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M. avium 104 MAV_5150 (-)

annotation: methyltransferase, putative, family protein
coordinates: 5301217 - 5302158
length: 313

TDLDSSLPPSVRTAGDSWTITELVGATALGVAAARAAETAGPDPLIRDEFAGLLVSSAGPAWARLADPEQ
SWLDDDPHGKRAHRVGIDYQAVRTHYFDEYFDGALRAGIRQVVILAAGLDSRAYRLNWPAGTTVYEIDQP
KVLEYKTETLQRHGATPAAVRRPVPVDLRDDWPAALTAAGFQAARPTAWLAEGLLPYLPSDAQDRLFEMV
TALSAAGSQVAVEVFGMNSRSNAQRWLRMRERLGLDVNVAALTYHEPDRSDAAAWLTGHGWRVHSVDNRD
EMARLGRPVPEDLSDEAVRSTLLRAHLGGSTG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_5150--100% (313)methyltransferase, putative, family protein
M. avium 104MAV_5149-1e-7653.45% (290) methyltransferase, putative, family protein
M. avium 104MAV_4442-1e-6850.53% (285) methyltransferase, putative, family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0150-1e-13274.52% (310) hypothetical protein Mb0150
M. gilvum PYR-GCKMflv_0743-8e-8053.44% (305) putative methyltransferase
M. tuberculosis H37RvRv0145-1e-13274.52% (310) hypothetical protein Rv0145
M. leprae Br4923MLBr_02640-1e-7353.31% (287) hypothetical protein MLBr_02640
M. abscessus ATCC 19977MAB_4607c-2e-8555.52% (308) hypothetical protein MAB_4607c
M. marinum MMMAR_0356-1e-12772.40% (308) hypothetical protein MMAR_0356
M. smegmatis MC2 155MSMEG_0093-1e-10763.64% (319) methyltransferase
M. thermoresistible (build 8)TH_2759-1e-10963.87% (310) PUTATIVE methyltransferase
M. ulcerans Agy99MUL_4763-1e-12772.08% (308) hypothetical protein MUL_4763
M. vanbaalenii PYR-1Mvan_0104-2e-8254.40% (307) putative methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0150|M.bovis_AF2122/97            ---MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNP
Rv0145|M.tuberculosis_H37Rv         ---MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNP
MMAR_0356|M.marinum_M               ---MTELDEVDSLRSD----GDSWTVTESVGATALGVAAARAVETAGANP
MUL_4763|M.ulcerans_Agy99           ---MTELDEVDSLRSD----GDSWTVTESVGATALGVAAARAVETAGANP
MAV_5150|M.avium_104                ---MTDLD--SSLPPSVRTAGDSWTITELVGATALGVAAARAAETAGPDP
MSMEG_0093|M.smegmatis_MC2_155      ---MTDVRETPSVRSA----RDSWGITESVGATALGVAAARAAETAQADP
TH_2759|M.thermoresistible__bu      MVMMFDVTEAASARSE----GDSWDITESVGATALGVAAERALETSQPDP
MAB_4607c|M.abscessus_ATCC_199      ------------MRVD----GDTWDITSSVGATALGVAAARATETLRADA
Mflv_0743|M.gilvum_PYR-GCK          ---------MSSLRTD----DDTWDIASSVGATAVMVAAARAAETERHDA
Mvan_0104|M.vanbaalenii_PYR-1       ---------MSSLRTD----NDTWDIASSVGATAVMVAAARAAETERPEP
MLBr_02640|M.leprae_Br4923          ------------MRTH----DDTWDIKTSVGTTAVMVAAARAAETDRPDA
                                                         *:* :   **:**: *** ** **   :.

Mb0150|M.bovis_AF2122/97            LIRDEFAKVLVSSAG--TAWARLADA--DLAWLDGDQLGRRVHRVACDYQ
Rv0145|M.tuberculosis_H37Rv         LIRDEFAKVLVSSAG--TAWARLADA--DLAWLDGDQLGRRVHRVACDYQ
MMAR_0356|M.marinum_M               LIRDEFAPILVSSAG--PAWARLADP--DIGWLDDDPHGQRLHRLGCDYQ
MUL_4763|M.ulcerans_Agy99           LIRDEFAPILVSSAG--PAWARLADP--DIGWLDDDPHGQRLHRLGCDYQ
MAV_5150|M.avium_104                LIRDEFAGLLVSSAG--PAWARLADP--EQSWLDDDPHGKRAHRVGIDYQ
MSMEG_0093|M.smegmatis_MC2_155      LIRDEFAFLLVSAAG--PTWAQMAVS--DPHWLGADADARRIHEISRNYQ
TH_2759|M.thermoresistible__bu      LIRDEYAFLLVSAAG--PPWTQLASS--DLSWLGDDETARRMHLMSRDYQ
MAB_4607c|M.abscessus_ATCC_199      LIRDPFAQILVDATGKATGWERLVAG--DIDWP--DPEAGRIYDRMVDYQ
Mflv_0743|M.gilvum_PYR-GCK          LINDPYAKVLVEGAGAGA-WRFIADEDLVAKASESDTEVGALFEHMKNYQ
Mvan_0104|M.vanbaalenii_PYR-1       LIDDPYAKILVAGAGNGA-WQYIADDGFVAKVTESDPEIGPLFEHMKNYQ
MLBr_02640|M.leprae_Br4923          LIRDPYAKLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQ
                                    ** * :* :**  :*  . *  :            *           .**

Mb0150|M.bovis_AF2122/97            AVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQP
Rv0145|M.tuberculosis_H37Rv         AVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQP
MMAR_0356|M.marinum_M               AVRTHFFDEYFAAAAGAGIEQAVILAAGLDCRAYRLNWPPEAVVFEIDQP
MUL_4763|M.ulcerans_Agy99           AVRTHFSDEYFAAAAGAGIEQAVILAAGLDCRAYRLNWPPEAVVFEIDQP
MAV_5150|M.avium_104                AVRTHYFDEYFDGALRAGIRQVVILAAGLDSRAYRLNWPAGTTVYEIDQP
MSMEG_0093|M.smegmatis_MC2_155      AVRTHYFDEYFSDVAHAGIRQVVILAAGLDSRAFRLDWPAGTTVFEIDQP
TH_2759|M.thermoresistible__bu      AVRTHYFDRYFAAAARAGIRQIVLLAAGLDSRAYRLDWPAGTVVYELDQP
MAB_4607c|M.abscessus_ATCC_199      ATRTHFFDEYFLAAAAAGIRQVVILASGLDSRAYRLDWPAGTTVYEIDQP
Mflv_0743|M.gilvum_PYR-GCK          AVRTHFFDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQP
Mvan_0104|M.vanbaalenii_PYR-1       AVRTHFFDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQP
MLBr_02640|M.leprae_Br4923          AVRTNFFDTYFNNAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQP
                                    *.**:: * :*  .   *:.* *:**:***.**:** **. :.*:*:***

Mb0150|M.bovis_AF2122/97            SVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWL
Rv0145|M.tuberculosis_H37Rv         SVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWL
MMAR_0356|M.marinum_M               KVLEYKAQILESHGVTAAATRHGVAVDLREDWPAALLRAGFDRDRPTAWL
MUL_4763|M.ulcerans_Agy99           KVLEYKAQILESHGVTAAATRHGVAVDLREDWPAALLRAGFDRDRPTAWL
MAV_5150|M.avium_104                KVLEYKTETLQRHGATPAAVRRPVPVDLRDDWPAALTAAGFQAARPTAWL
MSMEG_0093|M.smegmatis_MC2_155      KVLEYKTATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQPTAWL
TH_2759|M.thermoresistible__bu      RVLDFKNRTLQAHGAVAKADRRTVAVDLRDDWPAALRHAGFDSAAPTAWL
MAB_4607c|M.abscessus_ATCC_199      QVLKFKDSALAAH--QPTAQRRGVAIDLREDWPAALRAAGFDSAQPTAWL
Mflv_0743|M.gilvum_PYR-GCK          LVLDYKSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWL
Mvan_0104|M.vanbaalenii_PYR-1       LVLAYKSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWL
MLBr_02640|M.leprae_Br4923          KVLAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWL
                                     ** :*   *  *   . *    *. ***:***.**  :**:    ****

