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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3624 | - | - | 100% (423) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2690 | - | e-134 | 59.01% (405) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2548 | - | e-133 | 59.26% (405) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0604 | mce2A | 1e-60 | 38.20% (356) | MCE-family protein MCE2A |
| M. gilvum PYR-GCK | Mflv_0652 | - | 1e-168 | 69.90% (412) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1966 | mce3A | 1e-134 | 59.23% (417) | MCE-family protein MCE3A |
| M. leprae Br4923 | MLBr_02589 | mce1A | 1e-55 | 33.76% (391) | putative cell invasion protein |
| M. abscessus ATCC 19977 | MAB_4153c | - | 3e-57 | 35.43% (350) | MCE-family protein |
| M. marinum M | MMAR_4051 | mce3A_1 | 1e-146 | 64.23% (411) | MCE-family protein Mce3A_1 |
| M. avium 104 | MAV_2532 | - | 1e-130 | 59.95% (377) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_0346 | - | 1e-142 | 59.33% (418) | virulence factor |
| M. ulcerans Agy99 | MUL_3918 | mce3A_1 | 1e-146 | 63.75% (411) | MCE-family protein Mce3A_1 |
| M. vanbaalenii PYR-1 | Mvan_0500 | - | 1e-168 | 69.90% (412) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0652|M.gilvum_PYR-GCK ---MADGTGARRISPGWWAMLLVTGIVAAVVLSLAMFNRTFTPTVPVTLT
Mvan_0500|M.vanbaalenii_PYR-1 ---MADGTGARRISPGWWAMLLVTGIVAAVVLSLAMFNRTFTPTVPVTLT
TH_3624|M.thermoresistible__bu ---MAARRKTPRIASEWFATMLVVALSGAAALCVAAFNQSFTPSVPVTLT
MMAR_4051|M.marinum_M -----MDDRKEGLHPAWHTLILVLLFVAAMWVTYALFMGSLRSVVPVTLT
MUL_3918|M.ulcerans_Agy99 -----MDDRKEGLHPAWHTLILVLLFVAAMWVTYALFMGSLRSVVPVTLT
MAV_2532|M.avium_104 ----------------------------------------------MTLT
MSMEG_0346|M.smegmatis_MC2_155 ---MQPRFRDARIKPAWWTWILIAALGVFFFTTGSLFAGTFRSFVPVTLV
Rv1966|M.tuberculosis_H37Rv ---MRRGPGRHRLHDAWWTLILFAVIGVAVLVTAVSFTGSLRSTVPVTLA
Mb0604|M.bovis_AF2122/97 -MPTLVTRKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTPKTELTMV
MLBr_02589|M.leprae_Br4923 MTSSTKINASRKPPYKLAGVGLLVVAVVIFGLVYGQFRGNFTPKSKLTML
MAB_4153c|M.abscessus_ATCC_199 -----MSDTSTRRAVRLAGTVLASVLVLLTVLTYLAYNDAFADTKPITVV
