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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4612 | - | - | 100% (351) | putative 2-dehydropantoate 2-reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0533 | - | 2e-06 | 35.71% (84) | ketopantoate reductase ApbA/PanE |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2908c | - | 3e-14 | 27.30% (359) | 2-dehydropantoate 2-reductase |
| M. marinum M | MMAR_0863 | apbA | 1e-12 | 26.22% (328) | ketopantoate reductase, ApbA |
| M. avium 104 | MAV_4625 | panE | 2e-13 | 26.59% (331) | 2-dehydropantoate 2-reductase |
| M. smegmatis MC2 155 | MSMEG_2919 | - | 2e-48 | 37.99% (329) | 2-dehydropantoate 2-reductase |
| M. ulcerans Agy99 | MUL_0617 | apbA | 2e-09 | 25.30% (328) | ketopantoate reductase, ApbA |
| M. vanbaalenii PYR-1 | Mvan_0557 | - | 2e-07 | 26.94% (219) | ketopantoate reductase ApbA/PanE |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0863|M.marinum_M ------MKIAIIGCGAMGSIYAARLAGAGNDVAVIDRHQPNVDQITRTGL
MUL_0617|M.ulcerans_Agy99 ------MKIAIIGCGAMGSIYAARLAGADNDVAVIDRHQPNVDQITRTGL
MAV_4625|M.avium_104 ------MKIAVIGCGAMGSIYAAKLAAAGEQVLAVDRHRPSVERINRDGL
Mflv_0533|M.gilvum_PYR-GCK ------MRVLILGAGGLGSVLGGYLANIGVDVTLVG-RPAHTEAITRYGL
Mvan_0557|M.vanbaalenii_PYR-1 ------MRVLILGAGGLGSVLGGYLANIGVDVTLVG-RPAHAEAITRYGL
TH_4612|M.thermoresistible__bu ---------VIVGSGAIGGTVGGLLARSGADVVLVA-RGAHAQALADRGL
MSMEG_2919|M.smegmatis_MC2_155 MTDTTPHPVVVYGTGAVGGVIAAQLRLGGFDVTAVA-RGDHLRAIRAGGL
MAB_2908c|M.abscessus_ATCC_199 ------MRIAVAGAGSIGCYVGGRLQAAGHQVVYIG-RPSLGRAIAEHGL
: * *.:* .. * . :* : : : **
MMAR_0863|M.marinum_M RVSG-PGTDQLVS----LRAATTAPTEVMDLVVLAVKAADVAAGAR----
MUL_0617|M.ulcerans_Agy99 RVSG-PGTDQLVS----LRAATTAPTEVMDLVVLAVKAADVAAGAR----
MAV_4625|M.avium_104 RVTG-PGCDQVVP----LRASTGAVDETMDLVVLAVKAADVEAAAR----
Mflv_0533|M.gilvum_PYR-GCK RITG-RRGDLVITDNLTAVDQTAKATGHFDYLVLAVKGKDTAQALA----
Mvan_0557|M.vanbaalenii_PYR-1 RITG-RRGDLVITDNLTAVDQTAKATGHFDYLVLAVKGKDTAQALA----
TH_4612|M.thermoresistible__bu TLRT-PDGTFEIG-VTAAADPAEVRLTSRDVLVFATKTQHLEDALHAWVD
MSMEG_2919|M.smegmatis_MC2_155 KLVT-QAGERTVP-LPAAADAGEVDWSDEPVVILAVKSHQTGAAL-----
MAB_2908c|M.abscessus_ATCC_199 SLSDYLGWSAAIPASECAFSEDIDTVRSADIVLVTVKSAATAQMAES---
: : ::.:.*
MMAR_0863|M.marinum_M -------QALCMLGADTPVLTIQNGLGSAETVADIVGEQR---VAVGIAS
MUL_0617|M.ulcerans_Agy99 -------QALCMLGADTPVLTIQNGLGSAETVADIVGEQR---VAVGIAS
MAV_4625|M.avium_104 -------QALPMLGPDTAVLTIQNGLGSAETVAGVVGAQR---VAVGIAS
Mflv_0533|M.gilvum_PYR-GCK -------EADGLRDCVSSALSVQNTVEKDATLAGWLGPDR---VIG-AST
Mvan_0557|M.vanbaalenii_PYR-1 -------EADGLRDCVSSALSVQNTVEKDATLARWLGPDR---VIG-AST
TH_4612|M.thermoresistible__bu RPVHHGDTVVGTAGSTLPVLTALNGVVAEEMALRFFARVFGVCVWMPAAH
MSMEG_2919|M.smegmatis_MC2_155 ------DDLATHAPAHTAIFAAQNGVANEMAILRRFADVYGVTVMLPAAH
MAB_2908c|M.abscessus_ATCC_199 --------LAGRLEPGAVVVSLQNGIRNPAQLSRYIKQHN----VITGIV
.: * : .
