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M. thermoresistible (build 8) TH_3582 (-)

annotation: protein of unknown function DUF35
coordinates: 1134545 - 1136176
length: 544

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3582--100% (544)protein of unknown function DUF35
M. thermoresistible (build 8)TH_4141-e-10149.74% (386) PUTATIVE DitF protein
M. thermoresistible (build 8)TH_4566-3e-9146.97% (379) PUTATIVE putative diterpenoid dioxygenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3570cltp23e-4837.47% (371) lipid-transfer protein
M. gilvum PYR-GCKMflv_2483-0.082.33% (532) hypothetical protein Mflv_2483
M. tuberculosis H37RvRv3540cltp23e-4837.47% (371) lipid-transfer protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0618-2e-5136.10% (385) lipid-transfer protein
M. marinum MMMAR_4731-0.079.03% (534) 3-ketoacyl-CoA thiolase
M. avium 104MAV_0919-0.078.28% (534) hypothetical protein MAV_0919
M. smegmatis MC2 155MSMEG_4814-0.081.99% (533) hypothetical protein MSMEG_4814
M. ulcerans Agy99MUL_3406-6e-7745.68% (370) acetyl-CoA acetyltransferase
M. vanbaalenii PYR-1Mvan_4171-0.083.83% (532) hypothetical protein Mvan_4171

CLUSTAL 2.0.9 multiple sequence alignment


TH_3582|M.thermoresistible__bu      ----VTRPLPQLTFDNEFFWTAGADGQLKILGCRDCDALIHPPQPVCRYC
MSMEG_4814|M.smegmatis_MC2_155      MSQIPGRPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRYC
Mflv_2483|M.gilvum_PYR-GCK          ---MSRLPLPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRYC
Mvan_4171|M.vanbaalenii_PYR-1       ---MSRLPLPQLTFDNEFFWKSGADGVLRIQECGDCKALIHPPQPVCRYC
MMAR_4731|M.marinum_M               MSAAPGRPLPLITDENEFFWTSGADGKLRLQECAACASLIHPPAPVCRYC
MAV_0919|M.avium_104                MSAS-GRPLPLVTEENEFFWTSGADGKLRLQECRSCASLIHPPAPVCRYC
MUL_3406|M.ulcerans_Agy99           ---------------MEAVRAAVADAGLTPADVDGIATLGDTP-------
Mb3570c|M.bovis_AF2122/97           ----------------------MLSGQAAIVGIGATDFSKNSG-------
Rv3540c|M.tuberculosis_H37Rv        ----------------------MLSGQAAIVGIGATDFSKNSG-------
MAB_0618|M.abscessus_ATCC_1997      --------------------MTGLSGRSAIAGIGATDFSKKSG-------
                                                            ..              ..        

TH_3582|M.thermoresistible__bu      RGHNLAPRVVSGQGILTGFTVNHRFGFPDLPPPYVVAQVAVAEDPRVRLT
MSMEG_4814|M.smegmatis_MC2_155      RSHDLGVRDVSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRVRLT
Mflv_2483|M.gilvum_PYR-GCK          HSHNMGPREVSGRAVLSAFTVNHRFSIPGLEAPYVVAQVAIEEDPRVRLT
Mvan_4171|M.vanbaalenii_PYR-1       HSHNMGPREVSGRAVLSAFTVNHRFSIPGLQAPYVVAQVAIEEDPRVRLT
MMAR_4731|M.marinum_M               RSRDMGVRTVSGAATLTGFTVNHRFSLPGLPAPYVIAQVAIAEDPRVRLT
MAV_0919|M.avium_104                RSRDIGVRAVSGKATLAGFTVNHRFSLPGMPAPYVIAQVAIAEDPRVRLT
MUL_3406|M.ulcerans_Agy99           ------AADVNAELQIDAPDCGTGFGTGGLLSPVMSACRAVAER---RAR
Mb3570c|M.bovis_AF2122/97           ----------RSELRLAAEAVLDALADAGLSPTDVDGLTTFTMDTN---T
Rv3540c|M.tuberculosis_H37Rv        ----------RSELRLAAEAVLDALADAGLSPTDVDGLTTFTMDTN---T
MAB_0618|M.abscessus_ATCC_1997      ----------RSELRLAAEAVLDALDDAGLSPSDVDGLVTFTMDSN---L
                                               .   : .      :   .: .. : .  :.         

