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M. tuberculosis H37Rv Rv3530c (-)

annotation: short chain dehydrogenase
coordinates: 3967038 - 3967820
length: 260

TGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDVAKQIIDTGRRAVAVRTDITDDDDV
SNLVQATLAAYGKADVLINNAFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTPALAQSHGAIVNV
NSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIWGDTLKSYFDHQAGKYGTTVDQ
IYQATAANSDLKRLPTEDEVASAILFLASDLASGITGQTLDVNCGEYHT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3530c--100% (260)short chain dehydrogenase
M. tuberculosis H37RvRv2766cfabG3e-2631.10% (254) 3-ketoacyl-(acyl-carrier-protein) reductase
M. tuberculosis H37RvRv0927c-5e-2530.74% (257) short chain dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3560c-1e-145100.00% (260) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1530-1e-11277.25% (255) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG15e-1728.51% (249) 3-oxoacyl-
M. abscessus ATCC 19977MAB_4178c-2e-9768.25% (252) short chain dehydrogenase
M. marinum MMMAR_5018-1e-12181.92% (260) short-chain alcohol dehydrogenase
M. avium 104MAV_0630-1e-12283.27% (257) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_5931-1e-11377.13% (258) short chain dehydrogenase
M. thermoresistible (build 8)TH_3268-1e-11279.92% (254) PUTATIVE short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_4092-1e-11381.30% (246) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_5228-1e-11377.73% (256) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1530|M.gilvum_PYR-GCK          MSEALPLLENKVVVISGVGPALGTTLARRCAEAGADLVLAARTVERLEDV
Mvan_5228|M.vanbaalenii_PYR-1       --MAFGLLRDKVVVISGVGPALGTTLARRCAEEGADLVLAARTVERLDDV
MSMEG_5931|M.smegmatis_MC2_155      ---MGGLLTDKVVVISGVGPALGTTLARRCAEQGADLVLAARTVERLEDV
TH_3268|M.thermoresistible__bu      --MTMLSLDNKVVVISGVGPALGTTLARRCAAAGADLVLAARTAERLEEV
Rv3530c|M.tuberculosis_H37Rv        ---MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDV
Mb3560c|M.bovis_AF2122/97           ---MTGMLKRKVIVVSGVGPGLGTTLAHRCARDGADLVLAARSAERLDDV
MMAR_5018|M.marinum_M               ---MPGLLDGKTLVISGVGPGLGTTLAHRCAAEGADLVLAARSGDRLDEL
MUL_4092|M.ulcerans_Agy99           -----------------MGPGLGTTLAHRCAAEGADLVLAARIGDRLDEL
MAV_0630|M.avium_104                ------MLDGKVVVISGVGPGLGTTLAHRCADSGADLVLAARTAERLEKV
MAB_4178c|M.abscessus_ATCC_199      --MSLLNFDGKVVVVSGIGPGLGAALAIKFAEAGADVVLAARTQSRLDEV
MLBr_01807|M.leprae_Br4923          ------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVAD
                                                      * .  : ::      *.:  :.     **   

Mflv_1530|M.gilvum_PYR-GCK          ATQITDLGRRAVS------VGTDITDEAQVANLVEESLKAYGKVDVLINN
Mvan_5228|M.vanbaalenii_PYR-1       ARQITDLGRRAVS------VGTDITDEAQVNNLVDESLKAYGKVDVLINN
MSMEG_5931|M.smegmatis_MC2_155      AKQVTDTGRRALS------VGTDITDDAQVAHLVDETMKAYGRVDVVINN
TH_3268|M.thermoresistible__bu      AGQITATGRRAVA------VPTDITDEAQVANLVAETNKAYGRVDVLINN
Rv3530c|M.tuberculosis_H37Rv        AKQIIDTGRRAVA------VRTDITDDDDVSNLVQATLAAYGKADVLINN
Mb3560c|M.bovis_AF2122/97           AKQIIDTGRRAVA------VRTDITDDDDVSNLVQATLAAYGKADVLINN
MMAR_5018|M.marinum_M               AKQIIDKGRQAIA------VRADITDDDQVSNLVDATLEAYGKIDVLVNN
MUL_4092|M.ulcerans_Agy99           AKQIIDKGRQAIA------VRADITDDDQVSNLVDATLEAYGKIDVLVNN
MAV_0630|M.avium_104                AKQVNDGGHRALA------VRTDITDDDEVAYLVETTMATYGRADVLINN
MAB_4178c|M.abscessus_ATCC_199      ARQIAATGRRALA------VATDITDEASAANLVERATEEFGGIDVLVNN
MLBr_01807|M.leprae_Br4923          GHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVAN
                                    . ::    : ::       *  *:**:      .       *  :*:: *

