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VSAAPGRPLPLITDENEFFWTSGADGKLRLQECAACASLIHPPAPVCRYCRSRDMGVRTVSGAATLTGFT VNHRFSLPGLPAPYVIAQVAIAEDPRVRLTTNIVECDPDRLELGQTVEVVFERIEDVWLPLFRPRTDAQP RPLPVDEIAPQRFGEHVRPMLTTQKFEDKVALTGIGMSTIGRRLMVAPLSLTVDACEAAVADAGLTFDDI DGLSTYPGGGNLGGFGEGGVTALEAALGIRPVWHNGGIETFGPGGSVIAAMLAVAGGLARHVLCFRTLWE ATYNELMKRGKIAPPGGRTTSWQYPFGATSAAHTLAINAQRHFHRYGTTKETLGWIALNQRANAELNPTA VYRSPMTMDDYLNARPITTPFGLFDCDVPCDAAIAVIVSAVDAARDLAKPPVLVEAVGTQIIERIDWDQS TLTHEPQVLGQAAHVWTRTTLRPADVDVAELYDGFTMNCLSWIEALGFCGIGEAKEFLDGGKNIARDGLI PLNTHGGQLSHGRTHGMGLLHEAVTQLRGEADARQVAGARVGVVSSGGLTPSGVILLRADT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4731 | - | - | 100% (551) | 3-ketoacyl-CoA thiolase |
| M. marinum M | MMAR_1629 | - | 1e-81 | 44.72% (407) | acetyl-CoA acetyltransferase |
| M. marinum M | MMAR_4250 | ltp2 | 2e-46 | 33.42% (389) | keto acyl-CoA thiolase, Ltp2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 2e-47 | 34.94% (395) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2483 | - | 0.0 | 78.97% (542) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 2e-47 | 34.94% (395) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0618 | - | 3e-49 | 35.01% (397) | lipid-transfer protein |
| M. avium 104 | MAV_0919 | - | 0.0 | 87.41% (548) | hypothetical protein MAV_0919 |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 0.0 | 75.32% (551) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_3582 | - | 0.0 | 79.03% (534) | PUTATIVE protein of unknown function DUF35 |
| M. ulcerans Agy99 | MUL_3406 | - | 1e-73 | 43.95% (380) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 0.0 | 79.27% (545) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4731|M.marinum_M MSAAPGRPLPLITDENEFFWTSGADGKLRLQECAACASLIHPPAPVCRYC
MAV_0919|M.avium_104 MSAS-GRPLPLVTEENEFFWTSGADGKLRLQECRSCASLIHPPAPVCRYC
MSMEG_4814|M.smegmatis_MC2_155 MSQIPGRPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRYC
TH_3582|M.thermoresistible__bu ----VTRPLPQLTFDNEFFWTAGADGQLKILGCRDCDALIHPPQPVCRYC
Mflv_2483|M.gilvum_PYR-GCK ---MSRLPLPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRYC
Mvan_4171|M.vanbaalenii_PYR-1 ---MSRLPLPQLTFDNEFFWKSGADGVLRIQECGDCKALIHPPQPVCRYC
MUL_3406|M.ulcerans_Agy99 ---------------MEAVRAAVADAGLTPADVDGIATLGDTP-------
Mb3570c|M.bovis_AF2122/97 ----------------------MLSGQAAIVGIGATDFSKNSG-------
Rv3540c|M.tuberculosis_H37Rv ----------------------MLSGQAAIVGIGATDFSKNSG-------
MAB_0618|M.abscessus_ATCC_1997 --------------------MTGLSGRSAIAGIGATDFSKKSG-------
.. ..
MMAR_4731|M.marinum_M RSRDMGVRTVSGAATLTGFTVNHRFSLPGLPAPYVIAQVAIAEDPRVRLT
MAV_0919|M.avium_104 RSRDIGVRAVSGKATLAGFTVNHRFSLPGMPAPYVIAQVAIAEDPRVRLT
MSMEG_4814|M.smegmatis_MC2_155 RSHDLGVRDVSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRVRLT
TH_3582|M.thermoresistible__bu RGHNLAPRVVSGQGILTGFTVNHRFGFPDLPPPYVVAQVAVAEDPRVRLT
Mflv_2483|M.gilvum_PYR-GCK HSHNMGPREVSGRAVLSAFTVNHRFSIPGLEAPYVVAQVAIEEDPRVRLT
Mvan_4171|M.vanbaalenii_PYR-1 HSHNMGPREVSGRAVLSAFTVNHRFSIPGLQAPYVVAQVAIEEDPRVRLT
MUL_3406|M.ulcerans_Agy99 ------AADVNAELQIDAPDCGTGFGTGGLLSPVMSACRAVAER---RAR
Mb3570c|M.bovis_AF2122/97 ----------RSELRLAAEAVLDALADAGLSPTDVDGLTTFTMDTN---T
Rv3540c|M.tuberculosis_H37Rv ----------RSELRLAAEAVLDALADAGLSPTDVDGLTTFTMDTN---T
MAB_0618|M.abscessus_ATCC_1997 ----------RSELRLAAEAVLDALDDAGLSPSDVDGLVTFTMDSN---L
. : . : .: .. : . :.
