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M. thermoresistible (build 8) TH_4631 (-)

annotation: Alcohol dehydrogenase GroES domain protein
coordinates: 86152 - 86892
length: 247

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4631--100% (247)Alcohol dehydrogenase GroES domain protein
M. thermoresistible (build 8)TH_4578-2e-1429.95% (187) PUTATIVE alcohol dehydrogenase B
M. thermoresistible (build 8)TH_2673-3e-1229.46% (224) PUTATIVE Alcohol dehydrogenase GroES domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1929-1e-1829.22% (219) dehydrogenase
M. gilvum PYR-GCKMflv_0638-6e-2732.77% (235) alcohol dehydrogenase
M. tuberculosis H37RvRv1895-3e-1828.77% (219) dehydrogenase
M. leprae Br4923MLBr_02053-1e-0927.93% (222) putative alcohol dehydrogenase
M. abscessus ATCC 19977MAB_0526c-2e-1626.83% (205) hypothetical protein MAB_0526c
M. marinum MMMAR_2790-3e-1827.78% (234) dehydrogenase
M. avium 104MAV_4173-2e-1827.73% (238) oxidoreductase, zinc-binding dehydrogenase family protein
M. smegmatis MC2 155MSMEG_3605-7e-7861.18% (237) sorbitol dehydrogenase
M. ulcerans Agy99MUL_2962-4e-1726.92% (234) dehydrogenase
M. vanbaalenii PYR-1Mvan_0527-7e-2732.77% (235) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


TH_4631|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3605|M.smegmatis_MC2_155      MNAVAADARGTMRASVLTSVGTVVVE----DRPVPT-PGPHEVLVEVAAV
Mb1929|M.bovis_AF2122/97            --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv         -----------MRAVVIDGAGSVRVN----TQPDPALPGPDGVVVAVTAA
MMAR_2790|M.marinum_M               -----------MRTVVIDGPGSIRVD----NRPDPALPGSDGVIVAVSAA
MUL_2962|M.ulcerans_Agy99           -----------MRTVVIDGPGSIRVD----NRPDPALPGSDGVIVVVSAA
Mflv_0638|M.gilvum_PYR-GCK          -----------MRAAIYHGREDVRIE----ELPDPS-PRAGEVVIEVARA
Mvan_0527|M.vanbaalenii_PYR-1       -----------MRAAIYHGREDVRIE----ELPDPS-PRAGEVVIEVARA
MAV_4173|M.avium_104                ---------------MVTSPDRAEVI----DVERPG-VGPRDVLVRMRAC
MAB_0526c|M.abscessus_ATCC_199      -----------MRASVLRNGSMVYRD----DVPSPT-PGEGQVLVKVSAC
MLBr_02053|M.leprae_Br4923          -----------MHAWRVRRPGPIQTSPLEWVTTEVPCPEPSELLVAVRAC
                                                                                      

TH_4631|M.thermoresistible__bu      ----------------------------------------VN---GXXX-
MSMEG_3605|M.smegmatis_MC2_155      GVCGSDVHYYRHGRIGDFVVNEPMILGHELSGRIAAVGEGVD---PARVG
Mb1929|M.bovis_AF2122/97            --------------------------------------------------
Rv1895|M.tuberculosis_H37Rv         GICGSDLHFYEG---EYPFTEP-VALGHEAVGTIVEAGPQVR---TVGVG
MMAR_2790|M.marinum_M               GICGSDLHFYEG---EYPLAEP-VALGHEAVGTVVEKGPDVH---TVEVG
MUL_2962|M.ulcerans_Agy99           GICGSDLHFYEG---EYPLAEP-VALGHEAVGTVVEKGPDVH---TVEVG
Mflv_0638|M.gilvum_PYR-GCK          GICGTDLHEYIA---GPMHAAPGVVIGHEYSGTVVGVGSGVR---EFTEG
Mvan_0527|M.vanbaalenii_PYR-1       GICGTDLHEYIA---GPMHAAPGVVIGHEYSGTVVGVGSGVR---EFTEG
MAV_4173|M.avium_104                GICGSDAFYISIG--GVPPRQGHTPLGHEPAGEVVEVGAEVT---GLAVG
MAB_0526c|M.abscessus_ATCC_199      GICGSDLHFAKHGARAIELSKQMVGMPSLTDGVDLSTDVFMG---HEFAA
MLBr_02053|M.leprae_Br4923          GVCRTDLHVAEG---DLPVHREHVTPGHEVVGEVLGVGSDVDAAAGFDVG
                                                                                      