:*:
Mflv_0652|M.gilvum_PYR-GCK ADRSGLMLEPNSRVKMRGVQIGRVSAVTGG----DAPR-IQLAIDPDQIR
Mvan_0500|M.vanbaalenii_PYR-1 ADRSGLMLEPNSRVKMRGVQIGRVSAVTGG----DAPR-IQLAIDPDQIR
TH_3624|M.thermoresistible__bu AERSGLVMEPYAKVKMRGVEVGRVAGVSGG----SGRVGLRLEIDPKQIE
MMAR_4051|M.marinum_M SERSGLVMETNAKVKLRGVQVGRVASIVGGGK-GATPVALTLEIDSDQIR
MUL_3918|M.ulcerans_Agy99 SERSGLVMETNAKVKLRGVQVGRVASIVGGGK-GATPVALTLEIDSDQIR
MAV_2532|M.avium_104 ADRSGLIMEPGAKVKLRGVQVGRVTSIHSG-----DPVTLRLELYPEQLQ
MSMEG_0346|M.smegmatis_MC2_155 SDRSGLVMETGAKVKLNGVEVGRVSEIRGG----ASGVSLQLEIEPDQIR
Rv1966|M.tuberculosis_H37Rv ADRSGLVMDSGAKVMMRGVQVGRVAQIGRIEW-AQNGASLRLEIDPDQIR
Mb0604|M.bovis_AF2122/97 ASRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNPRYIS
MLBr_02589|M.leprae_Br4923 ADRAGLVMDRGSKITYNGVKIGRVADISETVRNGRPVAEFTLDVYPRYLS
MAB_4153c|M.abscessus_ATCC_199 SPRAGLVMEEGGKVKFHGLQIGKVTSISYAN----DQAKLELAVNAKDLR
: *:**::: .:: .*:::*:* : : * : . :
Mflv_0652|M.gilvum_PYR-GCK HIPANVEARIQSISLFGAKYVDLVYPPDPSPQRLSAGAVLTSQNTATEVN
Mvan_0500|M.vanbaalenii_PYR-1 HIPANVEARIQSISLFGAKYVDLVYPPDPSPQRLSAGAVLTSQNTATEVN
TH_3624|M.thermoresistible__bu HIPANVEARIDATSLFGTKFVELVYPRQPSPQRLSAGAVLRSQNVAVEVN
MMAR_4051|M.marinum_M YIPANVQAEIRATTVFGAKFVDLVYPQDPSPQRLKAGQVLMSRNVTSEAN
MUL_3918|M.ulcerans_Agy99 YIPANVQAEIRATTVFGAKFVDLIYPEDPSPQRLKAGQVLMSRNVTSEAN
MAV_2532|M.avium_104 YIPANVTAQITATTAFGGKYVDLQIPESPSPRRLAAGAVVRSRNVTTEVN
MSMEG_0346|M.smegmatis_MC2_155 FIPANVEARITATTAFGAKYVDLSYPDNPTGQHLAAGAVLRSRNVSTEVN
Rv1966|M.tuberculosis_H37Rv YIPANVEAQISATTAFGAKFVDLVMPQNPSRARLSAGAVLHSKNVSTEIN
Mb0604|M.bovis_AF2122/97 LIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVTTEFN
MLBr_02589|M.leprae_Br4923 LIPANVNADIKATTVFGGKYVSLTTPEHPSQKRLTPQTVIDARSVTTEIN
MAB_4153c|M.abscessus_ATCC_199 LIPSNATVRIAGTTVFGAKSVEFLAPQKPSDSSLRPGATVTAEAVALEVN
** *. . * . : ** * * : * * : . .: .: * *
Mflv_0652|M.gilvum_PYR-GCK TVFQNVVQLIKTIDPLKLNAVLSALAEGVRGQGDRIGEAITASNQVLLEL
Mvan_0500|M.vanbaalenii_PYR-1 TVFQNVVQLIKTIDPLKLNAVLSALAEGVRGQGDRIGEAITASNQVLLEL
TH_3624|M.thermoresistible__bu TVFQNLVDLIAQIEPAKLNAVLSALSEAVRGQGDRIGVATTDADELLLEL
