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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2690 | - | - | 100% (425) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2548 | - | e-138 | 57.14% (427) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4174 | - | e-136 | 56.97% (423) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0175 | mce1A | 1e-63 | 35.06% (405) | MCE-family protein MCE1A |
| M. gilvum PYR-GCK | Mflv_2101 | - | 1e-146 | 60.05% (428) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1966 | mce3A | 1e-125 | 56.58% (403) | MCE-family protein MCE3A |
| M. leprae Br4923 | MLBr_02589 | mce1A | 6e-62 | 35.29% (391) | putative cell invasion protein |
| M. abscessus ATCC 19977 | MAB_4153c | - | 6e-57 | 34.54% (359) | MCE-family protein |
| M. marinum M | MMAR_4051 | mce3A_1 | 1e-149 | 61.21% (428) | MCE-family protein Mce3A_1 |
| M. avium 104 | MAV_2532 | - | 1e-134 | 58.19% (397) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_0346 | - | 1e-149 | 61.56% (424) | virulence factor |
| M. ulcerans Agy99 | MUL_3918 | mce3A_1 | 1e-150 | 61.45% (428) | MCE-family protein Mce3A_1 |
| M. vanbaalenii PYR-1 | Mvan_4604 | - | 1e-146 | 60.00% (425) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1966|M.tuberculosis_H37Rv ---MRRGPGRHRLHDAWWTLILFAVIGVAVLVTAVSFTGSLRSTVPVTLA
MSMEG_0346|M.smegmatis_MC2_155 ---MQPRFRDARIKPAWWTWILIAALGVFFFTTGSLFAGTFRSFVPVTLV
MMAR_4051|M.marinum_M -----MDDRKEGLHPAWHTLILVLLFVAAMWVTYALFMGSLRSVVPVTLT
MUL_3918|M.ulcerans_Agy99 -----MDDRKEGLHPAWHTLILVLLFVAAMWVTYALFMGSLRSVVPVTLT
Mvan_4604|M.vanbaalenii_PYR-1 -----MEGHEEGLHPAWWTLILVILTVVALWLTYSLFFGTFRAHETVTLT
Mflv_2101|M.gilvum_PYR-GCK -----MDD--DGLKPGWWTLILVAVFAVAIFVTYALFTGSLKSTVPVTLT
MAV_2532|M.avium_104 ----------------------------------------------MTLT
TH_2690|M.thermoresistible__bu -------------------LLLIASIVCLVVVCSVLFVGAHKSYAPVLLT
Mb0175|M.bovis_AF2122/97 MTTPGKLNKARVPPYKTAGLGLVLVFALVVALVYLQFRGEFTPKTQLTML
MLBr_02589|M.leprae_Br4923 MTSSTKINASRKPPYKLAGVGLLVVAVVIFGLVYGQFRGNFTPKSKLTML
MAB_4153c|M.abscessus_ATCC_199 -----MSDTSTRRAVRLAGTVLASVLVLLTVLTYLAYNDAFADTKPITVV
: :
Rv1966|M.tuberculosis_H37Rv ADRSGLVMDSGAKVMMRGVQVGRVAQIGRIEWA-QNGASLRLEIDPDQIR
MSMEG_0346|M.smegmatis_MC2_155 SDRSGLVMETGAKVKLNGVEVGRVSEIR---GG-ASGVSLQLEIEPDQIR