MMAR_4731|M.marinum_M TNIVECDPDRLELGQTVEVVFERIEDVWLPLFRPRTDAQPRPLPVDEIAP
MAV_0919|M.avium_104 TNIVECDPDRLELGQAVEVVFEQADDVWFPLFRPSAVGEPGPLPADEIAP
MSMEG_4814|M.smegmatis_MC2_155 TNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADTTPTPAPVEDIAP
TH_3582|M.thermoresistible__bu TNIVECDPDELTLGQRVEVLFEKIEDVWLPMFRPTGQTEPADLPADEIAP
Mflv_2483|M.gilvum_PYR-GCK TNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEPETAALPDDEIAP
Mvan_4171|M.vanbaalenii_PYR-1 TNIIDCDPDELELGRVVEVVFEENDDVWLPLFRPTAETETAPLPEDEIAP
MUL_3406|M.ulcerans_Agy99 HVIVYR--TIQMLGGTVALQPEQ----------------------DAPAP
Mb3570c|M.bovis_AF2122/97 EIAVARAAGIGELTFFSKIHYG----------------------------
Rv3540c|M.tuberculosis_H37Rv EIAVARAAGIGELTFFSKIHYG----------------------------
MAB_0618|M.abscessus_ATCC_1997 ETAVARATGIGELKFFSQIGYG----------------------------
: * :
MMAR_4731|M.marinum_M QRFGEHVRPMLTTQKFEDKVALTGIGMSTIGRRLMVAPLSLTVDACEAAV
MAV_0919|M.avium_104 ERFGDHVRPMLTTAKFEDKVALTGIGMSPIGRRLMQLPLALTVQACEAAI
MSMEG_4814|M.smegmatis_MC2_155 QDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAV
TH_3582|M.thermoresistible__bu TDFAKHVRPMLTPDKFEDRAAITGIGASRIGRRLMVPPLSLTIEACEAAV
Mflv_2483|M.gilvum_PYR-GCK QEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAI
Mvan_4171|M.vanbaalenii_PYR-1 QDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSPLSLTVEACEAAI
MUL_3406|M.ulcerans_Agy99 -------------------------------------PLARMFDVAEGAP
Mb3570c|M.bovis_AF2122/97 -------------------------------GGAACATVQHAAMAVATGV
Rv3540c|M.tuberculosis_H37Rv -------------------------------GGAACATVQHAAMAVATGV
MAB_0618|M.abscessus_ATCC_1997 -------------------------------GGAAAATVQQAALAVAAGV
.: . .
MMAR_4731|M.marinum_M ADAGLTFDDIDGLSTYPGGGNLGGFGEGGVTALEAALGIRPVWHNGGIET
MAV_0919|M.avium_104 ADAGLTYADIDGLSTYPGAINVAGMGEGGVTALEAALGIRPTWHNGAMET
MSMEG_4814|M.smegmatis_MC2_155 ADAGLTFDDIDGLSTYP-GLDIAGMGEGGVSVLEGALGLRPTWINGGMDT
TH_3582|M.thermoresistible__bu ADAGLTFDDIDGLSTYP-GIDTAGMGEGGVTALEGALGLRPTWINGGMDT
Mflv_2483|M.gilvum_PYR-GCK ADAGLTLADIDGLSTYP-AMDAMGMGEGGCTVLEGALGIRPTWINGGMDT
Mvan_4171|M.vanbaalenii_PYR-1 ADAGLTLADIDGLSTYP-AMDAMGMGEGGVTALEGALGIRPTWINGGMDT
MUL_3406|M.ulcerans_Agy99 RPAVGPMDDIT---------------------------------------
Mb3570c|M.bovis_AF2122/97 ADVVVAYRAFNERSGMR---------------------------------
Rv3540c|M.tuberculosis_H37Rv ADVVVAYRAFNERSGMR---------------------------------
MAB_0618|M.abscessus_ATCC_1997 AEVVVAYRAFNERSEFR---------------------------------
. . :
MMAR_4731|M.marinum_M FGPGGSVIAAMLAVAGGLARHVLCFRTLWEATYNELMKRGKIAPPGG-RT
MAV_0919|M.avium_104 FGPGGSVIAAMLAVAGGLARHVLCFRTLWEATHTELMKQGKITPSMG-RM
MSMEG_4814|M.smegmatis_MC2_155 FGPGGSVIAAMMAISAGLARHVLCFRTLWEATFGQLVKEGKMSPPMSART