MMAR_4051|M.marinum_M TVFQNLVAVLDQIDPAKLNAALSALAEGLRGQGPLIGQATTDANQVLLEL
MUL_3918|M.ulcerans_Agy99 TVFQNLVAVLDQIDPAKLNAALSALAEGLRGQGPLIGQATTDANQVLLEL
MAV_2532|M.avium_104 TVFQNLVAVLNQVDTPKLNAVLTALGDGLRGKGEALGEATTDLNEVLGAI
MSMEG_0346|M.smegmatis_MC2_155 TVFENLTDVLKMVDPAKLNAVLSALAEGFRGQGERMGQAITDANEVLMAI
Rv1966|M.tuberculosis_H37Rv TVFENVVDLLNMIDPLKLNAVLTAVADAVRGQGERIGQATTDLNEVLEAL
Mb0604|M.bovis_AF2122/97 TLFETITSIAEKVDPIELNATLSAVAQAPDGLGGKFGESIVNGNQILAQL
MLBr_02589|M.leprae_Br4923 TLFQTITLIAEKVDPIKLNLTLSAAAQSLAGLGERFGQSIVNGNSVLDDV
MAB_4153c|M.abscessus_ATCC_199 TVFENLTRLLGKIDPVNLNATLTAVGEGLRGNGDNFGQGLVELDQYLDQL
*:*:.:. : ::. :** .*:* .:. * * :* . . :. * :
Mflv_0652|M.gilvum_PYR-GCK NPRTDTVREDFRALKGVSDTYSAAAKDIIDTVAAATTTSATVTTHAQQLD
Mvan_0500|M.vanbaalenii_PYR-1 NPRTDTVREDFRALKGVSDTYSAAAKDIIDTVAAATTTSATVTTHAQQLD
TH_3624|M.thermoresistible__bu NSRTDTMRETWRSLAGVSDTYAVAAQDLLDTLNAASTTSETVTSHAQQLD
MMAR_4051|M.marinum_M NPRYETVTADLRAVKDFNDTFSAAAQDILDTLNALSTTSTTITSHSTQLD
MUL_3918|M.ulcerans_Agy99 NPRYETVTADLRAVKDFNDTFSAAAQDILDTLNALSTTSTTITGHSTQLD
MAV_2532|M.avium_104 NPRSETIRADSRALEGFSDTYSAAAHDIVTVLDAGSTTSATVSNNAQALD
MSMEG_0346|M.smegmatis_MC2_155 NPRQDTIREDWRAMGEVSAAYDHAADDIVKILDAGTTTAETVTSHRSELD
Rv1966|M.tuberculosis_H37Rv NARGDTIGGNWRSLKNFTDTYDAAAQDILTILNAASTTSATVVNHSTQLD
Mb0604|M.bovis_AF2122/97 NPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQRDLD
MLBr_02589|M.leprae_Br4923 NSQLPQARHDIQQLASLGDTYANSASDFFDFLNNSIVTSRTINQQQKDLD
MAB_4153c|M.abscessus_ATCC_199 NPKLPALQQDFRQAGQVGQIYGDAAPDIVRILDNLPALSRTVVDQQQDLK
*.: : . : :: *: : . : *: : *.
Mflv_0652|M.gilvum_PYR-GCK TLLLNVVGLSRSGIDLLGASKDNLVKAVNLLEPTTNLLMKYNPMLTCLFV
Mvan_0500|M.vanbaalenii_PYR-1 TLLLNVVGLSRSGIDLLGASKDNLVKAVNLLEPTTNLLMKYNPMLTCLFV
TH_3624|M.thermoresistible__bu ALLVGLAGFSNSGTKVLSPSKDELVNAINRLEPTTNLLMKYNPGLTCLLL
MMAR_4051|M.marinum_M ALLLATIGLSNTGISLLAPNQANLIKAINALEPTTNLLYKYSPEYTCLLE
MUL_3918|M.ulcerans_Agy99 ALLLATIGLSNTGISLLAPNQANLIKAINALEPTTNLLYKYSPEYTCLLE
MAV_2532|M.avium_104 SLLLNVIGLSHSGIGLIGPNKDNLVHGVNLLESTTRLLMKYNPELTCTLL
MSMEG_0346|M.smegmatis_MC2_155 TLLLNVIGFGRAGVDLLAPSFTNLVNAVNGFAPTSDLLMKYQPEYTCLLD
