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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4174 | - | - | 100% (442) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2690 | - | e-136 | 56.97% (423) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3624 | - | e-131 | 55.75% (409) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0604 | mce2A | 5e-55 | 35.49% (355) | MCE-family protein MCE2A |
| M. gilvum PYR-GCK | Mflv_2101 | - | 1e-133 | 56.21% (443) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1966 | mce3A | 1e-133 | 58.25% (412) | MCE-family protein MCE3A |
| M. leprae Br4923 | MLBr_02589 | mce1A | 6e-52 | 31.73% (394) | putative cell invasion protein |
| M. abscessus ATCC 19977 | MAB_4153c | - | 6e-52 | 35.96% (356) | MCE-family protein |
| M. marinum M | MMAR_2882 | mce3A | 1e-132 | 53.72% (443) | MCE-family protein Mce3A |
| M. avium 104 | MAV_2061 | - | 1e-116 | 50.88% (399) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_0346 | - | 1e-130 | 53.71% (445) | virulence factor |
| M. ulcerans Agy99 | MUL_3918 | mce3A_1 | 1e-129 | 54.46% (437) | MCE-family protein Mce3A_1 |
| M. vanbaalenii PYR-1 | Mvan_4399 | - | 1e-141 | 56.25% (448) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4174|M.thermoresistible__bu ---------------------LGWWAAIMITVVAGMVFVCSTLFAGTFRR
Mvan_4399|M.vanbaalenii_PYR-1 ----------MNHYQGHRKVRPAWWSLALCAALALIIFICWSLFAGTFRS
Mflv_2101|M.gilvum_PYR-GCK ----------MDD----DGLKPGWWTLILVAVFAVAIFVTYALFTGSLKS
MUL_3918|M.ulcerans_Agy99 ----------MDDRK--EGLHPAWHTLILVLLFVAAMWVTYALFMGSLRS
MSMEG_0346|M.smegmatis_MC2_155 ----------MQPRFRDARIKPAWWTWILIAALGVFFFTTGSLFAGTFRS
Rv1966|M.tuberculosis_H37Rv ----------MRRGPGRHRLHDAWWTLILFAVIGVAVLVTAVSFTGSLRS
MMAR_2882|M.marinum_M ----------MGRGPGKHRLHDAWWTVILFAAIVAAILVTTVSFTGTLRP
MAV_2061|M.avium_104 MSKQSSSGLIRRGGNQRNGIDPIWWAPTLFIVIGGLVALTAASFSGKFQT
Mb0604|M.bovis_AF2122/97 --------MPTLVTRKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTP
MLBr_02589|M.leprae_Br4923 -------MTSSTKINASRKPPYKLAGVGLLVVAVVIFGLVYGQFRGNFTP
MAB_4153c|M.abscessus_ATCC_199 ------------MSDTSTRRAVRLAGTVLASVLVLLTVLTYLAYNDAFAD
: : . :
TH_4174|M.thermoresistible__bu YVPVSLTADRTGLVLEKGAKVRMRGVDVGRVGAIEG----GAAPVRLELE
Mvan_4399|M.vanbaalenii_PYR-1 YVPVTLTSERSGLVMEPGAKVKLRGVEVGRVGDIRH----GAQAASLQLQ
Mflv_2101|M.gilvum_PYR-GCK TVPVTLTSDRAGLVMETNAKVKLRGVQVGRVSDISVTGR-QDPTVALQLE
MUL_3918|M.ulcerans_Agy99 VVPVTLTSERSGLVMETNAKVKLRGVQVGRVASIVGGGK-GATPVALTLE
