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M. thermoresistible (build 8) TH_4141 (-)

annotation: DitF protein
coordinates: 3002796 - 3003989
length: 398

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4141--100% (398)DitF protein
M. thermoresistible (build 8)TH_4566-e-10349.47% (380) PUTATIVE putative diterpenoid dioxygenase
M. thermoresistible (build 8)TH_3582-e-10149.74% (386) PUTATIVE protein of unknown function DUF35

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3570cltp21e-4331.66% (398) lipid-transfer protein
M. gilvum PYR-GCKMflv_2483-5e-9749.10% (389) hypothetical protein Mflv_2483
M. tuberculosis H37RvRv3540cltp21e-4331.66% (398) lipid-transfer protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0618-9e-4933.42% (398) lipid-transfer protein
M. marinum MMMAR_4731-2e-9548.35% (393) 3-ketoacyl-CoA thiolase
M. avium 104MAV_1865-0.090.18% (397) DitF protein
M. smegmatis MC2 155MSMEG_4814-1e-10047.51% (402) hypothetical protein MSMEG_4814
M. ulcerans Agy99MUL_3406-2e-8546.48% (383) acetyl-CoA acetyltransferase
M. vanbaalenii PYR-1Mvan_4171-1e-9849.61% (389) hypothetical protein Mvan_4171

CLUSTAL 2.0.9 multiple sequence alignment


TH_4141|M.thermoresistible__bu      --------------------------------------------------
MAV_1865|M.avium_104                --------------------------------------------------
MUL_3406|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK          MSRLP---LPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRYC
Mvan_4171|M.vanbaalenii_PYR-1       MSRLP---LPQLTFDNEFFWKSGADGVLRIQECGDCKALIHPPQPVCRYC
MMAR_4731|M.marinum_M               MSAAPGRPLPLITDENEFFWTSGADGKLRLQECAACASLIHPPAPVCRYC
MSMEG_4814|M.smegmatis_MC2_155      MSQIPGRPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRYC
Mb3570c|M.bovis_AF2122/97           --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_4141|M.thermoresistible__bu      --------------------------------------------------
MAV_1865|M.avium_104                --------------------------------------------------
MUL_3406|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK          HSHNMGPREVSGRAVLSAFTVNHRFSIPGLEAPYVVAQVAIEEDPRVRLT
Mvan_4171|M.vanbaalenii_PYR-1       HSHNMGPREVSGRAVLSAFTVNHRFSIPGLQAPYVVAQVAIEEDPRVRLT
MMAR_4731|M.marinum_M               RSRDMGVRTVSGAATLTGFTVNHRFSLPGLPAPYVIAQVAIAEDPRVRLT
MSMEG_4814|M.smegmatis_MC2_155      RSHDLGVRDVSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRVRLT
Mb3570c|M.bovis_AF2122/97           --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_4141|M.thermoresistible__bu      --------------------------------------------------
MAV_1865|M.avium_104                --------------------------------------------------
MUL_3406|M.ulcerans_Agy99           --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK          TNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEPETAALPDDEIAP
Mvan_4171|M.vanbaalenii_PYR-1       TNIIDCDPDELELGRVVEVVFEENDDVWLPLFRPTAETETAPLPEDEIAP
MMAR_4731|M.marinum_M               TNIVECDPDRLELGQTVEVVFERIEDVWLPLFRPRTDAQPRPLPVDEIAP
MSMEG_4814|M.smegmatis_MC2_155      TNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADTTPTPAPVEDIAP
Mb3570c|M.bovis_AF2122/97           --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

TH_4141|M.thermoresistible__bu      ----------MSRGPFDGKAVLTGAGKSQVGRRLGRTGLDLTLEAVLRAI
MAV_1865|M.avium_104                ----MANVTKMTGGPFDGKAVITGAGKSQVGRRLGRTGLDLTLEAVLRAI
MUL_3406|M.ulcerans_Agy99           ------------------------------------------MEAVRAAV
Mflv_2483|M.gilvum_PYR-GCK          QEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAI
Mvan_4171|M.vanbaalenii_PYR-1       QDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSPLSLTVEACEAAI
MMAR_4731|M.marinum_M               QRFGEHVRPMLTTQKFEDKVALTGIGMSTIGRRLMVAPLSLTVDACEAAV
MSMEG_4814|M.smegmatis_MC2_155      QDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAV
Mb3570c|M.bovis_AF2122/97           --------------MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDAL
Rv3540c|M.tuberculosis_H37Rv        --------------MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDAL
MAB_0618|M.abscessus_ATCC_1997      ------------MTGLSGRSAIAGIGATDFSKKSGRSELRLAAEAVLDAL
                                                                               :*   *:

