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M. thermoresistible (build 8) TH_4534 (-)

annotation: oxidoreductase, 2-nitropropane dioxygenase family protein
coordinates: 4695497 - 4696489
length: 331

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4534--100% (331)oxidoreductase, 2-nitropropane dioxygenase family protein
M. thermoresistible (build 8)TH_1758-1e-2636.86% (236) POSSIBLE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_1976-5e-1933.75% (240) oxidoreductase, 2-nitropropane dioxygenase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3583-6e-2535.78% (232) oxidoreductase
M. gilvum PYR-GCKMflv_5156-3e-2336.29% (248) 2-nitropropane dioxygenase, NPD
M. tuberculosis H37RvRv3553-6e-2535.78% (232) oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0603c-2e-2333.19% (232) 2-nitropropane dioxygenase
M. marinum MMMAR_5042-4e-2535.59% (236) 2-nitropropane dioxygenase
M. avium 104MAV_4991-1e-11062.27% (326) oxidoreductase, 2-nitropropane dioxygenase family protein
M. smegmatis MC2 155MSMEG_1660-4e-2639.33% (239) oxidoreductase, 2-nitropropane dioxygenase family protein
M. ulcerans Agy99MUL_4116-4e-2535.59% (236) 2-nitropropane dioxygenase
M. vanbaalenii PYR-1Mvan_5269-5e-2434.91% (232) 2-nitropropane dioxygenase, NPD

CLUSTAL 2.0.9 multiple sequence alignment


MAB_0603c|M.abscessus_ATCC_199      MTQVLKTALTQLVGIEHPVVQTGMG-WVAGPRLVAATSNAGGLGILASAT
Mvan_5269|M.vanbaalenii_PYR-1       -MSRLSTPLTELVGIEHPVVQTGMG-WVAGARLVSATSNAGGLGILASAT
Mb3583|M.bovis_AF2122/97            --MRLRTPLTELIGIEHPVVQTGMG-WVAGARLVSATANAGGLGILASAT
Rv3553|M.tuberculosis_H37Rv         --MRLRTPLTELIGIEHPVVQTGMG-WVAGARLVSATANAGGLGILASAT
MMAR_5042|M.marinum_M               --MRLRTPLTDLVGVEHPVVQTGMG-WVAGARLVSATANAGGLGILASAT
MUL_4116|M.ulcerans_Agy99           --MRLRTPLTDLVGVEHPVVQTGMG-WVAGARLVSATANAGGLGILASAT
Mflv_5156|M.gilvum_PYR-GCK          -MDTLSTPWSAELGLDVPIVNAPMG-GAAGGTLAAAVSRAGGLGMVGMGS
MSMEG_1660|M.smegmatis_MC2_155      --MSLATTWSKAMGIDVPIVNAPMG-GAAGARLAAAVSEAGGLGMVGMGS
TH_4534|M.thermoresistible__bu      ------VDVLDRLRLDVPVAQAGMGGGLAGPELAVAVADAGGLGTLGLTA
MAV_4991|M.avium_104                ------MDIADRLRLDVPVGQAGMGGGLAGAPLAAAVAAAGGLGTLGITT
                                                : :: *: :: **   **  *. *.: ***** :.  :

MAB_0603c|M.abscessus_ATCC_199      MTLDELIAAVAKTKSLTDKPFGVNIRADAGDAT-ERIDLLIREKVKVASF
Mvan_5269|M.vanbaalenii_PYR-1       MTLEELTTAVAKVKAATDKPFGINIRADAGDAN-ARVDLLIREGVKVASF
Mb3583|M.bovis_AF2122/97            MTLDELAAAITKVKAVTDKPFGVNIRADAADAG-DRVELMIREGVRVASF
Rv3553|M.tuberculosis_H37Rv         MTLDELAAAITKVKAVTDKPFGVNIRADAADAG-DRVELMIREGVRVASF
MMAR_5042|M.marinum_M               MTLDELATAIGKVKATTDKPFGVNIRADAADAS-DRVELMIREGVKVASF
MUL_4116|M.ulcerans_Agy99           MTLDELATAIGKVKATTDKPFGVNIRADAADAS-DRVELMIREGVKVASF
Mflv_5156|M.gilvum_PYR-GCK          SASAAQLRAQLAELGELKRPFGIGVIDWVIRKEPELLTTALDARPTALSV
MSMEG_1660|M.smegmatis_MC2_155      SATPEQLRRELADLAKPSRPFGIGLVHWVMTERPDLFDIALEARPALLSV
TH_4534|M.thermoresistible__bu      PDRLRDGIRRVRAEAP-GRAVAVNLLMPFVRRP--HVRVCVEERIDVAVV
MAV_4991|M.avium_104                PGRLEASIQRVREQAP-GRAVAVNLLLPFTRRR--HVAVCVEARVDVVVL
                                                  .   :...:.:           .   :        .

