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SRLPLPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRYCHSHNMGPREVSGRAVLSAFTVNHR FSIPGLEAPYVVAQVAIEEDPRVRLTTNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEPETAALP DDEIAPQEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAIADAGLTLADIDGLS TYPAMDAMGMGEGGCTVLEGALGIRPTWINGGMDTFGPGGSLIAAVMAVATGMARHVLCFRTLWEATFNQ LMKEGKASPPGGARVNSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPTAIYRD PMTMQDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAAADAPKPPVFFEAVGTQIIERTDWDQTTLTH EPQVLGQAAHLWTRTSLRPDDVDVAELYDGFTFNCLSWLEALGFCGIGESKDFLDGGHAIARDGVIPLNT HGGQLSHGRTHGMGLVHEAVSQLRGEAGERQVADARVAVVSSGGLTPSGVMLLRTGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2483 | - | - | 100% (548) | hypothetical protein Mflv_2483 |
| M. gilvum PYR-GCK | Mflv_1513 | - | 1e-52 | 38.29% (397) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_0636 | - | 1e-52 | 38.23% (395) | putative nonspecific lipid-transfer protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 2e-49 | 36.02% (397) | lipid-transfer protein |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 2e-49 | 36.02% (397) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0618 | - | 6e-51 | 35.11% (393) | lipid-transfer protein |
| M. marinum M | MMAR_4731 | - | 0.0 | 78.97% (542) | 3-ketoacyl-CoA thiolase |
| M. avium 104 | MAV_0919 | - | 0.0 | 79.15% (542) | hypothetical protein MAV_0919 |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 0.0 | 78.37% (541) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_3582 | - | 0.0 | 82.33% (532) | PUTATIVE protein of unknown function DUF35 |
| M. ulcerans Agy99 | MUL_3406 | - | 5e-76 | 45.12% (379) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 0.0 | 93.96% (546) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2483|M.gilvum_PYR-GCK ---MSRLPLPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRYC
Mvan_4171|M.vanbaalenii_PYR-1 ---MSRLPLPQLTFDNEFFWKSGADGVLRIQECGDCKALIHPPQPVCRYC
MSMEG_4814|M.smegmatis_MC2_155 MSQIPGRPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRYC
TH_3582|M.thermoresistible__bu ----VTRPLPQLTFDNEFFWTAGADGQLKILGCRDCDALIHPPQPVCRYC
MMAR_4731|M.marinum_M MSAAPGRPLPLITDENEFFWTSGADGKLRLQECAACASLIHPPAPVCRYC
MAV_0919|M.avium_104 MSAS-GRPLPLVTEENEFFWTSGADGKLRLQECRSCASLIHPPAPVCRYC
MUL_3406|M.ulcerans_Agy99 ---------------MEAVRAAVADAGLTPADVDGIATLGDTP-------
Mb3570c|M.bovis_AF2122/97 ----------------------MLSGQAAIVGIGATDFSKNSG-------
Rv3540c|M.tuberculosis_H37Rv ----------------------MLSGQAAIVGIGATDFSKNSG-------
MAB_0618|M.abscessus_ATCC_1997 --------------------MTGLSGRSAIAGIGATDFSKKSG-------
.. ..
Mflv_2483|M.gilvum_PYR-GCK HSHNMGPREVSGRAVLSAFTVNHRFSIPGLEAPYVVAQVAIEEDPRVRLT
Mvan_4171|M.vanbaalenii_PYR-1 HSHNMGPREVSGRAVLSAFTVNHRFSIPGLQAPYVVAQVAIEEDPRVRLT
MSMEG_4814|M.smegmatis_MC2_155 RSHDLGVRDVSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRVRLT
TH_3582|M.thermoresistible__bu RGHNLAPRVVSGQGILTGFTVNHRFGFPDLPPPYVVAQVAVAEDPRVRLT
MMAR_4731|M.marinum_M RSRDMGVRTVSGAATLTGFTVNHRFSLPGLPAPYVIAQVAIAEDPRVRLT
MAV_0919|M.avium_104 RSRDIGVRAVSGKATLAGFTVNHRFSLPGMPAPYVIAQVAIAEDPRVRLT
MUL_3406|M.ulcerans_Agy99 ------AADVNAELQIDAPDCGTGFGTGGLLSPVMSACRAVAER---RAR
Mb3570c|M.bovis_AF2122/97 ----------RSELRLAAEAVLDALADAGLSPTDVDGLTTFTMDTN---T
Rv3540c|M.tuberculosis_H37Rv ----------RSELRLAAEAVLDALADAGLSPTDVDGLTTFTMDTN---T
MAB_0618|M.abscessus_ATCC_1997 ----------RSELRLAAEAVLDALDDAGLSPSDVDGLVTFTMDSN---L
. : . : .: .. : . :.