TH_4141|M.thermoresistible__bu      ADAGLDVDDIDGIASYPGPGVPDPGFSGAGIHDVRNALGLRSRWYISSME
MAV_1865|M.avium_104                EDAGLAVDDVDGIASYPGPGVPDPGFSGATIQEVRNALGLRCRWYVSAME
MUL_3406|M.ulcerans_Agy99           ADAGLTPADVDGIATLG----------DTPAADVNAELQIDAPDCGTGFG
Mflv_2483|M.gilvum_PYR-GCK          ADAGLTLADIDGLSTYPAMDAMG--MGEGGCTVLEGALGIRPTWINGGMD
Mvan_4171|M.vanbaalenii_PYR-1       ADAGLTLADIDGLSTYPAMDAMG--MGEGGVTALEGALGIRPTWINGGMD
MMAR_4731|M.marinum_M               ADAGLTFDDIDGLSTYPGGGNLGG-FGEGGVTALEAALGIRPVWHNGGIE
MSMEG_4814|M.smegmatis_MC2_155      ADAGLTFDDIDGLSTYPGLDIAG--MGEGGVSVLEGALGLRPTWINGGMD
Mb3570c|M.bovis_AF2122/97           ADAGLSPTDVDGLTTFT--------MDTNTEIAVARAAGIGELTFFSKIH
Rv3540c|M.tuberculosis_H37Rv        ADAGLSPTDVDGLTTFT--------MDTNTEIAVARAAGIGELTFFSKIH
MAB_0618|M.abscessus_ATCC_1997      DDAGLSPSDVDGLVTFT--------MDSNLETAVARATGIGELKFFSQIG
                                     ****   *:**: :                  :     :        : 

TH_4141|M.thermoresistible__bu      TAG--QIGPVMEACMAVSLGLANHVVVFRSVWES--TAAQQGGGGRASVL
MAV_1865|M.avium_104                TAG--QIGPVIEACMAVTLGLANHVVVYRSVWES--TAAQQAGGGRASVL
MUL_3406|M.ulcerans_Agy99           TGG--LLSPVMSACRAVAERRARHVIVYRTIQMLGGTVALQPEQDAPAPP
Mflv_2483|M.gilvum_PYR-GCK          TFG--PGGSLIAAVMAVATGMARHVLCFRTLWEA--TFNQLMKEGKASPP
Mvan_4171|M.vanbaalenii_PYR-1       TFG--PGGSVIAAVMAVATGMARHVLCFRTLWEA--TFNQLMKEGRVSPP
MMAR_4731|M.marinum_M               TFG--PGGSVIAAMLAVAGGLARHVLCFRTLWEA--TYNELMKRGKIAPP
MSMEG_4814|M.smegmatis_MC2_155      TFG--PGGSVIAAMMAISAGLARHVLCFRTLWEA--TFGQLVKEGKMSPP
Mb3570c|M.bovis_AF2122/97           YGGGAACATVQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENA
Rv3540c|M.tuberculosis_H37Rv        YGGGAACATVQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENA
MAB_0618|M.abscessus_ATCC_1997      YGGGAAAATVQQAALAVAAGVAEVVVAYRAFNERSEFRFGQVMTGLSSTA
                                      *    ..:  *  *::   *  *: :*:.                   

