For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4117 | - | - | 100% (213) | putative NADH:flavin oxidoreductase/nadh oxidase |
| M. thermoresistible (build 8) | TH_2463 | - | 2e-23 | 39.13% (184) | PUTATIVE NADH:flavin oxidoreductase/nadh oxidase |
| M. thermoresistible (build 8) | TH_3970 | - | 2e-21 | 33.66% (202) | PUTATIVE putative NADH:flavin oxidoreductase/nadh oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1208c | fadH | 4e-21 | 35.14% (185) | NADPH dependent 2,4-dienoyl-CoA reductase |
| M. gilvum PYR-GCK | Mflv_4553 | - | 1e-21 | 37.10% (186) | NADH:flavin oxidoreductase/NADH oxidase |
| M. tuberculosis H37Rv | Rv1175c | fadH | 1e-21 | 35.14% (185) | NADPH dependent 2,4-dienoyl-CoA reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4635 | - | 3e-70 | 64.29% (196) | NADH:flavin oxidoreductase/NADH oxidase |
| M. marinum M | MMAR_4276 | fadH | 1e-20 | 35.23% (193) | NADPH dependent 2,4-dienoyl-CoA reductase FadH |
| M. avium 104 | MAV_4324 | - | 1e-15 | 32.11% (190) | oxidoreductase, FAD/FMN-binding superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2969 | - | 1e-26 | 37.00% (200) | NADH:flavin oxidoreductase/NADH oxidase |
| M. ulcerans Agy99 | MUL_1023 | fadH | 1e-19 | 34.72% (193) | NADPH dependent 2,4-dienoyl-CoA reductase FadH |
| M. vanbaalenii PYR-1 | Mvan_5069 | - | 1e-21 | 35.18% (199) | NADH:flavin oxidoreductase/NADH oxidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1208c|M.bovis_AF2122/97 ---MTNPYPNLLSPLDLG-FTTLRNRVVMGSMHTGLEDRAR-HIDRLADY
Rv1175c|M.tuberculosis_H37Rv ---MTNPYPNLLSPLDLG-FTTLRNRVVMGSMHTGLEDRAR-HIDRLADY
MMAR_4276|M.marinum_M ---MTSPYPNLLSPLDLG-FTTLRNRVVMGSMHTGLEDRPK-DTDRLAEY
MUL_1023|M.ulcerans_Agy99 ---MTSPYPNLLFPLDLG-FTTLRNRVVMGSMHTGLEDRPK-DTDRLAEY
TH_4117|M.thermoresistible__bu ----VTTTDTLHDPVTLPCGLVLPNRIMKAALSEVLADREHAPDARLERL
MAB_4635|M.abscessus_ATCC_1997 -------MPDIHDPLALANGQVLRNRLMKSALSEALGNAEQGPDHRLVQL
MSMEG_2969|M.smegmatis_MC2_155 ----MTNTHPALTSVRLG-GLKLDNRFAVAPMTRVSATADGAPTDAMAGY
Mvan_5069|M.vanbaalenii_PYR-1 MAFTLGAGSALLKPIQVG-GVTAENRIFMAPLTRSRADADGTPSSLAAQY
Mflv_4553|M.gilvum_PYR-GCK ---MSPNPPEPFSPVSLG-PVTLRNRVIKAATSEGR-SPHGLVTDDLIAF
MAV_4324|M.avium_104 ----MPTPPDVFSPAKLG-PITLRNRIIKSATFEAR-TPDALVTDDLIEY
. : **. ..
