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FPRAGLHICVVAASAPSHMYPHLPVVRELVERGHRVSYVVGAHRAELVRDTGADVIGCTSVLPGAPGGPE SWDDDGDPVRGMQLFLDEAIHVLPQLHAALDDDRPDLVLYDIGGMAGPVAADQWGVPAAQLSPSEVAWDG YHEDMAEVLGPLLNSPSGQAYRRTFDDWLARSHTSLTFDEVTGAPHRCLVLIPRVMQRHADRVGDRYRFV GPCIDPRREDPGDWTPPAGDGPLALLAFGTSYTDRADVYRHVITALDGLGWRLVLATGRGELGGLGTVPD WVQLRDTVPQPAVLRVADAFFTHAGMGSCTEGLWYGVPMVAMPQAVDQPDNAARLQGIGAGVHLQAHLPE PAEIRQALLYVTSDPRVRLRLNGIREEIRAHGGPAHAADAVEDVAAGRW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0730 | - | - | 100% (400) | oleandomycin glycosyltransferase |
| M. smegmatis MC2 155 | MSMEG_4670 | - | 1e-14 | 25.06% (435) | N-glycosylation |
| M. smegmatis MC2 155 | MSMEG_2342 | - | 1e-10 | 25.18% (417) | putative glycosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2759c | - | 5e-08 | 24.57% (411) | alanine rich transferase |
| M. gilvum PYR-GCK | Mflv_2592 | - | 1e-11 | 28.93% (197) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv2739c | - | 5e-08 | 24.57% (411) | alanine rich transferase |
| M. leprae Br4923 | MLBr_00985 | - | 4e-11 | 24.93% (357) | putative glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_3062c | - | 8e-13 | 23.77% (387) | hypothetical protein MAB_3062c |
| M. marinum M | MMAR_1974 | - | 9e-10 | 26.15% (413) | glycosyl transferase |
| M. avium 104 | MAV_3631 | - | 5e-10 | 26.21% (412) | hypothetical protein MAV_3631 |
| M. thermoresistible (build 8) | TH_4587 | - | 5e-54 | 38.44% (398) | PUTATIVE putative oleandomycin glycosyltransferase |
| M. ulcerans Agy99 | MUL_3383 | - | 1e-09 | 25.14% (354) | glycosyl transferase |
| M. vanbaalenii PYR-1 | Mvan_4034 | - | 3e-16 | 23.79% (433) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1974|M.marinum_M ------MRVAVVAGPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLDTAR
MUL_3383|M.ulcerans_Agy99 ------MRVAVVAGPDPGHSFPAIALCRRFLAAGDIPTLLTGVEWLDTAR
MAV_3631|M.avium_104 ------MRVAVVAGPDPGHSFPAIALCRRFADAGDTPTLFTGAEWLDTAR
Mb2759c|M.bovis_AF2122/97 ------MRVAVVAGPDPGHSFPAIALCQRFRAAADTPTLFTGVEWLEAAR
Rv2739c|M.tuberculosis_H37Rv ------MRVAVVAGPDPGHSFPAIALCQRFRAAADTPTLFTGVEWLEAAR
MLBr_00985|M.leprae_Br4923 --MVHYMRVAVVAGPDPGHSFPAIALCQRFAEAGDTPTLFTGVECVDIAR
MAB_3062c|M.abscessus_ATCC_199 ------MRVAVVAGPDPGHAFPALALCLKFAAAGDDPVLLTGTRWLDQAR
Mflv_2592|M.gilvum_PYR-GCK --MNAMPDILITACPPVGHIGPLLNVAHGLVAHGHRVTVLTSARHADKIR
Mvan_4034|M.vanbaalenii_PYR-1 -----MPEILIATCPPVGHLSPLLNVARGLVARGDRVTVLTSARHADKIR
MSMEG_0730|M.smegmatis_MC2_155 MFPRAGLHICVVAASAPSHMYPHLPVVRELVERGHRVSYVVGAHRAELVR
TH_4587|M.thermoresistible__bu -----VAHIVFAVPVGVGHVNPTLGVAAELIARGHRVSYAATERHAARIA
: ... .* * : : : .. . .
