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M. thermoresistible (build 8) TH_3465 (-)

annotation: UDP-glucuronosyl/UDP-glucosyltransferase
coordinates: 932272 - 933726
length: 485

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3465--100% (485)UDP-glucuronosyl/UDP-glucosyltransferase
M. thermoresistible (build 8)TH_4587-9e-0826.06% (142) PUTATIVE putative oleandomycin glycosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2986c-3e-1736.61% (183) glycosyl transferase
M. gilvum PYR-GCKMflv_1849-1e-14461.07% (411) UDP-glucuronosyl/UDP-glucosyltransferase
M. tuberculosis H37RvRv2962c-3e-1736.61% (183) glycosyl transferase
M. leprae Br4923MLBr_00128-7e-2038.25% (183) putative glycosyl transferase
M. abscessus ATCC 19977MAB_3062c-6e-1023.59% (407) hypothetical protein MAB_3062c
M. marinum MMMAR_1755-1e-1530.87% (230) glycosyl transferase
M. avium 104MAV_3631-6e-1026.54% (422) hypothetical protein MAV_3631
M. smegmatis MC2 155MSMEG_4670-4e-8042.13% (432) N-glycosylation
M. ulcerans Agy99MUL_3383-2e-1025.49% (412) glycosyl transferase
M. vanbaalenii PYR-1Mvan_4886-1e-14360.00% (410) UDP-glucuronosyl/UDP-glucosyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1849|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4886|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3465|M.thermoresistible__bu      ------------------VGGYGLTRTRLLGRRLSSGSEDEFLARYLLAA
MSMEG_4670|M.smegmatis_MC2_155      ------------------------------------------MADILIAS
MAV_3631|M.avium_104                -------------------------------------------MRVAVVA
MUL_3383|M.ulcerans_Agy99           -------------------------------------------MRVAVVA
MAB_3062c|M.abscessus_ATCC_199      -------------------------------------------MRVAVVA
Mb2986c|M.bovis_AF2122/97           MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAE
Rv2962c|M.tuberculosis_H37Rv        MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAE
MMAR_1755|M.marinum_M               -------------------------MSIATN---AP-QPVRRQRVLFVAE
MLBr_00128|M.leprae_Br4923          ---------------------MGKDAGMSTAPDTVPECQSRRMRILFIAE
                                                                                      

Mflv_1849|M.gilvum_PYR-GCK          -------MPMVDVGAGLQSLGHEVTILTAAEYADLVEAAGLQMLCLPGSV
Mvan_4886|M.vanbaalenii_PYR-1       -------MPMVNVGIGLQALGHDICVLTGAEFSDAVHAAGLQMIPLPDSV
TH_3465|M.thermoresistible__bu      TPLSGHVAPLVQIGATLRSRGHTVTVLTTTEFADAVTRAGLRFTALPAGT
MSMEG_4670|M.smegmatis_MC2_155      HSPIGHIGPLLNVAYGLVGRGDRVTVLTSAQHTDAIRASGAAPVALPDAG
MAV_3631|M.avium_104                GPDPGHSFPAIALCRRFADAGDTPTLFTGAEWLDTARGAGVDAVELDGLA
MUL_3383|M.ulcerans_Agy99           GPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLDTARAAGVDAIELAGLV
MAB_3062c|M.abscessus_ATCC_199      GPDPGHAFPALALCLKFAAAGDDPVLLTGTRWLDQARAAGVESVELLGLQ
Mb2986c|M.bovis_AF2122/97           AVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIP
Rv2962c|M.tuberculosis_H37Rv        AVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIP
MMAR_1755|M.marinum_M               ATTLAHVVRPFVVALSLDPSRYEVHFACDPRFNKLLGPIPFPHHPIYTIP
MLBr_00128|M.leprae_Br4923          AVTLSTVVRPFAVARLLDPSRYEVHFACDPRYNNLLGPLPFPHHPIHTVP
                                              . :   :        .    .  .           :    