MMAR_0863|M.marinum_M GFGAARLAPG--HVHHNAMKAMRFGAYSSLPHETVERIAHAWTEAGFDAA
MUL_0617|M.ulcerans_Agy99 GFGAARLAPGHVHVHHNAMKAMRFGAYSSLPHETVERIAHAWTEVGFDAA
MAV_4625|M.avium_104 GFGASRVAPG--HVHHNAMRAMRFGPYSSLPHARVESIARTWAHAGFDAA
Mflv_0533|M.gilvum_PYR-GCK IEGGTLLEPGLVRNHLTAEVTAYFGELDGTSSARVDDLTAAFTNAGLPAK
Mvan_0557|M.vanbaalenii_PYR-1 IEGGTLLEPGLVRNHLTAEVTAYFGELDGTSSARVDDLTAAFTNAGLPAK
TH_4612|M.thermoresistible__bu VVPGEVIVRSWPVAGQFHISRWPADLADAEDDRLLSDIAATWTPAGLLVA
MSMEG_2919|M.smegmatis_MC2_155 LEPGVVVQQSHPLAGILDLGRYPSG-----ADAVAHDVAAMLRASQFLSE
MAB_2908c|M.abscessus_ATCC_199 GFNVAQVGAAHFHQGTQGKLSLSTG---------AESLAGALTHGGLLTT
: . . :: :
MMAR_0863|M.marinum_M AVTDIAAMQWEKLICNVAYSAP--CALTGMTVGQVLDDAELGP---VSRA
MUL_0617|M.ulcerans_Agy99 AVTDIAAMQWEKLICNVAYSAP--CALTGMTVGQVLDDAEMGP---VSRA
MAV_4625|M.avium_104 AVTDIAAMQWEKLICNVAYSAP--CALTGMTVGQVMDDAEMGP---VSRA
Mflv_0533|M.gilvum_PYR-GCK AVGNIEQVEWEKLAQIALAAAWSVTALGAIPDASVFEGMEVREGAMYFVA
Mvan_0557|M.vanbaalenii_PYR-1 AVGNIEQVEWEKLAQIALAAAWSVTALGAIPDASVFEGMEVREGAMYFVA
TH_4612|M.thermoresistible__bu RPPDVAPWKYRKLLANLANAVVALTGSGRGDPVVIAAAQREGEAVLRHAG
MSMEG_2919|M.smegmatis_MC2_155 VRPDIMAWKHRKLIMNLGNGVTAIFRPGPAADELAAQARAEAEEVLGAAG
MAB_2908c|M.abscessus_ATCC_199 VRDDMAAVQWGKLVVNLNNSVN------ALSGLPLKAELGDRDYRLVLAA
:: : ** .. .
MMAR_0863|M.marinum_M AATEAWAVARASG----------------IAVAVTDPVAHARAFGAAMPN
MUL_0617|M.ulcerans_Agy99 AATEAWAVARASG----------------IAVAVTDPVAHARAFGAAMPN
MAV_4625|M.avium_104 AATEAWSVARASG----------------VAIAVADAVEHVRAFGAQMPD
Mflv_0533|M.gilvum_PYR-GCK LAKDLLGVYRAKGYEPMNFFAPLSRLKELDALPTADAIEFVIGQGRAMRE
Mvan_0557|M.vanbaalenii_PYR-1 LAKDLLGVYRAKGYEPMNFFAPLSRLKELDALPTADAIEFVIGQGRVMRE
TH_4612|M.thermoresistible__bu IEFVPAEVEREARRH-----GPRDRDVADAGDVVANSTWQSLARNSGSVE
MSMEG_2919|M.smegmatis_MC2_155 IPVVPPEQDTERRGR-----FLAGR----VRDDVHGSTWQSVARGHTEVE
MAB_2908c|M.abscessus_ATCC_199 AQREALGLLRRAGQP---VVSPLAAPLSLMPWVLTMPNPIFTRAARQMVA
.
MMAR_0863|M.marinum_M ----AKPSALLDHEARRASEIDVINGAVGRHGARVGVPTP--VNTTLTAL
MUL_0617|M.ulcerans_Agy99 ----AKPSALLDHEARRASEIDVINGAVG-------VPTP--VNTTLTAL
MAV_4625|M.avium_104 ----AKPSALLDHEARRVSEIDVINGAVPRQGARVGVDAP--VNATLTAV
Mflv_0533|M.gilvum_PYR-GCK KGNSGHPSMYEDVLRRRKTEVDFMLAPYLAAAQELGMDTP--TLRVAYQI
Mvan_0557|M.vanbaalenii_PYR-1 KGNLGHPSMYEDVLRRRKTEVDFMLAPYLAAAQELGMDTP--TLRVAYQI
TH_4612|M.thermoresistible__bu TDYLNGEIVRIAHRHGMTAPVNAGLARLARAAARDGHPPGRYSGGELAEA
MSMEG_2919|M.smegmatis_MC2_155 TDYFNGEIALQARLIGRSAPVNEYLQRVTADHARHGRPP---RSLDAAEA
MAB_2908c|M.abscessus_ATCC_199 MDPQARSSMLDDITLGRPTEIDYINGEVVELAKRLGAKAP--VNAALVSL
: :: .
MMAR_0863|M.marinum_M VKSVERQWSAVNSD-------------------
MUL_0617|M.ulcerans_Agy99 VKSVERQWSAVNSD-------------------
MAV_4625|M.avium_104 VKSIERRWR------------------------
Mflv_0533|M.gilvum_PYR-GCK IKTVDRFLA------------------------
Mvan_0557|M.vanbaalenii_PYR-1 IKTVDRFLA------------------------
TH_4612|M.thermoresistible__bu LGLVGEALGADVMVEGR----------------
MSMEG_2919|M.smegmatis_MC2_155 LSHITAGAAAPEHL-------------------
MAB_2908c|M.abscessus_ATCC_199 IRDVTSSHEITRWPGPKLRREINHRAAASHMLS
: :