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MANVTKMTGGPFDGKAVITGAGKSQVGRRLGRTGLDLTLEAVLRAIEDAGLAVDDVDGIASYPGPGVPDP GFSGATIQEVRNALGLRCRWYVSAMETAGQIGPVIEACMAVTLGLANHVVVYRSVWESTAAQQAGGGRAS VLFSGGKLPSHLEWVAPFGALSAANWLAMPAQRYMHDFGLTREQLGWIALNARRNAGLNPDAVYREPMTM DGYLGARMISEPLCLYDCDVPCDGATAVIVSRRDATKGLPRYPLTVESVGPGMFERATWDQRSDITTMAA HDSGATLWQNTTLTPADVDMAQLYDGFSFLTVMWLEALGFCEHGKVGDFIEGGERIAIDGPLPINTSGGQ LSGGRLHGMGFLHEACVQMWGEGGHRQAPKTPEVVAVGVGGGPVAGSMLLSSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1865 | - | - | 100% (403) | DitF protein |
| M. avium 104 | MAV_2586 | - | 0.0 | 90.43% (397) | DitF protein |
| M. avium 104 | MAV_0919 | - | e-100 | 49.87% (395) | hypothetical protein MAV_0919 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 3e-44 | 32.66% (398) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2483 | - | 1e-100 | 49.75% (394) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 3e-44 | 32.66% (398) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0618 | - | 4e-48 | 33.67% (398) | lipid-transfer protein |
| M. marinum M | MMAR_4731 | - | 5e-96 | 48.22% (394) | 3-ketoacyl-CoA thiolase |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 1e-101 | 48.61% (397) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_4141 | - | 0.0 | 90.18% (397) | PUTATIVE DitF protein |
| M. ulcerans Agy99 | MUL_3406 | - | 3e-85 | 46.60% (382) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 1e-101 | 50.25% (394) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1865|M.avium_104 --------------------------------------------------
TH_4141|M.thermoresistible__bu --------------------------------------------------
MUL_3406|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK MSRLP---LPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRYC
Mvan_4171|M.vanbaalenii_PYR-1 MSRLP---LPQLTFDNEFFWKSGADGVLRIQECGDCKALIHPPQPVCRYC
MMAR_4731|M.marinum_M MSAAPGRPLPLITDENEFFWTSGADGKLRLQECAACASLIHPPAPVCRYC
MSMEG_4814|M.smegmatis_MC2_155 MSQIPGRPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRYC
Mb3570c|M.bovis_AF2122/97 --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1865|M.avium_104 --------------------------------------------------
TH_4141|M.thermoresistible__bu --------------------------------------------------
MUL_3406|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK HSHNMGPREVSGRAVLSAFTVNHRFSIPGLEAPYVVAQVAIEEDPRVRLT
Mvan_4171|M.vanbaalenii_PYR-1 HSHNMGPREVSGRAVLSAFTVNHRFSIPGLQAPYVVAQVAIEEDPRVRLT
MMAR_4731|M.marinum_M RSRDMGVRTVSGAATLTGFTVNHRFSLPGLPAPYVIAQVAIAEDPRVRLT
MSMEG_4814|M.smegmatis_MC2_155 RSHDLGVRDVSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRVRLT
Mb3570c|M.bovis_AF2122/97 --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1865|M.avium_104 --------------------------------------------------
TH_4141|M.thermoresistible__bu --------------------------------------------------