MAB_0603c|M.abscessus_ATCC_199      ALAPKQDLIAKLKDNGVVVVPSIGAAKHAKKVAAWGADAVIVQGGEGGGH
Mvan_5269|M.vanbaalenii_PYR-1       ALAPKPDLIARLKDAGVVVIPSVGLAKHAKKVAGWGADAVIVQGGEGGGH
Mb3583|M.bovis_AF2122/97            ALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEGGGH
Rv3553|M.tuberculosis_H37Rv         ALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEGGGH
MMAR_5042|M.marinum_M               ALAPKPELIARLKEAGAVVIPSIGAAKHARKVAGWGADAMIVQGGEGGGH
MUL_4116|M.ulcerans_Agy99           ALAPKPELIARLKEAGAVVIPSIGAAKHARKVAGWGADAMIVQGGEGGGH
Mflv_5156|M.gilvum_PYR-GCK          SFGTEWDWVARARDAGCVSVTQVADVEAALRAVDAGVQVLVARGAEAGGH
MSMEG_1660|M.smegmatis_MC2_155      SFGDDWAWVRRAHDVGVTVATQVATVGDALRAAEAGVDVLVARGAEAGGH
TH_4534|M.thermoresistible__bu      AFGGDRALVRELRDAGVFVFTMVGTADQVRRALHWGVDALIAQGAEAGGH
MAV_4991|M.avium_104                AFGENRGLVAHLRQAGAFVFAMVGAVAQARAAIAWGADGLIAQGREAGGH
                                    ::. .   : . :: *    . :. .  .  .   *.: ::.:* *.***

MAB_0603c|M.abscessus_ATCC_199      TGPVATTL-LLPSVLDAVKDTGMPVVAAGGFFDGRGLAAALSYGAAGVAM
Mvan_5269|M.vanbaalenii_PYR-1       TGPIATTL-LLPSVLDAVADTGMPVIAAGGFFDGRGLAAALSYGAAGVAM
Mb3583|M.bovis_AF2122/97            TGPVATTL-LLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAAGVAM
Rv3553|M.tuberculosis_H37Rv         TGPVATTL-LLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAAGVAM
MMAR_5042|M.marinum_M               TGPVATTL-LLPSVLDAVKGTGIPVIAAGGFFDGRGLAAALSYGAAGVAM
MUL_4116|M.ulcerans_Agy99           TGPVATTL-LLPSVLDAVKGTGIPVIAAGGFFDGHGLAAALSYGAAGVAM
Mflv_5156|M.gilvum_PYR-GCK          GTPAVATLPLLAAILDRVE---VPVLAAGGIASGRALAAVLAAGAAGAWI
MSMEG_1660|M.smegmatis_MC2_155      GRPALGTLPLLTQVLDAVE---LPVLAAGGVASPRGLAAVLAAGAAAAWL
TH_4534|M.thermoresistible__bu      LVGESPAAAFLPKARDLAG--GRPVFLAGGVATAADTRAALDAGADAVVA
MAV_4991|M.avium_104                LVGTMAALDFLPHALAAAA--GRPVFLAGGIATAADSRAALDAGADGVIA
                                          :  :*.     .     **. ***.       *.*  ** ..  

MAB_0603c|M.abscessus_ATCC_199      GTRFLLTSDSSVPDGVKQRYLASDLAGTVVSTRVDGMPHRVLRTELVEKL
Mvan_5269|M.vanbaalenii_PYR-1       GTRFLLTSDSTVPDAVKQRYLDAALDGTVVSTKVDGMPHRVLRTGLVEKL
Mb3583|M.bovis_AF2122/97            GTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTELVEKL
Rv3553|M.tuberculosis_H37Rv         GTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTELVEKL
MMAR_5042|M.marinum_M               GTRFLLTSDSTVPEAVKRRYLQAALDGTVVTTRVDGMPHRVLRTGLVEKL
MUL_4116|M.ulcerans_Agy99           GTRFLLTSDSTVPDAVKRRYLQAALDGTVVTTRVDGMPHRVLRTGLVEKL
Mflv_5156|M.gilvum_PYR-GCK          GTAFATCPESLFPDEARRALLTADATDTLTTR------------------
MSMEG_1660|M.smegmatis_MC2_155      GTVFTTCVEASTPAAARDRLLAANGENTMLTS------------------
TH_4534|M.thermoresistible__bu      GTRFLLTHESGAHPEYQRRLLEAETTYRTMLFG--------LGWPAPHRV
MAV_4991|M.avium_104                GTRFLLTHEADASRGYQQRVLQADNTIETNLFG--------LSWPLRHRV
                                    ** *    ::      :   * :                           