TH_4631|M.thermoresistible__bu      ---------------EETRRGRYNLCP-H--MRFYGTPPVDGALCEYVTI
MSMEG_3605|M.smegmatis_MC2_155      QRV-AVEPQHPCRRCKQCKAGRYNLCP-E--IKFYATPPIDGAFCRYVTI
Mb1929|M.bovis_AF2122/97            --------------------------------MIFGAGVLGGAQADLLAV
Rv1895|M.tuberculosis_H37Rv         DLV-MVSSVAGCGVCPGCETHDPVMCFSG--PMIFGAGVLGGAQADLLAV
MMAR_2790|M.marinum_M               DQV-MVSSVAGCGACAGCATRDPAMCVSG--PQIFGSGALGGAQADLLAV
MUL_2962|M.ulcerans_Agy99           DQV-MVSSVAGCGACAGCATRDPAMCVSG--PQIFGSGALGGAQADLLAV
Mflv_0638|M.gilvum_PYR-GCK          DRV-CGVGVFGCGECGFCKQGAEALCG----AVGFIGFAVNGALARYASL
Mvan_0527|M.vanbaalenii_PYR-1       DRV-CGVGVFGCGECGFCKQGAEALCG----AVGFIGFAVNGALARYASL
MAV_4173|M.avium_104                DHV-VINPMAAP-------------------SGIIGNGGASGALADYLLI
MAB_0526c|M.abscessus_ATCC_199      EVI-EAGPRTQAPASGTAVTSIPILLSAKGLEPIVYSNTTLGGYAEQMLL
MLBr_02053|M.leprae_Br4923          DRVGIAWLRYTCGVCNYCRSGTENLCVQS----RYTGWDVDGGYAEFTTV
                                                                             *. .    :

TH_4631|M.thermoresistible__bu      GAA----FAHPVPAEMTDNAAALCEP-LSVAIATVDKAAVAGGSRVLIAG
MSMEG_3605|M.smegmatis_MC2_155      DDD----MAHAVPDSISDDAAALLEP-LSVAIATMRKAGVVPGSSILIAG
Mb1929|M.bovis_AF2122/97            PAADF--QVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIG
Rv1895|M.tuberculosis_H37Rv         PAADF--QVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIG
MMAR_2790|M.marinum_M               PAADF--QVLKIPAAITTEQALLLTDNLATGWAAARRADILFGATVAVIG
MUL_2962|M.ulcerans_Agy99           PATDF--QVLKIPAAITTEQALLLTDNLATGWAAARRADIPFGATVAVIG
Mflv_0638|M.gilvum_PYR-GCK          PTK----ALFRIPDEISLAEAAVVEP-IASAYHAVRRSGLAAGGTVFIAG
Mvan_0527|M.vanbaalenii_PYR-1       PTK----ALFRIPDEISLAEAAVVEP-IASAYHAVRRSGLAAGGTVFIAG
MAV_4173|M.avium_104                ENAVRGTSLEVIPDHIPWEVAALNEP-MAVARHGVNRCQPRPTDKVVVFG
MAB_0526c|M.abscessus_ATCC_199      SAP----LLLPIPNGLDPRHAALTEP-MAVGLHAVNKSAIQPGTGAIVIG
MLBr_02053|M.leprae_Br4923          PAA----FAHHLPSGYSDCELAPLLCAGIIGYRSLLRSELPPGGRLGIYG
                                               :*                 .     :.         : *

