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TGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDVAKQIIDTGRRAVAVRTDITDDDDV SNLVQATLAAYGKADVLINNAFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTPALAQSHGAIVNV NSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIWGDTLKSYFDHQAGKYGTTVDQ IYQATAANSDLKRLPTEDEVASAILFLASDLASGITGQTLDVNCGEYHT*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3530c | - | - | 100% (260) | short chain dehydrogenase |
M. tuberculosis H37Rv | Rv2766c | fabG | 3e-26 | 31.10% (254) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. tuberculosis H37Rv | Rv0927c | - | 5e-25 | 30.74% (257) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3560c | - | 1e-145 | 100.00% (260) | short chain dehydrogenase |
M. gilvum PYR-GCK | Mflv_1530 | - | 1e-112 | 77.25% (255) | short chain dehydrogenase |
M. leprae Br4923 | MLBr_01807 | fabG1 | 5e-17 | 28.51% (249) | 3-oxoacyl- |
M. abscessus ATCC 19977 | MAB_4178c | - | 2e-97 | 68.25% (252) | short chain dehydrogenase |
M. marinum M | MMAR_5018 | - | 1e-121 | 81.92% (260) | short-chain alcohol dehydrogenase |
M. avium 104 | MAV_0630 | - | 1e-122 | 83.27% (257) | short chain dehydrogenase |
M. smegmatis MC2 155 | MSMEG_5931 | - | 1e-113 | 77.13% (258) | short chain dehydrogenase |
M. thermoresistible (build 8) | TH_3268 | - | 1e-112 | 79.92% (254) | PUTATIVE short-chain dehydrogenase/reductase SDR |
M. ulcerans Agy99 | MUL_4092 | - | 1e-113 | 81.30% (246) | short chain dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_5228 | - | 1e-113 | 77.73% (256) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1530|M.gilvum_PYR-GCK MSEALPLLENKVVVISGVGPALGTTLARRCAEAGADLVLAARTVERLEDV Mvan_5228|M.vanbaalenii_PYR-1 --MAFGLLRDKVVVISGVGPALGTTLARRCAEEGADLVLAARTVERLDDV MSMEG_5931|M.smegmatis_MC2_155 ---MGGLLTDKVVVISGVGPALGTTLARRCAEQGADLVLAARTVERLEDV TH_3268|M.thermoresistible__bu --MTMLSLDNKVVVISGVGPALGTTLARRCAAAGADLVLAARTAERLEEV Rv3530c|M.tuberculosis_H37Rv ---MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDV Mb3560c|M.bovis_AF2122/97 ---MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDV MMAR_5018|M.marinum_M ---MPGLLDGKTLVISGVGPGLGTTLAHRCAAEGADLVLAARSGDRLDEL MUL_4092|M.ulcerans_Agy99 -----------------MGPGLGTTLAHRCAAEGADLVLAARIGDRLDEL MAV_0630|M.avium_104 ------MLDGKVVVISGVGPGLGTTLAHRCADSGADLVLAARTAERLEKV MAB_4178c|M.abscessus_ATCC_199 --MSLLNFDGKVVVVSGIGPGLGAALAIKFAEAGADVVLAARTQSRLDEV MLBr_01807|M.leprae_Br4923 ------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVAD * . : :: *.: :. ** Mflv_1530|M.gilvum_PYR-GCK ATQITDLGRRAVS------VGTDITDEAQVANLVEESLKAYGKVDVLINN Mvan_5228|M.vanbaalenii_PYR-1 ARQITDLGRRAVS------VGTDITDEAQVNNLVDESLKAYGKVDVLINN MSMEG_5931|M.smegmatis_MC2_155 AKQVTDTGRRALS------VGTDITDDAQVAHLVDETMKAYGRVDVVINN TH_3268|M.thermoresistible__bu AGQITATGRRAVA------VPTDITDEAQVANLVAETNKAYGRVDVLINN Rv3530c|M.tuberculosis_H37Rv AKQIIDTGRRAVA------VRTDITDDDDVSNLVQATLAAYGKADVLINN Mb3560c|M.bovis_AF2122/97 AKQIIDTGRRAVA------VRTDITDDDDVSNLVQATLAAYGKADVLINN MMAR_5018|M.marinum_M AKQIIDKGRQAIA------VRADITDDDQVSNLVDATLEAYGKIDVLVNN MUL_4092|M.ulcerans_Agy99 AKQIIDKGRQAIA------VRADITDDDQVSNLVDATLEAYGKIDVLVNN MAV_0630|M.avium_104 AKQVNDGGHRALA------VRTDITDDDEVAYLVETTMATYGRADVLINN MAB_4178c|M.abscessus_ATCC_199 ARQIAATGRRALA------VATDITDEASAANLVERATEEFGGIDVLVNN MLBr_01807|M.leprae_Br4923 GHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVAN . :: : :: * *:**: . * :*:: * Mflv_1530|M.gilvum_PYR-GCK AFRVPSMKPFANTTFEHMRDAIELTVFGALRMVQAFTP-ALAEANGAVVN Mvan_5228|M.vanbaalenii_PYR-1 AFRVPSMKPFADTTFEHMRDAIELTVFGALRMVQAFSP-ALAEANGAVVN MSMEG_5931|M.smegmatis_MC2_155 AFRVPSMKPFANTTFEHMRDAIELTVFGALRLIQGFTP-ALEESKGAVVN TH_3268|M.thermoresistible__bu AFRVPSMKPLANTGFDHIREAIELTVLGALRLTQALTP-ALAQANGSVVN Rv3530c|M.tuberculosis_H37Rv AFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTP-ALAQSHGAIVN Mb3560c|M.bovis_AF2122/97 AFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTP-ALAQSHGAIVN MMAR_5018|M.marinum_M AFRVPSMKPLAETTFQHIRDAIELSALGALRVIAGFTR-ALAETNGSIVN MUL_4092|M.ulcerans_Agy99 AFRVPSMKPLAETTFQHIRDAIELSALGALRVIAGFTR-ALAETNGSIVN MAV_0630|M.avium_104 AFRVPSMKPLAGTSFQHIRDAIELSALGALRLIQAFTP-ALETAHGSIVN MAB_4178c|M.abscessus_ATCC_199 AFSIPSMKSLEKTDYQHIRDSVELTVVGTLRLTQRVAA-ALAQSKGAVVN MLBr_01807|M.leprae_Br4923 AG-ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIF * :.* : ::::. :::. *.:*: : : * : Mflv_1530|M.gilvum_PYR-GCK VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGDQGIRVNSVLPGYIW Mvan_5228|M.vanbaalenii_PYR-1 VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGEQGIRVNSVLPGYIW MSMEG_5931|M.smegmatis_MC2_155 VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGEKGIRVNSVLPGYIW TH_3268|M.thermoresistible__bu VNSMVIRHSQPKYGAYKMAKAALLAMSQSLASELGEQGIRVNSVVPGYIW Rv3530c|M.tuberculosis_H37Rv VNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIW Mb3560c|M.bovis_AF2122/97 VNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIW MMAR_5018|M.marinum_M VNSMVLRHSQPKFGAYKMAKSTLLAMSHSLAAELGVKGIRVNSVAPGYIW MUL_4092|M.ulcerans_Agy99 VNSMVLRHSQPKFGADKTAKSTLLAMSHSLAAELGVKGIWVNSVAPGYIW MAV_0630|M.avium_104 VNSMVLRHSQAKYGAYKMAKSALLSMSQSLATELGEKGIRVNSVAPGYIW MAB_4178c|M.abscessus_ATCC_199 INSMVIRHSQVRYGSYKIAKAALLAMSQSLATELGPQGVRVNSVVPGYMW MLBr_01807|M.leprae_Br4923 MGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFID :.*:* . . :*: *:.*:::** *** :.: .* * **:: Mflv_1530|M.gilvum_PYR-GCK GGTLESYFSHQAGKYGTTVDEIYKATAAASDLKRLPTEDEVASAILFMAC Mvan_5228|M.vanbaalenii_PYR-1 GGTLESYFTHQAGKYGTTVEEIYKATAAASDLKRLPTEDEVASAILFMAS MSMEG_5931|M.smegmatis_MC2_155 GGTLKSYFEHQAGKYGTSVEDIYNAAAAGSDLKRLPTEDEVASAILFMAS TH_3268|M.thermoresistible__bu GETLKGYFQHQAGKYNTTVDQIYQATAAQSDLKRLPTEDEVASAILFFAS Rv3530c|M.tuberculosis_H37Rv GDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS Mb3560c|M.bovis_AF2122/97 GDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS MMAR_5018|M.marinum_M GDTLQGYFEHQAGKYGTTVEQIYQATAAQSDLKRLPTEDEVASAILFMAS MUL_4092|M.ulcerans_Agy99 GDTLQGYFEHQAGKYGTTVEKIYQATAAQSDLKRLPTEDEVASAVLFMAS MAV_0630|M.avium_104 GDTLQAYFEHQAGKYGTTVEQIYAATAANSDLKRLPTEDEVASAIMFLAS MAB_4178c|M.abscessus_ATCC_199 GENLKGYFEHQAKKYGGTVEQIYEYTAANSDLKRLPTTDEVANAVLFLAS MLBr_01807|M.leprae_Br4923 TEMTR-----------AMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLAS . .. : * *: : :*:*.*: *:*. Mflv_1530|M.gilvum_PYR-GCK DLSSGITGQALDVNCGEFKA- Mvan_5228|M.vanbaalenii_PYR-1 DLSSGITGQALDVNCGEFKA- MSMEG_5931|M.smegmatis_MC2_155 DLASGITGQALDVNCGEYKA- TH_3268|M.thermoresistible__bu DLSSGITGQTLDVNCGEYKV- Rv3530c|M.tuberculosis_H37Rv DLASGITGQTLDVNCGEYHT- Mb3560c|M.bovis_AF2122/97 DLASGITGQTLDVNCGEYHT- MMAR_5018|M.marinum_M DLSSGITGQTLDVNCGEYHT- MUL_4092|M.ulcerans_Agy99 DLSSGITGQTLDVNCGEYHT- MAV_0630|M.avium_104 DLSSGITGQTLDVNCGEYHT- MAB_4178c|M.abscessus_ATCC_199 DLASGITGQALDVNCGEFHA- MLBr_01807|M.leprae_Br4923 EDAGYISGAVIPVDGGLGMGH : :. *:* .: *: *