MUL_3406|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK TNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEPETAALPDDEIAP
Mvan_4171|M.vanbaalenii_PYR-1 TNIIDCDPDELELGRVVEVVFEENDDVWLPLFRPTAETETAPLPEDEIAP
MMAR_4731|M.marinum_M TNIVECDPDRLELGQTVEVVFERIEDVWLPLFRPRTDAQPRPLPVDEIAP
MSMEG_4814|M.smegmatis_MC2_155 TNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADTTPTPAPVEDIAP
Mb3570c|M.bovis_AF2122/97 --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_1865|M.avium_104 ----MANVTKMTGGPFDGKAVITGAGKSQVGRRLGRTGLDLTLEAVLRAI
TH_4141|M.thermoresistible__bu ----------MSRGPFDGKAVLTGAGKSQVGRRLGRTGLDLTLEAVLRAI
MUL_3406|M.ulcerans_Agy99 ------------------------------------------MEAVRAAV
Mflv_2483|M.gilvum_PYR-GCK QEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAI
Mvan_4171|M.vanbaalenii_PYR-1 QDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSPLSLTVEACEAAI
MMAR_4731|M.marinum_M QRFGEHVRPMLTTQKFEDKVALTGIGMSTIGRRLMVAPLSLTVDACEAAV
MSMEG_4814|M.smegmatis_MC2_155 QDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAV
Mb3570c|M.bovis_AF2122/97 --------------MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDAL
Rv3540c|M.tuberculosis_H37Rv --------------MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDAL
MAB_0618|M.abscessus_ATCC_1997 ------------MTGLSGRSAIAGIGATDFSKKSGRSELRLAAEAVLDAL
:* *:
MAV_1865|M.avium_104 EDAGLAVDDVDGIASYPGPGVPDPGFSGATIQEVRNALGLRCRWYVSAME
TH_4141|M.thermoresistible__bu ADAGLDVDDIDGIASYPGPGVPDPGFSGAGIHDVRNALGLRSRWYISSME
MUL_3406|M.ulcerans_Agy99 ADAGLTPADVDGIATLG----------DTPAADVNAELQIDAPDCGTGFG
Mflv_2483|M.gilvum_PYR-GCK ADAGLTLADIDGLSTYPAMDAMG--MGEGGCTVLEGALGIRPTWINGGMD
Mvan_4171|M.vanbaalenii_PYR-1 ADAGLTLADIDGLSTYPAMDAMG--MGEGGVTALEGALGIRPTWINGGMD
MMAR_4731|M.marinum_M ADAGLTFDDIDGLSTYPGGGNLGG-FGEGGVTALEAALGIRPVWHNGGIE
MSMEG_4814|M.smegmatis_MC2_155 ADAGLTFDDIDGLSTYPGLDIAG--MGEGGVSVLEGALGLRPTWINGGMD
Mb3570c|M.bovis_AF2122/97 ADAGLSPTDVDGLTTFT--------MDTNTEIAVARAAGIGELTFFSKIH
Rv3540c|M.tuberculosis_H37Rv ADAGLSPTDVDGLTTFT--------MDTNTEIAVARAAGIGELTFFSKIH
MAB_0618|M.abscessus_ATCC_1997 DDAGLSPSDVDGLVTFT--------MDSNLETAVARATGIGELKFFSQIG
**** *:**: : : : :
MAV_1865|M.avium_104 TAG--QIGPVIEACMAVTLGLANHVVVYRSVWES--TAAQQAGGGRASVL
TH_4141|M.thermoresistible__bu TAG--QIGPVMEACMAVSLGLANHVVVFRSVWES--TAAQQGGGGRASVL
MUL_3406|M.ulcerans_Agy99 TGG--LLSPVMSACRAVAERRARHVIVYRTIQMLGGTVALQPEQDAPAPP
Mflv_2483|M.gilvum_PYR-GCK TFG--PGGSLIAAVMAVATGMARHVLCFRTLWEA--TFNQLMKEGKASPP
Mvan_4171|M.vanbaalenii_PYR-1 TFG--PGGSVIAAVMAVATGMARHVLCFRTLWEA--TFNQLMKEGRVSPP
MMAR_4731|M.marinum_M TFG--PGGSVIAAMLAVAGGLARHVLCFRTLWEA--TYNELMKRGKIAPP
MSMEG_4814|M.smegmatis_MC2_155 TFG--PGGSVIAAMMAISAGLARHVLCFRTLWEA--TFGQLVKEGKMSPP
Mb3570c|M.bovis_AF2122/97 YGGGAACATVQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENA
Rv3540c|M.tuberculosis_H37Rv YGGGAACATVQHAAMAVATGVADVVVAYRAFNERSGMRFGQVQTRLTENA
MAB_0618|M.abscessus_ATCC_1997 YGGGAAAATVQQAALAVAAGVAEVVVAYRAFNERSEFRFGQVMTGLSSTA
* ..: * *:: * *: :*:.