TH_3582|M.thermoresistible__bu FGPGGSVIAAMMAVATGLARHVLCFRTLWEASFNQLMKEGRLAPPMGART
Mflv_2483|M.gilvum_PYR-GCK FGPGGSLIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGKASPPGGARV
Mvan_4171|M.vanbaalenii_PYR-1 FGPGGSVIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGRVSPPGGTRV
MUL_3406|M.ulcerans_Agy99 -----DLIAAH---------------------------------------
Mb3570c|M.bovis_AF2122/97 --------------------------------FGQVQTRLTENADSTGVD
Rv3540c|M.tuberculosis_H37Rv --------------------------------FGQVQTRLTENADSTGVD
MAB_0618|M.abscessus_ATCC_1997 --------------------------------FGQVMTGLSSTADSRGVE
MMAR_4731|M.marinum_M TSWQYPFGATSAAHTLAINAQRHFHRYGTTKETLGWIALNQRANAELNPT
MAV_0919|M.avium_104 QGWQMPFGATSAAHTLAMNAQRHFHRYGTTKETLGWIALNQRANAELNPT
MSMEG_4814|M.smegmatis_MC2_155 NSWQQPYGATSAAHTLAQNAGRHFHRYGTTRETLGWIALNQRANAALNPT
TH_3582|M.thermoresistible__bu TSWQMPFGATSAAHTLALNAQRHFHRYGTTRETLGWIALNQRANAALNPT
Mflv_2483|M.gilvum_PYR-GCK NSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPT
Mvan_4171|M.vanbaalenii_PYR-1 NSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPT
MUL_3406|M.ulcerans_Agy99 --------AYSAANWLALNCRRHMELYGTTREQLGWVALNGRRNAALNPL
Mb3570c|M.bovis_AF2122/97 NSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPK
Rv3540c|M.tuberculosis_H37Rv NSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPK
MAB_0618|M.abscessus_ATCC_1997 YSWSYPHGLSTPAASVAMIARRYMHEYGATSADFGAVSVADRKHAATNPK
:.* :* . *::. *:* :* ::: * :* **
MMAR_4731|M.marinum_M AVYR-SPMTMDDYLNARPITTPFGLFDCDVPCDAAIAVIVSAVDAARDLA
MAV_0919|M.avium_104 AIYR-SPMTMEDYLGARPITTPFGLYDCDVPCDGAIAVIVSAVDAARDLA
MSMEG_4814|M.smegmatis_MC2_155 AIYR-EPLTMEDYLSARTITTPFGLYDCDVPCDGAVAVIVSAVDAARDLP
TH_3582|M.thermoresistible__bu AVYR-DPLTMDDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAARDLR
Mflv_2483|M.gilvum_PYR-GCK AIYR-DPMTMQDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAAADAP
Mvan_4171|M.vanbaalenii_PYR-1 AIYR-DPMTMDDYLNARPITTPFGLYDCDVPCDGAVAVVVSAVDAAVDLP
MUL_3406|M.ulcerans_Agy99 AVYR-EPMTMADYLGARPVSTPLGLLDCDVPIDGCVAVLVSTAEYARDCP
Mb3570c|M.bovis_AF2122/97 AYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLK
Rv3540c|M.tuberculosis_H37Rv AYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLK
MAB_0618|M.abscessus_ATCC_1997 AFFYGKPITIEDHQNSRMIADPVRLLDCCQESDGGVAIVVTTPERAKDLK
* : .*:*: *: .:* :: *. * ** *. :*::*:: * *
MMAR_4731|M.marinum_M KPPVLVEAVGT----QIIERIDWDQSTLTHEPQVLGQAAHVWTRTTLRPA
MAV_0919|M.avium_104 KPPVLVEAVGT----QIIERTDWDQSTLTHEPQVLGQAAHVWTRTSLRPS
MSMEG_4814|M.smegmatis_MC2_155 RPPIRFEAVGT----QIIERLDWDQTTLTHEPQVLGQSAHMWSRTSLRPS
TH_3582|M.thermoresistible__bu KPPVLVEAVGT----QIIERTDWDQTTLTHEPQVLGQSAHLWSRTSLRPE
