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M. thermoresistible (build 8) TH_2965 (-)

annotation: extracellular solute-binding protein, family 5
coordinates: 1929641 - 1931209
length: 523

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2965--100% (523)extracellular solute-binding protein, family 5
M. thermoresistible (build 8)TH_4152-1e-2728.31% (491) PUTATIVE extracellular solute-binding protein, family 5
M. thermoresistible (build 8)TH_0743-8e-1026.96% (382) POSSIBLE CONSERVED LIPOPROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1311coppA8e-0924.46% (413) periplasmic oligopeptide-binding lipoprotein OppA
M. gilvum PYR-GCKMflv_0119-0.067.24% (519) extracellular solute-binding protein
M. tuberculosis H37RvRv1280coppA9e-0924.46% (413) periplasmic oligopeptide-binding lipoprotein OppA
M. leprae Br4923MLBr_01121-3e-0823.14% (376) putative extracellular solute-binding dependent transport
M. abscessus ATCC 19977-----
M. marinum MMMAR_4139oppA4e-0925.07% (379) periplasmic oligopeptide-binding lipoprotein OppA
M. avium 104MAV_3421-1e-1724.93% (345) extracellular solute-binding protein, family protein 5
M. smegmatis MC2 155MSMEG_6124-6e-2229.79% (282) putative ABC transporter periplasmic oligopeptide-binding
M. ulcerans Agy99MUL_4002oppA2e-0925.46% (377) periplasmic oligopeptide-binding lipoprotein OppA
M. vanbaalenii PYR-1Mvan_3773-3e-2526.24% (465) extracellular solute-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1311c|M.bovis_AF2122/97           MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT
Rv1280c|M.tuberculosis_H37Rv        MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT
MMAR_4139|M.marinum_M               MLTNADR---HDGVQPGPGARSRRPTRPWAR-RRIRCAGAALLTVTLLLA
MUL_4002|M.ulcerans_Agy99           -----------------------------------------MLTVTLLLA
MLBr_01121|M.leprae_Br4923          -------------------------------MIMLSRIVAALLVVGLILT
TH_2965|M.thermoresistible__bu      ----------------------------------------------MRIW
Mflv_0119|M.gilvum_PYR-GCK          ----------------------------------------MCSDRHMNFR
Mvan_3773|M.vanbaalenii_PYR-1       -----------------------------------------------MRT
MSMEG_6124|M.smegmatis_MC2_155      ------------------------------------------MRRAPHPL
MAV_3421|M.avium_104                -------------------------------------------MAKVASR
                                                                                      

Mb1311c|M.bovis_AF2122/97           GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP
Rv1280c|M.tuberculosis_H37Rv        GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP
MMAR_4139|M.marinum_M               GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP
MUL_4002|M.ulcerans_Agy99           GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP
MLBr_01121|M.leprae_Br4923          GCSAS-NRLVPSAASN--AALGKTSDINPQDPATLKDGGNLRLALTDFPA
TH_2965|M.thermoresistible__bu      ALPVAAAALLLIAGCT------AAP--EHEGQIVLAEA----QELGGYNP
Mflv_0119|M.gilvum_PYR-GCK          VATVLASVLVAVTACS------SSSPAEPRDQIVLAEG----YELGGFNP
Mvan_3773|M.vanbaalenii_PYR-1       VVLATCVFLAALTGCS------------PGDRVDLGAG-AADALIAAIAG
MSMEG_6124|M.smegmatis_MC2_155      ALIAGLAIITSGAAAG------------CTVANTAHGGYDPDTLRIVLPQ
MAV_3421|M.avium_104                TATLGAMLCVLAAGCS------------GHRHTASTGPTGPPVRGGTLTY
                                                .                                     

