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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4449 | - | - | 100% (341) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4265 | - | e-112 | 58.98% (334) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2568 | - | e-112 | 60.78% (334) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3528c | mce4B | 4e-72 | 40.99% (322) | MCE-family protein MCE4B |
| M. gilvum PYR-GCK | Mflv_4537 | - | 1e-112 | 61.38% (334) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv3498c | mce4B | 4e-72 | 40.99% (322) | MCE-family protein MCE4B |
| M. leprae Br4923 | MLBr_02590 | mce1B | 7e-59 | 36.15% (343) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4152c | - | 3e-70 | 41.23% (325) | MCE-family protein |
| M. marinum M | MMAR_4709 | - | 1e-110 | 59.23% (336) | MCE-family protein |
| M. avium 104 | MAV_0949 | - | 1e-110 | 58.53% (340) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_4793 | - | 1e-116 | 61.24% (338) | virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_4061 | mce4B | 1e-72 | 42.55% (322) | MCE-family protein Mce4B |
| M. vanbaalenii PYR-1 | Mvan_4149 | - | 1e-108 | 56.72% (335) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3528c|M.bovis_AF2122/97 MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFT
Rv3498c|M.tuberculosis_H37Rv MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFT
MUL_4061|M.ulcerans_Agy99 MASGGMPSHRSMVIKVSVFGVVMLVLAAALVVVFGDFRFGPTNVYHATFT
MAB_4152c|M.abscessus_ATCC_199 -------MKRATQIKVIVFTVVMLLVAAGLIITFGEFRFGSGKRYHAMFS
MSMEG_4793|M.smegmatis_MC2_155 -----MRRASSTLVKFGVFAVVMAVLTAFLFMTFSEYRGGSYAGYSAVFD
Mvan_4149|M.vanbaalenii_PYR-1 -----MTRSAATLVKFTAFGLVMALLTAFLFLVFSDTRTGAANEYTAVFK
MMAR_4709|M.marinum_M -----MTGSRAMIIKFGAFAAVMIVLTVFLFFIFGQYRTGSTNGYSALFN
MAV_0949|M.avium_104 -----MR-TRATLIKFAIFAVVMAMLTAFLFFIFGQYRTGATNGYSAVFT
Mflv_4537|M.gilvum_PYR-GCK -----MTDVGKAATKFAAFGLTMVVLTAGLFMIFGEYRSGAANRYSAVFT
TH_4449|M.thermoresistible__bu -----MT-AAAPVVKLGVFATVMVVLTAGLIMVFGDYRGGESRNYSAVFT
MLBr_02590|M.leprae_Br4923 ------MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFT
:. * .: :.:. :.. *.: * * * * *
Mb3528c|M.bovis_AF2122/97 DASRLKAGQKVRIAGVPVGSVKAVKLNPD-HSIDVAFAIDRSYTLYSSTR
Rv3498c|M.tuberculosis_H37Rv DASRLKAGQKVRIAGVPVGSVKAVKLNPD-HSIDVAFAIDRSYTLYSSTR
MUL_4061|M.ulcerans_Agy99 NASRLKAGQKVRIAGVPVGSVKAVDLNPD-NTIDVAFAIDRAYTMYSSTR
MAB_4152c|M.abscessus_ATCC_199 TASDLRSGQKVRIAGVPVGRVKNVSLNRD-NSVEVTFDVDSKYQLYSSSR
MSMEG_4793|M.smegmatis_MC2_155 DASRLESGDSVRVAGVRVGTVKNVSLQPD-RTVLVDFDTERNIALTTGTK
Mvan_4149|M.vanbaalenii_PYR-1 DASRLKTGDTVRIAGIRVGTVKDVELQAD-RSVLVTFDADRNTVLTTGTN
MMAR_4709|M.marinum_M DVSRLKPGETVRIAGVRVGTVNSVSLRTD-KKVLVKFDADRNIVLTTGTR
MAV_0949|M.avium_104 DVSRLKPGQSVRVAGIRVGTVNSVSLQPD-KKVVVKFDADRNIVLTEGTR
Mflv_4537|M.gilvum_PYR-GCK DSSSLTSGDSVRAAGIRVGTVRGVTLQDD-NTVVVDFDADDNVRLTEGTR
TH_4449|M.thermoresistible__bu DVSRLEVGDSVRIAGIRAGTVNRIRLRDD-HTVVVSFDVRRDVALTTGTT
MLBr_02590|M.leprae_Br4923 NISGLRTGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTT
* * *: ** :*: .* *. : * . : * * : .:
Mb3528c|M.bovis_AF2122/97 AVIRYENLVGDRFLEITSG--PGELRKLPPGGTINVAHTQPALDLDALLG
Rv3498c|M.tuberculosis_H37Rv AVIRYENLVGDRFLEITSG--PGELRKLPPGGTINVAHTQPALDLDALLG
MUL_4061|M.ulcerans_Agy99 AVIRYENLVGDRYLEITSG--PDELRKLPPGGTINAEHTQPALDLDALLG
MAB_4152c|M.abscessus_ATCC_199 AIIRYENLVGDRYLEITAG--PGELHKLPDGGTLDKEHTQPALDLDALLG
MSMEG_4793|M.smegmatis_MC2_155 AAVRYLNLVGDRYLELIDS--PGSTRLLPAGSQIPKERTASALDLDLLLG
Mvan_4149|M.vanbaalenii_PYR-1 AAIRYLNLVGDRYLELVDT--PDSTQIVPAGGQIPEDRTTPALDLDVLLG
MMAR_4709|M.marinum_M AVVRYLNLVGDRYLELVDG--PGSTKTLPAGSQIPIERTAGALDLDLLLG
MAV_0949|M.avium_104 AAVRYLNLVGDRYLELVDG--PGSPKRLPAGGQIPVSRTAPALDLDLLLG
Mflv_4537|M.gilvum_PYR-GCK IAVRYLNLVGDRYLELLDE--PGSARIQPSGSRIGLERTEPALNLDLLLG
TH_4449|M.thermoresistible__bu AAVRYLNLVGDRYLELRDG--PGPTGVLPAGAEIPRERTMPALDLDLLLG
MLBr_02590|M.leprae_Br4923 AQIRYLDLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIG
:** :*:*:*:**: . * *. : :* **:** *:*
Mb3528c|M.bovis_AF2122/97 GLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARD
Rv3498c|M.tuberculosis_H37Rv GLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARD
MUL_4061|M.ulcerans_Agy99 GLRPVLKGLDADKVNTVTGAVIELLQGQGGALANVLADTSAFSTALARRD
MAB_4152c|M.abscessus_ATCC_199 GLRPVLKGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERD
MSMEG_4793|M.smegmatis_MC2_155 GLKPVIQGLDPQDVNALTSSLIQIFQGQGDTLSSLMSKTSSFSNTLADND
Mvan_4149|M.vanbaalenii_PYR-1 GLKPVIQGLNPEDVNGLTSALIQILQGQGGTLDSLFSKTSSFSNSLADNN
MMAR_4709|M.marinum_M GLKPVTQGLNPQDVNALSASLIQIFQGEGSTLESLLSKTSSFTNALADNN
MAV_0949|M.avium_104 GLKPVTQGLNARDVNALTSGLLQVFQGQGGTLDSLFTKATSFSNALADND
Mflv_4537|M.gilvum_PYR-GCK GLKPVIQGLNPDDVNALTSSLIQILQGQGGNLESLFSRTSSFTNSLADNG
TH_4449|M.thermoresistible__bu GLKPVLRSLNPEDVNSFSASLVGILQGQGGTLESLLSRTSTFTTALADNG
MLBr_02590|M.leprae_Br4923 GFKPLFRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERD
*::*: :.::. .:* .: ..: :**:*. : .:: : :: :. ..
Mb3528c|M.bovis_AF2122/97 QLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAIS
Rv3498c|M.tuberculosis_H37Rv QLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAIS
MUL_4061|M.ulcerans_Agy99 QLIGDTITNLNSVLATVDQRSAQFSASVDQLQQLITGLAENKDVIAGAIP
MAB_4152c|M.abscessus_ATCC_199 QLIGDVINHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALP
MSMEG_4793|M.smegmatis_MC2_155 QVIGQLIENLDTVVDTLNRDGGKFSATVDRLEQLISGLSQDRDPIGTAVT
Mvan_4149|M.vanbaalenii_PYR-1 QVIEELIVDLRTVLDTLSKDGEEFSGAIDKLEQLVSGLSSDRDPIGTAIT
MMAR_4709|M.marinum_M ETVQALIDNLNVVVDTVNREGTKFSGAIDRLERLISALSQDRDTIGAAIT
MAV_0949|M.avium_104 QTVQQLIDNLNIVIGTISKDGKQFSGAVDRLERLVSGLSDDRNTIGSAID
Mflv_4537|M.gilvum_PYR-GCK QTVERLIDTLNETLATVSADGQNLSSAIDQLEQLATGLAQDRDPIGDAIT
TH_4449|M.thermoresistible__bu AVVQQVIDRLQTVLATLSERGPEFAAAVERLERFITELSVERDPIGSAIE
MLBr_02590|M.leprae_Br4923 QAIGEVVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFA
: : * .: * :: :::.*: : : * . : :. :.