MMAR_1974|M.marinum_M AAGVDAIELAGLVA--TDEDLDAG----------ARIHRRAAQMALLNAP
MUL_3383|M.ulcerans_Agy99 AAGVDAIELAGLVA--TDEDLDAG----------ARIHRRAAQMALLNAP
MAV_3631|M.avium_104 GAGVDAVELDGLAA--TDEDVDAG----------ARIHRRAARMAVLNVP
Mb2759c|M.bovis_AF2122/97 AAGIDAVELDGLAA--TDRDLDAG----------ARIHRRAAQMAVLNVP
Rv2739c|M.tuberculosis_H37Rv AAGIDAVELDGLAA--TDRDLDAG----------ARIHRRAAQMAVLNVP
MLBr_00985|M.leprae_Br4923 AAGVETALLDGLVA--VDDDVDAG----------ARIHRRAAQMAVLNVP
MAB_3062c|M.abscessus_ATCC_199 AAGVESVELLGLQPRVDDDDADSG----------AKIHQRAAHMALANLD
Mflv_2592|M.gilvum_PYR-GCK AVGADPRPLP-YGADYDDARLDADLPGRAHTSGIARINFDVEHVFVRPMP
Mvan_4034|M.vanbaalenii_PYR-1 AVGAEPRPLP-HAADYDDSTLDADLPGRAATAGLARINFDIESIFVRPLP
MSMEG_0730|M.smegmatis_MC2_155 DTGADVIGCTSVLPG-APGGPESWDDDGDPVRGMQLFLDEAIHVLPQLHA
TH_4587|M.thermoresistible__bu DVGARLVPYATTLSG-PEPPPQ--FTARDFHRATEAALRETGHVLPQVLD
.* . : :
MMAR_1974|M.marinum_M ALSDLAPDLVVSDVITACGG-----------MAAERLGIPWIELNPHPLY
MUL_3383|M.ulcerans_Agy99 ALSDLAPDLVVSDVITACGG-----------MAAERLGIPWIELNPHPLY
MAV_3631|M.avium_104 ALRDLAPDLVVSDVITAGGG-----------MAAELLGIPWIELSPHPLY
Mb2759c|M.bovis_AF2122/97 RLRALEPELVVSDVITACGG-----------MAAELLGIPWVELNPHPLY
Rv2739c|M.tuberculosis_H37Rv RLRALEPELVVSDVITACGG-----------MAAELLGIPWVELNPHPLY
MLBr_00985|M.leprae_Br4923 VLRDLAPDLIVSDVITAAGG-----------MAAELLGIPWIELNPHPLY
MAB_3062c|M.abscessus_ATCC_199 QLRALAPDLIVSDVITACGG-----------MAGELLGVPWVELNPHPLY
Mflv_2592|M.gilvum_PYR-GCK YQFSAVQELLAANSFDAVITDAFFLGVIPLLLDPTLARPPIMAYSTTPLF
Mvan_4034|M.vanbaalenii_PYR-1 HQFSALQELLVTDRFDAVIADALFLGTLPLLLGDPAKRPPILSYSTTPLF
MSMEG_0730|M.smegmatis_MC2_155 ALDDDRPDLVLYDIG-GMAGP----------VAADQWGVPAAQLSPSEVA
TH_4587|M.thermoresistible__bu GFAGDRPDLVLHDATMAWWGR----------LAAAAWEVPVVAGWPNLVG
:*: : . : * . :
MMAR_1974|M.marinum_M RPSKGLPPIGSGLAPGTGIRGRLRDTTMRALT-ARSWRAGLRQRAAVRAE
MUL_3383|M.ulcerans_Agy99 RPSKGLPPIGSGLAPGTGIRGRLRDTTMRALT-ARSWRAGLRQRAAVRAE
MAV_3631|M.avium_104 LPSKGLPPIGSGLATGTGLRGRLRDATMRALT-ARSWRAGLRQRAAARAE
Mb2759c|M.bovis_AF2122/97 LPSKGLPPIGSGLAAGTGIRGRLRDATMRALT-GRSWRAGLRQRAAVRVE
Rv2739c|M.tuberculosis_H37Rv LPSKGLPPIGSGLAAGTGIRGRLRDATMRALT-GRSWRAGLRQRAAVRVE
MLBr_00985|M.leprae_Br4923 LPSKGLPPIGSGLASGVGIHGRMRDATMRALT-ARSWRAGLRERAAVRVQ
MAB_3062c|M.abscessus_ATCC_199 LPSKGLPPLGSGLAPGVGLRGRLRDGLMRRLT-QKSIDQGLRQRSQARVE
