For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3970 | - | - | 100% (372) | putative NADH:flavin oxidoreductase/nadh oxidase |
| M. thermoresistible (build 8) | TH_2463 | - | 1e-29 | 32.01% (353) | PUTATIVE NADH:flavin oxidoreductase/nadh oxidase |
| M. thermoresistible (build 8) | TH_2774 | - | 3e-27 | 32.05% (337) | PUTATIVE putative NADPH dependent 2,4-dienoyl-CoA reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3394 | - | 2e-22 | 32.68% (254) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1689 | - | 3e-30 | 36.92% (214) | NADH:flavin oxidoreductase/NADH oxidase |
| M. tuberculosis H37Rv | Rv3359 | - | 2e-22 | 32.68% (254) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4635 | - | 1e-38 | 30.95% (391) | NADH:flavin oxidoreductase/NADH oxidase |
| M. marinum M | MMAR_1175 | - | 2e-22 | 26.86% (376) | oxidoreductase |
| M. avium 104 | MAV_4324 | - | 8e-21 | 27.01% (374) | oxidoreductase, FAD/FMN-binding superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2969 | - | 3e-34 | 31.34% (335) | NADH:flavin oxidoreductase/NADH oxidase |
| M. ulcerans Agy99 | MUL_1023 | fadH | 2e-21 | 32.93% (246) | NADPH dependent 2,4-dienoyl-CoA reductase FadH |
| M. vanbaalenii PYR-1 | Mvan_5069 | - | 2e-30 | 33.20% (256) | NADH:flavin oxidoreductase/NADH oxidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3394|M.bovis_AF2122/97 ----MAPGSCEAPDVFNPAKLG-PLTLRNRVIKAATFEART-PDALVTDD
Rv3359|M.tuberculosis_H37Rv ----MAPGSCEAPDVFNPAKLG-PLTLRNRVIKAATFEART-PDALVTDD
MMAR_1175|M.marinum_M ----MSP----TPDVLSPAQLG-PLTLRNRVIKAATFEART-PNALVTDD
MAV_4324|M.avium_104 ----MPT----PPDVFSPAKLG-PITLRNRIIKSATFEART-PDALVTDD
Mflv_1689|M.gilvum_PYR-GCK ----MTFTLSEQSALLKPIQVG-GTAAGNRLFMAPLTRSRADADGTPSSL
Mvan_5069|M.vanbaalenii_PYR-1 ----MAFTLGAGSALLKPIQVG-GVTAENRIFMAPLTRSRADADGTPSSL
MSMEG_2969|M.smegmatis_MC2_155 --------MTNTHPALTSVRLG-GLKLDNRFAVAPMTRVSATADGAPTDA
TH_3970|M.thermoresistible__bu MCGRRRDEMVPMTDLSAPLRFAHGPTWRNRLALAPLTNMQSNADGTLHDD
MAB_4635|M.abscessus_ATCC_1997 -----------MPDIHDPLALANGQVLRNRLMKSALSEALGNAEQGPDHR
MUL_1023|M.ulcerans_Agy99 -------MTSPYPNLLFPLDLG-FTTLRNRVVMGSMHTGLE-DRPKDTDR
. .. **. ..
Mb3394|M.bovis_AF2122/97 LIEYHRLPAAG--GVAMTTVAYCAVSPGGRTGGNQIWMRPHAVPGLRRLT
Rv3359|M.tuberculosis_H37Rv LIEYHRLPAAG--GVAMTTVAYCAVSPGGRTGGNQIWMRPHAVPGLRRLT
MMAR_1175|M.marinum_M LIEYHRQPAAG--GIAMTTVAYCAVSPGGRTSGEQIWMRREAVPGLRRLT
MAV_4324|M.avium_104 LIEYHRLPAAG--GVGMTTVAYCAVSPGGRTEGNGIWMRPEAVPGFRRLT
Mflv_1689|M.gilvum_PYR-GCK AAQYYAQRASA--GLIISEATAVCEQANGAYLNTPGLYTDRQQDKWSEIA
Mvan_5069|M.vanbaalenii_PYR-1 AAQYYAQRAEA--GLIISEATAVCEQANGAYLNTPGLYTDRQQEAWAEIA
