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M. thermoresistible (build 8) TH_4587 (-)

annotation: putative oleandomycin glycosyltransferase
coordinates: 4405605 - 4406789
length: 395

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4587--100% (395)putative oleandomycin glycosyltransferase
M. thermoresistible (build 8)TH_3465-7e-0826.06% (142) PUTATIVE UDP-glucuronosyl/UDP-glucosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2759c-3e-0528.93% (197) alanine rich transferase
M. gilvum PYR-GCKMflv_2592-1e-1727.17% (427) glycosyl transferase family protein
M. tuberculosis H37RvRv2958c-7e-0822.26% (301) glycosyl transferase
M. leprae Br4923MLBr_02348-1e-0724.59% (427) putative glycosyl transferase
M. abscessus ATCC 19977MAB_4686-1e-0629.36% (109) glycosyltransferase
M. marinum MMMAR_1974-6e-0528.27% (191) glycosyl transferase
M. avium 104MAV_3631-6e-0639.22% (102) hypothetical protein MAV_3631
M. smegmatis MC2 155MSMEG_0730-7e-5438.44% (398) oleandomycin glycosyltransferase
M. ulcerans Agy99MUL_3383-1e-0630.00% (190) glycosyl transferase
M. vanbaalenii PYR-1Mvan_4034-3e-1926.85% (432) glycosyl transferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2592|M.gilvum_PYR-GCK          -----MNAMPDILITACPPVGHIGPLLNVAHGLVAHGHRVTVLTSARHAD
Mvan_4034|M.vanbaalenii_PYR-1       --------MPEILIATCPPVGHLSPLLNVARGLVARGDRVTVLTSARHAD
MMAR_1974|M.marinum_M               ---------MRVAVVAGPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLD
MUL_3383|M.ulcerans_Agy99           ---------MRVAVVAGPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLD
MAV_3631|M.avium_104                ---------MRVAVVAGPDPGHSFPAIALCRRFADAGDTPTLFTGAEWLD
Mb2759c|M.bovis_AF2122/97           ---------MRVAVVAGPDPGHSFPAIALCQRFRAAADTPTLFTGVEWLE
TH_4587|M.thermoresistible__bu      --------VAHIVFAVPVGVGHVNPTLGVAAELIARGHRVSYAATERHAA
MSMEG_0730|M.smegmatis_MC2_155      ---MFPRAGLHICVVAASAPSHMYPHLPVVRELVERGHRVSYVVGAHRAE
MAB_4686|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02348|M.leprae_Br4923          ---------MKFTLAASGSRGDVEPFAALGLELQRRGHEVRIGVPPDMLR
Rv2958c|M.tuberculosis_H37Rv        MEETSVAGDPGPDAGTSTAPNAAPEPVARRQRILFVGEAATLAHVVRPFV
                                                                                      

Mflv_2592|M.gilvum_PYR-GCK          KIRAVGADPRPLPYGADYDDARLDADLPGRAHTSGIARINFDVEHVFVRP
Mvan_4034|M.vanbaalenii_PYR-1       KIRAVGAEPRPLPHAADYDDSTLDADLPGRAATAGLARINFDIESIFVRP
MMAR_1974|M.marinum_M               TARAAGVDAIELAGLVATDEDLDAG-----------ARIHRRAAQMALLN
MUL_3383|M.ulcerans_Agy99           TARAAGVDAIELAGLVATDEDLDAG-----------ARIHRRAAQMALLN
MAV_3631|M.avium_104                TARGAGVDAVELDGLAATDEDVDAG-----------ARIHRRAARMAVLN
Mb2759c|M.bovis_AF2122/97           AARAAGIDAVELDGLAATDRDLDAG-----------ARIHRRAAQMAVLN
TH_4587|M.thermoresistible__bu      RIADVGARLVPYATTLSGPEPPPQ----------FTARDFHRATEAALRE
MSMEG_0730|M.smegmatis_MC2_155      LVRDTGADVIGCTSVLPGAPGGPES--------WDDDGDPVRGMQLFLDE
MAB_4686|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02348|M.leprae_Br4923          FVESAGLAAVAYGPDTQEFLARDTYSQWRQWWKILPPIKALQQLRQAWAD
Rv2958c|M.tuberculosis_H37Rv        LARSLDPSRYEVHFACDPRFNKLLGPLPFPHHPIHTVPSEEVLLKIAQGR
                                                                                      

