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M. thermoresistible (build 8) TH_4567 (-)

annotation: epoxide hydrolase
coordinates: 4204268 - 4205014
length: 249

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4567--100% (249)epoxide hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_1749-2e-6874.00% (150) epocide hydrolase domain-containing protein
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_3314-1e-6976.67% (150) hydrolase
M. avium 104MAV_2202-8e-7178.00% (150) epoxide hydrolase
M. smegmatis MC2 155MSMEG_5658-1e-7079.33% (150) epoxide hydrolase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4998-2e-6876.67% (150) epocide hydrolase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1749|M.gilvum_PYR-GCK          --MAHIQPFRIDVPDSVLTDLAERLQRTRWPEPECVDDWSQGIPLAYTRE
Mvan_4998|M.vanbaalenii_PYR-1       --MAHIQPFRIAIPDADLADLTARLQRTRWPEAECVDDWSQGIPLSYTRE
MMAR_3314|M.marinum_M               -----MRPFRIDVPDDVIDDLKARLTRTRWPEAECVDDWSQGIPLSYTRD
MAV_2202|M.avium_104                -----MKPFRIDVPDDVLDDLRARLARTRWPEAECVDDWSQGMPLAYTRE
MSMEG_5658|M.smegmatis_MC2_155      MTDSLIRPFRIAVPDADLDDLKSRLSRTRWPEPETVDDWGQGIPLDYTRE
TH_4567|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_1749|M.gilvum_PYR-GCK          LADYWANEYDWRSRESMLNRFDQFTTEIDGLDIHFVHQRSPRPDAFPLII
Mvan_4998|M.vanbaalenii_PYR-1       LAAYWADEYDWRAREASLNRFEQFTTEIDGLPIHFIHARSTRPDAFPLII
MMAR_3314|M.marinum_M               LAAYWANEYDWRAREAALNRFDQFITEIDGLDLHFIHQRSPHQDAFPLLI
MAV_2202|M.avium_104                LADYWANDYDWRAREAALNRFDQFVTEIDGLDIHFIHQRSPHADAFPLLI
MSMEG_5658|M.smegmatis_MC2_155      LAEYWANGYDWRAREQALNRFDHYVTELDGLDIHFIHQRCARPDAFPLLL
TH_4567|M.thermoresistible__bu      --------------------------------VVIVSATAWRIVGYAGLI
                                                                    : ::   . :  .:. ::

Mflv_1749|M.gilvum_PYR-GCK          THGWPGSIVEFQKVIAPLT---------EAGFHVVCPSLPGYGFSGKPTA
Mvan_4998|M.vanbaalenii_PYR-1       THGWPGSVVEFHKVIEPLT---------DAGFHVVCPSLPGYGFSGKPRS
MMAR_3314|M.marinum_M               THGWPGSVVEFHKVIEPLTNPTAHGGRAEDAFHVVCPSLPGYGFSGKPSS
MAV_2202|M.avium_104                THGWPGSIVEFHKVIEPLTNPAS--GRGEDAFHVVCPSLPGYGFSGKPTR
MSMEG_5658|M.smegmatis_MC2_155      THGWPGSIVEFHKVIEPLT---------EAGFDVVCPSLPGYGFSGKPTT
TH_4567|M.thermoresistible__bu      AGG-----VWLAQATAPVAG-----------------AQPGDDDSGD-SG
                                    : *     * : :.  *::                  : ** . **.   

Mflv_1749|M.gilvum_PYR-GCK          TGWGVERIAAAWDELMVRLGYDRYGAQGGDWGAAVTTQIGRNVGHCVAIH
Mvan_4998|M.vanbaalenii_PYR-1       TGWGVERIAAAWDELMVRLGYRRYGAQGGDWGGAVTTQIGRNIGHCVAIH
MMAR_3314|M.marinum_M               TGWGVDRIARAWETLMQNLGYQRYGAQGGDWGAAVTTQIGRNGGRCVAIH
MAV_2202|M.avium_104                AGWGVERIARAWETLMLRLGYQRYGAQGGDWGAAVTTQIGRNRGHCVAIH
MSMEG_5658|M.smegmatis_MC2_155      TGWGIGRIAQAWDTLMTRLGYDRYGAQGGDWGAAVTTQIGRNVGNCVGIH
TH_4567|M.thermoresistible__bu      AGRSSQ---SATPAASAQAGSARAGSS--QAGSPRTADARRN--------
                                    :* .      *      . *  * *:.  : *.. *::  **        