MMAR_4051|M.marinum_M SERSGLVMETNAKVKLRGVQVGRVASIVGGGKG-ATPVALTLEIDSDQIR
MUL_3918|M.ulcerans_Agy99 SERSGLVMETNAKVKLRGVQVGRVASIVGGGKG-ATPVALTLEIDSDQIR
Mvan_4604|M.vanbaalenii_PYR-1 SERSGLVMETGAKVKLRGVQVGRVSAIQGGSQ----PVALKLEIDKDKIK
Mflv_2101|M.gilvum_PYR-GCK SDRAGLVMETNAKVKLRGVQVGRVSDISVTGRQ-DPTVALQLEIDPDQVQ
MAV_2532|M.avium_104 ADRSGLIMEPGAKVKLRGVQVGRVTSIHSGDP-----VTLRLELYPEQLQ
TH_2690|M.thermoresistible__bu SERSGLVMERGAKVKLRGVEVGRVAQITGGSE----PVKLQLDIEPAKLR
Mb0175|M.bovis_AF2122/97 SARAGLVMDPGSKVTYNGVEIGRVDTISEVTRDGESAAKFILDVDPRYIH
MLBr_02589|M.leprae_Br4923 ADRAGLVMDRGSKITYNGVKIGRVADISETVRNGRPVAEFTLDVYPRYLS
MAB_4153c|M.abscessus_ATCC_199 SPRAGLVMEEGGKVKFHGLQIGKVTSISYAN----DQAKLELAVNAKDLR
: *:**:*: ..*: .*:::*:* * . : * : :
Rv1966|M.tuberculosis_H37Rv YIPANVEAQISATTAFGAKFVDLVMPQNPSRARLSAGAVLHSKNVSTEIN
MSMEG_0346|M.smegmatis_MC2_155 FIPANVEARITATTAFGAKYVDLSYPDNPTGQHLAAGAVLRSRNVSTEVN
MMAR_4051|M.marinum_M YIPANVQAEIRATTVFGAKFVDLVYPQDPSPQRLKAGQVLMSRNVTSEAN
MUL_3918|M.ulcerans_Agy99 YIPANVQAEIRATTVFGAKFVDLIYPEDPSPQRLKAGQVLMSRNVTSEAN
Mvan_4604|M.vanbaalenii_PYR-1 FIPANIEGQIRATTVFGAKFVDLVYPEDPKGQ-LQAGQVIESRNVTVEAN
Mflv_2101|M.gilvum_PYR-GCK YIPANVEAQIRATTIFGAKFVDLVFPDDPSNQRLEAGQVLQSRNVTTEVN
MAV_2532|M.avium_104 YIPANVTAQITATTAFGGKYVDLQIPESPSPRRLAAGAVVRSRNVTTEVN
TH_2690|M.thermoresistible__bu FIPANVEAEIEATTAFGAKFVNLIVPDDPSPQRLSPGDVLTSRNVSTEVN
Mb0175|M.bovis_AF2122/97 LIPANVNADIKATTVFGGKYVSLTTPKNPTKRRITPKDVIDVRSVTTEIN
MLBr_02589|M.leprae_Br4923 LIPANVNADIKATTVFGGKYVSLTTPEHPSQKRLTPQTVIDARSVTTEIN
MAB_4153c|M.abscessus_ATCC_199 LIPSNATVRIAGTTVFGAKSVEFLAPQKPSDSSLRPGATVTAEAVALEVN
**:* * .** **.* *.: *. *. : . .: . *: * *
Rv1966|M.tuberculosis_H37Rv TVFENVVDLLNMIDPLKLNAVLTAVADAVRGQGERIGQATTDLNEVLEAL
MSMEG_0346|M.smegmatis_MC2_155 TVFENLTDVLKMVDPAKLNAVLSALAEGFRGQGERMGQAITDANEVLMAI
MMAR_4051|M.marinum_M TVFQNLVAVLDQIDPAKLNAALSALAEGLRGQGPLIGQATTDANQVLLEL
MUL_3918|M.ulcerans_Agy99 TVFQNLVAVLDQIDPAKLNAALSALAEGLRGQGPLIGQATTDANQVLLEL
Mvan_4604|M.vanbaalenii_PYR-1 TVFQNVVDIIKRIDVAKLNSTLSALADGVRGQGERIGQATTDANQVLLEL
Mflv_2101|M.gilvum_PYR-GCK TVFQNLVAVLDQVDAAKLNSTLSALADGVRGQGERIGRATTDANQVLLAL
MAV_2532|M.avium_104 TVFQNLVAVLNQVDTPKLNAVLTALGDGLRGKGEALGEATTDLNEVLGAI
TH_2690|M.thermoresistible__bu TVFQNLVGVLDQIDVSKLNATLSALADGLQGQGARIGEATTSAKEVLVAM
