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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4203 | - | - | 100% (417) | sensor histidine kinase |
| M. thermoresistible (build 8) | TH_1533 | - | 2e-20 | 30.00% (210) | two-component system sensor kinase |
| M. thermoresistible (build 8) | TH_0388 | - | 1e-11 | 26.02% (269) | TWO COMPONENT SENSOR HISTIDINE KINASE DEVS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0868 | - | 2e-14 | 29.91% (234) | two component sensor kinase |
| M. gilvum PYR-GCK | Mflv_5015 | - | 0.0 | 82.84% (402) | GAF sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv0845 | - | 7e-14 | 31.31% (214) | two component sensor kinase |
| M. leprae Br4923 | MLBr_00774 | mtrB | 9e-05 | 24.66% (219) | putative two-component system sensor kinase |
| M. abscessus ATCC 19977 | MAB_0061 | - | 1e-20 | 34.06% (229) | two component sensor kinase |
| M. marinum M | MMAR_4781 | - | 3e-16 | 30.34% (234) | two-component sensor kinase |
| M. avium 104 | MAV_0874 | - | 1e-18 | 31.20% (234) | hypothetical protein MAV_0874 |
| M. smegmatis MC2 155 | MSMEG_1493 | - | 0.0 | 84.90% (404) | sensor histidine kinase |
| M. ulcerans Agy99 | MUL_0350 | - | 2e-16 | 30.34% (234) | two component sensor kinase |
| M. vanbaalenii PYR-1 | Mvan_1357 | - | 0.0 | 83.87% (403) | GAF sensor signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5015|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1357|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1493|M.smegmatis_MC2_155 ------------------------------------------------MN
TH_4203|M.thermoresistible__bu ---------------------------------------------VTSGP
Mb0868|M.bovis_AF2122/97 ----------------------------------------MPSYGNLGRL
Rv0845|M.tuberculosis_H37Rv ----------------------------------------MPSYGNLGRL
MMAR_4781|M.marinum_M --------------------------------------------------
MUL_0350|M.ulcerans_Agy99 --MMNSRQREADRRQFAPSCRRQDESAGQSLGQRRTERSPNPSCANYGQL
MAV_0874|M.avium_104 --------------------------------------------------
MAB_0061|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00774|M.leprae_Br4923 MIFSSRRRIRGRWGRSGPMMRGMGALTRVVGVVWRRSLQLRVVALTFGLS
Mflv_5015|M.gilvum_PYR-GCK -------MTRPLLTADRELALLRELIQAASSGPG----VEPLAAASARMI
Mvan_1357|M.vanbaalenii_PYR-1 -------MSRPLLTADRELALLRELIQAASSGPG----VEPLAAAAARMI
MSMEG_1493|M.smegmatis_MC2_155 AAKRAVKPVRDLVDADRELALLRELIQAASSGPG----VEPLAAAAARMI
TH_4203|M.thermoresistible__bu HPDPVRDLSEQLLTADRELVLLRELIQAASRGPG----VEPLAAAAARMI
Mb0868|M.bovis_AF2122/97 GG-RHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMV
Rv0845|M.tuberculosis_H37Rv GG-RHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMV
MMAR_4781|M.marinum_M -----------MVTSDAELARVRRTHQLRAYRIGSVLRIGVVLFMVAAML
MUL_0350|M.ulcerans_Agy99 VGSCRLYGVPVVVTSDAELARVRRTHQLRAYRIGSVLRIGVVLFMVAAML