Mb1311c|M.bovis_AF2122/97           NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA
Rv1280c|M.tuberculosis_H37Rv        NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA
MMAR_4139|M.marinum_M               NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN
MUL_4002|M.ulcerans_Agy99           NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN
MLBr_01121|M.leprae_Br4923          NFNILHIDGNNAEVTSMMKATMPRAFIIGTDGSTTVDTNYFTSIKLTSTS
TH_2965|M.thermoresistible__bu      ------VSGYGEAGVSPLYEALFRPEAD-SDDTVPDLVPALAAGEPEQLG
Mflv_0119|M.gilvum_PYR-GCK          ------VNGYAESGVSPIYDGLYRPSAT-TDAVIPELVPALAAQEPQPAG
Mvan_3773|M.vanbaalenii_PYR-1       EPDQLDPHKTTSYFSFEVLENVFDTLVE-PDGNLQMQPALARAWEVSPD-
MSMEG_6124|M.smegmatis_MC2_155      EPPTLEPCESSLTSTGVVVRSNITEPLIERDPQTGDLLPLLATG-WHQTS
MAV_3421|M.avium_104                SDVQFVTDTMAANYSANNLMFQLLDRVVYVDPKTDAVRGWLAKTFSRNQN
                                                                  *                   

Mb1311c|M.bovis_AF2122/97           PQVVTYTINPEAVWSDGTPITWRDIASQIHAISGADKAFEIASSSGAERV
Rv1280c|M.tuberculosis_H37Rv        PQVVTYTINPEAVWSDGTPITWRDIASQIHAISGADKAFEIASSSGAERV
MMAR_4139|M.marinum_M               PQVITYTINPKAFWSDGTPITWRDIASQIHATSGADNRFEIASSGGSDRV
MUL_4002|M.ulcerans_Agy99           PQVITYTINPKAFWSDGTPVTWRDIASQIHATSGADNRFEIASSGGSDRV
MLBr_01121|M.leprae_Br4923          PQVVTYTINPKAVWSDGTPITWRDIDRQIHANSGKNKAFEIAGTNGCERV
TH_2965|M.thermoresistible__bu      PRRWRIPLRTDVVFSDGTPFDAADVVATYTAVRNPEVASDIATH-----V
Mflv_0119|M.gilvum_PYR-GCK          PNRWRVPLRPGVVFSDGTTFDPVDVVATYDAVRDPRVASEISTS-----V
Mvan_3773|M.vanbaalenii_PYR-1       QLTWTFHLRPGVTFHDGTPLTADDVVFSYRRIIDEQLANSDKFS------
MSMEG_6124|M.smegmatis_MC2_155      PREWTFDIRPGVTFSDGTPFTAADAAFSIDRAVNSDLQCNVDGYVFG---
MAV_3421|M.avium_104                ATRYTFTIRDGVSFSDHTPLTAEVVKANFDQLGKGDPAKKMPAFAD--FV
                                           :.  . : * *..                   .          

Mb1311c|M.bovis_AF2122/97           ASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLPASMTATPEAFNKGQL
Rv1280c|M.tuberculosis_H37Rv        ASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLPASMTATPEAFNKGQL
MMAR_4139|M.marinum_M               ASVTPGVDDRQAIVTFAKPYAEWRGMFAGNGMLLPSSMTATPEAFNKGQL
MUL_4002|M.ulcerans_Agy99           ASVIPGVDDRQAMVTFAKPYAEWRGMFAGNGMLLPSSMTATPEAFNKGQL
MLBr_01121|M.leprae_Br4923          ASIRPGANDRQAIVTFAQPYAEWRGMFAGNGMLLPATMTATPEAFNKGQL
TH_2965|M.thermoresistible__bu      APVAQVRADGEDAVVVDMHTDADPKPYLLVGIAPAERVESKPAANWKLNT
Mflv_0119|M.gilvum_PYR-GCK          APIVSIEADGPDAVVVELDTAADPKPYLLLGILPSERVEATPAADWAVNT
Mvan_3773|M.vanbaalenii_PYR-1       -SVAAVDAPDPNTVVIRVDRPTPNMLTNLGGFKGMAIVSRANVESGRIAT
MSMEG_6124|M.smegmatis_MC2_155      DDPLKVSAPDDHTVVVGTAKPDPILPLRISFIEIVPHTTSVTEKVR----
MAV_3421|M.avium_104                GYDHSEVSGNVVTVFLDRPNTNFYKVLSYSRAGIRAPATLALDYQRQAKV
                                                 * .                                  

