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TAWRKAVQTLFRGRQIQLTLTASRAIESGRPEPLFVDSFAERLVLGSDDPYALALLETARAHPSSGSATG RTLFLARCRAVMTRHYDDALLAAAQSGATQVVLLAGGLDTRAYRLDWPAGVTVFEIDYPELLEFKDGVLA SVGAIPRTARRQVATFLSGPWQSDLTAAGFDPDLPTAWLAEALISHLPGPSHDALFERIIEMSALGSTIA TDTDGISPSGQSWADVRDALAAEAFNASELTRGYEERTRSSEWLSGHGWLAKTTTGRELADRYGLEPDAA LAPYVDEFDARRFLTATLPVSYLH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0125c | - | - | 100% (305) | hypothetical protein MAB_0125c |
| M. abscessus ATCC 19977 | MAB_4584c | - | 5e-51 | 38.11% (286) | hypothetical protein MAB_4584c |
| M. abscessus ATCC 19977 | MAB_4585c | - | 1e-47 | 39.51% (286) | hypothetical protein MAB_4585c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0150 | - | 2e-46 | 40.61% (261) | hypothetical protein Mb0150 |
| M. gilvum PYR-GCK | Mflv_0743 | - | 3e-41 | 36.47% (266) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0145 | - | 2e-46 | 40.61% (261) | hypothetical protein Rv0145 |
| M. leprae Br4923 | MLBr_02020 | - | 4e-45 | 39.10% (289) | hypothetical protein MLBr_02020 |
| M. marinum M | MMAR_0356 | - | 1e-42 | 38.70% (292) | hypothetical protein MMAR_0356 |
| M. avium 104 | MAV_5150 | - | 7e-44 | 38.85% (260) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1482 | - | 7e-41 | 39.56% (273) | methyltransferase |
| M. thermoresistible (build 8) | TH_2759 | - | 6e-43 | 37.59% (266) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_4763 | - | 2e-42 | 38.83% (291) | hypothetical protein MUL_4763 |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 3e-43 | 38.26% (264) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0150|M.bovis_AF2122/97 ---MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNP
Rv0145|M.tuberculosis_H37Rv ---MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNP
MMAR_0356|M.marinum_M ---MTELDEVDSLRSD----GDSWTVTESVGATALGVAAARAVETAGANP
MUL_4763|M.ulcerans_Agy99 ---MTELDEVDSLRSD----GDSWTVTESVGATALGVAAARAVETAGANP
MAV_5150|M.avium_104 ---MTDLD--SSLPPSVRTAGDSWTITELVGATALGVAAARAAETAGPDP
TH_2759|M.thermoresistible__bu MVMMFDVTEAASARSE----GDSWDITESVGATALGVAAERALETSQPDP
Mflv_0743|M.gilvum_PYR-GCK ---------MSSLRTD----DDTWDIASSVGATAVMVAAARAAETERHDA
Mvan_0104|M.vanbaalenii_PYR-1 ---------MSSLRTD----NDTWDIASSVGATAVMVAAARAAETERPEP
MSMEG_1482|M.smegmatis_MC2_155 -----------MARTE----NDTWDLASSVGATATMVAAARALATNADEP
MLBr_02020|M.leprae_Br4923 --MMAATPEFGSLRSD----DDHWDIVSSVGYTALLVAGWRALHAVGPQP
MAB_0125c|M.abscessus_ATCC_199 ---------MTAWRKA-------VQTLFRGRQIQLTLTASRAIESGRPEP
::. ** : :.