MAV_0874|M.avium_104 ----------MAVAGDAELERVRAVHQMRSYRIGSVLRVGVVGLMVAAMI
MAB_0061|M.abscessus_ATCC_1997 ---------------MTRLDNMADYFAAEPMRVSAWLRLPLIG--LIVLL
MLBr_00774|M.leprae_Br4923 LAVILALGFVLTSQLTSRVLDVKVRVAIEQIERARTTVTGIVNGEETRSL
.: : . : :
Mflv_5015|M.gilvum_PYR-GCK TA---------STDSDVCFVHVLDDTERSLTLAGATPPFDSEVGKIRLPL
Mvan_1357|M.vanbaalenii_PYR-1 TA---------ATDSDVCFVHVLDDTERSLTLAGATPPFDSEVGKIRLPL
MSMEG_1493|M.smegmatis_MC2_155 TA---------ATGTDVCFVHVLDDSDRSLTLAGATPPFDSEVGKIRLPI
TH_4203|M.thermoresistible__bu TA---------ATASDVCFVHVLDDTERSLTLAGATPPFDKEVGKIRLPL
Mb0868|M.bovis_AF2122/97 VG---------TSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRR
Rv0845|M.tuberculosis_H37Rv VG---------TSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRR
MMAR_4781|M.marinum_M VG---------TPRREWGAQTALICVYAFAALWALALAFRRSRPMVSLDR
MUL_0350|M.ulcerans_Agy99 VG---------TPRREWGAQTALICVYAFAALWALALAFRRSRPMVSLDR
MAV_0874|M.avium_104 IG---------TARSEWPQESVLILLYGIIALGAVALAFAPFRRWIGIGR
MAB_0061|M.abscessus_ATCC_1997 GS---------DPNIQMWHNGVYYGVLAAYTLSAVVWVGIAVRGQVADWV
MLBr_00774|M.leprae_Br4923 DSSLQLARNTLTSKTDPTSGAGLVGAFDAVLIVPGDGPRTATTAGPVDQV
. . : :
Mflv_5015|M.gilvum_PYR-GCK GQGIS-----GWVASHRQ---------PVVIRRDKESDPRY-----LPFQ
Mvan_1357|M.vanbaalenii_PYR-1 GQGIS-----GWVASNRE---------PVVIRRDKESDPRY-----LPFR
MSMEG_1493|M.smegmatis_MC2_155 GQGIS-----GWVADHCE---------PVVISHDKEADPRY-----MPFE
TH_4203|M.thermoresistible__bu GQGIS-----GWVASHRE---------PVVITENKEADPRY-----LPFQ
Mb0868|M.bovis_AF2122/97 FRSMGRLEPFAFTAVDVL---------ILTGFQLLSTDGIYPLLIMILLP
Rv0845|M.tuberculosis_H37Rv FRSMGRLEPFAFTAVDVL---------ILTGFQLLSTDGIYPLLIMILLP
MMAR_4781|M.marinum_M FANIARYEPLAFTAVDVL---------ALTGFQLLSTDGIYSLLIMTLLP
MUL_0350|M.ulcerans_Agy99 FANIARYEPLAFTAVDVL---------ALTGFQLLSTDGIYSLLIMTLLP
MAV_0874|M.avium_104 LAGVGRLEPFAFTVVDIL---------ALTIFQLLSTNGIYPLLIMAMLP
MAB_0061|M.abscessus_ATCC_1997 APAATS----ADIAAVVM---------LCLASGAGNTELLPVFFLLPVSV
MLBr_00774|M.leprae_Br4923 PNSLRGFIKAGQAAYQYATVHTEGFSGPALIIGTPTSSQVTNLELYLIFP
. . :.
Mflv_5015|M.gilvum_PYR-GCK SLRGRDFTS-MVSVPMETDPGGLVGVLNVHTVAERDFTDRDVELLLVIGR
Mvan_1357|M.vanbaalenii_PYR-1 SLRGRDFTS-MVSVPMETDPGGLVGVLNVHTVAERDFGDRDVGLLLVIGR
MSMEG_1493|M.smegmatis_MC2_155 SLRGRDFTS-MVSVPMEAEPGGLVGVLNVHTVRRREFTPRDVELLVVIGR
TH_4203|M.thermoresistible__bu SLRGRDFTS-MVSVPMETDPGGLVGVLNVHTVERREFTRRDVDLLLVIGR
Mb0868|M.bovis_AF2122/97 VLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYA
Rv0845|M.tuberculosis_H37Rv VLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYA
MMAR_4781|M.marinum_M VLVALDISSRRAAVVLALTLVGFALALAQDPVVIRMNGWPEAIFRFGLYA
MUL_0350|M.ulcerans_Agy99 VLVALDISSRRAAVVLALTLVGFGLALAQDPVVIRMNGWPEAIFRFGLYA
MAV_0874|M.avium_104 VLLGLDVSSRRAAVVLIFSMLGFAIAVLQDPVMSSSVRLPEAGFRFLLYG
MAB_0061|M.abscessus_ATCC_1997 AFQERPAITAILGIITAVAYFGILVYYIADGNLERIPGDEYVTWAALLWL
