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TDLDSSLPPSVRTAGDSWTITELVGATALGVAAARAAETAGPDPLIRDEFAGLLVSSAGPAWARLADPEQ SWLDDDPHGKRAHRVGIDYQAVRTHYFDEYFDGALRAGIRQVVILAAGLDSRAYRLNWPAGTTVYEIDQP KVLEYKTETLQRHGATPAAVRRPVPVDLRDDWPAALTAAGFQAARPTAWLAEGLLPYLPSDAQDRLFEMV TALSAAGSQVAVEVFGMNSRSNAQRWLRMRERLGLDVNVAALTYHEPDRSDAAAWLTGHGWRVHSVDNRD EMARLGRPVPEDLSDEAVRSTLLRAHLGGSTG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_5150 | - | - | 100% (313) | methyltransferase, putative, family protein |
M. avium 104 | MAV_5149 | - | 1e-76 | 53.45% (290) | methyltransferase, putative, family protein |
M. avium 104 | MAV_4442 | - | 1e-68 | 50.53% (285) | methyltransferase, putative, family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0150 | - | 1e-132 | 74.52% (310) | hypothetical protein Mb0150 |
M. gilvum PYR-GCK | Mflv_0743 | - | 8e-80 | 53.44% (305) | putative methyltransferase |
M. tuberculosis H37Rv | Rv0145 | - | 1e-132 | 74.52% (310) | hypothetical protein Rv0145 |
M. leprae Br4923 | MLBr_02640 | - | 1e-73 | 53.31% (287) | hypothetical protein MLBr_02640 |
M. abscessus ATCC 19977 | MAB_4607c | - | 2e-85 | 55.52% (308) | hypothetical protein MAB_4607c |
M. marinum M | MMAR_0356 | - | 1e-127 | 72.40% (308) | hypothetical protein MMAR_0356 |
M. smegmatis MC2 155 | MSMEG_0093 | - | 1e-107 | 63.64% (319) | methyltransferase |
M. thermoresistible (build 8) | TH_2759 | - | 1e-109 | 63.87% (310) | PUTATIVE methyltransferase |
M. ulcerans Agy99 | MUL_4763 | - | 1e-127 | 72.08% (308) | hypothetical protein MUL_4763 |
M. vanbaalenii PYR-1 | Mvan_0104 | - | 2e-82 | 54.40% (307) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0150|M.bovis_AF2122/97 ---MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNP Rv0145|M.tuberculosis_H37Rv ---MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNP MMAR_0356|M.marinum_M ---MTELDEVDSLRSD----GDSWTVTESVGATALGVAAARAVETAGANP MUL_4763|M.ulcerans_Agy99 ---MTELDEVDSLRSD----GDSWTVTESVGATALGVAAARAVETAGANP MAV_5150|M.avium_104 ---MTDLD--SSLPPSVRTAGDSWTITELVGATALGVAAARAAETAGPDP MSMEG_0093|M.smegmatis_MC2_155 ---MTDVRETPSVRSA----RDSWGITESVGATALGVAAARAAETAQADP TH_2759|M.thermoresistible__bu MVMMFDVTEAASARSE----GDSWDITESVGATALGVAAERALETSQPDP MAB_4607c|M.abscessus_ATCC_199 ------------MRVD----GDTWDITSSVGATALGVAAARATETLRADA Mflv_0743|M.gilvum_PYR-GCK ---------MSSLRTD----DDTWDIASSVGATAVMVAAARAAETERHDA Mvan_0104|M.vanbaalenii_PYR-1 ---------MSSLRTD----NDTWDIASSVGATAVMVAAARAAETERPEP MLBr_02640|M.leprae_Br4923 ------------MRTH----DDTWDIKTSVGTTAVMVAAARAAETDRPDA *:* : **:**: *** ** ** :. Mb0150|M.bovis_AF2122/97 LIRDEFAKVLVSSAG--TAWARLADA--DLAWLDGDQLGRRVHRVACDYQ Rv0145|M.tuberculosis_H37Rv