Mflv_2592|M.gilvum_PYR-GCK          MPYQFSAVQELLAAN-SFDAVITDAFFLGVIPLLLDPTLARPPIMAYSTT
Mvan_4034|M.vanbaalenii_PYR-1       LPHQFSALQELLVTD-RFDAVIADALFLGTLPLLLGDPAKRPPILSYSTT
MMAR_1974|M.marinum_M               APALSDLAPDLVVSD-VITACG------GMAAERLG-----IPWIELNPH
MUL_3383|M.ulcerans_Agy99           APALSDLAPDLVVSD-VITACG------GMAAERLG-----IPWIELNPH
MAV_3631|M.avium_104                VPALRDLAPDLVVSD-VITAGG------GMAAELLG-----IPWIELSPH
Mb2759c|M.bovis_AF2122/97           VPRLRALEPELVVSD-VITACG------GMAAELLG-----IPWVELNPH
TH_4587|M.thermoresistible__bu      TGHVLPQVLDGFAGD-RPDLVLH-----DATMAWWG---------RLAAA
MSMEG_0730|M.smegmatis_MC2_155      AIHVLPQLHAALDDD-RPDLVLY-----DIG-GMAG---------PVAAD
MAB_4686|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02348|M.leprae_Br4923          MATDLKSLADGADLV-MTGVVYQG--VVANVAEYYG-----IPFGVLHFV
Rv2958c|M.tuberculosis_H37Rv        LFYNTRTLRKYIAADRKILNEIAPDVVVGDNRLSLSVSARLAGIPYIAIA
                                                                                      

Mflv_2592|M.gilvum_PYR-GCK          PLFLSSRDTAPAGPGILPMPGAVGRLRNRLLGLLSRAVLLRPAHRSAERM
Mvan_4034|M.vanbaalenii_PYR-1       PLFLTSRDTAPAGPGIAPMPGMIGRLRNRVLARATQSVLLRPGQRAADRM
MMAR_1974|M.marinum_M               PLYRPSKGLPPIGSGLAPGTGIRGRLRDTTMRALT-ARSWRAGLRQRAAV
MUL_3383|M.ulcerans_Agy99           PLYRPSKGLPPIGSGLAPGTGIRGRLRDTTMRALT-ARSWRAGLRQRAAV
MAV_3631|M.avium_104                PLYLPSKGLPPIGSGLATGTGLRGRLRDATMRALT-ARSWRAGLRQRAAA
Mb2759c|M.bovis_AF2122/97           PLYLPSKGLPPIGSGLAAGTGIRGRLRDATMRALT-GRSWRAGLRQRAAV
TH_4587|M.thermoresistible__bu      AWEVPVVAGWPNLVGNRHWSMNRYIKVNPLHPRLLWNLWR---AHRLARR
MSMEG_0730|M.smegmatis_MC2_155      QWGVPAAQLSPSEVAWDGYHEDMAEVLGPLLNSPSGQAYRRTFDDWLARS
MAB_4686|M.abscessus_ATCC_1997      ---------MPRPAGWRPGLEICG--------------------------
MLBr_02348|M.leprae_Br4923          PARVNGKIIPSLPSPLNRAILATVWRAHWLLAKKPEDAQRRELGLPKATS
Rv2958c|M.tuberculosis_H37Rv        NAYWSPQARRRFPLPDVPWTRFFGVRPVSILYRLYRPLIFALYCLPLNWL
                                                                                      