MSMEG_2969|M.smegmatis_MC2_155 MAGYYAEFARGGFGLVITEGTYTDTTHSQGYLNQPGLATDAHAAGWRPVT
TH_3970|M.thermoresistible__bu EHHWLVRRAEGGFAMVMTCAAHVSQAG-QAFPGQLGVWHDRHLPGLTRLA
MAB_4635|M.abscessus_ATCC_1997 LVQLFSRWGAGGYGLIVTGNVMVDHNHLGEPGN-VVIEDDRHLEGLSRWA
MUL_1023|M.ulcerans_Agy99 LAEYFAERARGGVGMLITGG-YAPNRTGWLYPFASELVTPAEARRHRRIT
. . .: :: :
Mb3394|M.bovis_AF2122/97 EAIHAEGAAISAQIGHAGPVADARSNQATALAPVRFFNP----------I
Rv3359|M.tuberculosis_H37Rv EAIHAEGAAISAQIGHAGPVADARSNQATALAPVRFFNP----------I
MMAR_1175|M.marinum_M EAIHAEGAAVSAQIGHAGPVADARSNKATALAPVRFFNP----------I
MAV_4324|M.avium_104 DAIHAEGAAVSAQIGHAGPVANARSNKAHALAPVRFFNP----------I
Mflv_1689|M.gilvum_PYR-GCK SAVHRAGGKMFVQLWHVGRMAHPEISGFETVGPSPIAAD-LLTHTPTGKK
Mvan_5069|M.vanbaalenii_PYR-1 SAVHGAGGKMFVQLWHVGRMAHPEISGFENVGPSPIAAD-LVTHTPSGKK
MSMEG_2969|M.smegmatis_MC2_155 DAVHAAGVPIVAQLMHAGALSQGNSHGVETIAPSAVAPRGTMLEEYGGAG
TH_3970|M.thermoresistible__bu AGIRAAGAVATVQLHHGGRRAEARLTGLPVVAPWDDPDK-----------
MAB_4635|M.abscessus_ATCC_1997 KATKDGGGLIWMQVNHPGRQANPLATKHQPVAPSAVRMS---------VP
MUL_1023|M.ulcerans_Agy99 GAVHDADAKILLQVLHAGRYAYHPLSVSASSIKAPINPFR----------
. : . *: * * :
Mb3394|M.bovis_AF2122/97 AMRFAQKATREDIDDVLAAHAHAARLAVDAGFDAVEIHLGHNYLASAFLS
Rv3359|M.tuberculosis_H37Rv AMRFAQKATREDIDDVLAAHAHAARLAVDAGFDAVEIHLGHNYLASAFLS
MMAR_1175|M.marinum_M AMRFAKRATRDDIDDVLAAHANAARLAVEAGFDAVEIHLGHNYLASSFLS
MAV_4324|M.avium_104 GMRFAKKATREDIDEVIAAHANAARLAIEAGFDAVEIHLGHNYLASSFLS
Mflv_1689|M.gilvum_PYR-GCK PLPVPRALTTGEIAEIVGQFRAAARRAVDAGMDGVEIHSANGYLLHEFLS
Mvan_5069|M.vanbaalenii_PYR-1 PLPVPRALTAAEIAEIIGLFRAAARRAVDAGMDGVEIHSANGYLLHEFLS
MSMEG_2969|M.smegmatis_MC2_155 TWPTPREMSAADIDAAIAGFVDAAVRARAAGFDGVEIHAANGYLLDQFLT
TH_3970|M.thermoresistible__bu ---GVTALTTAQVEQVVQDFVDAAVRAEKAGFDGAEIHGAHGYLVAQFLD
MAB_4635|M.abscessus_ATCC_1997 GWQAPRELTDVEIEDIIDRYARTAVVADTAGFDGVQIHGAHGYLVAQFLS
MUL_1023|M.ulcerans_Agy99 ----SRKLTSRGVEATIADFARCAQLAQEAGYDGVEIMGSEGYLLNQFLA
: : : . * * ** *..:* ...** **
Mb3394|M.bovis_AF2122/97 PLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVR----QQVAVTAKLNMTD
Rv3359|M.tuberculosis_H37Rv PLLNRRDDEFGGSLQNRAKVARGLVMAVRRAVR----QQVAVTAKLNMTD
MMAR_1175|M.marinum_M PLINRRADEFGGSLENRAKVARGLVRAVRGALDKDGISHVAVTAKLNMAD
MAV_4324|M.avium_104 PLINRRNDEFGGSLQNRAKVARGMVMAVRRAVEKEGTP-IAVTAKLNMAD
Mflv_1689|M.gilvum_PYR-GCK DVVNQRTDAYGGSPQNRARLAAEVVEAVVAEIGPD---------------
Mvan_5069|M.vanbaalenii_PYR-1 DVVNQRTDAYGGSPQNRARFTAEVVEAVAAEIGPE---------------
MSMEG_2969|M.smegmatis_MC2_155 TYTNHRTDEYGGTVAHRIRLAAQISAAVRTAVGADF--------------
TH_3970|M.thermoresistible__bu VRHNHRTDRYGGSPENRFRIVHEIIAGIRAATSPDFQLGLRLSPE-----