Mb1208c|M.bovis_AF2122/97 FAERARGGVGLIITGGYAPN-RTGWLLPFASELVTSAQARRHRRINRAVH
Rv1175c|M.tuberculosis_H37Rv FAERARGGVGLIITGGYAPN-RTGWLLPFASELVTSAQARRHRRITRAVH
MMAR_4276|M.marinum_M FAERARGGVGMLITGGYAPN-RTGWLYPFASELVTPAEARRHRRITGAVH
MUL_1023|M.ulcerans_Agy99 FAERARGGVGMLITGGYAPN-RTGWLYPFASELVTPAEARRHRRITGAVH
TH_4117|M.thermoresistible__bu YSAWARGGYGLIVTGNVMVDGSQLAEPGN-IVIEDTRHLDALTRWARTTK
MAB_4635|M.abscessus_ATCC_1997 FSRWGAGGYGLIVTGNVMVDHNHLGEPGN-VVIEDDRHLEGLSRWAKATK
MSMEG_2969|M.smegmatis_MC2_155 YAEFARGGFGLVITEGTYTDTTHSQGYLNQPGLATDAHAAGWRPVTDAVH
Mvan_5069|M.vanbaalenii_PYR-1 YAQRAEA--GLIISEATAVCEQANGAYLNTPGLYTDRQQEAWAEIASAVH
Mflv_4553|M.gilvum_PYR-GCK HRAFADGGVGMTTVAYCCVS--PQGASAPGQIVMNEAALPGLRRLTESVH
MAV_4324|M.avium_104 HRLPAAGGVGMTTVAYCAVS--PGGRTEGNGIWMRPEAVPGFRRLTDAIH
. . . *: : :
Mb1208c|M.bovis_AF2122/97 DSGA---KILLQILHAGRYAYHPLAVSASPIKAPITPFR-----------
Rv1175c|M.tuberculosis_H37Rv DSGA---KILLQILHAGRYAYHPLAVSASPIKAPITPFR-----------
MMAR_4276|M.marinum_M DADA---KILLQVLHAGRYAYHPLSVSASSIKAPINPFR-----------
MUL_1023|M.ulcerans_Agy99 DADA---KILLQVLHAGRYAYHPLSVSASSIKAPINPFR-----------
TH_4117|M.thermoresistible__bu DGNGGGVPILAQLNHPGRQANPLAFGHVPVAPSPVPLN---------FPG
MAB_4635|M.abscessus_ATCC_1997 DGGG---LIWMQVNHPGRQANPLATKHQPVAPSAVRMS---------VPG
MSMEG_2969|M.smegmatis_MC2_155 AAGV---PIVAQLMHAGALSQGNSHGVETIAPSAVAPRGTMLEEYGGAGT
Mvan_5069|M.vanbaalenii_PYR-1 GAGG---KMFVQLWHVGRMAHPEISGFENVGPSPIAAD-LVTHTPSGKKP
Mflv_4553|M.gilvum_PYR-GCK EGGA---AISAQLGHAGVVAPKKLTGVTAVAPSRFVNPTS----------
MAV_4324|M.avium_104 AEGA---AVSAQIGHAGPVANARSNKAHALAPVRFFNPIG----------
. : *: * * : .