Mb0175|M.bovis_AF2122/97 TLFQTLTSIAEKVDPVKLNLTLSAAAEALTGLGDKFGESIVNANTVLDDL
MLBr_02589|M.leprae_Br4923 TLFQTITLIAEKVDPIKLNLTLSAAAQSLAGLGERFGQSIVNGNSVLDDV
MAB_4153c|M.abscessus_ATCC_199 TVFENLTRLLGKIDPVNLNATLTAVGEGLRGNGDNFGQGLVELDQYLDQL
*:*:.:. : :* :** .*:* .:.. * * :*.. .. . * :
Rv1966|M.tuberculosis_H37Rv NARGDTIGGNWRSLKNFTDTYDAAAQDILTILNAASTTSATVVNHSTQLD
MSMEG_0346|M.smegmatis_MC2_155 NPRQDTIREDWRAMGEVSAAYDHAADDIVKILDAGTTTAETVTSHRSELD
MMAR_4051|M.marinum_M NPRYETVTADLRAVKDFNDTFSAAAQDILDTLNALSTTSTTITSHSTQLD
MUL_3918|M.ulcerans_Agy99 NPRYETVTADLRAVKDFNDTFSAAAQDILDTLNALSTTSTTITGHSTQLD
Mvan_4604|M.vanbaalenii_PYR-1 NPRNETIAENWRALRDFNDTYSVAAQDILTTLDALSTTSTTITNRATQLD
Mflv_2101|M.gilvum_PYR-GCK NPRNETITEDLRALDQFNQTYSAAAQNILATLDAASTTSTTVVNQAKELD
MAV_2532|M.avium_104 NPRSETIRADSRALEGFSDTYSAAAHDIVTVLDAGSTTSATVSNNAQALD
TH_2690|M.thermoresistible__bu NPRMDTVRENFRSLEGFGDAYAAAADDILDVLDAAATTGTTITERTGDLE
Mb0175|M.bovis_AF2122/97 NSRMPQSRHDIQQLAALGDVYADAAPDLFDFLDSSVTTARTINAQQAELD
MLBr_02589|M.leprae_Br4923 NSQLPQARHDIQQLASLGDTYANSASDFFDFLNNSIVTSRTINQQQKDLD
MAB_4153c|M.abscessus_ATCC_199 NPKLPALQQDFRQAGQVGQIYGDAAPDIVRILDNLPALSRTVVDQQQDLK
*.: : : . : :* ::. *: . . *: . *.
Rv1966|M.tuberculosis_H37Rv ALLLNAIGLSNAGTNLLGSSRDNLVGAADILAPTTSLLFKYNPEYTCFLQ
MSMEG_0346|M.smegmatis_MC2_155 TLLLNVIGFGRAGVDLLAPSFTNLVNAVNGFAPTSDLLMKYQPEYTCLLD
MMAR_4051|M.marinum_M ALLLATIGLSNTGISLLAPNQANLIKAINALEPTTNLLYKYSPEYTCLLE
MUL_3918|M.ulcerans_Agy99 ALLLATIGLSNTGISLLAPNQANLIKAINALEPTTNLLYKYSPEYTCLLE
Mvan_4604|M.vanbaalenii_PYR-1 ALLMATTGLSNSGISLLAPNQANLIKAINVLEPTTNLLHKYSPSYTCLLT
Mflv_2101|M.gilvum_PYR-GCK ALLLAAIGLSNSGIDLLAPNQANLIKAVNTLAPTTNLLHKYSPSYTCLLL
MAV_2532|M.avium_104 SLLLNVIGLSHSGIGLIGPNKDNLVHGVNLLESTTRLLMKYNPELTCTLL
TH_2690|M.thermoresistible__bu DVLLSAVGFGQSGVDLLAPNSDNIVRAIRALQPTTDVLEKYHPTYTCLLQ
Mb0175|M.bovis_AF2122/97 SALLAAAGFGNTTADVFDRGGPYLQRGVADLVPTATLLDTYSPELFCTIR
MLBr_02589|M.leprae_Br4923 QVLLAAVGFGNTGADIFSRSGPYLARGAADLVPTAQLLDTYSPAIFCTLR
MAB_4153c|M.abscessus_ATCC_199 ATLLAAIGLGNNGYETLAPAEKDLTAALQRLRAPATLLGRYSPEIPCTLQ
*: . *:.. : : . : ..: :* * * * :
Rv1966|M.tuberculosis_H37Rv GAKWYLDNGGYAAWGGA-----------DGRTLQLDVALLFGND------
MSMEG_0346|M.smegmatis_MC2_155 GSVSLLQNGHVDAFGG------------NGRSAIFDIGLLLGND------