Rv1966|M.tuberculosis_H37Rv ALLLNAIGLSNAGTNLLGSSRDNLVGAADILAPTTSLLFKYNPEYTCFLQ
Mb0604|M.bovis_AF2122/97 AALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELFCMIR
MLBr_02589|M.leprae_Br4923 QVLLAAVGFGNTGADIFSRSGPYLARGAADLVPTAQLLDTYSPAIFCTLR
MAB_4153c|M.abscessus_ATCC_199 ATLLAAIGLGNNGYETLAPAEKDLTAALQRLRAPATLLGRYSPEIPCTLQ
*: * .. * :. * . : ..: ** *.* * :
Mflv_0652|M.gilvum_PYR-GCK GAKTTLDTGYADMLG-GNGKS-----------------------------
Mvan_0500|M.vanbaalenii_PYR-1 GAKTTLDTGYADMLG-GNGKS-----------------------------
TH_3624|M.thermoresistible__bu GAKTALDKGAMDYIG-GNGKS-----------------------------
MMAR_4051|M.marinum_M GAKYLLDHGGYEAPG-GNGRS-----------------------------
MUL_3918|M.ulcerans_Agy99 GAKYLLDHGGYEAPG-GNGRS-----------------------------
MAV_2532|M.avium_104 GSKYDAEFFGDVAGG-HNGYS-----------------------------
MSMEG_0346|M.smegmatis_MC2_155 GSVSLLQNGHVDAFG-GNGRS-----------------------------
Rv1966|M.tuberculosis_H37Rv GAKWYLDNGGYAAWGGADGRT-----------------------------
Mb0604|M.bovis_AF2122/97 NFHDAAPKVADAVGGNGYS-------------------------------
MLBr_02589|M.leprae_Br4923 NYHDIEPKVTSFLGGNGYSINDHVELLSGLGFLLNPTSAISIIGAGVLSQ
MAB_4153c|M.abscessus_ATCC_199 AISKALVTFTPLIGGVRPG-------------------------------
* .
Mflv_0652|M.gilvum_PYR-GCK -----LIMDAALLLGDDPYRYPDHRPINAAKGGE--GGKPSCGSLPDVAQ
Mvan_0500|M.vanbaalenii_PYR-1 -----LIMDAALLLGDDPYRYPDHRPINAAKGGE--GGKPSCGSLPDVAQ
TH_3624|M.thermoresistible__bu -----AVLDAALLLGDDPYRYPDHLPINAAKGGP--GGKPGCGSLPDVAD
MMAR_4051|M.marinum_M -----LVLDAALALGDDPYRFPDNLPIIGAKGGP--GGKPGCGSLPIVDN
MUL_3918|M.ulcerans_Agy99 -----LVLDAALALGDDPYRFPDNLPIIGAKGGP--GGKPGCGSLPIVDN
MAV_2532|M.avium_104 -----VTLDVALLLGDEAYRYPDNLPINGAKGGP--GGQPGCGSLPDVSK
MSMEG_0346|M.smegmatis_MC2_155 -----AIFDIGLLLGNDPYHYPDDLPIVGAKGGP--GGKPGCGSLPDVAK
Rv1966|M.tuberculosis_H37Rv -----LQLDVALLFGNDPYVYPDNLPVVAAKGGP--GGRPGCGPLPDATH
Mb0604|M.bovis_AF2122/97 -----LAAAGTILGAPNPYVYPDNLPRVNAHGGP--GGRPGCWQTITREL
MLBr_02589|M.leprae_Br4923 GLLAPLGLAGVVNGAANPYIYPENLPRVNARGGP--GGAPGCWQHITRDL
MAB_4153c|M.abscessus_ATCC_199 -----LFLTNSFPLGAPVYTYPDSLPIVNASGGPNCRGLPNIPTKMQNGS
. . * :*: * * ** * *.