Mb1208c|M.bovis_AF2122/97 ---PRALSARGVEATIADFARCAQLARDAGYDGVEIMGSEGYLLNQFLAP
Rv1175c|M.tuberculosis_H37Rv ---PRALSARGVEATIADFARCAQLARDAGYDGVEIMGSEGYLLNQFLAP
MMAR_4276|M.marinum_M ---PRKLTSRGVEATIADFARCAQLAQEAGYDGVEIMGSEGYLLNQFLAP
MUL_1023|M.ulcerans_Agy99 ---SRKLTSRGVEATIADFARCAQLAQEAGYDGVEIMGSEGYLLNQFLAP
TH_4117|M.thermoresistible__bu AATPRELTSAEIEDIIDRFATTAAICEAAGFDGVQIHGAHGYLITQFLSP
MAB_4635|M.abscessus_ATCC_1997 WQAPRELTDVEIEDIIDRYARTAVVADTAGFDGVQIHGAHGYLVAQFLSP
MSMEG_2969|M.smegmatis_MC2_155 WPTPREMSAADIDAAIAGFVDAAVRARAAGFDGVEIHAANGYLLDQFLTT
Mvan_5069|M.vanbaalenii_PYR-1 LPVPRALTAAEIAEIIGLFRAAARRAVDAGMDGVEIHSANGYLLHEFLSD
Mflv_4553|M.gilvum_PYR-GCK FAYCRQITRDEIRSVTAQFAAAAQIAVDAGFDAVELHFGHLYLPSSFLSP
MAV_4324|M.avium_104 MRFAKKATREDIDEVIAAHANAARLAIEAGFDAVEIHLGHNYLASSFLSP
: : : . * . ** *.*:: .. ** .**:
Mb1208c|M.bovis_AF2122/97 RTNKRTDSWGGTPANRRRFPVEIIRRSR---AAVGSDFIICYRLSMADYV
Rv1175c|M.tuberculosis_H37Rv RTNKRTDSWGGTPANRRRFPVEIIRRSR---AAVGCDFIICYRLSMADYV
MMAR_4276|M.marinum_M RTNKRTDSWGGTPAKRRRFPVEIVRRTR---AAVGPDFIICYRMSMADYV
MUL_1023|M.ulcerans_Agy99 RTNQRTDSWGGTPAKRRRFPVEIVRRTR---AAVGPDFIICYRMSMADYV
TH_4117|M.thermoresistible__bu LSNRRTDEWGGXXX--SRGCSGWPRRSR----------------------
MAB_4635|M.abscessus_ATCC_1997 NTNRRTDRWGGDAQRRMRFVLEIVRRTK---AAVSPGFAVAIKLNSADFQ
MSMEG_2969|M.smegmatis_MC2_155 YTNHRTDEYGGTVAHRIRLAAQISAAVR---TAVGADFLVGVRLSQTKVN
Mvan_5069|M.vanbaalenii_PYR-1 VVNQRTDAYGGSPQNRARFTAEVVEAVA---AEIGPE-RVGLRISP-GNN
Mflv_4553|M.gilvum_PYR-GCK LINRRKDDYGGSIDNRSRFVREIAARVR---DTVGGRIAVIAKLDMDDGL
MAV_4324|M.avium_104 LINRRNDEFGGSLQNRAKVARGMVMAVRRAVEKEGTPIAVTAKLNMADGV
*:*.* :** :
Mb1208c|M.bovis_AF2122/97 AEGQSWDEIVALATEVEGAG-ATIINSGFGWHEARVPTIVTSVPGGAFVD
Rv1175c|M.tuberculosis_H37Rv AEGQSWDEIVALATEVEGAG-ATIINSGFGWHEARVPTIVTSVPGGAFVD
MMAR_4276|M.marinum_M EGGQSWDEIVALASELETAG-ATIINSGFGWHEARIPTIVTSVPSGAFVD
MUL_1023|M.ulcerans_Agy99 EGGQSWDEIVALATELESAG-ATIINSGFGWHEARIPTIVTSVPSGAFVE
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 RGGFTEEESRGVIAALAAEG-IDLIEISG-------GTYESPAMEGRPVV
MSMEG_2969|M.smegmatis_MC2_155 DFEYRWPGGAQDAEVIFTA-----LAATG-------IDYLHIASEGRDFI
Mvan_5069|M.vanbaalenii_PYR-1 AGDMTEVDQISAYELLLCR-----IASLN-------IAYLHVVSE-----
Mflv_4553|M.gilvum_PYR-GCK PGSIWIDEALRTAALLDADGALDALELTQGSSVYKPMYLFRGDVPVREFA
MAV_4324|M.avium_104 RGGISTEESLTTAKWLESDGGLDAIELTAGSSLVNPMYLFRGDAPLKEFA