Mflv_2592|M.gilvum_PYR-GCK          LRAMGLPDLPVFVLECAILADRVIVPTVPDFEYPRRDLPAHVRFVGAVSP
Mvan_4034|M.vanbaalenii_PYR-1       LEAMGLPELPVFILDSAVLADRVIVPTVPEFEYRRSDLPSHVRFVGPVSP
MMAR_1974|M.marinum_M               RAEIGLAEH-------DPGPLRRLIATLPALEVPRPDWPAEAIVVGPLHF
MUL_3383|M.ulcerans_Agy99           RAEIGLAEH-------DPGPLRRLIATLPALEVPRPDWPAEAIVVGPLHF
MAV_3631|M.avium_104                RAEIGLPAR-------DPGPLRRLIATLPALEVPRPDWPDEAVLVGPLHF
Mb2759c|M.bovis_AF2122/97           RVEIGLPAR-------DPGPLRRLIATLPALEVPRPDWPAEAVVVGPLHF
TH_4587|M.thermoresistible__bu      HGLTGLSLV-----RAT-AADAQLVYLPREFQYAGDTFGAHYAFVGPCLV
MSMEG_0730|M.smegmatis_MC2_155      H--TSLTFD-----EVTGAPHRCLVLIPRVMQRHADRVGDRYRFVGPCID
MAB_4686|M.abscessus_ATCC_1997      ----------------------------YWWPQTDPQWRPDAALVDFLRA
MLBr_02348|M.leprae_Br4923          LSTRRIVKRG------ALEIQAYDELCFPGLAAEWAEYGDRRPFVGALTL
Rv2958c|M.tuberculosis_H37Rv        RRKHGLSSLGWDLCRIFTDGDYTLYADVPELVPTYN-LPANHRYLGPVLW
                                                                                :.    

Mflv_2592|M.gilvum_PYR-GCK          LPGDDFIAPAWWGELYRGRPVVHVTQGTVDNADLTRLIEPTIEALAGEDV
Mvan_4034|M.vanbaalenii_PYR-1       LPGSDFVAPPWWGELNAGRPVVHVTQGTIDNADLTRLIEPTIEALADEDV
MMAR_1974|M.marinum_M               EPTDQLLKVPAGSGPVLVIAPSTALSGTAGLAEVALESLIPGDTLPSGSR
MUL_3383|M.ulcerans_Agy99           EPTDQLLKVPAGSGPVLVIAPSTALSGTAGLAEVALESLIPGGTLSSGSR
MAV_3631|M.avium_104                EPTDRVLDIPAGSGPVVVVAPSTAQTGARGLAEVALSCLTPGETLPAGAR
Mb2759c|M.bovis_AF2122/97           EPTDRVLAIPAGTGPVVVVAPSTALTGTAGLTEVALQSLTPGETVPSGSR
TH_4587|M.thermoresistible__bu      DRPSD-GEWRPPPGRDGRRVVLIALG--TAYHDRADFFRTCLAAFADSGW
MSMEG_0730|M.smegmatis_MC2_155      PRREDPGDWTPPAG-DGP-LALLAFG--TSYTDRADVYRHVITALDGLGW
MAB_4686|M.abscessus_ATCC_1997      GPPPVYVGFG---------------STMTSAKQSEHISQLVRSALRRAGV
MLBr_02348|M.leprae_Br4923          ELPTAADNEVLSWIAAGTPPIYFGFGSMPIVSPTDTVAMIAAACADLGER
Rv2958c|M.tuberculosis_H37Rv        S--PDVKPPTWWHSLPTDRPIIYATLGSSGGKN---LLQVVLNALADLPV
                                                                                      

Mflv_2592|M.gilvum_PYR-GCK          TVVVSTGGRPVSQIRTPLPANTFVAEFLPHDVLLPLVDVLVTNGGYGAVQ
Mvan_4034|M.vanbaalenii_PYR-1       TVVATTGGRPISQIRIPLPANTFVAKYVPHDVLLPMVDVMVTNGGYGAVQ
MMAR_1974|M.marinum_M               LVVSRLGGDDLVTPSWAAVG------LGSQAELLTHADVVICGGGHGMVS
MUL_3383|M.ulcerans_Agy99           LVVSRLGGDDLVTPSWAAVG------LGSQAELLTHADVVICGGGHGMVS
MAV_3631|M.avium_104                LVVSRLAGPELAAPPWAVVG------LGSQAELLRHADVVVCGGGHGMVA
Mb2759c|M.bovis_AF2122/97           LVVSRLSGADLTVPPWAVAG------LGSQAELLTRADLVICGGGHGMVA
TH_4587|M.thermoresistible__bu      HVVLAVGDRVDPAGLGPVPPHVEVHASVPQLQVLRHASVFVSHAGMGSVM
MSMEG_0730|M.smegmatis_MC2_155      RLVLATG-RGELGGLGTVPDWVQLRDTVPQPAVLRVADAFFTHAGMGSCT
MAB_4686|M.abscessus_ATCC_1997      RGIVQAGWAGIDVGDETTLTVT----EVPHRWLFPHVAAVVHHCGAGTTA
MLBr_02348|M.leprae_Br4923          ALISVKPKDLTQVPKFDHVKIVT---SVSHAAVFPACRAVVHHGGAGTTA
Rv2958c|M.tuberculosis_H37Rv        TVIAATAGRNHLKN---VPANAFVADYLPGEAAAARSAVVLCNGGSPTTQ
                                      :                         .          ..   *     