Mb1311c|M.bovis_AF2122/97           DGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG-------ARPRLDSITY-
Rv1280c|M.tuberculosis_H37Rv        DGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG-------ARPRLDSITY-
MMAR_4139|M.marinum_M               AGPGPSAGPFIVTSLDRSAQRIVLTRNPKWWG-------KKPRLDSITY-
MUL_4002|M.ulcerans_Agy99           TGPGPSAGPFIVTSLDRSAQRIVLIRNPKWWG-------KKPRLHSITY-
MLBr_01121|M.leprae_Br4923          DRPGPSAGPFIVSSLDRTTQRIVLTHNPKWWG-------TPPRLDSITY-
TH_2965|M.thermoresistible__bu      EPVG--TGPYRLESLR--PDQAVLVARDDYWG-------EPAQVRRIVYT
Mflv_0119|M.gilvum_PYR-GCK          APVG--TGPYRLDSLR--PDQAVLVARDDYWG-------DAPQVRRLVYT
Mvan_3773|M.vanbaalenii_PYR-1       QPVG--TGPFRFLGQK-SGDSISLAANPNYWD-------GPPGVSGVTYR
MSMEG_6124|M.smegmatis_MC2_155      EPIG--TGPYAIERWEY-GQKLVLHRNERYWG-------AAPDFTRAEYQ
MAV_3421|M.avium_104                ENVIG-SGPFVYQSQIPDQQVVLTRRPDYAWPPSSWPNQGPAYVDKVVFR
                                          :**:         :          *          . .    : 

Mb1311c|M.bovis_AF2122/97           LVLDDAARLPALQNNTIDATGVGTLDQLTIAARTKGISIRRAPGPSWYHF
Rv1280c|M.tuberculosis_H37Rv        LVLDDAARLPALQNNTIDATGVGTLDQLTIAARTKGISIRRAPGPSWYHF
MMAR_4139|M.marinum_M               LVLDDAARIPALQNFTIDATGIGSLDQLTIAERTKGISIRRAPAPSWSHF
MUL_4002|M.ulcerans_Agy99           LVLDDAARIPALQNFTIDATGIGSLDQLTIAERTKGISIRRAPAPSWSHF
MLBr_01121|M.leprae_Br4923          LVLDDAARLPALQNNTIDATGVGTLDQLTTAQRTNGISIRRTPAPRWSHF
TH_2965|M.thermoresistible__bu      HTPDDNVRAQRILAGEVDGVSLPPKLISSID--RDDIDAIAVQSADWRGV
Mflv_0119|M.gilvum_PYR-GCK          YAPDDNARAQSMVSGAVDGTNLPPRLIDSVKGSNDDVQTVAVRSADWRGI
Mvan_3773|M.vanbaalenii_PYR-1       FISEPSTALSALQAGEIDWTDSVPPQRVTQLRDDESLELAVTPSNDYWYL
MSMEG_6124|M.smegmatis_MC2_155      WRSEGSVRAAMVVNDEADIG-------TSVGPEDGAGDLGVPFPNNETTA
MAV_3421|M.avium_104                VIGEPGLRAGAVQSHQVDVARGIQPTDEPALKQGGLQVIPVAAPAETANL
                                       :       :     *          .                     

Mb1311c|M.bovis_AF2122/97           TLNGAPGSILADKALRLAIAKGIDRYTIARVAQYGLTSDPVPLNNHVFVA
Rv1280c|M.tuberculosis_H37Rv        TLNGAPGSILADKALRLAIAKGIDRYTIARVAQYGLTSDPVPLNNHVFVA
MMAR_4139|M.marinum_M               TLNGAPGAVLADPALRLAVCKGIDRRTIAKVALYGLTNDPAPLNNHVFVA
MUL_4002|M.ulcerans_Agy99           TLNGAPGAVLADPALRLAVCKGIDRRTIAKVALYGLTNDPAPLNNHVFVA
MLBr_01121|M.leprae_Br4923          TFNGAVGSILADQGLRLAVSKGIDRRTIAKVVQYGLANNPEPLNNHVYVD
TH_2965|M.thermoresistible__bu      ALP-ARNAFTADPRARLAMNLAVDRDAIIRDVLDGYG---RPAGTPIATV
Mflv_0119|M.gilvum_PYR-GCK          ALP-ADNPFTADVTARLAMNVGIDRDALVRDVLVGYG---SPAATPVADA
Mvan_3773|M.vanbaalenii_PYR-1       ALNEAREPWN-DVRVRQAVAYAVDRDAIVQATSYGTA-----AVNQLAIP
MSMEG_6124|M.smegmatis_MC2_155      LRLTATEPPLDDLRVRQAINYSVNRTGIVKALYRGLG----EPAAQLIPE
MAV_3421|M.avium_104                VGFRINNQVVDDVRVRRALQLGIDRRAVVDTVLSDSYR----AADSVLGH
                                               *   * *:  .::*  :      .           :   

