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M. avium 104 MAV_1022 (-)

annotation: two component response transcriptional regulatory protein prra
coordinates: 958145 - 958846
length: 233

DTAASSPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEALRSATETRPDAIVLDINMPVLDGVSVVT
ALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETITVGP
LEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKL
EANGGPRLLHTVRGVGFVLRMQ*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_1022 - - 100% (233) two component response transcriptional regulatory protein prra
M. avium 104 MAV_1094 - 2e-57 51.12% (223) two component response transcriptional regulatory protein MprA
M. avium 104 MAV_0701 phoP 1e-50 45.85% (229) DNA-binding response regulator PhoP

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0927c prrA 1e-123 97.00% (233) two component response transcriptional regulatory protein
M. gilvum PYR-GCK Mflv_1744 - 1e-118 95.63% (229) two component transcriptional regulator
M. tuberculosis H37Rv Rv0903c prrA 1e-123 97.00% (233) two component response transcriptional regulatory protein
M. leprae Br4923 MLBr_02123 - 1e-123 97.00% (233) two-component response regulator
M. abscessus ATCC 19977 MAB_0956c - 1e-115 93.39% (227) transcriptional regulatory protein PrrA
M. marinum M MMAR_4633 prrA 1e-125 99.14% (233) two-component response transcriptional regulatory protein
M. smegmatis MC2 155 MSMEG_5662 prrA 1e-118 93.64% (236) DNA-binding response regulator PrrA
M. thermoresistible (build 8) TH_4543 - 1e-115 96.40% (222) PUTATIVE two component transcriptional regulator, winged helix
M. ulcerans Agy99 MUL_0248 prrA 1e-124 98.71% (232) two component response transcriptional regulatory protein
M. vanbaalenii PYR-1 Mvan_5009 - 1e-120 94.85% (233) two component transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1744|M.gilvum_PYR-GCK          ---MDS-----GSPRVLVVDDDPDVLASLERGLRLSGFDVFTAVDGAEAL
Mvan_5009|M.vanbaalenii_PYR-1       ---MDSGA---GSPKVLVVDDDPDVLASLERGLRLSGFDVYTAVDGAEAL
MSMEG_5662|M.smegmatis_MC2_155      ---MDSTTSGMASPRVLVVDDDPDVLASLERGLRLSGFDVSTAVDGAEAL
TH_4543|M.thermoresistible__bu      -----------------VVDDDPDVLASLERGLRLSGFEVSTAVDGAEAL
Mb0927c|M.bovis_AF2122/97           MGGMDTGVT---SPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEAL
Rv0903c|M.tuberculosis_H37Rv        MGGMDTGVT---SPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEAL
MMAR_4633|M.marinum_M               MGGMDTGAN---SPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEAL
MUL_0248|M.ulcerans_Agy99           MGGMDTGAN---SPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEAL
MAV_1022|M.avium_104                ---MDTAAS---SPRVLVVDDDSDVLASLERGLRLSGFEVSTAVDGAEAL
MLBr_02123|M.leprae_Br4923          ---MDTGVS---SPRVLVVDDDSDVLASLERGLRLSGFEVSTAIDGAEAL
MAB_0956c|M.abscessus_ATCC_199      ---MVDGQG---SPRVLVVDDDADVLASLERGLRLSGFEVNTASDGAEAL
                                                     *****.***************:* ** ******

Mflv_1744|M.gilvum_PYR-GCK          RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
Mvan_5009|M.vanbaalenii_PYR-1       RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MSMEG_5662|M.smegmatis_MC2_155      RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
TH_4543|M.thermoresistible__bu      RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
Mb0927c|M.bovis_AF2122/97           RSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
Rv0903c|M.tuberculosis_H37Rv        RSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MMAR_4633|M.marinum_M               RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MUL_0248|M.ulcerans_Agy99           RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MAV_1022|M.avium_104                RSATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MLBr_02123|M.leprae_Br4923          RNATETRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDR
MAB_0956c|M.abscessus_ATCC_199      RCATEHRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARTSVDDR
                                    * *** **************************************:*****

Mflv_1744|M.gilvum_PYR-GCK          VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATFSSETITVGPLEV
Mvan_5009|M.vanbaalenii_PYR-1       VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATFSSETITVGPLEV
MSMEG_5662|M.smegmatis_MC2_155      VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSSATFSSETIQVGPLEV
TH_4543|M.thermoresistible__bu      VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSSATSSSETIVVGPLEV
Mb0927c|M.bovis_AF2122/97           VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSETITVGPLEV
Rv0903c|M.tuberculosis_H37Rv        VAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSETITVGPLEV
MMAR_4633|M.marinum_M               VAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETITVGPLEV
MUL_0248|M.ulcerans_Agy99           VAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSEIITVGPLEV
MAV_1022|M.avium_104                VAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETITVGPLEV
MLBr_02123|M.leprae_Br4923          VAGLEAGADDYLVKPFVLAELVARVKALLRRRGATATSSSETIAVGPLEV
MAB_0956c|M.abscessus_ATCC_199      VAGLEAGADDYLTKPFVLAELVARVKALLRRRGAVATSSTETITVGPLEV
                                    ************.********************: ** *:* * ******

Mflv_1744|M.gilvum_PYR-GCK          DIPGRRARVDGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
Mvan_5009|M.vanbaalenii_PYR-1       DIPGRRARVDGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MSMEG_5662|M.smegmatis_MC2_155      DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
TH_4543|M.thermoresistible__bu      DIPGRRARVNGQDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
Mb0927c|M.bovis_AF2122/97           DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
Rv0903c|M.tuberculosis_H37Rv        DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MMAR_4633|M.marinum_M               DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MUL_0248|M.ulcerans_Agy99           DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MAV_1022|M.avium_104                DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
MLBr_02123|M.leprae_Br4923          DIPGRRARVNGVDVDLTKREFDLLAVLAEHKTTVLSRAQLLELVWGYDFA
MAB_0956c|M.abscessus_ATCC_199      EIPGRRARINGVEVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFA
                                    :*******::* :*******************:*****************

Mflv_1744|M.gilvum_PYR-GCK          ADTNVVDVFIGYLRRKLEANGAPRLLHTVRGVGFVLRQQ
Mvan_5009|M.vanbaalenii_PYR-1       ADTNVVDVFIGYLRRKLEANGAPRLLHTVRGVGFVLRQQ
MSMEG_5662|M.smegmatis_MC2_155      ADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRTQ
TH_4543|M.thermoresistible__bu      ADTNVVDVFIGYLRRKLEATGAPRLLHTVRGVGFVLRTQ
Mb0927c|M.bovis_AF2122/97           ADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
Rv0903c|M.tuberculosis_H37Rv        ADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
MMAR_4633|M.marinum_M               ADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ
MUL_0248|M.ulcerans_Agy99           ADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMH
MAV_1022|M.avium_104                ADTNVVDVFIGYLRRKLEANGGPRLLHTVRGVGFVLRMQ
MLBr_02123|M.leprae_Br4923          ADTNVVDVFIGYLRRKLEANSGPRLLHTVRGVGFVLRMQ
MAB_0956c|M.abscessus_ATCC_199      ADTNVVDVFIGYLRRKLEAGGAPRLLHTVRGVGFVLRSQ
                                    ******************* ..*************** :

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_1022	-	-	100% (233)	two component response transcriptional regulatory protein prra
M. avium 104	MAV_1094	-	2e-57	51.12% (223)	two component response transcriptional regulatory protein MprA
M. avium 104	MAV_0701	phoP	1e-50	45.85% (229)	DNA-binding response regulator PhoP