MSMEG_0346|M.smegmatis_MC2_155 FVPVTLVSDRSGLVMETGAKVKLNGVEVGRVSEIRGGAS-G---VSLQLE
Rv1966|M.tuberculosis_H37Rv TVPVTLAADRSGLVMDSGAKVMMRGVQVGRVAQIGRIEW-AQNGASLRLE
MMAR_2882|M.marinum_M HVAVTLTSERSGLVMDAGAKVMLRGVQVGRVRQID-----SNHGASLELE
MAV_2061|M.avium_104 FVPLTLVSDRAGLVMEDGAKVKLRGVQIGQVASIGT----DVKTARLQLK
Mb0604|M.bovis_AF2122/97 KTELTMVASRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLD
MLBr_02589|M.leprae_Br4923 KSKLTMLADRAGLVMDRGSKITYNGVKIGRVADISETVRNGRPVAEFTLD
MAB_4153c|M.abscessus_ATCC_199 TKPITVVSPRAGLVMEEGGKVKFHGLQIGKVTSISYAN----DQAKLELA
::: : *:***:: ..*: .*:.:*:* * . : *
TH_4174|M.thermoresistible__bu IFPDKLSFIPSNVEAEIKATTAFGAKYVELIPPPAPSQARLAAGMTVHSR
Mvan_4399|M.vanbaalenii_PYR-1 IFPDQISHIPANVEAQVRATTIFGAKYVDLVYPEQPSGQRLAAGAELVSR
Mflv_2101|M.gilvum_PYR-GCK IDPDQVQYIPANVEAQIRATTIFGAKFVDLVFPDDPSNQRLEAGQVLQSR
MUL_3918|M.ulcerans_Agy99 IDSDQIRYIPANVQAEIRATTVFGAKFVDLIYPEDPSPQRLKAGQVLMSR
MSMEG_0346|M.smegmatis_MC2_155 IEPDQIRFIPANVEARITATTAFGAKYVDLSYPDNPTGQHLAAGAVLRSR
Rv1966|M.tuberculosis_H37Rv IDPDQIRYIPANVEAQISATTAFGAKFVDLVMPQNPSRARLSAGAVLHSK
MMAR_2882|M.marinum_M IDPDQIRYIPANVEAQISATTAFGAKFVDLVIPPTPSRARLAAGAVLHSK
MAV_2061|M.avium_104 IQPGPFRYLPSNLEAEIKSTTAFGSKFVDLIVPERPSASPLKPGAVLRSR
Mb0604|M.bovis_AF2122/97 VNPRYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVG
MLBr_02589|M.leprae_Br4923 VYPRYLSLIPANVNADIKATTVFGGKYVSLTTPEHPSQKRLTPQTVIDAR
MAB_4153c|M.abscessus_ATCC_199 VNAKDLRLIPSNATVRIAGTTVFGAKSVEFLAPQKPSDSSLRPGATVTAE
: . . :* * . : .:* ** * * : * * : . :
TH_4174|M.thermoresistible__bu NVATEVNTVFQNLVAVLDQIDVAKLNATLSALADGVRGRGESIGQATTAV
Mvan_4399|M.vanbaalenii_PYR-1 NVSIEVNTVFDNLVHLLEHIDPAKLNAVLNAWAEAVRGRGERIGEAITAS
Mflv_2101|M.gilvum_PYR-GCK NVTTEVNTVFQNLVAVLDQVDAAKLNSTLSALADGVRGQGERIGRATTDA
MUL_3918|M.ulcerans_Agy99 NVTSEANTVFQNLVAVLDQIDPAKLNAALSALAEGLRGQGPLIGQATTDA
MSMEG_0346|M.smegmatis_MC2_155 NVSTEVNTVFENLTDVLKMVDPAKLNAVLSALAEGFRGQGERMGQAITDA
Rv1966|M.tuberculosis_H37Rv NVSTEINTVFENVVDLLNMIDPLKLNAVLTAVADAVRGQGERIGQATTDL
MMAR_2882|M.marinum_M NVSTEINTVFENVVDLLNMIDPLKLNAVLSAVAEGVRGQGERIGQATTDL
MAV_2061|M.avium_104 NVTVEVNTVFENLQAVVQALDPAKLNAILSAFAQSVRGKGERIGEAITDA
Mb0604|M.bovis_AF2122/97 SVTTEFNTLFETITSIAEKVDPIELNATLSAVAQAPDGLGGKFGESIVNG
MLBr_02589|M.leprae_Br4923 SVTTEINTLFQTITLIAEKVDPIKLNLTLSAAAQSLAGLGERFGQSIVNG
MAB_4153c|M.abscessus_ATCC_199 AVALEVNTVFENLTRLLGKIDPVNLNATLTAVGEGLRGNGDNFGQGLVEL
*: * **:*:.: : :* :** *.* .:. * * :*.. .