Mb1311c|M.bovis_AF2122/97           GQDGYQDNSGVVAYNPEQAKRELDALGWRRS-GAFREKDGRQLVIRDLFY
Rv1280c|M.tuberculosis_H37Rv        GQDGYQDNSGVVAYNPEQAKRELDALGWRRS-GAFREKDGRQLVIRDLFY
MMAR_4139|M.marinum_M               GQEGYQDNS--SPYDPEQAKRELDALGWKLN-GKFREKDGHQLVVRLLFY
MUL_4002|M.ulcerans_Agy99           GQEGYQDNS--SPYDPEQAKRELDALGWKLN-GKFREKDGHQLVVRLLFY
MLBr_01121|M.leprae_Br4923          GQEGYQDNSGVVGYDPEQAQHELDALGWKLN-GQFREKDGRQLVIRYLFY
TH_2965|M.thermoresistible__bu      YGPAYHPDAQ-FDHAPERAATVLDTAGWRVGPDGIREKDGARASFELLYN
Mflv_0119|M.gilvum_PYR-GCK          YGDAYDPGAQ-YVFDLDRARNLLDDAGWRPGAGQIREKDGARASFELLYN
Mvan_3773|M.vanbaalenii_PYR-1       QGNPW--------FTPYDRYRDDGEQGLETARTLLREAGAQPRELDMLVT
MSMEG_6124|M.smegmatis_MC2_155      GVVGHNEDLELWPYDPDRARELIDEA-------RADGVPVDREIRLIGRN
MAV_3421|M.avium_104                DDPLFADVSADIGYQPQRAAGLLDAAGWKPGGDGVREKDGKKLVLTLAAS
                                                 .         .                          

Mb1311c|M.bovis_AF2122/97           DAQSTR-QFAQIAQHTLAQIGVKLELQAKS-GSGFFSDYVNVGAFDIAQF
Rv1280c|M.tuberculosis_H37Rv        DAQSTR-QFAQIAQHTLAQIGVKLELQAKS-GSGFFSDYVNVGAFDIAQF
MMAR_4139|M.marinum_M               EAQSSR-QFAQVAQYSLAQIGVKLELQSRS-GSGFFSNYVNVGAFDIALF
MUL_4002|M.ulcerans_Agy99           EAQSSR-QFAQVAQYSLAQIGVKLELQSRS-GSGFFSNYVNVGAFDIALF
MLBr_01121|M.leprae_Br4923          DAQGSR-EFAQLAQHSLAQIGVKLELQAKA-GSGFFTNYVNVGAFDIVQF
TH_2965|M.thermoresistible__bu      AADTLRRDLAVAFATAMRPLGIDVRTRGTS-WDEIETRTADSAILLGGGS
Mflv_0119|M.gilvum_PYR-GCK          AQDTLRRDLAVAYAAAMKPLGVDVRPRGTS-WDEIDTRFADSAVVLGGGA
Mvan_3773|M.vanbaalenii_PYR-1       TEYPETVTAAQIIADNLAPLGISVKIRTVD-FATWLDE-QNSGNFDMLMM
MSMEG_6124|M.smegmatis_MC2_155      SLFPKVTETVEVIQNELSKIGLNVKIEMMDTAAQLQYQLRPFPPNAGAFI
MAV_3421|M.avium_104                NQSVVFRPAFEFIEQQWRELGVVLQNRAGD--TTFFNASSSQSSTP----
                                                       :*: :. .                       