TH_4141|M.thermoresistible__bu      FS-------------GGKLPPHLEWVAPFGALSAANWLAMPAQRYMQEYG
MAV_1865|M.avium_104                FS-------------GGKLPSHLEWVAPFGALSAANWLAMPAQRYMHDFG
MUL_3406|M.ulcerans_Agy99           LARMFDVAEGAPRPAVGPMDDITDLIAAH-AYSAANWLALNCRRHMELYG
Mflv_2483|M.gilvum_PYR-GCK          GGA-----------------RVNSWQAPFGATSAAHTLALNAQRHFHRYG
Mvan_4171|M.vanbaalenii_PYR-1       GGT-----------------RVNSWQAPFGATSAAHTLALNAQRHFHRYG
MMAR_4731|M.marinum_M               GG------------------RTTSWQYPFGATSAAHTLAINAQRHFHRYG
MSMEG_4814|M.smegmatis_MC2_155      MSA-----------------RTNSWQQPYGATSAAHTLAQNAGRHFHRYG
Mb3570c|M.bovis_AF2122/97           DST----------------GVDNSFSYPHGLSTPAAQVAMIARRYMHLSG
Rv3540c|M.tuberculosis_H37Rv        DST----------------GVDNSFSYPHGLSTPAAQVAMIARRYMHLSG
MAB_0618|M.abscessus_ATCC_1997      DSR----------------GVEYSWSYPHGLSTPAASVAMIARRYMHEYG
                                     .                     .   ..   :.*  :*  . *::.  *

TH_4141|M.thermoresistible__bu      LTREQLGAIAINARRNAGLNPDAIYR-EPMTMDDYLGARMISEPLCLYDC
MAV_1865|M.avium_104                LTREQLGWIALNARRNAGLNPDAVYR-EPMTMDGYLGARMISEPLCLYDC
MUL_3406|M.ulcerans_Agy99           TTREQLGWVALNGRRNAALNPLAVYR-EPMTMADYLGARPVSTPLGLLDC
Mflv_2483|M.gilvum_PYR-GCK          TTKETLGWIALNQRANAALNPTAIYR-DPMTMQDYLNARPITTPFGLYDC
Mvan_4171|M.vanbaalenii_PYR-1       TTKETLGWIALNQRANAALNPTAIYR-DPMTMDDYLNARPITTPFGLYDC
MMAR_4731|M.marinum_M               TTKETLGWIALNQRANAELNPTAVYR-SPMTMDDYLNARPITTPFGLFDC
MSMEG_4814|M.smegmatis_MC2_155      TTRETLGWIALNQRANAALNPTAIYR-EPLTMEDYLSARTITTPFGLYDC
Mb3570c|M.bovis_AF2122/97           ATSRDFGAVSVADRKHAANNPKAYFYGKPITIEDHQNSRWIAEPLRLLDC
Rv3540c|M.tuberculosis_H37Rv        ATSRDFGAVSVADRKHAANNPKAYFYGKPITIEDHQNSRWIAEPLRLLDC
MAB_0618|M.abscessus_ATCC_1997      ATSADFGAVSVADRKHAATNPKAFFYGKPITIEDHQNSRMIADPVRLLDC
                                     *   :* :::  * :*  ** * :  .*:*: .: .:* :: *. * **

TH_4141|M.thermoresistible__bu      DIPCDGATAVIVSRRDAAKGLPRHPLTVGSVGPGMFER----ATWDQRSD
MAV_1865|M.avium_104                DVPCDGATAVIVSRRDATKGLPRYPLTVESVGPGMFER----ATWDQRSD
MUL_3406|M.ulcerans_Agy99           DVPIDGCVAVLVSTAEYARDCPPRAVRVEAIG-GSDGS----GGWFHRAD
Mflv_2483|M.gilvum_PYR-GCK          DVPCDGAVAVIVSAVDAAADAPKPPVFFEAVGTQIIER----TDWDQTTL
Mvan_4171|M.vanbaalenii_PYR-1       DVPCDGAVAVVVSAVDAAVDLPKPPVYFEAVGTQIIER----TDWDQTTL
MMAR_4731|M.marinum_M               DVPCDAAIAVIVSAVDAARDLAKPPVLVEAVGTQIIER----IDWDQSTL
MSMEG_4814|M.smegmatis_MC2_155      DVPCDGAVAVIVSAVDAARDLPRPPIRFEAVGTQIIER----LDWDQTTL
Mb3570c|M.bovis_AF2122/97           CQETDGAVAIVVTSAARARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPEL
Rv3540c|M.tuberculosis_H37Rv        CQETDGAVAIVVTSAARARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPEL
MAB_0618|M.abscessus_ATCC_1997      CQESDGGVAIVVTTPERAKDLKNRPVIIEAAAQGSGEDQFTMYSYYRDEL
                                        *.  *::*:    : .    .: . : .            : :   