Mflv_0652|M.gilvum_PYR-GCK NFPVRQLIANTGFGTGLDWRPNPGIGFPGYANYFPVTRAVPEPPSIR-YP
Mvan_0500|M.vanbaalenii_PYR-1 NFPVRQLIANTGFGTGLDWRPNPGIGFPGYANYFPVTRAVPEPPSIR-YP
TH_3624|M.thermoresistible__bu NWPVRYLVTNTGFGTGLDVRPNPGIGFPGWANYFPVTRAVPEPPSIR-YP
MMAR_4051|M.marinum_M NWPVRNLVTNTGFGTGMDWRPNPGIGFPGWANYFPVTRGTPEPPSIRNLF
MUL_3918|M.ulcerans_Agy99 NWPVRNLVTNTGFGTGMDWRPNPGIGFPGWANYFPVTRGTPEPPSIRNLF
MAV_2532|M.avium_104 NFPLRYLVTNTGWGRGLDMRPNPGIGFPGYVDYLPVTRGTPQPPSLR-HP
MSMEG_0346|M.smegmatis_MC2_155 NFPVRQLVTNTGWGTGLDIRPNPGIGFPGWANYFPVTRGIPQPPIIRNLG
Rv1966|M.tuberculosis_H37Rv NFPVRQLVTNTGWGTGLDIRPNPGIGHPCWANYFPVTRAVPEPPSIRQCI
Mb0604|M.bovis_AF2122/97 WP-APYLVMDTG------------------ASLAPYNHVELGQPMFTEYV
MLBr_02589|M.leprae_Br4923 WP-TPELVMDTG------------------NSIAPYNHLDSGSPYAIEYV
MAB_4153c|M.abscessus_ATCC_199 WFRSPFLVTDNAY-----------------IPYKPLEELQVNAPDTLQYL
*: :.. * . *
Mflv_0652|M.gilvum_PYR-GCK GGPAPGPMPYPGAPPYGAPQYGPDGTPLYPGVPVPPPPS------AGPTP
Mvan_0500|M.vanbaalenii_PYR-1 GGPAPGPMPYPGAPPYGAPQYGPDGTPLYPGVPVPPPPS------AGPTP
TH_3624|M.thermoresistible__bu GGPAPGPVTSPGTP--------------------PPP-------------
MMAR_4051|M.marinum_M GGPAPGPIPYPGAPPYGAELYAPDGTPLWPGLPPAPPPG--APRESGPTP
MUL_3918|M.ulcerans_Agy99 GGPAPGPIPYPGAPPYGAELYAPDGTPLWPGLPPAPPPG--APRESGPTP
MAV_2532|M.avium_104 GGTAPGPMPYPGAPPYGAPQYAPDGTPLYPGLPPAPPPG--RPRDAGPPP
MSMEG_0346|M.smegmatis_MC2_155 GGPAPGPIPYPGAPPYGADLYADDGTPLWPGLPPAPPPSDQPPPDPNNPP
Rv1966|M.tuberculosis_H37Rv PGPAIGPNPAAGEQP-----------------------------------
Mb0604|M.bovis_AF2122/97 WGRQYGENTINP--------------------------------------
MLBr_02589|M.leprae_Br4923 WGRQVGDNTINP--------------------------------------
MAB_4153c|M.abscessus_ATCC_199 YNGAFAKRSEF---------------------------------------
. . .
Mflv_0652|M.gilvum_PYR-GCK -------------------------------------
Mvan_0500|M.vanbaalenii_PYR-1 -------------------------------------
TH_3624|M.thermoresistible__bu -------------------------------------
MMAR_4051|M.marinum_M -GSEPFVVPAPAQAQPTP----LPPAPLP-QEVAPSP
MUL_3918|M.ulcerans_Agy99 -GSEPFVVPASAQAQPTP----LPPAPLP-QEVAPSP
MAV_2532|M.avium_104 AGSEPFTPPVPGAIQPTCGVLNQVCEPLPPPPNVPGP
MSMEG_0346|M.smegmatis_MC2_155 PGAEPFVPPAPAAMTPTQ-------------------
Rv1966|M.tuberculosis_H37Rv -------------------------------------
Mb0604|M.bovis_AF2122/97 -------------------------------------
MLBr_02589|M.leprae_Br4923 -------------------------------------
MAB_4153c|M.abscessus_ATCC_199 -------------------------------------