LIRDEFAKVLVSSAG--TAWARLADA--DLAWLDGDQLGRRVHRVACDYQ MMAR_0356|M.marinum_M LIRDEFAPILVSSAG--PAWARLADP--DIGWLDDDPHGQRLHRLGCDYQ MUL_4763|M.ulcerans_Agy99 LIRDEFAPILVSSAG--PAWARLADP--DIGWLDDDPHGQRLHRLGCDYQ MAV_5150|M.avium_104 LIRDEFAGLLVSSAG--PAWARLADP--EQSWLDDDPHGKRAHRVGIDYQ MSMEG_0093|M.smegmatis_MC2_155 LIRDEFAFLLVSAAG--PTWAQMAVS--DPHWLGADADARRIHEISRNYQ TH_2759|M.thermoresistible__bu LIRDEYAFLLVSAAG--PPWTQLASS--DLSWLGDDETARRMHLMSRDYQ MAB_4607c|M.abscessus_ATCC_199 LIRDPFAQILVDATGKATGWERLVAG--DIDWP--DPEAGRIYDRMVDYQ Mflv_0743|M.gilvum_PYR-GCK LINDPYAKVLVEGAGAGA-WRFIADEDLVAKASESDTEVGALFEHMKNYQ Mvan_0104|M.vanbaalenii_PYR-1 LIDDPYAKILVAGAGNGA-WQYIADDGFVAKVTESDPEIGPLFEHMKNYQ MLBr_02640|M.leprae_Br4923 LIRDPYAKLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQ ** * :* :** :* . * : * .** Mb0150|M.bovis_AF2122/97 AVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQP Rv0145|M.tuberculosis_H37Rv AVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQP MMAR_0356|M.marinum_M AVRTHFFDEYFAAAAGAGIEQAVILAAGLDCRAYRLNWPPEAVVFEIDQP MUL_4763|M.ulcerans_Agy99 AVRTHFSDEYFAAAAGAGIEQAVILAAGLDCRAYRLNWPPEAVVFEIDQP MAV_5150|M.avium_104 AVRTHYFDEYFDGALRAGIRQVVILAAGLDSRAYRLNWPAGTTVYEIDQP MSMEG_0093|M.smegmatis_MC2_155 AVRTHYFDEYFSDVAHAGIRQVVILAAGLDSRAFRLDWPAGTTVFEIDQP TH_2759|M.thermoresistible__bu AVRTHYFDRYFAAAARAGIRQIVLLAAGLDSRAYRLDWPAGTVVYELDQP MAB_4607c|M.abscessus_ATCC_199 ATRTHFFDEYFLAAAAAGIRQVVILASGLDSRAYRLDWPAGTTVYEIDQP Mflv_0743|M.gilvum_PYR-GCK AVRTHFFDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQP Mvan_0104|M.vanbaalenii_PYR-1 AVRTHFFDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQP MLBr_02640|M.leprae_Br4923 AVRTNFFDTYFNNAVIDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQP *.**:: * :* . *:.* *:**:***.**:** **. :.*:*:*** Mb0150|M.bovis_AF2122/97 SVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWL Rv0145|M.tuberculosis_H37Rv SVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWL MMAR_0356|M.marinum_M KVLEYKAQILESHGVTAAATRHGVAVDLREDWPAALLRAGFDRDRPTAWL MUL_4763|M.ulcerans_Agy99 KVLEYKAQILESHGVTAAATRHGVAVDLREDWPAALLRAGFDRDRPTAWL MAV_5150|M.avium_104 KVLEYKTETLQRHGATPAAVRRPVPVDLRDDWPAALTAAGFQAARPTAWL MSMEG_0093|M.smegmatis_MC2_155 KVLEYKTATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQPTAWL TH_2759|M.thermoresistible__bu RVLDFKNRTLQAHGAVAKADRRTVAVDLRDDWPAALRHAGFDSAAPTAWL MAB_4607c|M.abscessus_ATCC_199 QVLKFKDSALAAH--QPTAQRRGVAIDLREDWPAALRAAGFDSAQPTAWL Mflv_0743|M.gilvum_PYR-GCK LVLDYKSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWL Mvan_0104|M.vanbaalenii_PYR-1 LVLAYKSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWL MLBr_02640|M.leprae_Br4923 KVLAYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWL ** :* * * . * *. ***:***.