TH_4141|M.thermoresistible__bu      LTTMAAHDSAATLWQNTTLTPKDVDMAQIYDGFSFLTVMWLEALGFCEHG
MAV_1865|M.avium_104                ITTMAAHDSGATLWQNTTLTPADVDMAQLYDGFSFLTVMWLEALGFCEHG
MUL_3406|M.ulcerans_Agy99           YPKMAMSDAAAQMWSRTALKPADLEVAQLYDGFTFLTLAWLEALGICADG
Mflv_2483|M.gilvum_PYR-GCK          THEPQVLGQAAHLWTRTSLRPDDVDVAELYDGFTFNCLSWLEALGFCGIG
Mvan_4171|M.vanbaalenii_PYR-1       THEPQVLGQAAHLWTRTSLRPADVDVAELYDGFTFNCLSWLEALGFCGIG
MMAR_4731|M.marinum_M               THEPQVLGQAAHVWTRTTLRPADVDVAELYDGFTMNCLSWIEALGFCGIG
MSMEG_4814|M.smegmatis_MC2_155      THEPQVLGQSAHMWSRTSLRPSDVDVAELYDGFTFNCLSWLEGLGFCGIG
Mb3570c|M.bovis_AF2122/97           DGLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKG
Rv3540c|M.tuberculosis_H37Rv        DGLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKG
MAB_0618|M.abscessus_ATCC_1997      G-LPEMGLVGRQLWDQSGLTPNDIQTAILYDHFTPYTLLQLEELGFCGKG
                                             .  :* .: * * *:: * :** *:   :  :* **:*  *

TH_4141|M.thermoresistible__bu      RVGEFIEGGQRIALDGDLPINTSGGQLSAGRLHGMGFLHEACVQMWGEGG
MAV_1865|M.avium_104                KVGDFIEGGERIAIDGPLPINTSGGQLSGGRLHGMGFLHEACVQMWGEGG
MUL_3406|M.ulcerans_Agy99           EAGPFVEGGARIARDGKLPLNTYGGQLSARRMHGYWALHEGCLQLRGDAG
Mflv_2483|M.gilvum_PYR-GCK          ESKDFLDGGHAIARDGVIPLNTHGGQLSHGRTHGMGLVHEAVSQLRGEAG
Mvan_4171|M.vanbaalenii_PYR-1       EAKDFLDGGKAIARDGVIPLNTHGGQLSHGRTHGMGLIHEAVSQLRGEAG
MMAR_4731|M.marinum_M               EAKEFLDGGKNIARDGLIPLNTHGGQLSHGRTHGMGLLHEAVTQLRGEAD
MSMEG_4814|M.smegmatis_MC2_155      EAKDFLDGGRNIARDGIIPLNTHGGQLSHGRTHGMGLIHEAVTQLRGEAG
Mb3570c|M.bovis_AF2122/97           EAKDFIADG-AIEVGGRLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TS
Rv3540c|M.tuberculosis_H37Rv        EAKDFIADG-AIEVGGRLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TS
MAB_0618|M.abscessus_ATCC_1997      EAKDFIANG-AIELGGKLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TS
                                    .   *: .*  *  .* :*:** ****.    **   : *.  *: *  .

TH_4141|M.thermoresistible__bu      DRQAPKTPEVVAVGVGGGPVAGSMLLSSR-
MAV_1865|M.avium_104                HRQAPKTPEVVAVGVGGGPVAGSMLLSSR-
MUL_3406|M.ulcerans_Agy99           QRQVPRRPEVGVVSVGGGPIAGCMLLTC--
Mflv_2483|M.gilvum_PYR-GCK          ERQVAD-ARVAVVSSGGLTPSGVMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1       ERQVDG-ARVAVVSSGGLTPSGALLLRTAT
MMAR_4731|M.marinum_M               ARQVAG-ARVGVVSSGGLTPSGVILLRADT
MSMEG_4814|M.smegmatis_MC2_155      ERQVED-ARVAVASSGGLTPSGVLLLRRDD
Mb3570c|M.bovis_AF2122/97           VNPVAGVEHVLVTAGTGVPTSGLILG----
Rv3540c|M.tuberculosis_H37Rv        VNPVAGVEHVLVTAGTGVPTSGLILG----
MAB_0618|M.abscessus_ATCC_1997      VNQVPNVEHVLVTAGTGVPTSGLILG----
                                     . .    .* ...  * . :* :*