TH_4174|M.thermoresistible__bu SETLRQLNVRIDSMAQGWRSFKGFTDAYGMAAEDILAILDAAATTADTVE
Mvan_4399|M.vanbaalenii_PYR-1 NQVLASVNPLMPTVQRDWQSLQGFADTYAEAAPDILDILQGASTTSATIT
Mflv_2101|M.gilvum_PYR-GCK NQVLLALNPRNETITEDLRALDQFNQTYSAAAQNILATLDAASTTSTTVV
MUL_3918|M.ulcerans_Agy99 NQVLLELNPRYETVTADLRAVKDFNDTFSAAAQDILDTLNALSTTSTTIT
MSMEG_0346|M.smegmatis_MC2_155 NEVLMAINPRQDTIREDWRAMGEVSAAYDHAADDIVKILDAGTTTAETVT
Rv1966|M.tuberculosis_H37Rv NEVLEALNARGDTIGGNWRSLKNFTDTYDAAAQDILTILNAASTTSATVV
MMAR_2882|M.marinum_M NQVLQALNARRDTLRQNWRSLRDFSNTYDAAARDILTILDAASTTSTTVV
MAV_2061|M.avium_104 NSLLRTVNSRMDTIGEDWRLFGATTAVYSDAAQHILSILDSASTTSNTIT
Mb0604|M.bovis_AF2122/97 NQILAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLT
MLBr_02589|M.leprae_Br4923 NSVLDDVNSQLPQARHDIQQLASLGDTYANSASDFFDFLNNSIVTSRTIN
MAB_4153c|M.abscessus_ATCC_199 DQYLDQLNPKLPALQQDFRQAGQVGQIYGDAAPDIVRILDNLPALSRTVV
.. * :* . : : :: .: *: . : *:
TH_4174|M.thermoresistible__bu ARSSQLDALLLSTIGMANIGTELLGSTRDDFVTAVNEARPTTDLLLKYDP
Mvan_4399|M.vanbaalenii_PYR-1 SHADDLDRLLLSTMGFSQTGTDLLSSTRDSFPEAVNILAPTTALLLKYSP
Mflv_2101|M.gilvum_PYR-GCK NQAKELDALLLAAIGLSNSGIDLLAPNQANLIKAVNTLAPTTNLLHKYSP
MUL_3918|M.ulcerans_Agy99 GHSTQLDALLLATIGLSNTGISLLAPNQANLIKAINALEPTTNLLYKYSP
MSMEG_0346|M.smegmatis_MC2_155 SHRSELDTLLLNVIGFGRAGVDLLAPSFTNLVNAVNGFAPTSDLLMKYQP
Rv1966|M.tuberculosis_H37Rv NHSTQLDALLLNAIGLSNAGTNLLGSSRDNLVGAADILAPTTSLLFKYNP
MMAR_2882|M.marinum_M DHARSLDSLLLNVIGLADTGTNLLANNRESLTTSINILEPTTNLLFKYNP
MAV_2061|M.avium_104 DNQRSLDSLLLSAVGFSQTGINVIGANESNIVRAMNLLDPTIALMQKYSP
Mb0604|M.bovis_AF2122/97 SQQRDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSP
MLBr_02589|M.leprae_Br4923 QQQKDLDQVLLAAVGFGNTGADIFSRSGPYLARGAADLVPTAQLLDTYSP
MAB_4153c|M.abscessus_ATCC_199 DQQQDLKATLLAAIGLGNNGYETLAPAEKDLTAALQRLRAPATLLGRYSP