Mflv_1849|M.gilvum_PYR-GCK          VIDPPAAAPVVM-RRMPPAVRRFWLGRAELDAIFAKPLAAEAESLTSALA
Mvan_4886|M.vanbaalenii_PYR-1       RIDPPAAAPALL-RKLPVAVRRFWLGRAELASVFAEPLAAEAQSLRAVLR
TH_3465|M.thermoresistible__bu      AIDPPAAPPWWA-RYLPSQARRFLLGRAELDSVYIRPLGHQAAALRSVLD
MSMEG_4670|M.smegmatis_MC2_155      --DPDADRLDIE-NPKRARTSGIARINVDIVAFFVAPMAHQADALAKLLA
MAV_3631|M.avium_104                A--TDEDVDAGA-RIHRRAARMAVLNVPALRDLAPDLVVSDVITAGGGMA
MUL_3383|M.ulcerans_Agy99           A--TDEDLDAGA-RIHRRAAQMALLNAPALSDLAPDLVVSDVITACGGMA
MAB_3062c|M.abscessus_ATCC_199      PRVDDDDADSGA-KIHQRAAHMALANLDQLRALAPDLIVSDVITACGGMA
Mb2986c|M.bovis_AF2122/97           SERFFGNLTQGR-FYAMRTLRKYVEADLRVLDEIAPDLVVGDLRISLSVS
Rv2962c|M.tuberculosis_H37Rv        SERFFGNLTQGR-FYAMRTLRKYVEADLRVLDEIAPDLVVGDLRISLSVS
MMAR_1755|M.marinum_M               SERFLGNLVQGR-FYTTRTLRQYVEEDSRVLAEVAPDLVVGDLRISLSAS
MLBr_00128|M.leprae_Br4923          SEWVLTRIAQGRLFYTTRTLRKYVEEDSKLLSEIEPDLVVGDARWSLSVS
                                                                 :       :            

Mflv_1849|M.gilvum_PYR-GCK          ATTYDAVVADVTFTGVLPMLLRDDA-RPPVVVCGVGPLTISSTDTPPFGM
Mvan_4886|M.vanbaalenii_PYR-1       NGSVDAIVADVAFTGVLPVLLQDSP-RPPVVVCGVGPLTISSRDTPPFGV
TH_3465|M.thermoresistible__bu      REPADAVLVDMTFTGAAALLLDDRP-RPPLLVCSVGPLTLSSADTPPFGM
MSMEG_4670|M.smegmatis_MC2_155      QHRFDAVIADYGFFGILPFLLGNRADRPPFLTYSTTPLMLSSRDTAPAGL
MAV_3631|M.avium_104                AELLG----------------------IPWIELSPHPLYLPSKGLPPIGS
MUL_3383|M.ulcerans_Agy99           AERLG----------------------IPWIELNPHPLYRPSKGLPPIGS
MAB_3062c|M.abscessus_ATCC_199      GELLG----------------------VPWVELNPHPLYLPSKGLPPLGS
Mb2986c|M.bovis_AF2122/97           ARLAG----------------------IPYIAIANAYWSPYAQRRFPLPD
Rv2962c|M.tuberculosis_H37Rv        ARLAG----------------------IPYIAIANAYWSPYAQRRFPLPD
MMAR_1755|M.marinum_M               ARLAG----------------------IPYVAIANAYWSPYSRRRFPLPE
MLBr_00128|M.leprae_Br4923          ARLAS----------------------IPYIAIANAYWSSHARRRLPLPD
                                        .                       * :          :    *   

Mflv_1849|M.gilvum_PYR-GCK          AWQPE----AGVDYTQMTA-VAHRVIMRASQRRFDRALRRAGCGRSPVFI
Mvan_4886|M.vanbaalenii_PYR-1       AWQPE----RGLDYRRMTT-AAHRVIMRSSQRRFNHALRQAGSDACPLFV
TH_3465|M.thermoresistible__bu      AWQPR----PGVDYRGMTA-VAHRVIMAGSRRRFDRALRTAGAGPAPVFL
MSMEG_4670|M.smegmatis_MC2_155      GLPPPRHAVERLRNRALET-LTHKVLLRASQRAVQEQLHRMNCRPLPVFL
MAV_3631|M.avium_104                GLATG----TGLRGR-----LRDATMRALTARSWRAGLRQRAAARAEIGL
MUL_3383|M.ulcerans_Agy99           GLAPG----TGIRGR-----LRDTTMRALTARSWRAGLRQRAAVRAEIGL
MAB_3062c|M.abscessus_ATCC_199      GLAPG----VGLRGR-----LRDGLMRRLTQKSIDQGLRQRSQARVEIGL
Mb2986c|M.bovis_AF2122/97           VIWTR---LFGVRLVKLLYRLERPLLFALQCMPLNWVRRRHGLSSLGWNL
Rv2962c|M.tuberculosis_H37Rv        VIWTR---LFGVRLVKLLYRLERPLLFALQCMPLNWVRRRHGLSSLGWNL
MMAR_1755|M.marinum_M               VFWSR---LFGVRLVKRAYRLERPLFFALQCMPLNRVRRKHGLPSLGLNL
MLBr_00128|M.leprae_Br4923          VLWTR---ILGVRLVNILFRLYSPLIFAIYCLPLNWVRRKHGLPSLGSNI
                                       .       :             :            :          :