Mflv_2483|M.gilvum_PYR-GCK TNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEPETAALPDDEIAP
Mvan_4171|M.vanbaalenii_PYR-1 TNIIDCDPDELELGRVVEVVFEENDDVWLPLFRPTAETETAPLPEDEIAP
MSMEG_4814|M.smegmatis_MC2_155 TNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADTTPTPAPVEDIAP
TH_3582|M.thermoresistible__bu TNIVECDPDELTLGQRVEVLFEKIEDVWLPMFRPTGQTEPADLPADEIAP
MMAR_4731|M.marinum_M TNIVECDPDRLELGQTVEVVFERIEDVWLPLFRPRTDAQPRPLPVDEIAP
MAV_0919|M.avium_104 TNIVECDPDRLELGQAVEVVFEQADDVWFPLFRPSAVGEPGPLPADEIAP
MUL_3406|M.ulcerans_Agy99 HVIVYR--TIQMLGGTVALQPEQ----------------------DAPAP
Mb3570c|M.bovis_AF2122/97 EIAVARAAGIGELTFFSKIHYG----------------------------
Rv3540c|M.tuberculosis_H37Rv EIAVARAAGIGELTFFSKIHYG----------------------------
MAB_0618|M.abscessus_ATCC_1997 ETAVARATGIGELKFFSQIGYG----------------------------
: * :
Mflv_2483|M.gilvum_PYR-GCK QEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAI
Mvan_4171|M.vanbaalenii_PYR-1 QDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSPLSLTVEACEAAI
MSMEG_4814|M.smegmatis_MC2_155 QDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAV
TH_3582|M.thermoresistible__bu TDFAKHVRPMLTPDKFEDRAAITGIGASRIGRRLMVPPLSLTIEACEAAV
MMAR_4731|M.marinum_M QRFGEHVRPMLTTQKFEDKVALTGIGMSTIGRRLMVAPLSLTVDACEAAV
MAV_0919|M.avium_104 ERFGDHVRPMLTTAKFEDKVALTGIGMSPIGRRLMQLPLALTVQACEAAI
MUL_3406|M.ulcerans_Agy99 -------------------------------------PLARMFDVAEGAP
Mb3570c|M.bovis_AF2122/97 -------------------------------GGAACATVQHAAMAVATGV
Rv3540c|M.tuberculosis_H37Rv -------------------------------GGAACATVQHAAMAVATGV
MAB_0618|M.abscessus_ATCC_1997 -------------------------------GGAAAATVQQAALAVAAGV
.: . .
Mflv_2483|M.gilvum_PYR-GCK ADAGLTLADIDGLSTYP-AMDAMGMGEGGCTVLEGALGIRPTWINGGMDT
Mvan_4171|M.vanbaalenii_PYR-1 ADAGLTLADIDGLSTYP-AMDAMGMGEGGVTALEGALGIRPTWINGGMDT
MSMEG_4814|M.smegmatis_MC2_155 ADAGLTFDDIDGLSTYP-GLDIAGMGEGGVSVLEGALGLRPTWINGGMDT
TH_3582|M.thermoresistible__bu ADAGLTFDDIDGLSTYP-GIDTAGMGEGGVTALEGALGLRPTWINGGMDT
MMAR_4731|M.marinum_M ADAGLTFDDIDGLSTYPGGGNLGGFGEGGVTALEAALGIRPVWHNGGIET
MAV_0919|M.avium_104 ADAGLTYADIDGLSTYPGAINVAGMGEGGVTALEAALGIRPTWHNGAMET
MUL_3406|M.ulcerans_Agy99 RPAVGPMDDIT---------------------------------------
Mb3570c|M.bovis_AF2122/97 ADVVVAYRAFNERSGMR---------------------------------
Rv3540c|M.tuberculosis_H37Rv ADVVVAYRAFNERSGMR---------------------------------
MAB_0618|M.abscessus_ATCC_1997 AEVVVAYRAFNERSEFR---------------------------------
. . :
Mflv_2483|M.gilvum_PYR-GCK FGPGGSLIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGKASPPGGARV
Mvan_4171|M.vanbaalenii_PYR-1 FGPGGSVIAAVMAVATGMARHVLCFRTLWEATFNQLMKEGRVSPPGGTRV