MAV_1865|M.avium_104 FS-------------GGKLPSHLEWVAPFGALSAANWLAMPAQRYMHDFG
TH_4141|M.thermoresistible__bu FS-------------GGKLPPHLEWVAPFGALSAANWLAMPAQRYMQEYG
MUL_3406|M.ulcerans_Agy99 LARMFDVAEGAPRPAVGPMDDITDLIAAH-AYSAANWLALNCRRHMELYG
Mflv_2483|M.gilvum_PYR-GCK GGA-----------------RVNSWQAPFGATSAAHTLALNAQRHFHRYG
Mvan_4171|M.vanbaalenii_PYR-1 GGT-----------------RVNSWQAPFGATSAAHTLALNAQRHFHRYG
MMAR_4731|M.marinum_M GG------------------RTTSWQYPFGATSAAHTLAINAQRHFHRYG
MSMEG_4814|M.smegmatis_MC2_155 MSA-----------------RTNSWQQPYGATSAAHTLAQNAGRHFHRYG
Mb3570c|M.bovis_AF2122/97 DST----------------GVDNSFSYPHGLSTPAAQVAMIARRYMHLSG
Rv3540c|M.tuberculosis_H37Rv DST----------------GVDNSFSYPHGLSTPAAQVAMIARRYMHLSG
MAB_0618|M.abscessus_ATCC_1997 DSR----------------GVEYSWSYPHGLSTPAASVAMIARRYMHEYG
. . .. :.* :* . *::. *
MAV_1865|M.avium_104 LTREQLGWIALNARRNAGLNPDAVYR-EPMTMDGYLGARMISEPLCLYDC
TH_4141|M.thermoresistible__bu LTREQLGAIAINARRNAGLNPDAIYR-EPMTMDDYLGARMISEPLCLYDC
MUL_3406|M.ulcerans_Agy99 TTREQLGWVALNGRRNAALNPLAVYR-EPMTMADYLGARPVSTPLGLLDC
Mflv_2483|M.gilvum_PYR-GCK TTKETLGWIALNQRANAALNPTAIYR-DPMTMQDYLNARPITTPFGLYDC
Mvan_4171|M.vanbaalenii_PYR-1 TTKETLGWIALNQRANAALNPTAIYR-DPMTMDDYLNARPITTPFGLYDC
MMAR_4731|M.marinum_M TTKETLGWIALNQRANAELNPTAVYR-SPMTMDDYLNARPITTPFGLFDC
MSMEG_4814|M.smegmatis_MC2_155 TTRETLGWIALNQRANAALNPTAIYR-EPLTMEDYLSARTITTPFGLYDC
Mb3570c|M.bovis_AF2122/97 ATSRDFGAVSVADRKHAANNPKAYFYGKPITIEDHQNSRWIAEPLRLLDC
Rv3540c|M.tuberculosis_H37Rv ATSRDFGAVSVADRKHAANNPKAYFYGKPITIEDHQNSRWIAEPLRLLDC
MAB_0618|M.abscessus_ATCC_1997 ATSADFGAVSVADRKHAATNPKAFFYGKPITIEDHQNSRMIADPVRLLDC
* :* ::: * :* ** * : .*:*: .: .:* :: *. * **
MAV_1865|M.avium_104 DVPCDGATAVIVSRRDATKGLPRYPLTVESVGPGMFER----ATWDQRSD
TH_4141|M.thermoresistible__bu DIPCDGATAVIVSRRDAAKGLPRHPLTVGSVGPGMFER----ATWDQRSD
MUL_3406|M.ulcerans_Agy99 DVPIDGCVAVLVSTAEYARDCPPRAVRVEAIG-GSDGS----GGWFHRAD
Mflv_2483|M.gilvum_PYR-GCK DVPCDGAVAVIVSAVDAAADAPKPPVFFEAVGTQIIER----TDWDQTTL
Mvan_4171|M.vanbaalenii_PYR-1 DVPCDGAVAVVVSAVDAAVDLPKPPVYFEAVGTQIIER----TDWDQTTL
MMAR_4731|M.marinum_M DVPCDAAIAVIVSAVDAARDLAKPPVLVEAVGTQIIER----IDWDQSTL
MSMEG_4814|M.smegmatis_MC2_155 DVPCDGAVAVIVSAVDAARDLPRPPIRFEAVGTQIIER----LDWDQTTL
Mb3570c|M.bovis_AF2122/97 CQETDGAVAIVVTSAARARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPEL
Rv3540c|M.tuberculosis_H37Rv CQETDGAVAIVVTSAARARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPEL
MAB_0618|M.abscessus_ATCC_1997 CQESDGGVAIVVTTPERAKDLKNRPVIIEAAAQGSGEDQFTMYSYYRDEL
*. *::*: : . .: . : . : :
MAV_1865|M.avium_104 ITTMAAHDSGATLWQNTTLTPADVDMAQLYDGFSFLTVMWLEALGFCEHG
TH_4141|M.thermoresistible__bu LTTMAAHDSAATLWQNTTLTPKDVDMAQIYDGFSFLTVMWLEALGFCEHG
MUL_3406|M.ulcerans_Agy99 YPKMAMSDAAAQMWSRTALKPADLEVAQLYDGFTFLTLAWLEALGICADG
Mflv_2483|M.gilvum_PYR-GCK THEPQVLGQAAHLWTRTSLRPDDVDVAELYDGFTFNCLSWLEALGFCGIG
Mvan_4171|M.vanbaalenii_PYR-1 THEPQVLGQAAHLWTRTSLRPADVDVAELYDGFTFNCLSWLEALGFCGIG
MMAR_4731|M.marinum_M THEPQVLGQAAHVWTRTTLRPADVDVAELYDGFTMNCLSWIEALGFCGIG
MSMEG_4814|M.smegmatis_MC2_155 THEPQVLGQSAHMWSRTSLRPSDVDVAELYDGFTFNCLSWLEGLGFCGIG
Mb3570c|M.bovis_AF2122/97 DGLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKG
Rv3540c|M.tuberculosis_H37Rv DGLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKG
MAB_0618|M.abscessus_ATCC_1997 G-LPEMGLVGRQLWDQSGLTPNDIQTAILYDHFTPYTLLQLEELGFCGKG
. :* .: * * *:: * :** *: : :* **:* *
MAV_1865|M.avium_104 KVGDFIEGGERIAIDGPLPINTSGGQLSGGRLHGMGFLHEACVQMWGEGG
TH_4141|M.thermoresistible__bu RVGEFIEGGQRIALDGDLPINTSGGQLSAGRLHGMGFLHEACVQMWGEGG
MUL_3406|M.ulcerans_Agy99 EAGPFVEGGARIARDGKLPLNTYGGQLSARRMHGYWALHEGCLQLRGDAG
Mflv_2483|M.gilvum_PYR-GCK ESKDFLDGGHAIARDGVIPLNTHGGQLSHGRTHGMGLVHEAVSQLRGEAG
Mvan_4171|M.vanbaalenii_PYR-1 EAKDFLDGGKAIARDGVIPLNTHGGQLSHGRTHGMGLIHEAVSQLRGEAG
MMAR_4731|M.marinum_M EAKEFLDGGKNIARDGLIPLNTHGGQLSHGRTHGMGLLHEAVTQLRGEAD
MSMEG_4814|M.smegmatis_MC2_155 EAKDFLDGGRNIARDGIIPLNTHGGQLSHGRTHGMGLIHEAVTQLRGEAG
Mb3570c|M.bovis_AF2122/97 EAKDFIADG-AIEVGGRLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TS
Rv3540c|M.tuberculosis_H37Rv EAKDFIADG-AIEVGGRLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TS
MAB_0618|M.abscessus_ATCC_1997 EAKDFIANG-AIELGGKLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TS
. *: .* * .* :*:** ****. ** : *. *: * .
MAV_1865|M.avium_104 HRQAPKTPEVVAVGVGGGPVAGSMLLSSR-
TH_4141|M.thermoresistible__bu DRQAPKTPEVVAVGVGGGPVAGSMLLSSR-
MUL_3406|M.ulcerans_Agy99 QRQVPRRPEVGVVSVGGGPIAGCMLLTC--
Mflv_2483|M.gilvum_PYR-GCK ERQVAD-ARVAVVSSGGLTPSGVMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1 ERQVDG-ARVAVVSSGGLTPSGALLLRTAT
MMAR_4731|M.marinum_M ARQVAG-ARVGVVSSGGLTPSGVILLRADT
MSMEG_4814|M.smegmatis_MC2_155 ERQVED-ARVAVASSGGLTPSGVLLLRRDD
Mb3570c|M.bovis_AF2122/97 VNPVAGVEHVLVTAGTGVPTSGLILG----
Rv3540c|M.tuberculosis_H37Rv VNPVAGVEHVLVTAGTGVPTSGLILG----
MAB_0618|M.abscessus_ATCC_1997 VNQVPNVEHVLVTAGTGVPTSGLILG----
. . .* ... * . :* :*