Mflv_1849|M.gilvum_PYR-GCK          SDWPRLADGILQLSVRDFEYPRSDLPATVEYVGPVLPDGTAGFVPPPWWR
Mvan_4886|M.vanbaalenii_PYR-1       SDWPRLADGLLQLSVQALEYPRGDLPATVEFVGPVLPAGPEDFDPPHWWG
TH_3465|M.thermoresistible__bu      SDWPALADRLIQLGVPGFEYHRGDLPSTVDFAGPVLPTGLDGVTLPAWWD
MSMEG_4670|M.smegmatis_MC2_155      FDGAVLSERVIAPTVPQFDYHRSDLPKNVRYVGAVHPMPNQGFRRPMWWR
MAV_3631|M.avium_104                PARDPGPLRRLIATLPALEVPRPDWPDEAVLVGPLHFEPTDRVLD-----
MUL_3383|M.ulcerans_Agy99           AEHDPGPLRRLIATLPALEVPRPDWPAEAIVVGPLHFEPTDQLLK-----
MAB_3062c|M.abscessus_ATCC_199      PARDPGPMRRLIATLPALEVPRPDWPAEAVVVGPLHWEPTDVVLQ-----
Mb2986c|M.bovis_AF2122/97           CRIFTDGDHTLYADVPELMP-TYDLPANHEYLGPVLWSPAGKPPT-----
Rv2962c|M.tuberculosis_H37Rv        CRIFTDGDHTLYADVPELMP-TYDLPANHEYLGPVLWSPAGKPPT-----
MMAR_1755|M.marinum_M               CRIFTDGDQTLYADIPELQP-TYNRPDNHQYLGPVLWSPSGETPD-----
MLBr_00128|M.leprae_Br4923          GCIYTDGDYTLYADVPELVP-TYDLPANHQYLGPVLWSPAGELPR-----
                                              :   :  :     : *      *.:               

Mflv_1849|M.gilvum_PYR-GCK          EIERDGTTVVHVTQGTFDNTDLNQLIGPTFEALEDLDDVLVVATTGGRAG
Mvan_4886|M.vanbaalenii_PYR-1       DVMNAG-AVVHVTQGTFDNADLDQLIAPTLEALGDRADLLVVATTGGRQG
TH_3465|M.thermoresistible__bu      DIRSAA-TVVHVTQGTFDNTDLDQLVVPTLEALTDRPDVLVVATTGGRPG
MSMEG_4670|M.smegmatis_MC2_155      LLDGDR-PVVHVTQGTVDNTDLTRLLEPTLEALAD-EDVVVIASTGGRDL
MAV_3631|M.avium_104                --IPAGSGPVVVVAPSTAQTGARGLAEVALSCLTPGETLPAGARLVVSRL
MUL_3383|M.ulcerans_Agy99           --VPAGSGPVLVIAPSTALSGTAGLAEVALESLIPGGTLSSGSRLVVSRL
MAB_3062c|M.abscessus_ATCC_199      --PPSGSGPVVVIAPSTAFTGAEGMTELAVQALES-----AGARVVISAL
Mb2986c|M.bovis_AF2122/97           -WWDSLPTDRPIVYATLGTSGGRNLLQLVLNALAELPVTVIAATAGRSDL
Rv2962c|M.tuberculosis_H37Rv        -WWDSLPTDRPIVYATLGTSGGRNLLQLVLNALAELPVTVIAATAGRSDL
MMAR_1755|M.marinum_M               -WWDSLPADRPIVYATLGTSGGRNLLQVVLNGLADLPVTVIAATADRSDL
MLBr_00128|M.leprae_Br4923          -WWDSLPTDRPIVYATLGTSGGKNLLQVVLDALADLPVTVIAATAGRSEL
                                               :   :   :.   :   ... *         :       

Mflv_1849|M.gilvum_PYR-GCK          QRIADRIPSNVLVAEWIPYSALLPNVDVMITNGGYGGVQYALGHGVPLIV
Mvan_4886|M.vanbaalenii_PYR-1       QRIHGRIPANARIADWIPYSALLPHVDVMITNGGYGGVQHALAHGVPLVV
TH_3465|M.thermoresistible__bu      QRSGFRVPGNARVTGWLPYRMLMPHVDVMITNGGYGGVQYALSHGVPLIV
MSMEG_4670|M.smegmatis_MC2_155      DVLRTPVPANTYVAKYIPHDLLMPKVDVLVTNGGYGTVQRALSCGVPLVV
MAV_3631|M.avium_104                AGPELAAPP-WAVVGLGSQAELLRHADVVVCGGGHGMVAKTLLAGVPLVA
MUL_3383|M.ulcerans_Agy99           GGDDLVTPS-WAAVGLGSQAELLTHADVVICGGGHGMVSKTLLAGVPLVV
MAB_3062c|M.abscessus_ATCC_199      EPPSSGLPS-WAIAGLARQDLLLSGADLAVCGGGHGFLSKALLAGVPTVV
Mb2986c|M.bovis_AF2122/97           KT----VPANAFVADYLPGEAAAARSAVVVCNGGSLTTQQALVAGVPVIG
Rv2962c|M.tuberculosis_H37Rv        KT----VPANAFVADYLPGEAAAARSAVVVCNGGSLTTQQALVAGVPVIG
MMAR_1755|M.marinum_M               DD----IPANAYVADYLPGEAAAARSDVVICNGGSLTTQQALVAGVPVLG
MLBr_00128|M.leprae_Br4923          QN----VPANAFVADYLPGEAAAARSAVVICNGGSLTTQQAFVAGVPVVG
                                           *     .             : : .**      ::  *** : 