MMAR_4051|M.marinum_M GAKYLLDHGGYEAPGG------------NGRSLVLDAALALGDD------
MUL_3918|M.ulcerans_Agy99 GAKYLLDHGGYEAPGG------------NGRSLVLDAALALGDD------
Mvan_4604|M.vanbaalenii_PYR-1 GAKTLLDTGGYDAPGG------------NGRTLVLDVGLTLGDD------
Mflv_2101|M.gilvum_PYR-GCK GAKHLLDEGGYEAPGG------------NGRTLVLDTSLSFGDD------
MAV_2532|M.avium_104 GSKYDAEFFGDVAGGH------------NGYSVTLDVALLLGDE------
TH_2690|M.thermoresistible__bu GSVFLLNNMAYDSMGGA-----------NGKSLIVDAGLLLGDD------
Mb0175|M.bovis_AF2122/97 NFYDADPLAKAAAGGGNGYSLRTNSEILSGIGISLLSPLALATNGAAIGI
MLBr_02589|M.leprae_Br4923 NYHDIEPKVTSFLGG-NGYSINDHVELLSGLGFLLNPTSAISIIGAGV--
MAB_4153c|M.abscessus_ATCC_199 AISKALVTFTPLIGG-------------VRPGLFLTNSFPLGAP------
* . :.
Rv1966|M.tuberculosis_H37Rv ------------------------------PYVYPDNLPVVAAKGGP--G
MSMEG_0346|M.smegmatis_MC2_155 ------------------------------PYHYPDDLPIVGAKGGP--G
MMAR_4051|M.marinum_M ------------------------------PYRFPDNLPIIGAKGGP--G
MUL_3918|M.ulcerans_Agy99 ------------------------------PYRFPDNLPIIGAKGGP--G
Mvan_4604|M.vanbaalenii_PYR-1 ------------------------------PYHYPDNLPVIGAKGGP--G
Mflv_2101|M.gilvum_PYR-GCK ------------------------------PYQYPRHLPIIGAKGGP--G
MAV_2532|M.avium_104 ------------------------------AYRYPDNLPINGAKGGP--G
TH_2690|M.thermoresistible__bu ------------------------------PYRYPQHLPRIAAKGGP--G
Mb0175|M.bovis_AF2122/97 GLVAGLIASPLAVAANLAGALPGIVGGAPNPYTYPENLPRVNARGGP--G
MLBr_02589|M.leprae_Br4923 -LSQGLLAP-------LG--LAGVVNGAANPYIYPENLPRVNARGGP--G
MAB_4153c|M.abscessus_ATCC_199 ------------------------------VYTYPDSLPIVNASGGPNCR
* :* ** * ***
Rv1966|M.tuberculosis_H37Rv GRPGCGPLPDATHNFPVRQLVTNTGWGTGLDIRPNPGIGHPCWANYFPVT
MSMEG_0346|M.smegmatis_MC2_155 GKPGCGSLPDVAKNFPVRQLVTNTGWGTGLDIRPNPGIGFPGWANYFPVT
MMAR_4051|M.marinum_M GKPGCGSLPIVDNNWPVRNLVTNTGFGTGMDWRPNPGIGFPGWANYFPVT
MUL_3918|M.ulcerans_Agy99 GKPGCGSLPIVDNNWPVRNLVTNTGFGTGMDWRPNPGIGFPGWANYFPVT
Mvan_4604|M.vanbaalenii_PYR-1 GKPSCGSLPDVAKNWPVRNLVTNTGFGTGIDWRPNPGIGFPAWANYLPTT
Mflv_2101|M.gilvum_PYR-GCK GKPGCGSLPKVAENWPVRNLVTNTGFGSGLDWRPNPGIAFPTYANYLPVT
MAV_2532|M.avium_104 GQPGCGSLPDVSKNFPLRYLVTNTGWGRGLDMRPNPGIGFPGYVDYLPVT
TH_2690|M.thermoresistible__bu GKPSCGSLPDATKKFPVRYLVTDTGFGTGLDIRPNPGIGFPGLANYFPVT