MAB_4635|M.abscessus_ATCC_1997 PNTNRRTDRWGGDAQRRMRFVLEIVRRTKAAVSPGFAVAIKLNSADFQ--
MUL_1023|M.ulcerans_Agy99 PRTNQRTDSWGGTPAKRRRFPVEIVRRTRAAVGPDFIICYRMSMADYVEG
*:* * :** .* :. :
Mb3394|M.bovis_AF2122/97 GI--RGGITVDEALTTARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPV
Rv3359|M.tuberculosis_H37Rv GI--RGGITVDEALTTARWLQDDGGLDAIELTAGSSLVNPMYLFRGDAPV
MMAR_1175|M.marinum_M GV--RGGISTEESLRTAKWLEEDGGLDAIELTAGSSLVNPMYLFRGDAPV
MAV_4324|M.avium_104 GV--RGGISTEESLTTAKWLESDGGLDAIELTAGSSLVNPMYLFRGDAPL
Mflv_1689|M.gilvum_PYR-GCK ----RVGLRISPGNS-AGDMREIDDVSAYEALLCRIASLGIAYLHVLVE-
Mvan_5069|M.vanbaalenii_PYR-1 ----RVGLRISPGNN-AGDMTEVDQISAYELLLCRIASLNIAYLHVVSE-
MSMEG_2969|M.smegmatis_MC2_155 ----LVGVRLSQTKVNDFEYRWPGGAQDAEVIFTALAATGIDYLHIASEG
TH_3970|M.thermoresistible__bu ----RYGIVLDEARALAGEVLADGQLDYLDLSLWDAFKEPYEEAHRGRR-
MAB_4635|M.abscessus_ATCC_1997 ----RGGFTEEESRGVIAALAAEG-IDLIEISGGTYESPAMEGRPVVVST
MUL_1023|M.ulcerans_Agy99 GQSWDEIVALATELESAGATIINSGFGWHEARIPTIVTSVPSGAFVEISN
. . :
Mb3394|M.bovis_AF2122/97 KEFAAAFKPPLRWGIRMTGHRFFREYPYRDAYLLREARLFRAE-LTIPLI
Rv3359|M.tuberculosis_H37Rv KEFAAAFKPPLRWGIRMTGHRFFREYPYRDAYLLREARLFRAE-LTIPLI
MMAR_1175|M.marinum_M KEFAAAFKPPMRWGVRMMGKKFLREYPYRDAYLLRDARLFRSE-LSMPLI
MAV_4324|M.avium_104 KEFAGAFKPPLRWGMRMTGKKFLREYPYREAYLLRDAKLFRAE-LKMPLI
Mflv_1689|M.gilvum_PYR-GCK ---------------------------PSAPAFAAVRTQWEGT-LVLNTP
Mvan_5069|M.vanbaalenii_PYR-1 ---------------------------PSAPAFAAIRTQWEGT-LVLNTP
MSMEG_2969|M.smegmatis_MC2_155 RDFIDGARL------------------DDGRTITALARQVTGL-PVIAN-
TH_3970|M.thermoresistible__bu -------------------------------LIELFMDLPRGD-TRVGV-
MAB_4635|M.abscessus_ATCC_1997 STQAR---------------------EAYFLEYATTARAVAGD-VPLAVT
MUL_1023|M.ulcerans_Agy99 AVAEQVSIPVMTSNRINMPQAAEQILADTDVALISMARPMLSDPEWVLKA
. :
Mb3394|M.bovis_AF2122/97 LLGGITNRTTMDLAMAEGFEFVAMAR--ALLAEPDLVNRIAAEG--SQVR
Rv3359|M.tuberculosis_H37Rv LLGGITNRTTMDLAMAEGFEFVAMAR--ALLAEPDLVNRIAAEG--SQVR
MMAR_1175|M.marinum_M LLGGITNRETMDLAMAEGFEFVAMAR--ALLAEPDLINRIAAEG--NRVH
MAV_4324|M.avium_104 LLGGITNRETMDLAMAEGFEFVAMAR--ALLAEPDLINRIAADGAAHRVH
Mflv_1689|M.gilvum_PYR-GCK RTVETDFATLENLADWGVISAAAVGR--AFLANPDLIERLKLGAELNEPD
Mvan_5069|M.vanbaalenii_PYR-1 RAVDTDFAELENLATWGVISAAAVGR--AFLANPDLVQRLTSGAELNEPD
MSMEG_2969|M.smegmatis_MC2_155 -GGMHDTTQAAGVLDGGHADVLSIGR--GALANPDLPQRVSSGAPLERFD
TH_3970|M.thermoresistible__bu -AGKITDAESARRCLDSGADFVLIGK--AAIVHHDFARQVLADPAYRAAP
MAB_4635|M.abscessus_ATCC_1997 -GGFRTTAAMNEAIESGACDVIGLGR--PTTVNPEAAIELLSTRRDRLTV
MUL_1023|M.ulcerans_Agy99 QSGRVDEINTCIACNQACLDHVFVKKKVSCLLNPRAGHETLLTMSPTQRA
. : : . .