Mb1208c|M.bovis_AF2122/97 ISSAVAEHVTIPVVASNRINMPQAAERILAETQVRLISMAR---PMLSDP
Rv1175c|M.tuberculosis_H37Rv ISSAVAEHVTIPVVASNRINMPQAAERILAETQVRLISMAR---PMLSDP
MMAR_4276|M.marinum_M ISNAVAEQVSIPVMTSNRINMPQAAEQILADTDVALISMAR---PMLSDP
MUL_1023|M.ulcerans_Agy99 ISNAVAEQVSIPVMTSNRINMPQAAEQILADTDVALISMAR---PMLSDP
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 VSTSTQAREAYFLEYATTARAVAGDVPLAVTGGFRTTAAMN---EAIESG
MSMEG_2969|M.smegmatis_MC2_155 DGARLDDGRTITALARQVTGLPVIANGGMHDT-----TQAA---GVLDGG
Mvan_5069|M.vanbaalenii_PYR-1 -----PSAPAFAAIRTQWEGTLVLNTPRAVDTDF---AELE---NLATWG
Mflv_4553|M.gilvum_PYR-GCK TVMPPAMRPAVRLVGKQTMGVYPYQDLYMLDAARQFVPVMRNTKLVLLGG
MAV_4324|M.avium_104 GAFKPPLRWGMRMTGKKFLREYPYREAYLLRDAKLFRAELK-MPLILLGG
Mb1208c|M.bovis_AF2122/97 DWVLKAQSNRVDEINTCISCNQACLDHAFARKTVSCLLNPRAGRETQLVL
Rv1175c|M.tuberculosis_H37Rv DWVLKAQSNRVDEINTCISCNQACLDHAFARKTVSCLLNPRAGRETQLVL
MMAR_4276|M.marinum_M EWVLKAQSGRVDEINTCIACNQACLDHVFVKKKVSCLLNPRAGHETLLTL
MUL_1023|M.ulcerans_Agy99 EWVLKAQSGRVDEINTCIACNQACLDHVFVKKKVSCLLNPRAGHETLLTM
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 -------------ACDVIGLGRPTTVNPEAAIELLSTRRDRLTVPDAALP
MSMEG_2969|M.smegmatis_MC2_155 -------------HADVLSIGRGALANPDLPQRVSS--GAPLERFDHGML
Mvan_5069|M.vanbaalenii_PYR-1 -------------VISAAAVGRAFLANPDLVQRLTS--GAELNEPDVATF
Mflv_4553|M.gilvum_PYR-GCK ITERSHIETGLREGFDFVAMGRALLREPDLVNRIRSDPSTR---SRCTHN
MAV_4324|M.avium_104 ITNRETMDLAMAEGFEFVAMARALLAEPDLINRIAADGAAHRVHSACTHC
Mb1208c|M.bovis_AF2122/97 SPTRRARSVAVVGAGPAGLATAANAAQRGHRVTLFEANDFIGGQFDMARR
Rv1175c|M.tuberculosis_H37Rv SPTRRARSVAVVGAGPAGLATAANAAQRGHRVTLFEANDFIGGQFDMARR
MMAR_4276|M.marinum_M SPTQRARTVAVVGAGPAGLAAAVAAAQRGHRVTLFEANDFIGGQFDLARR
MUL_1023|M.ulcerans_Agy99 SPTQRARTVAVVGAGPAGLAAAVAAAQRGHRVTLFEANDFIGGQFDLARR
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 LPARLAATARAKAFLSAHELQWHGTQMHRLGAGSDPDPSIGPWITTLRLL
MSMEG_2969|M.smegmatis_MC2_155 SPMATIVNAAAWTAARHRERVPR---------------------------
Mvan_5069|M.vanbaalenii_PYR-1 YAPGPAGYIDYPTLDELAEPQSA---------------------------
Mflv_4553|M.gilvum_PYR-GCK NKCMVTVFGRTHCVLD--PDQRYGGVSPVQQRGELLA-------------
MAV_4324|M.avium_104 NQCMPTIYSRTHCVVTGAPDRHTSAAT-----------------------
Mb1208c|M.bovis_AF2122/97 IPGKEEFSETIRYFSTILAKHGVEVRLGTRVAAQELTGYDEVVLATGVAP
Rv1175c|M.tuberculosis_H37Rv IPGKEEFSETIRYFSTILAKHGVEVRLGTRVAAQELTGYDEVVLATGVAP