TH_4631|M.thermoresistible__bu      AGPIGLMTAQVARAYGATDIVVTDLDPHRRRLAHRFGAT----TTLDPQT
MSMEG_3605|M.smegmatis_MC2_155      AGPIGVICAQTARAFGAARIVVTDLVAERRERVLRFGAT----EVLDPAV
Mb1929|M.bovis_AF2122/97            LGAVGLCALRSAFIHGAATVFAVDRVKGRLQRAATWGAT----PIPSPAA
Rv1895|M.tuberculosis_H37Rv         LGAVGLCALRSAFIHGAATVFAVDRVKGRLQRAATWGAT----PIPSPAA
MMAR_2790|M.marinum_M               LGAVGLCAVRSALAQGAATVFAVDRVQGRLQRASEWGAT----AVASPAA
MUL_2962|M.ulcerans_Agy99           LGAVGLCAVRSALAQGAATVFAVDRVQGRLQRAAEWGAT----AVASPAA
Mflv_0638|M.gilvum_PYR-GCK          AGPIGLALVQFSLAQGATQVIVSEVSATRRVAAHRVGATRVIDPLAEDAV
Mvan_0527|M.vanbaalenii_PYR-1       AGPIGLALVQFSLAQGATQVIVSEVSATRRVAAHRVGATRVIDPLAEDAV
MAV_4173|M.avium_104                AGPIGLGATLAFKSLGVQHIVVIDLIPGRLDKAVRIGADAVVNSAEEDVA
MAB_0526c|M.abscessus_ATCC_199      CGPVGIAVIAALHNLGIEPIVASDYSSARRDLAQRMGAHQVVDPKIEPTF
MLBr_02053|M.leprae_Br4923          FGGSAHIAAQVALVQG-AEVHVMTRGARAQELALELGAAS--AQGVADLP
                                     *  .          *   : .          .   **            

TH_4631|M.thermoresistible__bu      DDVTGLR------------VDAFIDASGAPAAVMSGLAAVRPAGRAVLVG
MSMEG_3605|M.smegmatis_MC2_155      DDVAALDP----------KVDAFVDASGAAPAVVSGIKAVGPAGNVVLVG
Mb1929|M.bovis_AF2122/97            ETILAATRGR--------GADSVIDAVGTDASMSDALNAVRPGGTVSVVG
Rv1895|M.tuberculosis_H37Rv         ETILAATRGR--------GADSVIDAVGTDASMSDALNAVRPGGTVSVVG
MMAR_2790|M.marinum_M               EAIVAATGGR--------GADSVIDAVGTDASMTDALNAVRAGGTVSVVG
MUL_2962|M.ulcerans_Agy99           EAIVAATSGR--------GADSVIDAVDTDASMTDALNAVRAGGTVSVVG
Mflv_0638|M.gilvum_PYR-GCK          EVVRTLTNGN--------GVDISFDAAGVQPALDAALGVLRPRGRLMVVA
Mvan_0527|M.vanbaalenii_PYR-1       EVVRMLTNGN--------GVDISFDAAGVQPALDAALGVLRPRGRLMVVA
MAV_4173|M.avium_104                ARLVELHGPGESMFPGKAGTDIYLDAAGAPAVVSTALAAAKKGATLGIVG
MAB_0526c|M.abscessus_ATCC_199      HAWSRIGAG----------APVIFEAVGVPGILNEVLRDAPRSARVVVVG
MLBr_02053|M.leprae_Br4923          PVP----------------LDAAIVFAPVGDLVLPACEALNRGGTLAIAG
                                                           .    .   :          .   :..