** :**: **** Mb0150|M.bovis_AF2122/97 AEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKG-NTQ----- Rv0145|M.tuberculosis_H37Rv AEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKG-NTQ----- MMAR_0356|M.marinum_M AEGLLPYLPGDAQDRLFEMITDLSAPRSRIAVESFTMNLTG-NKQ----- MUL_4763|M.ulcerans_Agy99 AEGLLPYLPGDAQDRLFEMITDLSAPRSRIAVESFTMNLTG-NKQ----- MAV_5150|M.avium_104 AEGLLPYLPSDAQDRLFEMVTALSAAGSQVAVEVFGMNSRS-NAQ----- MSMEG_0093|M.smegmatis_MC2_155 AEGLLPYLPADAQDRLFELVGVNSAPGSRIAVEAFNMSPER-YTEERRAQ TH_2759|M.thermoresistible__bu AEGLLCYLPADAQDRLFERITALSAPGSWLAVEAFHHDPQR-ATERRRAE MAB_4607c|M.abscessus_ATCC_199 AEGLLPYLPADAQDNLFRDIGVLSAAGSRVAVEGYEGKLVLDESEEEAVR Mflv_0743|M.gilvum_PYR-GCK AEGLLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAPDRRER----- Mvan_0104|M.vanbaalenii_PYR-1 AEGLLMYLPADAQDRLFAQITELSAPGSRVAAESMGIHAQDRRER----- MLBr_02640|M.leprae_Br4923 AEGLLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQ----- ***** ***. * * ** : ** * :*.* . Mb0150|M.bovis_AF2122/97 ---RWNRMRERLGLDI--DVQALTYHEPDRSDAAQWLATHGWQVHSVSNR Rv0145|M.tuberculosis_H37Rv ---RWNRMRERLGLDI--DVQALTYHEPDRSDAAQWLATHGWQVHSVSNR MMAR_0356|M.marinum_M ---RWNRMRDRLGLDI--NVEALTYREPGRADAAEWLANHGWQVYSVSNR MUL_4763|M.ulcerans_Agy99 ---RWNRMRDRLGLDI--NVEALTYREPGRTDAAEWLANHGWQVYSVSNR MAV_5150|M.avium_104 ---RWLRMRERLGLDV--NVAALTYHEPDRSDAAAWLTGHGWRVHSVDNR MSMEG_0093|M.smegmatis_MC2_155 RRARGEQMRKQLDLDI--DVDALMYTADDRADAAQWLSEHGWQVEAVPSA TH_2759|M.thermoresistible__bu WRDRTARMKAALDLNL--DFEALTYDDPDRADAGEWLAAHGWHPDSVPGT MAB_4607c|M.abscessus_ATCC_199 REQVRAAFKTAIDVDV--TIENLIYEDENRADPAEWLDAHGWSVTKTDAH Mflv_0743|M.gilvum_PYR-GCK MRERFASIASQIDIEP-MDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQ Mvan_0104|M.vanbaalenii_PYR-1 MRERFASITAQFDVEP-MDITELTYEDPDRADVAQWLTAHGWRAEAVPSQ MLBr_02640|M.leprae_Br4923 MQLRFRRVSDALGFEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAP . :..: . * * .*: . ** *** Mb0150|M.bovis_AF2122/97 EEMARLGRA---IPQDLVDETVRTTLLRGRLVTPAQPA Rv0145|M.tuberculosis_H37Rv EEMARLGRA---IPQDLVDETVRTTLLRGRLVTPAQPA MMAR_0356|M.marinum_M EEMARLGRP---VPEDLVDEAITTTLLRASLEISR--- MUL_4763|M.ulcerans_Agy99 EEMARLGRP---VPEDLVDEAITTTLLRASLEILR--- MAV_5150|M.avium_104 DEMARLGRP---VPEDLSDEAVRSTLLRAHLGGSTG-- MSMEG_0093|M.smegmatis_MC2_155 DEMARLGRPA--AEADLAEFGMDGVLMRARLDGERL-- TH_2759|M.thermoresistible__bu EEMARMGRP---VPADLLDVAVPSTLLRAHLNGASR-- MAB_4607c|M.abscessus_ATCC_199 DEMARLGRP---VAEDVERGTFRGQLIQGELR------ Mflv_0743|M.gilvum_PYR-GCK DAMRRLDRY---VEVADSDGQSFSTFTTGTKL------ Mvan_0104|M.vanbaalenii_PYR-1 DEMRRLHRL---VEIADGDDQSFSTFTTAVKR------ MLBr_02640|M.leprae_Br4923 DEMRRVGRWGDGVPMAD-DKDAFAEFVTAHRL------ : * *: * : .