MSMEG_4814|M.smegmatis_MC2_155 FGPGGSVIAAMMAISAGLARHVLCFRTLWEATFGQLVKEGKMSPPMSART
TH_3582|M.thermoresistible__bu FGPGGSVIAAMMAVATGLARHVLCFRTLWEASFNQLMKEGRLAPPMGART
MMAR_4731|M.marinum_M FGPGGSVIAAMLAVAGGLARHVLCFRTLWEATYNELMKRGKIAPPGG-RT
MAV_0919|M.avium_104 FGPGGSVIAAMLAVAGGLARHVLCFRTLWEATHTELMKQGKITPSMG-RM
MUL_3406|M.ulcerans_Agy99 -----DLIAAH---------------------------------------
Mb3570c|M.bovis_AF2122/97 --------------------------------FGQVQTRLTENADSTGVD
Rv3540c|M.tuberculosis_H37Rv --------------------------------FGQVQTRLTENADSTGVD
MAB_0618|M.abscessus_ATCC_1997 --------------------------------FGQVMTGLSSTADSRGVE
Mflv_2483|M.gilvum_PYR-GCK NSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPT
Mvan_4171|M.vanbaalenii_PYR-1 NSWQAPFGATSAAHTLALNAQRHFHRYGTTKETLGWIALNQRANAALNPT
MSMEG_4814|M.smegmatis_MC2_155 NSWQQPYGATSAAHTLAQNAGRHFHRYGTTRETLGWIALNQRANAALNPT
TH_3582|M.thermoresistible__bu TSWQMPFGATSAAHTLALNAQRHFHRYGTTRETLGWIALNQRANAALNPT
MMAR_4731|M.marinum_M TSWQYPFGATSAAHTLAINAQRHFHRYGTTKETLGWIALNQRANAELNPT
MAV_0919|M.avium_104 QGWQMPFGATSAAHTLAMNAQRHFHRYGTTKETLGWIALNQRANAELNPT
MUL_3406|M.ulcerans_Agy99 --------AYSAANWLALNCRRHMELYGTTREQLGWVALNGRRNAALNPL
Mb3570c|M.bovis_AF2122/97 NSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPK
Rv3540c|M.tuberculosis_H37Rv NSFSYPHGLSTPAAQVAMIARRYMHLSGATSRDFGAVSVADRKHAANNPK
MAB_0618|M.abscessus_ATCC_1997 YSWSYPHGLSTPAASVAMIARRYMHEYGATSADFGAVSVADRKHAATNPK
:.* :* . *::. *:* :* ::: * :* **
Mflv_2483|M.gilvum_PYR-GCK AIYR-DPMTMQDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAAADAP
Mvan_4171|M.vanbaalenii_PYR-1 AIYR-DPMTMDDYLNARPITTPFGLYDCDVPCDGAVAVVVSAVDAAVDLP
MSMEG_4814|M.smegmatis_MC2_155 AIYR-EPLTMEDYLSARTITTPFGLYDCDVPCDGAVAVIVSAVDAARDLP
TH_3582|M.thermoresistible__bu AVYR-DPLTMDDYLNARPITTPFGLYDCDVPCDGAVAVIVSAVDAARDLR
MMAR_4731|M.marinum_M AVYR-SPMTMDDYLNARPITTPFGLFDCDVPCDAAIAVIVSAVDAARDLA
MAV_0919|M.avium_104 AIYR-SPMTMEDYLGARPITTPFGLYDCDVPCDGAIAVIVSAVDAARDLA
MUL_3406|M.ulcerans_Agy99 AVYR-EPMTMADYLGARPVSTPLGLLDCDVPIDGCVAVLVSTAEYARDCP
Mb3570c|M.bovis_AF2122/97 AYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLK
Rv3540c|M.tuberculosis_H37Rv AYFYGKPITIEDHQNSRWIAEPLRLLDCCQETDGAVAIVVTSAARARDLK
MAB_0618|M.abscessus_ATCC_1997 AFFYGKPITIEDHQNSRMIADPVRLLDCCQESDGGVAIVVTTPERAKDLK
* : .*:*: *: .:* :: *. * ** *. :*::*:: * *
Mflv_2483|M.gilvum_PYR-GCK KPPVFFEAVGT----QIIERTDWDQTTLTHEPQVLGQAAHLWTRTSLRPD
Mvan_4171|M.vanbaalenii_PYR-1 KPPVYFEAVGT----QIIERTDWDQTTLTHEPQVLGQAAHLWTRTSLRPA
MSMEG_4814|M.smegmatis_MC2_155 RPPIRFEAVGT----QIIERLDWDQTTLTHEPQVLGQSAHMWSRTSLRPS
TH_3582|M.thermoresistible__bu KPPVLVEAVGT----QIIERTDWDQTTLTHEPQVLGQSAHLWSRTSLRPE