MLBr_00774|M.leprae_Br4923 LKNEQATVTLVRGTMATGGMVLLVLLSGIALLVSRQVVVPVRSASRIAER
: . :
Mflv_5015|M.gilvum_PYR-GCK LIAG-------AMHQARLHRQLVARERAHENFVEQVIEAQEL--ERRRLA
Mvan_1357|M.vanbaalenii_PYR-1 LIAG-------AMHQARLHRQLVARERAHEHFVEQVIEAQEL--ERRRLA
MSMEG_1493|M.smegmatis_MC2_155 LIAG-------ALHQARLHRQLVARERAHENFVEQVIEAQEL--ERRRLA
TH_4203|M.thermoresistible__bu LIAG-------GLHQARLHRQLVARERAHEIFVEQVIEAQEL--ERRRLA
Mb0868|M.bovis_AF2122/97 FLCATALM--VVRIEERHTRSVAGLSALREELLAQTMTASEV--LQRRIA
Rv0845|M.tuberculosis_H37Rv FLCATALM--VVRIEERHTRSVAGLSALRAELLAQTMTASEV--LQRRIA
MMAR_4781|M.marinum_M FLCATALM--VVRSEERHARSVATLSVIREELLAQTMTASEV--LQRRIS
MUL_0350|M.ulcerans_Agy99 FLCATALM--VVRSEERHARSVATLSVIREELLAQTMTASEV--LQRRIS
MAV_0874|M.avium_104 FLCCAAFL--VVRIEERHTRSVAGLSALREELLAQTMNASDV--SQRRIS
MAB_0061|M.abscessus_ATCC_1997 TVFTTG----MCFVLKRRSARVVQLVHIREQLVLESMRADER--RNREVA
MLBr_00774|M.leprae_Br4923 FAEGHLSERMPVRGEDDMARLAVSFNDMAESLSRQITQLEEFGNLQRRFT
. : : .: .*..:
Mflv_5015|M.gilvum_PYR-GCK GDIHDGISQRLVTLSYRLDAAAQAAKSPADHAALTEQLDRARELADLTLQ
Mvan_1357|M.vanbaalenii_PYR-1 GDIHDGISQRLVTLSYRLDAAAQAATSPGDPDALHEQLDRARELAELTLQ
MSMEG_1493|M.smegmatis_MC2_155 ADIHDGISQRLVTLSYRLDAAARAAD---DPRAVAEQLGKARELADLTLQ
TH_4203|M.thermoresistible__bu ADIHDGISQRLVTLSYRLDAAIRAVD---DPATVTEQLSKARELADLTLE
Mb0868|M.bovis_AF2122/97 EAIHDGPLQDVLAARQELIELDAVTPG-------DERVGRALAGLQSASE
Rv0845|M.tuberculosis_H37Rv EAIHDGPLQDVLAARQELIELDAVTPG-------DERVGRALAGLQSASE
MMAR_4781|M.marinum_M ESIHDGPLQDVLAARQELIELRAAAPH-------DQRVSTALAGLQSASD
MUL_0350|M.ulcerans_Agy99 ESIHDGPLQDVLAARQELIELRAAAPH-------DQRVSTALAGLQSASD
MAV_0874|M.avium_104 EFIHDGPLQDILAVRQELVELDAAVPD-------DERIGRALAGLQLASE
MAB_0061|M.abscessus_ATCC_1997 ERLHDGPLQNLLAARLRIEEVLERQSD--------PVLTAVHSSLRETAA
MLBr_00774|M.leprae_Br4923 SDVSHELRTPLTTVRMAADLIYDHSSD------LDPTLRRSTELMVSELD
: . : : :
Mflv_5015|M.gilvum_PYR-GCK EARAAISGLRPPVLDDLGLAGGLASLARSIPQIGI---------------
Mvan_1357|M.vanbaalenii_PYR-1 EARAAISGLRPPVLDDLGLSGGLASLARTIPQVTI---------------
MSMEG_1493|M.smegmatis_MC2_155 EARAAISGLRPPVLDDLGLSGGLASLARSIPQVDL---------------
TH_4203|M.thermoresistible__bu ETRAAISGLRPPVLDDLGLSGGLASLAQSVGQLDIGV-------------
Mb0868|M.bovis_AF2122/97 RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSG---------------
Rv0845|M.tuberculosis_H37Rv RLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSG---------------
MMAR_4781|M.marinum_M LLRQATFELHPAVLEQVGLGAAVEQLASFHAQRSG---------------
MUL_0350|M.ulcerans_Agy99 LLRQATFELHPAVLEQVGLGAAVEQLASFHAQRSG---------------
MAV_0874|M.avium_104 RLRQATFELHPAVLEQVGLGAAVQQLAEFTAQRSG---------------
MAB_0061|M.abscessus_ATCC_1997 ELRGAVSSLHPQVLIELGLTAAIRELARQHTARGI---------------
MLBr_00774|M.leprae_Br4923 RFETLLNDLLEISRHDAGVAELSVEAVDLRVMVNNALGNVGHLAEEAGIE
. * : *: . .