Mb3394|M.bovis_AF2122/97 SACTHCNQCMATIYRRTHCVVTGAP-------------------------
Rv3359|M.tuberculosis_H37Rv SACTHCNQCMATIYRRTHCVVTGAP-------------------------
MMAR_1175|M.marinum_M SACTHCNQCMPTIYSRTRCVVTGAPD------------------------
MAV_4324|M.avium_104 SACTHCNQCMPTIYSRTHCVVTGAPDRHTSAAT-----------------
Mflv_1689|M.gilvum_PYR-GCK VATFYAPGPDGYLDYPTLDEMVTPRSA-----------------------
Mvan_5069|M.vanbaalenii_PYR-1 VATFYAPGPAGYIDYPTLDELAEPQSA-----------------------
MSMEG_2969|M.smegmatis_MC2_155 HGMLSPMATIVNAAAWTAARHRERVPR-----------------------
TH_3970|M.thermoresistible__bu LPVSAEHLAAEAVGPRFVDYLASNWDDFVSTG------------------
MAB_4635|M.abscessus_ATCC_1997 PDAALPLPARLAATARAKAFLSAHELQWHGTQMHRLGAGSDPDPSIGPWI
MUL_1023|M.ulcerans_Agy99 RTVAVVGAGPAGLAAAVAAAQRGHRVTLFEANDFIGGQFDLARRIPGKEE
Mb3394|M.bovis_AF2122/97 --------------------------------------------------
Rv3359|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1175|M.marinum_M --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mflv_1689|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
TH_3970|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 TTLRLLKNNGVEAFRKRRSS------------------------------
MUL_1023|M.ulcerans_Agy99 FNETIRYFSTMLAKHGVDVRLATRATADELTGYDEVVLATGVAPRIPAIP
Mb3394|M.bovis_AF2122/97 --------------------------------------------------
Rv3359|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1175|M.marinum_M --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mflv_1689|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
TH_3970|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1023|M.ulcerans_Agy99 GIAHAKVLTYTEAITGAKPVGPSVAVVGAGGIGFDVTELLITESSPTLNL
Mb3394|M.bovis_AF2122/97 --------------------------------------------------
Rv3359|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1175|M.marinum_M --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mflv_1689|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
TH_3970|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1023|M.ulcerans_Agy99 KEWKAEWGVVDPQEARGALTTALPTPAAREVYLLQRTKGPQGKRLGKTSG
Mb3394|M.bovis_AF2122/97 --------------------------------------------------
Rv3359|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1175|M.marinum_M --------------------------------------------------
MAV_4324|M.avium_104 --------------------------------------------------
Mflv_1689|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 --------------------------------------------------
TH_3970|M.thermoresistible__bu --------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_1023|M.ulcerans_Agy99 WVHRASVKAKGVHQLSGVNYERISDDGLHISFGPDRQRPQLLAVDSVVIC
Mb3394|M.bovis_AF2122/97 ------------------------------------------------
Rv3359|M.tuberculosis_H37Rv ------------------------------------------------
MMAR_1175|M.marinum_M ------------------------------------------------
MAV_4324|M.avium_104 ------------------------------------------------
Mflv_1689|M.gilvum_PYR-GCK ------------------------------------------------
Mvan_5069|M.vanbaalenii_PYR-1 ------------------------------------------------
MSMEG_2969|M.smegmatis_MC2_155 ------------------------------------------------
TH_3970|M.thermoresistible__bu ------------------------------------------------
MAB_4635|M.abscessus_ATCC_1997 ------------------------------------------------
MUL_1023|M.ulcerans_Agy99 AGQEPVRDLETDLRSNGVDPHIIGGAALAAELDAKRAIKQGTELAARL