TH_3582|M.thermoresistible__bu      TNIVECDPDELTLGQRVEVLFEKIEDVWLPMFRPTGQTEPADLPADEIAP
MSMEG_4814|M.smegmatis_MC2_155      TNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADTTPTPAPVEDIAP
Mflv_2483|M.gilvum_PYR-GCK          TNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEPETAALPDDEIAP
Mvan_4171|M.vanbaalenii_PYR-1       TNIIDCDPDELELGRVVEVVFEENDDVWLPLFRPTAETETAPLPEDEIAP
MMAR_4731|M.marinum_M               TNIVECDPDRLELGQTVEVVFERIEDVWLPLFRPRTDAQPRPLPVDEIAP
MAV_0919|M.avium_104                TNIVECDPDRLELGQAVEVVFEQADDVWFPLFRPSAVGEPGPLPADEIAP
MUL_3406|M.ulcerans_Agy99           HVIVYR--TIQMLGGTVALQPEQ----------------------DAPAP
Mb3570c|M.bovis_AF2122/97           EIAVARAAGIGELTFFSKIHYG----------------------------
Rv3540c|M.tuberculosis_H37Rv        EIAVARAAGIGELTFFSKIHYG----------------------------
MAB_0618|M.abscessus_ATCC_1997      ETAVARATGIGELKFFSQIGYG----------------------------
                                       :        *     :                               

TH_3582|M.thermoresistible__bu      TDFAKHVRPMLTPDKFEDRAAITGIGASRIGRRLMVPPLSLTIEACEAAV
MSMEG_4814|M.smegmatis_MC2_155      QDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAV
Mflv_2483|M.gilvum_PYR-GCK          QEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAI
Mvan_4171|M.vanbaalenii_PYR-1       QDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSPLSLTVEACEAAI
MMAR_4731|M.marinum_M               QRFGEHVRPMLTTQKFEDKVALTGIGMSTIGRRLMVAPLSLTVDACEAAV
MAV_0919|M.avium_104                ERFGDHVRPMLTTAKFEDKVALTGIGMSPIGRRLMQLPLALTVQACEAAI
MUL_3406|M.ulcerans_Agy99           -------------------------------------PLARMFDVAEGAP
Mb3570c|M.bovis_AF2122/97           -------------------------------GGAACATVQHAAMAVATGV
Rv3540c|M.tuberculosis_H37Rv        -------------------------------GGAACATVQHAAMAVATGV
MAB_0618|M.abscessus_ATCC_1997      -------------------------------GGAAAATVQQAALAVAAGV
                                                                         .:     .   . 

TH_3582|M.thermoresistible__bu      ADAGLTFDDIDGLSTYP-GIDTAGMGEGGVTALEGALGLRPTWINGGMDT
MSMEG_4814|M.smegmatis_MC2_155      ADAGLTFDDIDGLSTYP-GLDIAGMGEGGVSVLEGALGLRPTWINGGMDT
Mflv_2483|M.gilvum_PYR-GCK          ADAGLTLADIDGLSTYP-AMDAMGMGEGGCTVLEGALGIRPTWINGGMDT
Mvan_4171|M.vanbaalenii_PYR-1       ADAGLTLADIDGLSTYP-AMDAMGMGEGGVTALEGALGIRPTWINGGMDT
MMAR_4731|M.marinum_M               ADAGLTFDDIDGLSTYPGGGNLGGFGEGGVTALEAALGIRPVWHNGGIET
MAV_0919|M.avium_104                ADAGLTYADIDGLSTYPGAINVAGMGEGGVTALEAALGIRPTWHNGAMET
MUL_3406|M.ulcerans_Agy99           RPAVGPMDDIT---------------------------------------
Mb3570c|M.bovis_AF2122/97           ADVVVAYRAFNERSGMR---------------------------------
Rv3540c|M.tuberculosis_H37Rv        ADVVVAYRAFNERSGMR---------------------------------
MAB_0618|M.abscessus_ATCC_1997      AEVVVAYRAFNERSEFR---------------------------------
                                      .  .   :                                        