MAB_0603c|M.abscessus_ATCC_199      ESGSRVRGFTAAVRNAAKFKKMTGMSWASMVKDGLAMRHGKELTWSQVLM
Mvan_5269|M.vanbaalenii_PYR-1       ESGSPIRGLSAAVLNAQKFKKMSGMTWKSMITDGLAMRHGKDLTWSQVVM
Mb3583|M.bovis_AF2122/97            ESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWSQVLM
Rv3553|M.tuberculosis_H37Rv         ESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWSQVLM
MMAR_5042|M.marinum_M               EGGSRARGFTAAIRNAAKFKQMSQMSWASMIKDGLAMRHGKELTWSQVVM
MUL_4116|M.ulcerans_Agy99           EGGSRARGFTAAIRNAAKFKQMSQMSWASMIKDGLAMRHGKELTWSQVLM
Mflv_5156|M.gilvum_PYR-GCK          -----------------VFDVALGYPWPAHFPERVLRNA-FTAAWDGRTP
MSMEG_1660|M.smegmatis_MC2_155      -----------------EFDIRAGYRWPADVPERVLT-------------
TH_4534|M.thermoresistible__bu      VGNAATRRWCDASGTAKRLPVWINARSEFMARLGDVPPA-VLVRWQRPAL
MAV_4991|M.avium_104                VPNAATRRWCGAHGKARALPAALNAASRPLSALGYFDAG-ALLRLQSPRR
                                                      :                               

MAB_0603c|M.abscessus_ATCC_199      AANTPMLLKAGLVEGNTNAGVLASGQVAGILDDLPSCHELIDAIVTDAVA
Mvan_5269|M.vanbaalenii_PYR-1       AANTPMLLKAGLVEGNTDAGVLASGQVAGIIDDLPSCAELVPAIVAEAVE
Mb3583|M.bovis_AF2122/97            AANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVLDAIT
Rv3553|M.tuberculosis_H37Rv         AANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVLDAIT
MMAR_5042|M.marinum_M               AANTPMLLKAGLVDGNPEAGVLASGQVAGILDDLPSCAQLVESIVHDAIE
MUL_4116|M.ulcerans_Agy99           AANTPMLLKAGLVDGNPEAGVLASGQVAGILDDLPSCAQLVESIVHDAIE
Mflv_5156|M.gilvum_PYR-GCK          DDDARARLAEAIADDDFRVAPVNAGQGVDDITAVEPAAMVIARLCDDARR
MSMEG_1660|M.smegmatis_MC2_155      -------------DENGAATPVNAGQGVGMVNQSLTVAETMSRLCWGAEA
TH_4534|M.thermoresistible__bu      PLFSPAAPTRAMPAAWVDRTALYAGESVLRMAAVIPARDAVAELSPAQGV
MAV_4991|M.avium_104                PLFTPLAPVAGVPDSLLDSAALYAGETASRIGELTSARQAVADLTPR---
                                                         : :*: .  :    .    :  :      

MAB_0603c|M.abscessus_ATCC_199      HLKAANATIL
Mvan_5269|M.vanbaalenii_PYR-1       HLQKASQHIR
Mb3583|M.bovis_AF2122/97            HLQTASALVE
Rv3553|M.tuberculosis_H37Rv         HLQTASALVE
MMAR_5042|M.marinum_M               HLRAAAALVE
MUL_4116|M.ulcerans_Agy99           HLRAAAALVE
Mflv_5156|M.gilvum_PYR-GCK          LLAKPPTR--
MSMEG_1660|M.smegmatis_MC2_155      LLRRWS----
TH_4534|M.thermoresistible__bu      ----------
MAV_4991|M.avium_104                ----------