Mb0150|M.bovis_AF2122/97 LIRDEFAKVLVSSAGT-AWARLADADLAWLD--GDQLGRRVHRVACDYQA
Rv0145|M.tuberculosis_H37Rv LIRDEFAKVLVSSAGT-AWARLADADLAWLD--GDQLGRRVHRVACDYQA
MMAR_0356|M.marinum_M LIRDEFAPILVSSAGP-AWARLADPDIGWLD--DDPHGQRLHRLGCDYQA
MUL_4763|M.ulcerans_Agy99 LIRDEFAPILVSSAGP-AWARLADPDIGWLD--DDPHGQRLHRLGCDYQA
MAV_5150|M.avium_104 LIRDEFAGLLVSSAGP-AWARLADPEQSWLD--DDPHGKRAHRVGIDYQA
TH_2759|M.thermoresistible__bu LIRDEYAFLLVSAAGP-PWTQLASSDLSWLG--DDETARRMHLMSRDYQA
Mflv_0743|M.gilvum_PYR-GCK LINDPYAKVLVEGAGAGAWRFIADEDLVAKASESDTEVGALFEHMKNYQA
Mvan_0104|M.vanbaalenii_PYR-1 LIDDPYAKILVAGAGNGAWQYIADDGFVAKVTESDPEIGPLFEHMKNYQA
MSMEG_1482|M.smegmatis_MC2_155 AIDDPFAAPLVRAVGVDFFTKLVDDNFDLTA--LDPEAAEGLTRFANGMA
MLBr_02020|M.leprae_Br4923 LVRDEYAKYFITASRDPYLMNLLANPGTSLN---ETAFPRLY-------G
MAB_0125c|M.abscessus_ATCC_199 LFVDSFAERLVLGSDDPYALALLETARAHPS---SGSATGRTLFLARCRA
. * :* :: . : . .
Mb0150|M.bovis_AF2122/97 VRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQPS
Rv0145|M.tuberculosis_H37Rv VRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQPS
MMAR_0356|M.marinum_M VRTHFFDEYFAAAAGAGIEQAVILAAGLDCRAYRLNWPPEAVVFEIDQPK
MUL_4763|M.ulcerans_Agy99 VRTHFSDEYFAAAAGAGIEQAVILAAGLDCRAYRLNWPPEAVVFEIDQPK
MAV_5150|M.avium_104 VRTHYFDEYFDGALRAGIRQVVILAAGLDSRAYRLNWPAGTTVYEIDQPK
TH_2759|M.thermoresistible__bu VRTHYFDRYFAAAARAGIRQIVLLAAGLDSRAYRLDWPAGTVVYELDQPR
Mflv_0743|M.gilvum_PYR-GCK VRTHFFDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPL
Mvan_0104|M.vanbaalenii_PYR-1 VRTHFFDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPL
MSMEG_1482|M.smegmatis_MC2_155 ARTRFFDDFFLDAARAGVRQFVILASGLDARAYRLPWPAGSVVFEIDQPD
MLBr_02020|M.leprae_Br4923 VQTRFFDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPK
MAB_0125c|M.abscessus_ATCC_199 VMTRHYDDALLAAAQSGATQVVLLAGGLDTRAYRLDWPAGVTVFEIDYPE
. *:. * : * :* * *::*.*** **:** ** .*:*:* *
Mb0150|M.bovis_AF2122/97 VLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWLA
Rv0145|M.tuberculosis_H37Rv VLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWLA
MMAR_0356|M.marinum_M VLEYKAQILESHGVTAAATRHGVAVDLREDWPAALLRAGFDRDRPTAWLA
MUL_4763|M.ulcerans_Agy99 VLEYKAQILESHGVTAAATRHGVAVDLREDWPAALLRAGFDRDRPTAWLA
MAV_5150|M.avium_104 VLEYKTETLQRHGATPAAVRRPVPVDLRDDWPAALTAAGFQAARPTAWLA
TH_2759|M.thermoresistible__bu VLDFKNRTLQAHGAVAKADRRTVAVDLRDDWPAALRHAGFDSAAPTAWLA
Mflv_0743|M.gilvum_PYR-GCK VLDYKSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLA
Mvan_0104|M.vanbaalenii_PYR-1 VLAYKSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLA
MSMEG_1482|M.smegmatis_MC2_155 VIEFKTKALADLGALPTTDRRAVAVDLRFDWPAALTEAGFDPAEPTAWIA
MLBr_02020|M.leprae_Br4923 VLEFKARVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSV
MAB_0125c|M.abscessus_ATCC_199 LLEFKDGVLASVGAIPRTARRQVATFLSGPWQSDLTAAGFDPDLPTAWLA
:: :* * *. . : * *. * * * :**: .:** .
Mb0150|M.bovis_AF2122/97 EGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGNTQR----WN
Rv0145|M.tuberculosis_H37Rv EGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGNTQR----WN
MMAR_0356|M.marinum_M EGLLPYLPGDAQDRLFEMITDLSAPRSRIAVESFTMNLTGNKQR----WN
MUL_4763|M.ulcerans_Agy99 EGLLPYLPGDAQDRLFEMITDLSAPRSRIAVESFTMNLTGNKQR----WN
MAV_5150|M.avium_104 EGLLPYLPSDAQDRLFEMVTALSAAGSQVAVEVFGMNSRSNAQR----WL
TH_2759|M.thermoresistible__bu EGLLCYLPADAQDRLFERITALSAPGSWLAVEAFHHDPQRATERRRAEWR
Mflv_0743|M.gilvum_PYR-GCK EGLLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAPDRRER----MR
Mvan_0104|M.vanbaalenii_PYR-1 EGLLMYLPADAQDRLFAQITELSAPGSRVAAESMGIHAQDRRER----MR
MSMEG_1482|M.smegmatis_MC2_155 EGLLGYLPPEAQDRLLDQIAELSAPGSRVAVEEIPAIEEEDHEEIAARMK
MLBr_02020|M.leprae_Br4923 EGLLPYLTNDAQSALFTRIGELCAPGSRIAVGALGSRLDRKQLA------
MAB_0125c|M.abscessus_ATCC_199 EALISHLPGPSHDALFERIIEMSALGSTIATDTDGISPSGQSWA------
*.*: :*. : . *: : :.* * :*.
Mb0150|M.bovis_AF2122/97 ----RMRERLGLD----IDVQALTYHEPDRSDAAQWLATHGWQVHSVSNR
Rv0145|M.tuberculosis_H37Rv ----RMRERLGLD----IDVQALTYHEPDRSDAAQWLATHGWQVHSVSNR
MMAR_0356|M.marinum_M ----RMRDRLGLD----INVEALTYREPGRADAAEWLANHGWQVYSVSNR
MUL_4763|M.ulcerans_Agy99 ----RMRDRLGLD----INVEALTYREPGRTDAAEWLANHGWQVYSVSNR
MAV_5150|M.avium_104 ----RMRERLGLD----VNVAALTYHEPDRSDAAAWLTGHGWRVHSVDNR
TH_2759|M.thermoresistible__bu DRTARMKAALDLN----LDFEALTYDDPDRADAGEWLAAHGWHPDSVPGT
Mflv_0743|M.gilvum_PYR-GCK ERFASIASQIDIEP---MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQ
Mvan_0104|M.vanbaalenii_PYR-1 ERFASITAQFDVEP---MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQ
MSMEG_1482|M.smegmatis_MC2_155 DFSDRWRAH-GFD----LDFTELVFLG-DRADVSSYLQGHGWKTTSMTSD
MLBr_02020|M.leprae_Br4923 ---ALEATHPGVNISGDVDFSALTYEP--KTDSAQWLAAHGWAVEPVRNT
MAB_0125c|M.abscessus_ATCC_199 ----DVRDALAAEA---FNASELTRGYEERTRSSEWLSGHGWLAKTTTGR
: .: *. :: . :* *** . .
Mb0150|M.bovis_AF2122/97 EEMARLGRA---IPQDLVDETVRTTLLRGRLVTPAQPA
Rv0145|M.tuberculosis_H37Rv EEMARLGRA---IPQDLVDETVRTTLLRGRLVTPAQPA
MMAR_0356|M.marinum_M EEMARLGRP---VPEDLVDEAITTTLLRASLEISR---
MUL_4763|M.ulcerans_Agy99 EEMARLGRP---VPEDLVDEAITTTLLRASLEILR---
MAV_5150|M.avium_104 DEMARLGRP---VPEDLSDEAVRSTLLRAHLGGSTG--
TH_2759|M.thermoresistible__bu EEMARMGRP---VPADLLDVAVPSTLLRAHLNGASR--
Mflv_0743|M.gilvum_PYR-GCK DAMRRLDRY---VEVADSDGQSFSTFTTGTKL------
Mvan_0104|M.vanbaalenii_PYR-1 DEMRRLHRL---VEIADGDDQSFSTFTTAVKR------
MSMEG_1482|M.smegmatis_MC2_155 ELLVHNG-----LPRVDDDAQIGSVVYVTATR------
MLBr_02020|M.leprae_Br4923 LELQTSYGM---TPPD-VDVQMDSFMHSQYITATR---
MAB_0125c|M.abscessus_ATCC_199 ELADRYGLEPDAALAPYVDEFDARRFLTATLPVSYLH-
* .