. .*. ** . * . * . :. : . .. *: *.*
TH_4174|M.thermoresistible__bu VYTCLLVGAKLYLDKGGYDALGG-NGRT----------------------
Mvan_4399|M.vanbaalenii_PYR-1 EYTCLLQGAKLALDRGWYDAAGG-NGKS----------------------
Mflv_2101|M.gilvum_PYR-GCK SYTCLLLGAKHLLDEGGYEAPGG-NGRT----------------------
MUL_3918|M.ulcerans_Agy99 EYTCLLEGAKYLLDHGGYEAPGG-NGRS----------------------
MSMEG_0346|M.smegmatis_MC2_155 EYTCLLDGSVSLLQNGHVDAFGG-NGRS----------------------
Rv1966|M.tuberculosis_H37Rv EYTCFLQGAKWYLDNGGYAAWGGADGRT----------------------
MMAR_2882|M.marinum_M EYTCLLQGTKWYLDNGGYAAWGGADGRT----------------------
MAV_2061|M.avium_104 TYTCLFQGAQWYVDHGGRDALGG-NGYS----------------------
Mb0604|M.bovis_AF2122/97 ELFCMIRNFHDAAPKVADAVGGNGYS------------------------
MLBr_02589|M.leprae_Br4923 AIFCTLRNYHDIEPKVTSFLGGNGYSINDHVELLSGLGFLLNPTSAISII
MAB_4153c|M.abscessus_ATCC_199 EIPCTLQAISKALVTFTPLIGGVRPG------------------------
* : * .
TH_4174|M.thermoresistible__bu ------------LVADTTLLFGDDPYRYPEHLPIHNAKGGP--GGKPGCG
Mvan_4399|M.vanbaalenii_PYR-1 ------------IVLDAGLTWATDPYRYPDHLPKVAATGGA--DGKPGCG
Mflv_2101|M.gilvum_PYR-GCK ------------LVLDTSLSFGDDPYQYPRHLPIIGAKGGP--GGKPGCG
MUL_3918|M.ulcerans_Agy99 ------------LVLDAALALGDDPYRFPDNLPIIGAKGGP--GGKPGCG
MSMEG_0346|M.smegmatis_MC2_155 ------------AIFDIGLLLGNDPYHYPDDLPIVGAKGGP--GGKPGCG
Rv1966|M.tuberculosis_H37Rv ------------LQLDVALLFGNDPYVYPDNLPVVAAKGGP--GGRPGCG
MMAR_2882|M.marinum_M ------------LQLDVALLLGNDPYVFPDNLPLVAARGGP--GGAPGCG
MAV_2061|M.avium_104 ------------VILDAALLFGDDPYRYPKHLPKVNATGGP--GGRPSCG
Mb0604|M.bovis_AF2122/97 ------------LAAAGTILGAPNPYVYPDNLPRVNAHGGP--GGRPGCW
MLBr_02589|M.leprae_Br4923 GAGVLSQGLLAPLGLAGVVNGAANPYIYPENLPRVNARGGP--GGAPGCW
MAB_4153c|M.abscessus_ATCC_199 ------------LFLTNSFPLGAPVYTYPDSLPIVNASGGPNCRGLPNIP
. . * :* ** * **. * *.
