR-GCK          VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGDQGIRVNSVLPGYIW
Mvan_5228|M.vanbaalenii_PYR-1       VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGEQGIRVNSVLPGYIW
MSMEG_5931|M.smegmatis_MC2_155      VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGEKGIRVNSVLPGYIW
TH_3268|M.thermoresistible__bu      VNSMVIRHSQPKYGAYKMAKAALLAMSQSLASELGEQGIRVNSVVPGYIW
MAB_4178c|M.abscessus_ATCC_199      INSMVIRHSQVRYGSYKIAKAALLAMSQSLATELGPQGVRVNSVVPGYMW
MLBr_02565|M.leprae_Br4923          LSSMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGFIE
                                    :.**.   .:        **: ::.::::**. *. :*: :*:* **:: 

Mb3560c|M.bovis_AF2122/97           GDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS
Rv3530c|M.tuberculosis_H37Rv        GDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS
MMAR_5018|M.marinum_M               GDTLQGYFEHQAGKYGTTVEQIYQATAAQSDLKRLPTEDEVASAILFMAS
MUL_4092|M.ulcerans_Agy99           GDTLQGYFEHQAGKYGTTVEKIYQATAAQSDLKRLPTEDEVASAVLFMAS
MAV_0630|M.avium_104                GDTLQAYFEHQAGKYGTTVEQIYAATAANSDLKRLPTEDEVASAIMFLAS
Mflv_1530|M.gilvum_PYR-GCK          GGTLESYFSHQAGKYGTTVDEIYKATAAASDLKRLPTEDEVASAILFMAC
Mvan_5228|M.vanbaalenii_PYR-1       GGTLESYFTHQAGKYGTTVEEIYKATAAASDLKRLPTEDEVASAILFMAS
MSMEG_5931|M.smegmatis_MC2_155      GGTLKSYFEHQAGKYGTSVEDIYNAAAAGSDLKRLPTEDEVASAILFMAS
TH_3268|M.thermoresistible__bu      GETLKGYFQHQAGKYNTTVDQIYQATAAQSDLKRLPTEDEVASAILFFAS
MAB_4178c|M.abscessus_ATCC_199      GENLKGYFEHQAKKYGGTVEQIYEYTAANSDLKRLPTTDEVANAVLFLAS
MLBr_02565|M.leprae_Br4923          T-QMTAAIPLATREVGRRLNSLLQGGLP----------VDVAETIAYFAI
                                       : . :   : : .  ::.:     .           :**.:: ::* 

Mb3560c|M.bovis_AF2122/97           DLASGITGQTLDVNCGEYHT-
Rv3530c|M.tuberculosis_H37Rv        DLASGITGQTLDVNCGEYHT-
MMAR_5018|M.marinum_M               DLSSGITGQTLDVNCGEYHT-
MUL_4092|M.ulcerans_Agy99           DLSSGITGQTLDVNCGEYHT-
MAV_0630|M.avium_104                DLSSGITGQTLDVNCGEYHT-
Mflv_1530|M.gilvum_PYR-GCK          DLSSGITGQALDVNCGEFKA-
Mvan_5228|M.vanbaalenii_PYR-1       DLSSGITGQALDVNCGEFKA-
MSMEG_5931|M.smegmatis_MC2_155      DLASGITGQALDVNCGEYKA-
TH_3268|M.thermoresistible__bu      DLSSGITGQTLDVNCGEYKV-
MAB_4178c|M.abscessus_ATCC_199      DLASGITGQALDVNCGEFHA-
MLBr_02565|M.leprae_Br4923          PASNAVTGNVIRVCGQAMLGA
                                      :..:**:.: *