Mflv_1749|M.gilvum_PYR-GCK          TNMPFGRPPK-SLSDPDADEVAALERLGYYQKWDSGYSKQQATRPQTLGY
Mvan_4998|M.vanbaalenii_PYR-1       TNMPIGRAPK-DLSDPTPDEQAALERLGYYQRWDSGYSKQQSTRPQTLGY
MMAR_3314|M.marinum_M               LNMPIAMPTRTALTNPTAAEQEVLAALAYHRKWGTGYFKQQSTRPQTVGY
MAV_2202|M.avium_104                LNMPIGRPGQEALTNPTEQERAALAALANHRKRGTGYSKQQSTRPQTLGY
MSMEG_5658|M.smegmatis_MC2_155      VNMPIARPPAEGVGEMTEEVRQALERMQYYRKWDSGYMKQQSTRPQTVGY
TH_4567|M.thermoresistible__bu      -----GSPVRFGAGRGPIXX--------XYRRWDSGYAKQQSTRPQTLGY
                                         . .                     ::: .:** ***:*****:**

Mflv_1749|M.gilvum_PYR-GCK          GLVDSPVAQMAWIVEKFWSWMDCDGHPENVLTKDELLDNVMLYWATATGA
Mvan_4998|M.vanbaalenii_PYR-1       GLVDSPVGQLAWIVEKFWSWTDCDGHPENALTRDELLDNVMLYWATGTGA
MMAR_3314|M.marinum_M               GLTDSPVGQLAWIVEKFWAWMDCAGNPENVLTRDELLDNVMMYWVNAAAA
MAV_2202|M.avium_104                GLADSPVGQLAWIVEKFWDWADCDGHPENALSRDELLDNVMVYWVTNTAA
MSMEG_5658|M.smegmatis_MC2_155      GLVDSPVGQLAWIVEKFWSWMDCDGHPENVLSRDELLDNVMLYWVTASAA
TH_4567|M.thermoresistible__bu      GLVDSPVGQLAWIVEKFWAWTDCDGHPENVLSRDELLDNVMLYWVTGSAA
                                    **.****.*:******** * ** *:***.*::********:**.. :.*

Mflv_1749|M.gilvum_PYR-GCK          SSARLYWESFGAFGGGDPVTLPTGVASFPKEILRSPRHWCEGNYTITRWT
Mvan_4998|M.vanbaalenii_PYR-1       SSARLYWESFGSFAGGGAVTLPTGVAAFPLEILRSPRHWCEPHYNITRWT
MMAR_3314|M.marinum_M               SSARLYWESFKVWGQTERVELPTGVASFPKEVLRAPRAWCEPNYNITHWT
MAV_2202|M.avium_104                SSARLYWESFSAWGGGDRVELPTGVAAFPGELLKAPRSWCEPAYNITHWT
MSMEG_5658|M.smegmatis_MC2_155      SSARLYWESYDTFAGGDFVTLPTGVASFPKEILRAPRAWCEKAYNVTHFT
TH_4567|M.thermoresistible__bu      SSARLYWESFAVFGSTDRVRVPTGVARFPREINQAPRHWCEAIYPITHWT
                                    *********:  :.    * :***** ** *: ::** ***  * :*::*

Mflv_1749|M.gilvum_PYR-GCK          TMPRGGHFAAFEQPSSFVDDVAAFFDDFR
Mvan_4998|M.vanbaalenii_PYR-1       TMPRGGHFAAFEQPGPFVEEVGSFFADFR
MMAR_3314|M.marinum_M               TMPRGGHFAAFEQPELFVGDVRAFFATVR
MAV_2202|M.avium_104                DMPRGGHFAAFEQPELFVEDLRVFFATVR
MSMEG_5658|M.smegmatis_MC2_155      MMPRGGHFAAFEQPELFVEDVAKFFDSVR
TH_4567|M.thermoresistible__bu      DMPRGGHFAAFEQPELFVEDVRTFFRTIR
                                     *************  ** ::  **  .*