Mb0175|M.bovis_AF2122/97 GAPGCWQPITRDLWP-APYLVMDTG------------------ASLAPYN
MLBr_02589|M.leprae_Br4923 GAPGCWQHITRDLWP-TPELVMDTG------------------NSIAPYN
MAB_4153c|M.abscessus_ATCC_199 GLPNIPTKMQNGSWFRSPFLVTDNAY-----------------IPYKPLE
* *. ** :.. *
Rv1966|M.tuberculosis_H37Rv RAVPEPPSIRQCIPGPAIGPNP-AAGEQP---------------------
MSMEG_0346|M.smegmatis_MC2_155 RGIPQPPIIRNLGGGPAPGPIP-YPGAPPYGADLYADDGTPLWPGLPPAP
MMAR_4051|M.marinum_M RGTPEPPSIRNLFGGPAPGPIP-YPGAPPYGAELYAPDGTPLWPGLPPAP
MUL_3918|M.ulcerans_Agy99 RGTPEPPSIRNLFGGPAPGPIP-YPGAPPYGAELYAPDGTPLWPGLPPAP
Mvan_4604|M.vanbaalenii_PYR-1 RAVPEPPSIRNLFGGPAIGPIP-YPGAPAYGADLYAPDGTPLWPGLPPAP
Mflv_2101|M.gilvum_PYR-GCK RAVPEPPSVRNLFGGPAIGPIP-YPGAPAYGAQLYAPDGTPLWPGLPPAP
MAV_2532|M.avium_104 RGTPQPPSLR-HPGGTAPGPMP-YPGAPPYGAPQYAPDGTPLYPGLPPAP
TH_2690|M.thermoresistible__bu KAMPEPPRIY-HPGGPAPGPEPPYPGGPPHGAPLYGPDGTPLWP---PAP
Mb0175|M.bovis_AF2122/97 HMEVGSPYAVEYVWGRQVGDNTINP-------------------------
MLBr_02589|M.leprae_Br4923 HLDSGSPYAIEYVWGRQVGDNTINP-------------------------
MAB_4153c|M.abscessus_ATCC_199 ELQVNAPDTLQYLYNGAFAKRSEF--------------------------
. .* . . .
Rv1966|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0346|M.smegmatis_MC2_155 PPSDQPPPDPNNPPPGAEPFVPPAPAAMTPTQ------------------
MMAR_4051|M.marinum_M PPG--APRESGPTP-GSEPFVVPAPAQAQPTPLP----PAPLPQEV-APS
MUL_3918|M.ulcerans_Agy99 PPG--APRESGPTP-GSEPFVVPASAQAQPTPLP----PAPLPQEV-APS
Mvan_4604|M.vanbaalenii_PYR-1 PPM--APRDPGPTP-GSEPFIVQHPAQMQPTPLP----PVPLPREA-APS
Mflv_2101|M.gilvum_PYR-GCK PPG--APRDPGPRP-GSEPFVVPHPSQMQPTAVPYPFVPPPVPAQP-GPP
MAV_2532|M.avium_104 PPG--RPRDAGPPPAGSEPFTPPVPGAIQPTCGVLNQVCEPLPPPPNVPG
TH_2690|M.thermoresistible__bu --------------------------------------------------
Mb0175|M.bovis_AF2122/97 --------------------------------------------------
MLBr_02589|M.leprae_Br4923 --------------------------------------------------
MAB_4153c|M.abscessus_ATCC_199 --------------------------------------------------
Rv1966|M.tuberculosis_H37Rv -
MSMEG_0346|M.smegmatis_MC2_155 -
MMAR_4051|M.marinum_M P
MUL_3918|M.ulcerans_Agy99 P
Mvan_4604|M.vanbaalenii_PYR-1 P
Mflv_2101|M.gilvum_PYR-GCK R
MAV_2532|M.avium_104 P
TH_2690|M.thermoresistible__bu -
Mb0175|M.bovis_AF2122/97 -
MLBr_02589|M.leprae_Br4923 -
MAB_4153c|M.abscessus_ATCC_199 -