TH_3582|M.thermoresistible__bu      FGPGGSVIAAMMAVATGLARHVLCFRTLWEASFNQLMKEGRLAPPMGART
MSMEG_4814|M.smegmatis_MC2_155      FGPGGSVIAAMMAISAGLARHVLCFRTLWEATFGQLVKEGKMSPPMSART
Mflv_2483|M.gilvum_PYR-GCK          FGPGGSLIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGKASPPGGARV
Mvan_4171|M.vanbaalenii_PYR-1       FGPGGSVIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGRVSPPGGTRV
MMAR_4731|M.marinum_M               FGPGGSVIAAMLAVAGGLARHVLCFRTLWEATYNELMKRGKIAPPGG-RT
MAV_0919|M.avium_104                FGPGGSVIAAMLAVAGGLARHVLCFRTLWEATHTELMKQGKITPSMG-RM
MUL_3406|M.ulcerans_Agy99           -----DLIAAH---------------------------------------
Mb3570c|M.bovis_AF2122/97           --------------------------------FGQVQTRLTENADSTGVD
Rv3540c|M.tuberculosis_H37Rv        --------------------------------FGQVQTRLTENADSTGVD
MAB_0618|M.abscessus_ATCC_1997      --------------------------------FGQVMTGLSSTADSRGVE
                                                                                      

TH_3582|M.thermoresistible__bu      TSWQMPFGATSAAHTLALNAQRHFHRYGTTRETLGWIALNQRANAALNPT
MSMEG_4814|M.smegmatis_MC2_155      NSWQQPYGATSAAHTLAQNAGRHFHRYGTTRETLGWIALNQRANAALNPT
Mflv_2483|M.gilvum_PYR-GCK          NSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPT
Mvan_4171|M.vanbaalenii_PYR-1       NSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPT
MMAR_4731|M.marinum_M               TSWQYPFGATSAAHTLAINAQRHFHRYGTTKETLGWIALNQRANAELNPT
MAV_0919|M.avium_104                QGWQMPFGATSAAHTLAMNAQRHFHRYGTTKETLGWIALNQRANAELNPT
MUL_3406|M.ulcerans_Agy99           --------AYSAANWLALNCRRHMELYGTTREQLGWVALNGRRNAALNPL
Mb3570c|M.bovis_AF2122/97           NSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPK
Rv3540c|M.tuberculosis_H37Rv        NSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPK
MAB_0618|M.abscessus_ATCC_1997      YSWSYPHGLSTPAASVAMIARRYMHEYGATSADFGAVSVADRKHAATNPK
                                              :.*  :*  . *::.  *:*   :* :::  * :*  ** 

TH_3582|M.thermoresistible__bu      AVYR-DPLTMDDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAARDLR
MSMEG_4814|M.smegmatis_MC2_155      AIYR-EPLTMEDYLSARTITTPFGLYDCDVPCDGAVAVIVSAVDAARDLP
Mflv_2483|M.gilvum_PYR-GCK          AIYR-DPMTMQDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAAADAP
Mvan_4171|M.vanbaalenii_PYR-1       AIYR-DPMTMDDYLNARPITTPFGLYDCDVPCDGAVAVVVSAVDAAVDLP
MMAR_4731|M.marinum_M               AVYR-SPMTMDDYLNARPITTPFGLFDCDVPCDAAIAVIVSAVDAARDLA
MAV_0919|M.avium_104                AIYR-SPMTMEDYLGARPITTPFGLYDCDVPCDGAIAVIVSAVDAARDLA
MUL_3406|M.ulcerans_Agy99           AVYR-EPMTMADYLGARPVSTPLGLLDCDVPIDGCVAVLVSTAEYARDCP
Mb3570c|M.bovis_AF2122/97           AYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLK
Rv3540c|M.tuberculosis_H37Rv        AYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLK
MAB_0618|M.abscessus_ATCC_1997      AFFYGKPITIEDHQNSRMIADPVRLLDCCQESDGGVAIVVTTPERAKDLK
                                    * :  .*:*: *: .:* :: *. * **    *. :*::*::   * *  

TH_3582|M.thermoresistible__bu      KPPVLVEAVGT----QIIERTDWDQTTLTHEPQVLGQSAHLWSRTSLRPE
MSMEG_4814|M.smegmatis_MC2_155      RPPIRFEAVGT----QIIERLDWDQTTLTHEPQVLGQSAHMWSRTSLRPS
Mflv_2483|M.gilvum_PYR-GCK          KPPVFFEAVGT----QIIERTDWDQTTLTHEPQVLGQAAHLWTRTSLRPD
Mvan_4171|M.vanbaalenii_PYR-1       KPPVYFEAVGT----QIIERTDWDQTTLTHEPQVLGQAAHLWTRTSLRPA
MMAR_4731|M.marinum_M               KPPVLVEAVGT----QIIERIDWDQSTLTHEPQVLGQAAHVWTRTTLRPA
MAV_0919|M.avium_104                KPPVLVEAVGT----QIIERTDWDQSTLTHEPQVLGQAAHVWTRTSLRPS
MUL_3406|M.ulcerans_Agy99           PRAVRVEAIGG----SDGS-GGWFHRADYPKMAMSDAAAQMWSRTALKPA
Mb3570c|M.bovis_AF2122/97           QRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPA
Rv3540c|M.tuberculosis_H37Rv        QRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPA
MAB_0618|M.abscessus_ATCC_1997      NRPVIIEAAAQGSGEDQFTMYSYYRDELG-LPEMGLVGRQLWDQSGLTPN
                                      .: .** .     .     .: :        :   . ::* :: * * 