Mflv_2592|M.gilvum_PYR-GCK LSSRDTAPAGPGILPMPGAVGRLRNRLLGLLSRAVLLRPAHRSAERMLRA
Mvan_4034|M.vanbaalenii_PYR-1 LTSRDTAPAGPGIAPMPGMIGRLRNRVLARATQSVLLRPGQRAADRMLEA
MSMEG_0730|M.smegmatis_MC2_155 WDGYHED--------MAEVLGPLLNSPSGQAYRRTFDDWLARSH--TSLT
TH_4587|M.thermoresistible__bu NRHWSMN--------RYIKVNPLHPRLLWNLWR---AHRLARRHGLTGLS
. : *
MMAR_1974|M.marinum_M IGLAEH-------DPGPLRRLIATLPALEVPRPDWPAEAIVVGPLHFEPT
MUL_3383|M.ulcerans_Agy99 IGLAEH-------DPGPLRRLIATLPALEVPRPDWPAEAIVVGPLHFEPT
MAV_3631|M.avium_104 IGLPAR-------DPGPLRRLIATLPALEVPRPDWPDEAVLVGPLHFEPT
Mb2759c|M.bovis_AF2122/97 IGLPAR-------DPGPLRRLIATLPALEVPRPDWPAEAVVVGPLHFEPT
Rv2739c|M.tuberculosis_H37Rv IGLPAR-------DPGPLRRLIATLPALEVPRPDWPAEAVVVGPLHFEPT
MLBr_00985|M.leprae_Br4923 IGLPAC-------DSGPLRRLIATLPALEVSRPDWPAEAVVVGPLHFEPT
MAB_3062c|M.abscessus_ATCC_199 IGLPAR-------DPGPMRRLIATLPALEVPRPDWPAEAVVVGPLHWEPT
Mflv_2592|M.gilvum_PYR-GCK MGLPDLPVFVLECAILADRVIVPTVPDFEYPRRDLPAHVRFVGAVSPLPG
Mvan_4034|M.vanbaalenii_PYR-1 MGLPELPVFILDSAVLADRVIVPTVPEFEYRRSDLPSHVRFVGPVSPLPG
MSMEG_0730|M.smegmatis_MC2_155 FDEVTG---------APHRCLVLIPRVMQRHADRVGDRYRFVGPCIDPRR
TH_4587|M.thermoresistible__bu LVRAT----------AADAQLVYLPREFQYAGDTFGAHYAFVGPCLVDRP
: . :: :: . .**.
MMAR_1974|M.marinum_M DQLLK------VPAGSGPVLVIAPSTALSGTAGLAEVALESLIPGDTLPS
MUL_3383|M.ulcerans_Agy99 DQLLK------VPAGSGPVLVIAPSTALSGTAGLAEVALESLIPGGTLSS
MAV_3631|M.avium_104 DRVLD------IPAGSGPVVVVAPSTAQTGARGLAEVALSCLTPGETLPA
Mb2759c|M.bovis_AF2122/97 DRVLA------IPAGTGPVVVVAPSTALTGTAGLTEVALQSLTPGETVPS
Rv2739c|M.tuberculosis_H37Rv DRVLA------IPAGTGPVVVVAPSTALTGTAGLTEVALQSLTPGETVPS
MLBr_00985|M.leprae_Br4923 DRVLQ------IPSGSGPVIVVAPSTALTGISGMAQTALDALVPGDTLPS
MAB_3062c|M.abscessus_ATCC_199 DVVLQ------PPSGSGPVVVIAPSTAFTGAEGMTELAVQALES-----A
Mflv_2592|M.gilvum_PYR-GCK DDFIAPAWWGELYRGRPVVHVTQGTVDNADLTRLIEPTIEALAGEDVTVV
Mvan_4034|M.vanbaalenii_PYR-1 SDFVAPPWWGELNAGRPVVHVTQGTIDNADLTRLIEPTIEALADEDVTVV
MSMEG_0730|M.smegmatis_MC2_155 EDPGDWTP--PAG-DGP-LALLAFGTSYTDRADVYRHVITALDGLGWRLV
TH_4587|M.thermoresistible__bu SD-GEWRP--PPGRDGRRVVLIALGTAYHDRADFFRTCLAAFADSGWHVV
. . : : . . . : .:
MMAR_1974|M.marinum_M GSRLVVSRLGGDDLVTPSWAAVGLGSQAELLTHADVVICGGGHGMVSKTL
MUL_3383|M.ulcerans_Agy99 GSRLVVSRLGGDDLVTPSWAAVGLGSQAELLTHADVVICGGGHGMVSKTL
MAV_3631|M.avium_104 GARLVVSRLAGPELAAPPWAVVGLGSQAELLRHADVVVCGGGHGMVAKTL