TH_4631|M.thermoresistible__bu      MG--AETMELPVQTIQNRELILTGVFRYANTWPAAIALIRTGRVDVDALI
MSMEG_3605|M.smegmatis_MC2_155      MG--ADDVTLPVGYIQNMEINVTGVFRYTDTWPAAIHLVSSGAVDLDALV
Mb1929|M.bovis_AF2122/97            VHDLQPFPLPALTCLLRSITLRMTMAPVQRTWPELIPLLQSGRLDVDGIF
Rv1895|M.tuberculosis_H37Rv         VHDLQPFPVPALTCLLRSITLRMTMAPVQRTWPELIPLLQSGRLDVDGIF
MMAR_2790|M.marinum_M               VHDLQPFPLPALTCLLRSITLRLTIAPVQRTWSELIPLLESGRLDVDGIF
MUL_2962|M.ulcerans_Agy99           VHDLQPFPLPALTCLLRSITLRLTIAPVQRTWSELIPLLESGRLDVDGIF
Mflv_0638|M.gilvum_PYR-GCK          IWEAPAGIDINRSVMREANIGFSFCYEAQRQVPAILDLLATGAINLGELI
Mvan_0527|M.vanbaalenii_PYR-1       IWEAPAGIDINRSVMREANIGFSFCYEAQRQVPAILDLLATGAINLGELI
MAV_4173|M.avium_104                VH--KEPVPVDLINVMSNEITIVGSMGYPDEIFEVTGDLVRNWEKYALIV
MAB_0526c|M.abscessus_ATCC_199      VCMEPDAITPYFGIAKEVAVQFVLAY-EPAEFSETLRRIAHGEIDVAPLV
MLBr_02053|M.leprae_Br4923          IHLSDIPQLNYQRHLFQERQIRSVTSNTRADARAFLDFAAQHHIAVT---
                                    :                                                 

TH_4631|M.thermoresistible__bu      TGRYPLEKTA-EALESDRIPGNIKSVVEVGTS------------------
MSMEG_3605|M.smegmatis_MC2_155      TGRYDLDHVA-EALDSDSDPASLKSIVVPE--------------------
Mb1929|M.bovis_AF2122/97            TTTLPLDEAA-KGYATARARSGEELKVLLTP-------------------
Rv1895|M.tuberculosis_H37Rv         TTTLPLDEAA-KGYATARARSGEELRFCLRPDSRDVLGAHETVDLYVHVR
MMAR_2790|M.marinum_M               TTSLPLDEAA-KGYSIAGSRSGNDVKVLLKV-------------------
MUL_2962|M.ulcerans_Agy99           TTSLPLDEAA-KGYSIAGSRSGNDVKVLLKV-------------------
Mflv_0638|M.gilvum_PYR-GCK          TDEIPLDAVVSQGLEELRVNRDAHVKILIDPSA-----------------
Mvan_0527|M.vanbaalenii_PYR-1       TDEIPLDAVVSQGLEELRVNRDAHVKILIDPSA-----------------
MAV_4173|M.avium_104                SHTIPFDRVG-EALELARTPGAADKVVVTFC-------------------
MAB_0526c|M.abscessus_ATCC_199      TGEVGLEDVG-SAFADLGDPERHCKILVVP--------------------
MLBr_02053|M.leprae_Br4923          TPEYPLEQAD-QALTDLSVGRISGAAVLLA--------------------
                                    :    :: .  ..             .                       

TH_4631|M.thermoresistible__bu      ------------------------
MSMEG_3605|M.smegmatis_MC2_155      ------------------------
Mb1929|M.bovis_AF2122/97            ------------------------
Rv1895|M.tuberculosis_H37Rv         RCQSVADLQLEGAADGVDGPSMLN
MMAR_2790|M.marinum_M               ------------------------
MUL_2962|M.ulcerans_Agy99           ------------------------
Mflv_0638|M.gilvum_PYR-GCK          ------------------------
Mvan_0527|M.vanbaalenii_PYR-1       ------------------------
MAV_4173|M.avium_104                ------------------------
MAB_0526c|M.abscessus_ATCC_199      ------------------------
MLBr_02053|M.leprae_Br4923          ------------------------