TH_3582|M.thermoresistible__bu      DVDVAQLYDGFTFNCLSWIEALGFCGIGEAKDFLDGGRNIARDGVLPLNT
MSMEG_4814|M.smegmatis_MC2_155      DVDVAELYDGFTFNCLSWLEGLGFCGIGEAKDFLDGGRNIARDGIIPLNT
Mflv_2483|M.gilvum_PYR-GCK          DVDVAELYDGFTFNCLSWLEALGFCGIGESKDFLDGGHAIARDGVIPLNT
Mvan_4171|M.vanbaalenii_PYR-1       DVDVAELYDGFTFNCLSWLEALGFCGIGEAKDFLDGGKAIARDGVIPLNT
MMAR_4731|M.marinum_M               DVDVAELYDGFTMNCLSWIEALGFCGIGEAKEFLDGGKNIARDGLIPLNT
MAV_0919|M.avium_104                DVDVAELYDGFSFNCLSWIEALGFCGIGEAKEFLDGGKNIARDGQLPLNT
MUL_3406|M.ulcerans_Agy99           DLEVAQLYDGFTFLTLAWLEALGICADGEAGPFVEGGARIARDGKLPLNT
Mb3570c|M.bovis_AF2122/97           DVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADG-AIEVGGRLPINT
Rv3540c|M.tuberculosis_H37Rv        DVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADG-AIEVGGRLPINT
MAB_0618|M.abscessus_ATCC_1997      DIQTAILYDHFTPYTLLQLEELGFCGKGEAKDFIANG-AIELGGKLPINT
                                    *::.* *** *:   *  :* **:*. **:  *: .*  *  .* :*:**

TH_3582|M.thermoresistible__bu      HGGQLSHGRTHGMGLIHEAVSQLRGEAGERQVPD-ARVAVASSGGLXXXR
MSMEG_4814|M.smegmatis_MC2_155      HGGQLSHGRTHGMGLIHEAVTQLRGEAGERQVED-ARVAVASSGGLTPSG
Mflv_2483|M.gilvum_PYR-GCK          HGGQLSHGRTHGMGLVHEAVSQLRGEAGERQVAD-ARVAVVSSGGLTPSG
Mvan_4171|M.vanbaalenii_PYR-1       HGGQLSHGRTHGMGLIHEAVSQLRGEAGERQVDG-ARVAVVSSGGLTPSG
MMAR_4731|M.marinum_M               HGGQLSHGRTHGMGLLHEAVTQLRGEADARQVAG-ARVGVVSSGGLTPSG
MAV_0919|M.avium_104                HGGQLSHGRTHGMGLLHEAITQLRGEAGDRQVAD-ARVGVVSSGGLTPSG
MUL_3406|M.ulcerans_Agy99           YGGQLSARRMHGYWALHEGCLQLRGDAGQRQVPRRPEVGVVSVGGGPIAG
Mb3570c|M.bovis_AF2122/97           HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-PVAGVEHVLVTAGTGVPTSG
Rv3540c|M.tuberculosis_H37Rv        HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-PVAGVEHVLVTAGTGVPTSG
MAB_0618|M.abscessus_ATCC_1997      HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-QVPNVEHVLVTAGTGVPTSG
                                    :****.    **   : *.  **** :    *    .* *.:  *     

TH_3582|M.thermoresistible__bu      WIPA----
MSMEG_4814|M.smegmatis_MC2_155      VLLLRRDD
Mflv_2483|M.gilvum_PYR-GCK          VMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1       ALLLRTAT
MMAR_4731|M.marinum_M               VILLRADT
MAV_0919|M.avium_104                VILLRADR
MUL_3406|M.ulcerans_Agy99           CMLLTC--
Mb3570c|M.bovis_AF2122/97           LILG----
Rv3540c|M.tuberculosis_H37Rv        LILG----
MAB_0618|M.abscessus_ATCC_1997      LILG----
                                     :