Mb2759c|M.bovis_AF2122/97 GSRLVVSRLSGADLTVPPWAVAGLGSQAELLTRADLVICGGGHGMVAKTL
Rv2739c|M.tuberculosis_H37Rv GSRLVVSRLSGADLTVPPWAVAGLGSQAELLTRADLVICGGGHGMVAKTL
MLBr_00985|M.leprae_Br4923 GSRVVVSRLNGPDLTVPSWAVAGLVHQTKLLAHADVVICGGGHGMVAKTL
MAB_3062c|M.abscessus_ATCC_199 GARVVISALEPPSSGLPSWAIAGLARQDLLLSGADLAVCGGGHGFLSKAL
Mflv_2592|M.gilvum_PYR-GCK VSTGGRPVSQIRTPLPANTFVAEFLPHDVLLPLVDVLVTNGGYGAVQRAL
Mvan_4034|M.vanbaalenii_PYR-1 ATTGGRPISQIRIPLPANTFVAKYVPHDVLLPMVDVMVTNGGYGAVQRAL
MSMEG_0730|M.smegmatis_MC2_155 LATG-RGELGGLGTVPDWVQLRDTVPQPAVLRVADAFFTHAGMGSCTEGL
TH_4587|M.thermoresistible__bu LAVGDRVDPAGLGPVPPHVEVHASVPQLQVLRHASVFVSHAGMGSVMEAL
: : :* .. . .* * . *
MMAR_1974|M.marinum_M LAGVPLVVVPGGGDQWEIANRVVRQGSARLIRP--LGAEALAAAVNEVLS
MUL_3383|M.ulcerans_Agy99 LAGVPLVVVPGGGDQWEIANRVVRQGSARLIRP--LGADALAAAVNEVLS
MAV_3631|M.avium_104 LAGVPLVAVPGGGDQWEIANRVVRQGSARLIRP--LSADALVAAVNEVLS
Mb2759c|M.bovis_AF2122/97 LAGVPMVVVPGGGDQWEIANRVVRQGSAVLIRP--LTADALVAAVNEVLS
Rv2739c|M.tuberculosis_H37Rv LAGVPMVVVPGGGDQWEIANRVVRQGSAVLIRP--LTADALVAAVNEVLS
MLBr_00985|M.leprae_Br4923 LAGVPLVVVPGGGDQWEMANRVVRQGSAQLIRP--LTAAALLAAVNKVLS
MAB_3062c|M.abscessus_ATCC_199 LAGVPTVVVPGGGDQWELANRVVRQGSAELVRP--LSRDSLASAIGRVLG
Mflv_2592|M.gilvum_PYR-GCK AEGVPLVVAGDTEDKPEVAARVEYFGVGVNLRTGTPAPQDLRDAVNAVLS
Mvan_4034|M.vanbaalenii_PYR-1 SDGVPVVVAGHTEDKPEVAARVRHFGVGIDLRTGTPTPTQVRRAVRKVLH
MSMEG_0730|M.smegmatis_MC2_155 WYGVPMVAMPQAVDQPDNAARLQGIGAGVHLQAHLPEPAEIRQALLYVTS
TH_4587|M.thermoresistible__bu AHRVPIVAVPQMTEQQANADRIAELNLGVRLGRDEITADRLRSAVERVAG
** *. :: * *: . . : : *: *
MMAR_1974|M.marinum_M SPGYREAAQRAAASIAD---VADPVQVCHEALALAG------
MUL_3383|M.ulcerans_Agy99 SPGYREAAQRAAASIAD---VADPVQVCHEALALAG------
MAV_3631|M.avium_104 SPGYRAAAQRAAAGIAD---VADPVRVCREALAG--------
Mb2759c|M.bovis_AF2122/97 SPRFREAARRAAASVAG---AADPVRVCHDALALAG------
Rv2739c|M.tuberculosis_H37Rv SPRFREAARRAAASVAG---AADPVRVCHDALALAG------
MLBr_00985|M.leprae_Br4923 SPDYREAAQRAAISIAG---VADPVQVCHEALGLAG------
MAB_3062c|M.abscessus_ATCC_199 EPRYREAARRAAAGAIA---VEDPVRVCQDVLAALR------
Mflv_2592|M.gilvum_PYR-GCK DAGYRTRAGRLQAAYASRDSVTAIAALLDEVIPEQAAAR---
Mvan_4034|M.vanbaalenii_PYR-1 EPGFRTKAGWLRSAYAAYDSVAEIAKLVDEAVAQRTQPLQSA
MSMEG_0730|M.smegmatis_MC2_155 DPRVRLRLNGIREEIRAHGGPAHAADAVEDVAAGRW------
TH_4587|M.thermoresistible__bu SATIAAAVRTMHDAITAAGGAAAAADIVEDVLTRSR------
.. . :.