Mflv_1530|M.gilvum_PYR-GCK          AFRVPSMKPFANTTFEHMRDAIELTVFGALRMVQAFTP-ALAEANGAVVN
Mvan_5228|M.vanbaalenii_PYR-1       AFRVPSMKPFADTTFEHMRDAIELTVFGALRMVQAFSP-ALAEANGAVVN
MSMEG_5931|M.smegmatis_MC2_155      AFRVPSMKPFANTTFEHMRDAIELTVFGALRLIQGFTP-ALEESKGAVVN
TH_3268|M.thermoresistible__bu      AFRVPSMKPLANTGFDHIREAIELTVLGALRLTQALTP-ALAQANGSVVN
Rv3530c|M.tuberculosis_H37Rv        AFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTP-ALAQSHGAIVN
Mb3560c|M.bovis_AF2122/97           AFRVPSMKPLAGTTFEHIRDAIELSALGTLRLIQAFTP-ALAQSHGAIVN
MMAR_5018|M.marinum_M               AFRVPSMKPLAETTFQHIRDAIELSALGALRVIAGFTR-ALAETNGSIVN
MUL_4092|M.ulcerans_Agy99           AFRVPSMKPLAETTFQHIRDAIELSALGALRVIAGFTR-ALAETNGSIVN
MAV_0630|M.avium_104                AFRVPSMKPLAGTSFQHIRDAIELSALGALRLIQAFTP-ALETAHGSIVN
MAB_4178c|M.abscessus_ATCC_199      AFSIPSMKSLEKTDYQHIRDSVELTVVGTLRLTQRVAA-ALAQSKGAVVN
MLBr_01807|M.leprae_Br4923          AG-ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIF
                                    *  :.*   :     ::::. :::.  *.:*:    :   :    *  : 

Mflv_1530|M.gilvum_PYR-GCK          VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGDQGIRVNSVLPGYIW
Mvan_5228|M.vanbaalenii_PYR-1       VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGEQGIRVNSVLPGYIW
MSMEG_5931|M.smegmatis_MC2_155      VNSMVVRHSQAKYGAYKMAKSALLAMSQTLATELGEKGIRVNSVLPGYIW
TH_3268|M.thermoresistible__bu      VNSMVIRHSQPKYGAYKMAKAALLAMSQSLASELGEQGIRVNSVVPGYIW
Rv3530c|M.tuberculosis_H37Rv        VNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIW
Mb3560c|M.bovis_AF2122/97           VNSMVIRHSQPKYGTYKMAKSVLLAMSHSLATELGEQGIRVNSVAPGYIW
MMAR_5018|M.marinum_M               VNSMVLRHSQPKFGAYKMAKSTLLAMSHSLAAELGVKGIRVNSVAPGYIW
MUL_4092|M.ulcerans_Agy99           VNSMVLRHSQPKFGADKTAKSTLLAMSHSLAAELGVKGIWVNSVAPGYIW
MAV_0630|M.avium_104                VNSMVLRHSQAKYGAYKMAKSALLSMSQSLATELGEKGIRVNSVAPGYIW
MAB_4178c|M.abscessus_ATCC_199      INSMVIRHSQVRYGSYKIAKAALLAMSQSLATELGPQGVRVNSVVPGYMW
MLBr_01807|M.leprae_Br4923          MGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFID
                                    :.*:*   .    .    :*: *:.*:::** *** :.: .* * **:: 

Mflv_1530|M.gilvum_PYR-GCK          GGTLESYFSHQAGKYGTTVDEIYKATAAASDLKRLPTEDEVASAILFMAC
Mvan_5228|M.vanbaalenii_PYR-1       GGTLESYFTHQAGKYGTTVEEIYKATAAASDLKRLPTEDEVASAILFMAS
MSMEG_5931|M.smegmatis_MC2_155      GGTLKSYFEHQAGKYGTSVEDIYNAAAAGSDLKRLPTEDEVASAILFMAS
TH_3268|M.thermoresistible__bu      GETLKGYFQHQAGKYNTTVDQIYQATAAQSDLKRLPTEDEVASAILFFAS
Rv3530c|M.tuberculosis_H37Rv        GDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS
Mb3560c|M.bovis_AF2122/97           GDTLKSYFDHQAGKYGTTVDQIYQATAANSDLKRLPTEDEVASAILFLAS
MMAR_5018|M.marinum_M               GDTLQGYFEHQAGKYGTTVEQIYQATAAQSDLKRLPTEDEVASAILFMAS
MUL_4092|M.ulcerans_Agy99           GDTLQGYFEHQAGKYGTTVEKIYQATAAQSDLKRLPTEDEVASAVLFMAS
MAV_0630|M.avium_104                GDTLQAYFEHQAGKYGTTVEQIYAATAANSDLKRLPTEDEVASAIMFLAS
MAB_4178c|M.abscessus_ATCC_199      GENLKGYFEHQAKKYGGTVEQIYEYTAANSDLKRLPTTDEVANAVLFLAS
MLBr_01807|M.leprae_Br4923          TEMTR-----------AMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLAS
                                        .              ..    :     * *: : :*:*.*: *:*.

Mflv_1530|M.gilvum_PYR-GCK          DLSSGITGQALDVNCGEFKA-
Mvan_5228|M.vanbaalenii_PYR-1       DLSSGITGQALDVNCGEFKA-
MSMEG_5931|M.smegmatis_MC2_155      DLASGITGQALDVNCGEYKA-
TH_3268|M.thermoresistible__bu      DLSSGITGQTLDVNCGEYKV-
Rv3530c|M.tuberculosis_H37Rv        DLASGITGQTLDVNCGEYHT-
Mb3560c|M.bovis_AF2122/97           DLASGITGQTLDVNCGEYHT-
MMAR_5018|M.marinum_M               DLSSGITGQTLDVNCGEYHT-
MUL_4092|M.ulcerans_Agy99           DLSSGITGQTLDVNCGEYHT-
MAV_0630|M.avium_104                DLSSGITGQTLDVNCGEYHT-
MAB_4178c|M.abscessus_ATCC_199      DLASGITGQALDVNCGEFHA-
MLBr_01807|M.leprae_Br4923          EDAGYISGAVIPVDGGLGMGH
                                    : :. *:* .: *: *