Mflv_1849|M.gilvum_PYR-GCK          AGETSDKAEVAARVAYTGVGIDLGTSSPSAAAIRAAVDAVRRDDRYREAA
Mvan_4886|M.vanbaalenii_PYR-1       AGETSDKAEVAARVDYSGVGIDLKTATPTPEAIRAAVDHVRRDGRYRSAA
TH_3465|M.thermoresistible__bu      AGETSDKAEIAARVEFCGAGIDLGTATPTVRALRAGFDRIRDQDRYRTAA
MSMEG_4670|M.smegmatis_MC2_155      AGKTEDKPEVAARVAWSGAGIDLRTGTPTPAAIRDAVREVLTDKRYLSRA
MAV_3631|M.avium_104                VPGGGDQWEIANRVVRQGSARLIRPLS--ADALVAAVNEVLSSPGYRAAA
MUL_3383|M.ulcerans_Agy99           VPGGGDQWEIANRVVRQGSARLIRPLG--ADALAAAVNEVLSSPGYREAA
MAB_3062c|M.abscessus_ATCC_199      VPGGGDQWELANRVVRQGSAELVRPLS--RDSLASAIGRVLGEPRYREAA
Mb2986c|M.bovis_AF2122/97           VAGNLDQHLNMEAVERAGAGVLLRTERLKSQRVAGAVMQVISRSEYRQAA
Rv2962c|M.tuberculosis_H37Rv        VAGNLDQHLNMEAVERAGAGVLLRTERLKSQRVAGAVMQVISRSEYRQAA
MMAR_1755|M.marinum_M               IASNLDQHLNMQAIEAAGAGLLLRTERLKARSVSAAVCQLLDRPGYRQSA
MLBr_00128|M.leprae_Br4923          IAGNLDQHLNMEAVEAAGAGILLRSERLKVRRVADAVNRVLGQSEYRQAA
                                         *:      :   * .  : .       :  ..  :     *   *

Mflv_1849|M.gilvum_PYR-GCK          GKLRTVIEA-STPIDAIASVLKRCADA-----------------------
Mvan_4886|M.vanbaalenii_PYR-1       ERLRSAIEA-STPVDAIANAIKRLCNA-----------------------
TH_3465|M.thermoresistible__bu      RRLAREIRS-AAPLDSIAATLERIVAADALNRSARTGSAGAPDPDSTDDR
MSMEG_4670|M.smegmatis_MC2_155      RTLEAAFAQ-RDGVAEIIALVDEVIAERRAEVGGELACEVTHEQR-----
MAV_3631|M.avium_104                QRAAAGIAD-VADPVRVCREALAG--------------------------
MUL_3383|M.ulcerans_Agy99           QRAAASIAD-VADPVQVCHEALALAG------------------------
MAB_3062c|M.abscessus_ATCC_199      RRAAAGAIA-VEDPVRVCQDVLAALR------------------------
Mb2986c|M.bovis_AF2122/97           ARLADAFGRDRVGFPQHVENALRLMPENRPRTWLAS--------------
Rv2962c|M.tuberculosis_H37Rv        ARLADAFGRDRVGFPQHVENALRLMPENRPRTWLAS--------------
MMAR_1755|M.marinum_M               EELAEVFGRELARFPQHVESALRRVSEGAVAKSAAG--------------
MLBr_00128|M.leprae_Br4923          QRLAEVLERHVAGLPQHMENVLHTVSQNPPPTSLARQNETTT--------
                                                                                      

Mflv_1849|M.gilvum_PYR-GCK          -----------
Mvan_4886|M.vanbaalenii_PYR-1       -----------
TH_3465|M.thermoresistible__bu      PAPRPARPRVH
MSMEG_4670|M.smegmatis_MC2_155      -----------
MAV_3631|M.avium_104                -----------
MUL_3383|M.ulcerans_Agy99           -----------
MAB_3062c|M.abscessus_ATCC_199      -----------
Mb2986c|M.bovis_AF2122/97           -----------
Rv2962c|M.tuberculosis_H37Rv        -----------
MMAR_1755|M.marinum_M               -----------
MLBr_00128|M.leprae_Br4923          -----------