Mb1311c|M.bovis_AF2122/97           G--WVGDAFPLSSLTQIYASDGESNFGKIGSPQIDAAIERTLAELDPGKA
Rv1280c|M.tuberculosis_H37Rv        G--WVGDAFPLSSLTQIYASDGESNFGKIGSPQIDAAIERTLAELDPGKA
MMAR_4139|M.marinum_M               G--WVGDAFPLSSLTQIYMSDGESNFGKIGSPQIDAAIERTLQELDPAKA
MUL_4002|M.ulcerans_Agy99           G--WVGDAFPLSSLTQIYMSDGESNFGKIGSPQIDAAIERTLQELDPAKA
MLBr_01121|M.leprae_Br4923          G--WVGDAFPLSALTQIYQSDGESNFGKISSPAVDAAIERTLAELDPAKA
TH_2965|M.thermoresistible__bu      TPYSIDAQVYDTLHTRVPGSSPYANPGNFTAPGLDELLDRARELPGGPEK
Mflv_0119|M.gilvum_PYR-GCK          TPYSIDSQVYDTLHTRVPDSSPYSNPGNFTAPGLDALLEQAAQSPSGPAK
Mvan_3773|M.vanbaalenii_PYR-1       G--WLGNIDPDDFYYAQHHTDGTSNAQKFSDPEVDRLLDASRVETDEAAR
MSMEG_6124|M.smegmatis_MC2_155      ALIQHGNQAGDAAFSVDQYMRSDGAQSAYGTPEFDARIEAAGELTGEQRQ
MAV_3421|M.avium_104                ---LFGTRIQYNIGLGLLFGRPKSNLTFAQNDALLALSEEELRQTDPTRL
                                         .                 .         .    :      .    

Mb1311c|M.bovis_AF2122/97           RALANQVDELIWAEGFSLPLTQSPGTVAVR-------STLANFGATGLAD
Rv1280c|M.tuberculosis_H37Rv        RALANQVDELIWAEGFSLPLTQSPGTVAVR-------STLANFGATGLAD
MMAR_4139|M.marinum_M               LALANEVDKLIWAEGFSLPLTQSPGTIAVR-------STLANFGARGLAD
MUL_4002|M.ulcerans_Agy99           LALANQVDKLIWAEGFSLPLTQSPGTIAVR-------STLANFGARGLAD
MLBr_01121|M.leprae_Br4923          RALANEVDKLLWAEGFSLPLTQSPGDVAVR-------STLANFGAAGFGD
TH_2965|M.thermoresistible__bu      DDLYRRIQEVYAAEPSHVFLVFLDHTYGSRDRGWDPVQPILEPHSHGVTW
Mflv_0119|M.gilvum_PYR-GCK          DALYREIQARYAAAPSHVFLVFLHHTYSYRDLGWQQSAPIMEPHSHGVSW
Mvan_3773|M.vanbaalenii_PYR-1       KEQYAGAATLIADKVSYIYLYNPSVIQAWN-------PALSGYEARRDGA
MSMEG_6124|M.smegmatis_MC2_155      QAYAQIFADEPDEIAQFAYIAHMTGVLAKS------PRVDYQPNSATGDE
MAV_3421|M.avium_104                KDVVAREQRRIIDDQLALVLWDEVQVHAAAP------NVHVEFTRYTEPL
                                                       :       .                      

Mb1311c|M.bovis_AF2122/97           LDYTAIGFMRR-----
Rv1280c|M.tuberculosis_H37Rv        LDYTAIGFMRR-----
MMAR_4139|M.marinum_M               LDYTAIGFMRS-----
MUL_4002|M.ulcerans_Agy99           LDYTAIGFMRS-----
MLBr_01121|M.leprae_Br4923          LNYTAIGFMQN-----
TH_2965|M.thermoresistible__bu      GPWWRIGAWTR-----
Mflv_0119|M.gilvum_PYR-GCK          GPWWNLAAWTR-----
Mvan_3773|M.vanbaalenii_PYR-1       VRFRSATFGADGGA--
MSMEG_6124|M.smegmatis_MC2_155      MRLSQMTFAADDTVEH
MAV_3421|M.avium_104                LQSAWKA---------