TH_4174|M.thermoresistible__bu SLPDVEQNFPVRKLVTDTGFGSG-TDIRTNPGIGHPWFINFFPATRAVPE
Mvan_4399|M.vanbaalenii_PYR-1 SLPDVSKNWPVRHLVTDTGYGTG-LDLRPNPGIAHPWWGNFLPVTRAVPE
Mflv_2101|M.gilvum_PYR-GCK SLPKVAENWPVRNLVTNTGFGSG-LDWRPNPGIAFPTYANYLPVTRAVPE
MUL_3918|M.ulcerans_Agy99 SLPIVDNNWPVRNLVTNTGFGTG-MDWRPNPGIGFPGWANYFPVTRGTPE
MSMEG_0346|M.smegmatis_MC2_155 SLPDVAKNFPVRQLVTNTGWGTG-LDIRPNPGIGFPGWANYFPVTRGIPQ
Rv1966|M.tuberculosis_H37Rv PLPDATHNFPVRQLVTNTGWGTG-LDIRPNPGIGHPCWANYFPVTRAVPE
MMAR_2882|M.marinum_M SLPDATKNFPVRQLVTDTGWGTG-LDIRPNPGIGHPCWADYLPVTRAVPQ
MAV_2061|M.avium_104 SLPDPSANFPVRALVTDTGWGAAPNEIRTNVAAGNPWWANWFPTTKNPPE
Mb0604|M.bovis_AF2122/97 QTITRELWP-APYLVMDTG-ASLAPYNHVELGQPMFTEYVWGRQYGENTI
MLBr_02589|M.leprae_Br4923 QHITRDLWP-TPELVMDTG-NSIAPYNHLDSGSPYAIEYVWGRQVGDNTI
MAB_4153c|M.abscessus_ATCC_199 TKMQNGSWFRSPFLVTDNAYIPYKPLEELQVNAPDTLQYLYNGAFAKRSE
** :.. . . : : .
TH_4174|M.thermoresistible__bu HPYVLGE-GPPAPGPSP---SIPHG-PVAAP-----VPAPPVGQSSP---
Mvan_4399|M.vanbaalenii_PYR-1 PPSLRGM-GPPAIGPVPYPGSPPYGGSLYGPDGLPLWAAPPPGMPPP---
Mflv_2101|M.gilvum_PYR-GCK PPSVRNLFGGPAIGPIPYPGAPAYGAQLYAPDGTPLWPGLPPAPPPG---
MUL_3918|M.ulcerans_Agy99 PPSIRNLFGGPAPGPIPYPGAPPYGAELYAPDGTPLWPGLPPAPPPG---
MSMEG_0346|M.smegmatis_MC2_155 PPIIRNLGGGPAPGPIPYPGAPPYGADLYADDGTPLWPGLPPAPPPSDQP
Rv1966|M.tuberculosis_H37Rv PPSIRQCIPGPAIG--PNP----------------------AAGEQP---
MMAR_2882|M.marinum_M PPSVRPCLPGPAIG--PNPGGPPYGAALYGPGGVPLWPGVPPAPTEP---
MAV_2061|M.avium_104 APRYFWRGGQPPP-------------------------------------
Mb0604|M.bovis_AF2122/97 NP------------------------------------------------
MLBr_02589|M.leprae_Br4923 NP------------------------------------------------
MAB_4153c|M.abscessus_ATCC_199 F-------------------------------------------------
TH_4174|M.thermoresistible__bu ------PEPTTDEPTPRTQSGQP---------------------
Mvan_4399|M.vanbaalenii_PYR-1 ------PVPGVPNPPPPYGTGIPPQSHPAPNP------------
Mflv_2101|M.gilvum_PYR-GCK APRDPGPRPGSEPFVVPHPSQMQPTAVPYPFVPPPVPAQPGPPR
MUL_3918|M.ulcerans_Agy99 APRESGPTPGSEPFVVPASAQAQPTPLP----PAPLPQEVAPSP
MSMEG_0346|M.smegmatis_MC2_155 PPDPNNPPPGAEPFVPPAPAAMTPTQ------------------
Rv1966|M.tuberculosis_H37Rv --------------------------------------------
MMAR_2882|M.marinum_M -------APIPEPLAPQQETETPSP-------------------
MAV_2061|M.avium_104 --------------------------------------------
Mb0604|M.bovis_AF2122/97 --------------------------------------------
MLBr_02589|M.leprae_Br4923 --------------------------------------------
MAB_4153c|M.abscessus_ATCC_199 --------------------------------------------