Mflv_2483|M.gilvum_PYR-GCK KPPVFFEAVGT----QIIERTDWDQTTLTHEPQVLGQAAHLWTRTSLRPD
Mvan_4171|M.vanbaalenii_PYR-1 KPPVYFEAVGT----QIIERTDWDQTTLTHEPQVLGQAAHLWTRTSLRPA
MUL_3406|M.ulcerans_Agy99 PRAVRVEAIGG----SDGS-GGWFHRADYPKMAMSDAAAQMWSRTALKPA
Mb3570c|M.bovis_AF2122/97 QRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPA
Rv3540c|M.tuberculosis_H37Rv QRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPA
MAB_0618|M.abscessus_ATCC_1997 NRPVIIEAAAQGSGEDQFTMYSYYRDELG-LPEMGLVGRQLWDQSGLTPN
.: .** . . .: : : . ::* :: * *
MMAR_4731|M.marinum_M DVDVAELYDGFTMNCLSWIEALGFCGIGEAKEFLDGGKNIARDGLIPLNT
MAV_0919|M.avium_104 DVDVAELYDGFSFNCLSWIEALGFCGIGEAKEFLDGGKNIARDGQLPLNT
MSMEG_4814|M.smegmatis_MC2_155 DVDVAELYDGFTFNCLSWLEGLGFCGIGEAKDFLDGGRNIARDGIIPLNT
TH_3582|M.thermoresistible__bu DVDVAQLYDGFTFNCLSWIEALGFCGIGEAKDFLDGGRNIARDGVLPLNT
Mflv_2483|M.gilvum_PYR-GCK DVDVAELYDGFTFNCLSWLEALGFCGIGESKDFLDGGHAIARDGVIPLNT
Mvan_4171|M.vanbaalenii_PYR-1 DVDVAELYDGFTFNCLSWLEALGFCGIGEAKDFLDGGKAIARDGVIPLNT
MUL_3406|M.ulcerans_Agy99 DLEVAQLYDGFTFLTLAWLEALGICADGEAGPFVEGGARIARDGKLPLNT
Mb3570c|M.bovis_AF2122/97 DVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADG-AIEVGGRLPINT
Rv3540c|M.tuberculosis_H37Rv DVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADG-AIEVGGRLPINT
MAB_0618|M.abscessus_ATCC_1997 DIQTAILYDHFTPYTLLQLEELGFCGKGEAKDFIANG-AIELGGKLPINT
*::.* *** *: * :* **:*. **: *: .* * .* :*:**
MMAR_4731|M.marinum_M HGGQLSHGRTHGMGLLHEAVTQLRGEADARQVAG-ARVGVVSSGGLTPSG
MAV_0919|M.avium_104 HGGQLSHGRTHGMGLLHEAITQLRGEAGDRQVAD-ARVGVVSSGGLTPSG
MSMEG_4814|M.smegmatis_MC2_155 HGGQLSHGRTHGMGLIHEAVTQLRGEAGERQVED-ARVAVASSGGLTPSG
TH_3582|M.thermoresistible__bu HGGQLSHGRTHGMGLIHEAVSQLRGEAGERQVPD-ARVAVASSGGLXXXR
Mflv_2483|M.gilvum_PYR-GCK HGGQLSHGRTHGMGLVHEAVSQLRGEAGERQVAD-ARVAVVSSGGLTPSG
Mvan_4171|M.vanbaalenii_PYR-1 HGGQLSHGRTHGMGLIHEAVSQLRGEAGERQVDG-ARVAVVSSGGLTPSG
MUL_3406|M.ulcerans_Agy99 YGGQLSARRMHGYWALHEGCLQLRGDAGQRQVPRRPEVGVVSVGGGPIAG
Mb3570c|M.bovis_AF2122/97 HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-PVAGVEHVLVTAGTGVPTSG
Rv3540c|M.tuberculosis_H37Rv HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-PVAGVEHVLVTAGTGVPTSG
MAB_0618|M.abscessus_ATCC_1997 HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-QVPNVEHVLVTAGTGVPTSG
:****. ** : *. **** : * .* *.: *
MMAR_4731|M.marinum_M VILLRADT
MAV_0919|M.avium_104 VILLRADR
MSMEG_4814|M.smegmatis_MC2_155 VLLLRRDD
TH_3582|M.thermoresistible__bu WIPA----
Mflv_2483|M.gilvum_PYR-GCK VMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1 ALLLRTAT
MUL_3406|M.ulcerans_Agy99 CMLLTC--
Mb3570c|M.bovis_AF2122/97 LILG----
Rv3540c|M.tuberculosis_H37Rv LILG----
MAB_0618|M.abscessus_ATCC_1997 LILG----
: