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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2568 | - | - | 100% (344) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4265 | - | e-123 | 65.58% (337) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4449 | - | e-112 | 60.78% (334) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3528c | mce4B | 4e-68 | 40.90% (335) | MCE-family protein MCE4B |
| M. gilvum PYR-GCK | Mflv_4537 | - | 1e-147 | 75.51% (343) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1967 | mce3B | 3e-70 | 42.90% (338) | MCE-family protein MCE3B |
| M. leprae Br4923 | MLBr_02590 | mce1B | 8e-57 | 36.26% (342) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4152c | - | 3e-68 | 41.12% (338) | MCE-family protein |
| M. marinum M | MMAR_4709 | - | 1e-119 | 64.14% (343) | MCE-family protein |
| M. avium 104 | MAV_0949 | - | 1e-114 | 62.31% (337) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_2856 | - | 1e-164 | 83.09% (343) | virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_4061 | mce4B | 1e-70 | 42.69% (335) | MCE-family protein Mce4B |
| M. vanbaalenii PYR-1 | Mvan_2852 | - | 1e-149 | 76.47% (340) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3528c|M.bovis_AF2122/97 MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFT
MUL_4061|M.ulcerans_Agy99 MASGGMPSHRSMVIKVSVFGVVMLVLAAALVVVFGDFRFGPTNVYHATFT
MAB_4152c|M.abscessus_ATCC_199 -------MKRATQIKVIVFTVVMLLVAAGLIITFGEFRFGSGKRYHAMFS
TH_2568|M.thermoresistible__bu -----MTGIGGTAAKFGIFGTVMLLLTGMLFVIFGEYRSGSTTDYSAVFD
MSMEG_2856|M.smegmatis_MC2_155 -----MTGIGGTALKFGVFGVVMTLMTGVLFVIFGEYRSGSANTYSAVFD
Mflv_4537|M.gilvum_PYR-GCK -----MTDVGKAATKFAAFGLTMVVLTAGLFMIFGEYRSGAANRYSAVFT
Mvan_2852|M.vanbaalenii_PYR-1 --------MGGAATKFAAFGLTMVLLTAGLFVIFGEYRSGSTHGYSAVFA
MMAR_4709|M.marinum_M -----MTGSRAMIIKFGAFAAVMIVLTVFLFFIFGQYRTGSTNGYSALFN
MAV_0949|M.avium_104 -----MR-TRATLIKFAIFAVVMAMLTAFLFFIFGQYRTGATNGYSAVFT
Rv1967|M.tuberculosis_H37Rv ----MRENLGGVVVRLGVFLAVCLLTAFLLIAVFGEVRFGDGKTYYAEFA
MLBr_02590|M.leprae_Br4923 ------MKLTGTVVRLSIFSLVLLLFTVMIIVVFGQMRFGRTNGYTAEFT
:. * . : : :. **: * * * * *
Mb3528c|M.bovis_AF2122/97 DASRLKAGQKVRIAGVPVGSVKAVK-LNPDHSIDVAFAIDRSYTLYSSTR
MUL_4061|M.ulcerans_Agy99 NASRLKAGQKVRIAGVPVGSVKAVD-LNPDNTIDVAFAIDRAYTMYSSTR
MAB_4152c|M.abscessus_ATCC_199 TASDLRSGQKVRIAGVPVGRVKNVS-LNRDNSVEVTFDVDSKYQLYSSSR
TH_2568|M.thermoresistible__bu DVSSLKRGDSVRVAGLRVGTVKDVS-LQQDNTVLVRFTADDKVRLTEGTR
MSMEG_2856|M.smegmatis_MC2_155 DVSSLKPGDSVRVAGLRVGTVNSVA-LQPDNTVVVKFDADDDVRLTEGTT
Mflv_4537|M.gilvum_PYR-GCK DSSSLTSGDSVRAAGIRVGTVRGVT-LQDDNTVVVDFDADDNVRLTEGTR
Mvan_2852|M.vanbaalenii_PYR-1 DSSSLESGDSVRVAGIRIGTVRSVN-LQADNTVVVDFDADDDIRLTESTK
MMAR_4709|M.marinum_M DVSRLKPGETVRIAGVRVGTVNSVS-LRTDKKVLVKFDADRNIVLTTGTR
MAV_0949|M.avium_104 DVSRLKPGQSVRVAGIRVGTVNSVS-LQPDKKVVVKFDADRNIVLTEGTR
Rv1967|M.tuberculosis_H37Rv NVSNLRTGKLVRIAGVEVGKVTRIS-INPDATVRVQFTADNSVTLTRGTR
MLBr_02590|M.leprae_Br4923 NISGLRTGQFVRASGVEVGKVNSVALINGGTRVRVKFNVDRSVPLYQSTT
* * *. ** :*: :* * : :. . : * * * : .:
Mb3528c|M.bovis_AF2122/97 AVIRYENLVGDRFLEITSGPG--ELRKLPPGGTINVAHTQPALDLDALLG
MUL_4061|M.ulcerans_Agy99 AVIRYENLVGDRYLEITSGPD--ELRKLPPGGTINAEHTQPALDLDALLG
MAB_4152c|M.abscessus_ATCC_199 AIIRYENLVGDRYLEITAGPG--ELHKLPDGGTLDKEHTQPALDLDALLG
TH_2568|M.thermoresistible__bu AKVRYLNLVGDRYLELVDEPG--STRIQPPGSLIGSDRTEPALDLDLLLG
MSMEG_2856|M.smegmatis_MC2_155 VKVRYLNLVGDHYLELVDEPG--SARIQPPGSQIGSDRTESALDLDLLLG
Mflv_4537|M.gilvum_PYR-GCK IAVRYLNLVGDRYLELLDEPG--SARIQPSGSRIGLERTEPALNLDLLLG
Mvan_2852|M.vanbaalenii_PYR-1 VAVRYLNLVGDRYLELLDAPG--STKLQRPGSRIGVERTEPALNLDLLLG
MMAR_4709|M.marinum_M AVVRYLNLVGDRYLELVDGPG--STKTLPAGSQIPIERTAGALDLDLLLG
MAV_0949|M.avium_104 AAVRYLNLVGDRYLELVDGPG--SPKRLPAGGQIPVSRTAPALDLDLLLG
Rv1967|M.tuberculosis_H37Rv AVIRYDNLFGDRYLALEEGAG--GLAVLRPGHTIPLARTQPALDLDALIG
MLBr_02590|M.leprae_Br4923 AQIRYLDLIGNRYLELKHGEGQGSEKIMPAGGLIPLSRTSPALDLDALIG
:** :*.*:::* : . * : :* **:** *:*
Mb3528c|M.bovis_AF2122/97 GLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARD
MUL_4061|M.ulcerans_Agy99 GLRPVLKGLDADKVNTVTGAVIELLQGQGGALANVLADTSAFSTALARRD
MAB_4152c|M.abscessus_ATCC_199 GLRPVLKGFDAAKVNEISNAFIQILQGQGGTLSQLLGDTSSFTSGLAERD
TH_2568|M.thermoresistible__bu GLKPVIQGLNPQDVNALTGALIQALQGQGGDIESLFSHTSSFTNTLADNG
MSMEG_2856|M.smegmatis_MC2_155 GLKPVIQGLNPQDINALTSSLIQILQGQSGDVEALFARTSAFTNTLADNG
Mflv_4537|M.gilvum_PYR-GCK GLKPVIQGLNPDDVNALTSSLIQILQGQGGNLESLFSRTSSFTNSLADNG
Mvan_2852|M.vanbaalenii_PYR-1 GLKPVIQGLNPDDVNALTSSLIQILQGQGGNLESLFARTASFTNALADNG
MMAR_4709|M.marinum_M GLKPVTQGLNPQDVNALSASLIQIFQGEGSTLESLLSKTSSFTNALADNN
MAV_0949|M.avium_104 GLKPVTQGLNARDVNALTSGLLQVFQGQGGTLDSLFTKATSFSNALADND
Rv1967|M.tuberculosis_H37Rv GFKPLFRALNPEQVNALSEQLLHAFAGQGPTIGSLLAQSAAVTNTLADRD
MLBr_02590|M.leprae_Br4923 GFKPLFRALDPDKINTIASAIVAAFQGQGGTINDILDQTAQLTTAIGERD
*::*: :.::. .:* :: .: : *:. : :: : .: :. ..
Mb3528c|M.bovis_AF2122/97 QLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAIS
MUL_4061|M.ulcerans_Agy99 QLIGDTITNLNSVLATVDQRSAQFSASVDQLQQLITGLAENKDVIAGAIP
MAB_4152c|M.abscessus_ATCC_199 QLIGDVINHLNEVLATVDSKSTQFSSSVDQLQQLISGLAQQRDVVAGALP
TH_2568|M.thermoresistible__bu RVVEQLIDNLNEVLNTIAEDGDKFSGAVNHLENLITRLAADRDPIGEAIT
MSMEG_2856|M.smegmatis_MC2_155 QTVEQLIVNLNDVLTTVARDGEKFSGAVDHLETLVTGLAADRDPIAEAIT
Mflv_4537|M.gilvum_PYR-GCK QTVERLIDTLNETLATVSADGQNLSSAIDQLEQLATGLAQDRDPIGDAIT
Mvan_2852|M.vanbaalenii_PYR-1 QTVERLIETLNETIGTVAADGEKFSGAIDQLEQLATGLAQDRDPIGEAIT
MMAR_4709|M.marinum_M ETVQALIDNLNVVVDTVNREGTKFSGAIDRLERLISALSQDRDTIGAAIT
MAV_0949|M.avium_104 QTVQQLIDNLNIVIGTISKDGKQFSGAVDRLERLVSGLSDDRNTIGSAID
Rv1967|M.tuberculosis_H37Rv RLIGQVITNLNVVLGSLGAHTDRLDQAVTSLSALIHRLAQRKTDISNAVA
MLBr_02590|M.leprae_Br4923 QAIGEVVKNLNVVLDTTVRHRKEFDQTVNNLEILITGLKDHGDQLAGSFA
. : : ** .: : .:. :: *. * * :. :.