Mflv_2592|M.gilvum_PYR-GCK          RALAEGVPLVVAGDTEDKPEVAARVEYFGVGVNLRTG-TPAPQDLRDAVN
Mvan_4034|M.vanbaalenii_PYR-1       RALSDGVPVVVAGHTEDKPEVAARVRHFGVGIDLRTG-TPTPTQVRRAVR
MMAR_1974|M.marinum_M               KTLLAGVPLVVVPGGGDQWEIANRVVRQGSARLIRP---LGAEALAAAVN
MUL_3383|M.ulcerans_Agy99           KTLLAGVPLVVVPGGGDQWEIANRVVRQGSARLIRP---LGADALAAAVN
MAV_3631|M.avium_104                KTLLAGVPLVAVPGGGDQWEIANRVVRQGSARLIRP---LSADALVAAVN
Mb2759c|M.bovis_AF2122/97           KTLLAGVPMVVVPGGGDQWEIANRVVRQGSAVLIRP---LTADALVAAVN
TH_4587|M.thermoresistible__bu      EALAHRVPIVAVPQMTEQQANADRIAELNLGVRLGRD-EITADRLRSAVE
MSMEG_0730|M.smegmatis_MC2_155      EGLWYGVPMVAMPQAVDQPDNAARLQGIGAGVHLQAH-LPEPAEIRQALL
MAB_4686|M.abscessus_ATCC_1997      AGLRAGVPTVAVPGLGDQPFWARRLRDLGLSADTVPQRTLTVERLAAAIR
MLBr_02348|M.leprae_Br4923          ASLRAGVPTLILWIFIEQPVWAAQIKRLKVGAGRRFS--ATTQRSLAADL
Rv2958c|M.tuberculosis_H37Rv        QALAAGVPVIGLPSNMDQHLNMEALERAGAGVLLRTER-LNTEGVAAAVK
                                      *   ** :      ::      :     .                *  

Mflv_2592|M.gilvum_PYR-GCK          AVLSDAGYRTRAGRLQAAYASRDSVTAIAALLDEVIPEQAAAR------
Mvan_4034|M.vanbaalenii_PYR-1       KVLHEPGFRTKAGWLRSAYAAYDSVAEIAKLVDEAVAQRTQPLQSA---
MMAR_1974|M.marinum_M               EVLSSPGYREAAQRAAASIAD---VADPVQVCHEALALAG---------
MUL_3383|M.ulcerans_Agy99           EVLSSPGYREAAQRAAASIAD---VADPVQVCHEALALAG---------
MAV_3631|M.avium_104                EVLSSPGYRAAAQRAAAGIAD---VADPVRVCREALAG-----------
Mb2759c|M.bovis_AF2122/97           EVLSSPRFREAARRAAASVAG---AADPVRVCHDALALAG---------
TH_4587|M.thermoresistible__bu      RVAGSATIAAAVRTMHDAITAAGGAAAAADIVEDVLTRSR---------
MSMEG_0730|M.smegmatis_MC2_155      YVTSDPRVRLRLNGIREEIRAHGGPAHAADAVEDVAAGRW---------
MAB_4686|M.abscessus_ATCC_1997      TAVTDPGIKIRARRISDLLAAEDGAAHVVSSVNRLLG------------
MLBr_02348|M.leprae_Br4923          RTILAPQYATRAREVANRMSKPDESVNAAADLLEDKASRNKSRTRYQDC
Rv2958c|M.tuberculosis_H37Rv        QVLSGAEFRQAARRLAEAFGP--DFAGFPQHIESALRLVC---------
                                     .   .                   .