Mb3528c|M.bovis_AF2122/97 PLASTTTDLTELLRNSRRPLQGILENARPLATELD--NRKAEVNNDIEQL
Rv3498c|M.tuberculosis_H37Rv PLASTTTDLTELLRNSRRPLQGILENARPLATELD--NRKAEVNNDIEQL
MUL_4061|M.ulcerans_Agy99 PLASTTTDLTELLKNSRRPLQGLLENARPLATELD--NRKDEVNNDVEQL
MAB_4152c|M.abscessus_ATCC_199 PLASTASSLESVLKDTRPYIKGTIEQARQLATRVD--ERKADVNVVVENL
MSMEG_4793|M.smegmatis_MC2_155 QLDNGTASIATLLTQARPPLDATVDQLNRMAPLLD--DHKVVLDRGLQKA
Mvan_4149|M.vanbaalenii_PYR-1 ALDNGTASIADLLGRGRAPLANTVDEMNRLAPLVD--NDLDRLDATLQRL
MMAR_4709|M.marinum_M ALDNGTTSIADLLGRARAPLAGTVDQLNRLAPLLD--KDKNLIDISLQKL
MAV_0949|M.avium_104 ALDRGTASLADLLAQARPPLTGTIDQLNRLAPILD--NDKDRLDAAIGKA
Mflv_4537|M.gilvum_PYR-GCK ALDSGTASLAGLLTEARPPLAGTVDQLNRLAPLLSNETDLARLDLALQKT
TH_4449|M.thermoresistible__bu ALESGSASLADLLAGVRPPLDGTVDELARLTPLLD--ADKDRIEVALQKA
MLBr_02590|M.leprae_Br4923 HISNAAGTVANLLAEDHALLHKSINYLDGIQQPLI--DQRLQLEDYLHKL
: : : :* : : :: : : :: : .
Mb3528c|M.bovis_AF2122/97 GEDYLRLSA-LGSYGAFFNIYFCSVTIKINGPAGSDILLPIGGQPDPSKG
Rv3498c|M.tuberculosis_H37Rv GEDYLRLSA-LGSYGAFFNIYFCSVTIKINGPAGSDILLPIGGQPDPSKG
MUL_4061|M.ulcerans_Agy99 GEDYLRLAA-LGSYGAFFNIYFCTVTIKINGPAGSDILIPMGGQPDPSKG
MAB_4152c|M.abscessus_ATCC_199 AENYLRLNA-LGAYGSFFNIYYCSIRIKVNGPVGTDWLIPFGGPPDPSKG
MSMEG_4793|M.smegmatis_MC2_155 PANYRKLAR-LGSYGSWIMYYVCGISIRVTDLQGRTAVFPMIKQEG---G
Mvan_4149|M.vanbaalenii_PYR-1 PEIYRKLAR-VGSYGAWFPYYICGISFRASDLEGRTVVFPWIKQEE---G
MMAR_4709|M.marinum_M PDNYRKLTR-LGSYGAWFPYYLCGLALRVSDLQYRTVEVGITHQVT---G
MAV_0949|M.avium_104 PKNYRKLVR-LGANGATIPYYLCMLELRGTDLQGKTVRAPIFRSDA---G
Mflv_4537|M.gilvum_PYR-GCK PQNYRKLVR-LGSYGSWLNLYICGVSIRVSDLQGRTAHFPWVIQNT---G
TH_4449|M.thermoresistible__bu PHNYRKLVR-LGAYGSFINYYFCAATIRVSDLQGRTAVFPWIRNPG---A
MLBr_02590|M.leprae_Br4923 PTVLNQIGRTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQP-TG
:: :*: * . * * :: .. .
Mb3528c|M.bovis_AF2122/97 RCAFAK-
Rv3498c|M.tuberculosis_H37Rv RCAFAK-
MUL_4061|M.ulcerans_Agy99 RCAFAK-
MAB_4152c|M.abscessus_ATCC_199 RCAFKNE
MSMEG_4793|M.smegmatis_MC2_155 RCAEP--
Mvan_4149|M.vanbaalenii_PYR-1 RCVDE--
MMAR_4709|M.marinum_M RCAEPDA
MAV_0949|M.avium_104 RCTEP--
Mflv_4537|M.gilvum_PYR-GCK RCGEP--
TH_4449|M.thermoresistible__bu RCGEP--
MLBr_02590|M.leprae_Br4923 RCTPQ--
**