Mflv_5015|M.gilvum_PYR-GCK --ETDLDDTRLADHIELALYRIAQECLQNVVKHARASAARLTFAVD----
Mvan_1357|M.vanbaalenii_PYR-1 --DVDLVDTRLPDHIELALYRIAQECLQNVVKHARASRARLTFALDRGDH
MSMEG_1493|M.smegmatis_MC2_155 --DVDLADTRVPDHIELALYRIAQECLQNVVKHARATTARLTFAVE----
TH_4203|M.thermoresistible__bu DIEVDLAETRLPDHIELALYRIAQECLQNVVKHARARTARLTYAVDRGEH
Mb0868|M.bovis_AF2122/97 IKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGIT----
Rv0845|M.tuberculosis_H37Rv IKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGIT----
MMAR_4781|M.marinum_M IRITDDVDYPIRDEIDPIVFGVARELLSNVVQHSRARNASVALGIS----
MUL_0350|M.ulcerans_Agy99 IRITDDVDYPIRDEIDPIVFGVARELLSNVVQHSRARNASVALGIS----
MAV_0874|M.avium_104 IEISTDIDYSGRSAIDAVVFGVVRELLSNVVQHSRARTAAIMLGRT----
MAB_0061|M.abscessus_ATCC_1997 VDVSTAVEEVGSPPAQPLVYRAAKELLTNAVKHGRAKNIRVELSSR----
MLBr_00774|M.leprae_Br4923 LLVDMPVDEVIAEVDARRVERILRNLIANAIDHSEHKPVRIRMAAD----
: : :: : *.: *. : .
Mflv_5015|M.gilvum_PYR-GCK DNTARLEIADDGVGFD-------------TFEHPLGSDEMGGYGLLSMAE
Mvan_1357|M.vanbaalenii_PYR-1 GDLARLEIADDGIGFD-------------TLEHPLGGDEMGGYGLLSMAE
MSMEG_1493|M.smegmatis_MC2_155 DGIARLEIVDDGIGFD-------------TFEHPLGSDEMSGYGLLSMAE
TH_4203|M.thermoresistible__bu GEVARLEIVDDGVGFD-------------TFEHPLGGDDMSGYGLLSMAE
Mb0868|M.bovis_AF2122/97 DEKCVLDVADDGVGVTG-----------DTMARRLG---EGHIGLASHRA
Rv0845|M.tuberculosis_H37Rv DEKCVLDVADDGVGVTG-----------DTMARRLG---EGHIGLASHRA
MMAR_4781|M.marinum_M DGVCVLDVADDGVGVSG-----------ETMARRLG---QGHIGLASHRA
MUL_0350|M.ulcerans_Agy99 DGVCVLDVADDGVGVSG-----------ETMARRLG---QGHIGLASHRA
MAV_0874|M.avium_104 DGTCVLHVVDDGVGFNQ-----------ETVARRLG---EGHIGLASHRA
MAB_0061|M.abscessus_ATCC_1997 RCWLTLVVTDDGRGFDP-----------RDLVLSVA---DGHIGLASLTV
MLBr_00774|M.leprae_Br4923 EDTVAVTVRDYGIGLRPGEEKLVFSRFWRSDPSRVRRSGGTGLGLAISIE
: : * * *. : **
Mflv_5015|M.gilvum_PYR-GCK RAEIVGGRLNIRSRPGSGTTVTATIPLHQGGA------------------
Mvan_1357|M.vanbaalenii_PYR-1 RAEIVGGRLNIRSRPGAGTTVTATIPLPANRE------------------
MSMEG_1493|M.smegmatis_MC2_155 RAEIVGGRLNIRSRPGAGTAVTATIPLPSHEPAPNLTKLP----------
TH_4203|M.thermoresistible__bu RAEIVGGRLNIRSRPGAGTAVIATIPLPPATR------------------
Mb0868|M.bovis_AF2122/97 RVDAAGGVLVFLATP-RGTHVCVELPLKR---------------------
Rv0845|M.tuberculosis_H37Rv RVDAAGGVLVFLATP-RGTHVCVELPLKR---------------------
MMAR_4781|M.marinum_M RVDAAGGSLVFLNTP-TGTHVCVRIPLKG---------------------
MUL_0350|M.ulcerans_Agy99 RVDAAGGSLVFLNTP-TGTHVCVRIPLKG---------------------
MAV_0874|M.avium_104 RVEAAGGELVFLDVP-VGTHVCVEVPLRN---------------------
MAB_0061|M.abscessus_ATCC_1997 PIEAAGGAVTITSAPGAGTRVSVTAPADMAA-------------------
MLBr_00774|M.leprae_Br4923 DARLHQGRLEAWGEPGQGACFRLTLPLVRGHKVTTSPLPMKPILQPSPQA
* : * *: . *
Mflv_5015|M.gilvum_PYR-GCK ----------------------
Mvan_1357|M.vanbaalenii_PYR-1 ----------------------
MSMEG_1493|M.smegmatis_MC2_155 ----------------------
TH_4203|M.thermoresistible__bu ----------------------
Mb0868|M.bovis_AF2122/97 ----------------------
Rv0845|M.tuberculosis_H37Rv ----------------------
MMAR_4781|M.marinum_M ----------------------
MUL_0350|M.ulcerans_Agy99 ----------------------
MAV_0874|M.avium_104 ----------------------
MAB_0061|M.abscessus_ATCC_1997 ----------------------
MLBr_00774|M.leprae_Br4923 STAGQQHGTQRQRLREHAERSR