MMAR_4276|M.marinum_M IPGKEEFNETIRYFSTMLAKHGVDVRLATRATADELTGYDEVVLATGVAP
MUL_1023|M.ulcerans_Agy99 IPGKEEFNETIRYFSTMLAKHGVDVRLATRATADELTGYDEVVLATGVAP
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 KNNGVEAFRKRRSS------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4553|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mb1208c|M.bovis_AF2122/97 RIPAIPGIDHPMVLTYAEAITGVRPVGRTVAVVGAGGIGFDVTELLVTDS
Rv1175c|M.tuberculosis_H37Rv RIPAIPGIDHPMVLTYAEAITGVRPVGRTVAVVGAGGIGFDVTELLVTDS
MMAR_4276|M.marinum_M RIPAIPGIAHAKVLTYTEAITGAKPVGPSVAVVGAGGIGFDVTELLITES
MUL_1023|M.ulcerans_Agy99 RIPAIPGIAHAKVLTYTEAITGAKPVGPSVAVVGAGGIGFDVTELLITES
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4553|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mb1208c|M.bovis_AF2122/97 SPTLNLKEWKAEWGVADPREARGALTTPLPAPPAREVYLLQRTKGPQGKR
Rv1175c|M.tuberculosis_H37Rv SPTLNLKEWKAEWGVADPREARGALTTPLPAPPAREVYLLQRTKGPQGKR
MMAR_4276|M.marinum_M SPTLNLKEWKAEWGVVDPQEARGALTTALPTPAAREVYLLQRTKGPQGKR
MUL_1023|M.ulcerans_Agy99 SPTLNLKEWKAEWGVVDPQEARGALTTALPTPAAREVYLLQRTKGPQGKR
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4553|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mb1208c|M.bovis_AF2122/97 LGKTTGWVHRASLKAKGVHQLSGVNYEQINDDGLHISFGPKRRRPQLLAV
Rv1175c|M.tuberculosis_H37Rv LGKTTGWVHRASLKAKGVHQLSGVNYEQINDDGLHISFGPKRRRPQLLAV
MMAR_4276|M.marinum_M LGKTSGWVHRASVKAKGVHQLSGVNYERISDDGLHISFGPERQRPQLLAV
MUL_1023|M.ulcerans_Agy99 LGKTSGWVHRASVKAKGVHQLSGVNYERISDDGLHISFGPDRQRPQLLAV
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4553|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mb1208c|M.bovis_AF2122/97 DNVVVCAGQEPVRDLESELRRHGINPHISGGAAVAAELDAKRAIKQGTEL
Rv1175c|M.tuberculosis_H37Rv DNVVVCAGQEPVRDLESELRRHGINPHIIGGAAVAAELDAKRAIKQGTEL
MMAR_4276|M.marinum_M DSVVICAGQEPVRDLETDLRSNGVDPHIIGGAALAAELDAKRAIKQGTEL
MUL_1023|M.ulcerans_Agy99 DSVVICAGQEPVRDLETDLRSNGVDPHIIGGAALAAELDAKRAIKQGTEL
TH_4117|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4553|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mb1208c|M.bovis_AF2122/97 AARL
Rv1175c|M.tuberculosis_H37Rv AARL
MMAR_4276|M.marinum_M AARL
MUL_1023|M.ulcerans_Agy99 AARL
TH_4117|M.thermoresistible__bu ----
MAB_4635|M.abscessus_ATCC_1997 ----
MSMEG_2969|M.smegmatis_MC2_155 ----
Mvan_5069|M.vanbaalenii_PYR-1 ----
Mflv_4553|M.gilvum_PYR-GCK ----
MAV_4324|M.avium_104 ----