Mb0150|M.bovis_AF2122/97            AEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKG-NTQ-----
Rv0145|M.tuberculosis_H37Rv         AEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKG-NTQ-----
MMAR_0356|M.marinum_M               AEGLLPYLPGDAQDRLFEMITDLSAPRSRIAVESFTMNLTG-NKQ-----
MUL_4763|M.ulcerans_Agy99           AEGLLPYLPGDAQDRLFEMITDLSAPRSRIAVESFTMNLTG-NKQ-----
MAV_5150|M.avium_104                AEGLLPYLPSDAQDRLFEMVTALSAAGSQVAVEVFGMNSRS-NAQ-----
MSMEG_0093|M.smegmatis_MC2_155      AEGLLPYLPADAQDRLFELVGVNSAPGSRIAVEAFNMSPER-YTEERRAQ
TH_2759|M.thermoresistible__bu      AEGLLCYLPADAQDRLFERITALSAPGSWLAVEAFHHDPQR-ATERRRAE
MAB_4607c|M.abscessus_ATCC_199      AEGLLPYLPADAQDNLFRDIGVLSAAGSRVAVEGYEGKLVLDESEEEAVR
Mflv_0743|M.gilvum_PYR-GCK          AEGLLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAPDRRER-----
Mvan_0104|M.vanbaalenii_PYR-1       AEGLLMYLPADAQDRLFAQITELSAPGSRVAAESMGIHAQDRRER-----
MLBr_02640|M.leprae_Br4923          AEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQ-----
                                    ***** ***. * * **  :   **  * :*.*           .     

Mb0150|M.bovis_AF2122/97            ---RWNRMRERLGLDI--DVQALTYHEPDRSDAAQWLATHGWQVHSVSNR
Rv0145|M.tuberculosis_H37Rv         ---RWNRMRERLGLDI--DVQALTYHEPDRSDAAQWLATHGWQVHSVSNR
MMAR_0356|M.marinum_M               ---RWNRMRDRLGLDI--NVEALTYREPGRADAAEWLANHGWQVYSVSNR
MUL_4763|M.ulcerans_Agy99           ---RWNRMRDRLGLDI--NVEALTYREPGRTDAAEWLANHGWQVYSVSNR
MAV_5150|M.avium_104                ---RWLRMRERLGLDV--NVAALTYHEPDRSDAAAWLTGHGWRVHSVDNR
MSMEG_0093|M.smegmatis_MC2_155      RRARGEQMRKQLDLDI--DVDALMYTADDRADAAQWLSEHGWQVEAVPSA
TH_2759|M.thermoresistible__bu      WRDRTARMKAALDLNL--DFEALTYDDPDRADAGEWLAAHGWHPDSVPGT
MAB_4607c|M.abscessus_ATCC_199      REQVRAAFKTAIDVDV--TIENLIYEDENRADPAEWLDAHGWSVTKTDAH
Mflv_0743|M.gilvum_PYR-GCK          MRERFASIASQIDIEP-MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQ
Mvan_0104|M.vanbaalenii_PYR-1       MRERFASITAQFDVEP-MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQ
MLBr_02640|M.leprae_Br4923          MQLRFRRVSDALGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAP
                                           .   :..:    .  * *   .*:  . **  ***        

Mb0150|M.bovis_AF2122/97            EEMARLGRA---IPQDLVDETVRTTLLRGRLVTPAQPA
Rv0145|M.tuberculosis_H37Rv         EEMARLGRA---IPQDLVDETVRTTLLRGRLVTPAQPA
MMAR_0356|M.marinum_M               EEMARLGRP---VPEDLVDEAITTTLLRASLEISR---
MUL_4763|M.ulcerans_Agy99           EEMARLGRP---VPEDLVDEAITTTLLRASLEILR---
MAV_5150|M.avium_104                DEMARLGRP---VPEDLSDEAVRSTLLRAHLGGSTG--
MSMEG_0093|M.smegmatis_MC2_155      DEMARLGRPA--AEADLAEFGMDGVLMRARLDGERL--
TH_2759|M.thermoresistible__bu      EEMARMGRP---VPADLLDVAVPSTLLRAHLNGASR--
MAB_4607c|M.abscessus_ATCC_199      DEMARLGRP---VAEDVERGTFRGQLIQGELR------
Mflv_0743|M.gilvum_PYR-GCK          DAMRRLDRY---VEVADSDGQSFSTFTTGTKL------
Mvan_0104|M.vanbaalenii_PYR-1       DEMRRLHRL---VEIADGDDQSFSTFTTAVKR------
MLBr_02640|M.leprae_Br4923          DEMRRVGRWGDGVPMAD-DKDAFAEFVTAHRL------
                                    : * *: *                 :  .