Mb3528c|M.bovis_AF2122/97 PLASTTTDLTELLRNSRRPLQGILENARPLATELDNRKAE--VNNDIEQL
MUL_4061|M.ulcerans_Agy99 PLASTTTDLTELLKNSRRPLQGLLENARPLATELDNRKDE--VNNDVEQL
MAB_4152c|M.abscessus_ATCC_199 PLASTASSLESVLKDTRPYIKGTIEQARQLATRVDERKAD--VNVVVENL
TH_2568|M.thermoresistible__bu ALDNGTASLADLLGRSRPPLAGTVDELARLAPLLSNDTDLARIDLALQKT
MSMEG_2856|M.smegmatis_MC2_155 ALDNGTASLASLLTEARPPLSGTVDQMERLAPLLSNDDDLARLDLALQKT
Mflv_4537|M.gilvum_PYR-GCK ALDSGTASLAGLLTEARPPLAGTVDQLNRLAPLLSNETDLARLDLALQKT
Mvan_2852|M.vanbaalenii_PYR-1 ALDNGTASLAGLLTEARPPLAGTVDQLNRLAPLLSNETDLARLDLALQKT
MMAR_4709|M.marinum_M ALDNGTTSIADLLGRARAPLAGTVDQLNRLAPLLDKDKNL--IDISLQKL
MAV_0949|M.avium_104 ALDRGTASLADLLAQARPPLTGTIDQLNRLAPILDNDKDR--LDAAIGKA
Rv1967|M.tuberculosis_H37Rv YTNAAAGSVADLLSQARAPLAKVVRETDRVAGIAAADHDY--LDNLLNTL
MLBr_02590|M.leprae_Br4923 HISNAAGTVANLLAEDHALLHKSINYLDGIQQPLIDQRLQ--LEDYLHKL
: : :* : : : : :: :
Mb3528c|M.bovis_AF2122/97 GEDYLRLSA-LGSYGAFFNIYFCSVTIKINGP--AGSDILLPIGGQPDPS
MUL_4061|M.ulcerans_Agy99 GEDYLRLAA-LGSYGAFFNIYFCTVTIKINGP--AGSDILIPMGGQPDPS
MAB_4152c|M.abscessus_ATCC_199 AENYLRLNA-LGAYGSFFNIYYCSIRIKVNGP--VGTDWLIPFGGPPDPS
TH_2568|M.thermoresistible__bu PANYRKLVR-LGAYGSWLNLYICGVSVRVTDL--QGRTAHFPWVIQ---N
MSMEG_2856|M.smegmatis_MC2_155 PANYRKLVR-LGSYGSWLNLYICGVSVRVTDL--QGRTAHFPWVIQ---N
Mflv_4537|M.gilvum_PYR-GCK PQNYRKLVR-LGSYGSWLNLYICGVSIRVSDL--QGRTAHFPWVIQ---N
Mvan_2852|M.vanbaalenii_PYR-1 PQNYRKLVR-LGSYGSWLNLYICGVSIRVSDL--QGRTAHFPWVIQ---N
MMAR_4709|M.marinum_M PDNYRKLTR-LGSYGAWFPYYLCGLALRVSDL--QYRTVEVGITHQ---V
MAV_0949|M.avium_104 PKNYRKLVR-LGANGATIPYYLCMLELRGTDL--QGKTVRAPIFRS---D
Rv1967|M.tuberculosis_H37Rv PDKYQALVR-QGMYGDFFAFYLCDVVLKVNGK--GGQPVYIKLAGQ---D
MLBr_02590|M.leprae_Br4923 PTVLNQIGRTIGSYGDFVNFYSCDITLKINGLQPGGPVRTVRLFQQ---P
: * * . * * : :: ..
Mb3528c|M.bovis_AF2122/97 KGRCAFAK-
MUL_4061|M.ulcerans_Agy99 KGRCAFAK-
MAB_4152c|M.abscessus_ATCC_199 KGRCAFKNE
TH_2568|M.thermoresistible__bu TGRCAEP--
MSMEG_2856|M.smegmatis_MC2_155 TGRCAEP--
Mflv_4537|M.gilvum_PYR-GCK TGRCGEP--
Mvan_2852|M.vanbaalenii_PYR-1 TGRCAEP--
MMAR_4709|M.marinum_M TGRCAEPDA
MAV_0949|M.avium_104 AGRCTEP--
Rv1967|M.tuberculosis_H37Rv SGRCAPK--
MLBr_02590|M.leprae_Br4923 TGRCTPQ--
***