MMAR_4731|M.marinum_M KPPVLVEAVGT----QIIERIDWDQSTLTHEPQVLGQAAHVWTRTTLRPA
MAV_0919|M.avium_104 KPPVLVEAVGT----QIIERTDWDQSTLTHEPQVLGQAAHVWTRTSLRPS
MUL_3406|M.ulcerans_Agy99 PRAVRVEAIGG----SDGS-GGWFHRADYPKMAMSDAAAQMWSRTALKPA
Mb3570c|M.bovis_AF2122/97 QRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPA
Rv3540c|M.tuberculosis_H37Rv QRPVVIEAAAQGCSPDQYTMVSYYRPELDGLPEMGLVGRQLWAQSGLTPA
MAB_0618|M.abscessus_ATCC_1997 NRPVIIEAAAQGSGEDQFTMYSYYRDELG-LPEMGLVGRQLWDQSGLTPN
.: .** . . .: : : . ::* :: * *
Mflv_2483|M.gilvum_PYR-GCK DVDVAELYDGFTFNCLSWLEALGFCGIGESKDFLDGGHAIARDGVIPLNT
Mvan_4171|M.vanbaalenii_PYR-1 DVDVAELYDGFTFNCLSWLEALGFCGIGEAKDFLDGGKAIARDGVIPLNT
MSMEG_4814|M.smegmatis_MC2_155 DVDVAELYDGFTFNCLSWLEGLGFCGIGEAKDFLDGGRNIARDGIIPLNT
TH_3582|M.thermoresistible__bu DVDVAQLYDGFTFNCLSWIEALGFCGIGEAKDFLDGGRNIARDGVLPLNT
MMAR_4731|M.marinum_M DVDVAELYDGFTMNCLSWIEALGFCGIGEAKEFLDGGKNIARDGLIPLNT
MAV_0919|M.avium_104 DVDVAELYDGFSFNCLSWIEALGFCGIGEAKEFLDGGKNIARDGQLPLNT
MUL_3406|M.ulcerans_Agy99 DLEVAQLYDGFTFLTLAWLEALGICADGEAGPFVEGGARIARDGKLPLNT
Mb3570c|M.bovis_AF2122/97 DVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADG-AIEVGGRLPINT
Rv3540c|M.tuberculosis_H37Rv DVQTAVLYDHFTPFTLIQLEELGFCGKGEAKDFIADG-AIEVGGRLPINT
MAB_0618|M.abscessus_ATCC_1997 DIQTAILYDHFTPYTLLQLEELGFCGKGEAKDFIANG-AIELGGKLPINT
*::.* *** *: * :* **:*. **: *: .* * .* :*:**
Mflv_2483|M.gilvum_PYR-GCK HGGQLSHGRTHGMGLVHEAVSQLRGEAGERQVAD-ARVAVVSSGGLTPSG
Mvan_4171|M.vanbaalenii_PYR-1 HGGQLSHGRTHGMGLIHEAVSQLRGEAGERQVDG-ARVAVVSSGGLTPSG
MSMEG_4814|M.smegmatis_MC2_155 HGGQLSHGRTHGMGLIHEAVTQLRGEAGERQVED-ARVAVASSGGLTPSG
TH_3582|M.thermoresistible__bu HGGQLSHGRTHGMGLIHEAVSQLRGEAGERQVPD-ARVAVASSGGLXXXR
MMAR_4731|M.marinum_M HGGQLSHGRTHGMGLLHEAVTQLRGEADARQVAG-ARVGVVSSGGLTPSG
MAV_0919|M.avium_104 HGGQLSHGRTHGMGLLHEAITQLRGEAGDRQVAD-ARVGVVSSGGLTPSG
MUL_3406|M.ulcerans_Agy99 YGGQLSARRMHGYWALHEGCLQLRGDAGQRQVPRRPEVGVVSVGGGPIAG
Mb3570c|M.bovis_AF2122/97 HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-PVAGVEHVLVTAGTGVPTSG
Rv3540c|M.tuberculosis_H37Rv HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-PVAGVEHVLVTAGTGVPTSG
MAB_0618|M.abscessus_ATCC_1997 HGGQLGEAYIHGMNGIAEGVRQLRGTSVN-QVPNVEHVLVTAGTGVPTSG
:****. ** : *. **** : * .* *.: *
Mflv_2483|M.gilvum_PYR-GCK VMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1 ALLLRTAT
MSMEG_4814|M.smegmatis_MC2_155 VLLLRRDD
TH_3582|M.thermoresistible__bu WIPA----
MMAR_4731|M.marinum_M VILLRADT
MAV_0919|M.avium_104 VILLRADR
MUL_3406|M.ulcerans_Agy99 CMLLTC--
Mb3570c|M.bovis_AF2122/97 LILG----
Rv3540c|M.tuberculosis_H37Rv LILG----
MAB_0618|M.abscessus_ATCC_1997 LILG----
: