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M. leprae Br4923 MLBr_00079 (-)

annotation: putative phosphoglycerate mutase
coordinates: 99417 - 100112
length: 231

MSSRLVLLRHGQSYGNVEGRLDTRPPGASLTPFGRDQARVFAQAAGRPVLLVHSVAIRALETAAVLGAEF
DVPIREIAGIHEVQVGELENRNDDDAIAEFNAIYDRWHHGELDVPLPGGETANDVLDRYLPVLVDLRMRY
LDDGDWTGDVVVVSHGAAIRLVSAVLAEVDGRFALENRVNNAESVVLVPVTDGRWSCVRWGALTPPFYPH
LHRPDSTLVTDVVMSGRDSLG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00079--100% (231)putative phosphoglycerate mutase
M. leprae Br4923MLBr_01452-2e-1029.90% (194) putative phosphoglycerate mutase
M. leprae Br4923MLBr_01637-3e-0830.49% (164) bifunctional RNase H/acid phosphatase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3867c-5e-9471.55% (232) phosphoglycerate mutase
M. gilvum PYR-GCKMflv_1146-5e-7666.04% (212) phosphoglycerate mutase
M. tuberculosis H37RvRv3837c-5e-9471.55% (232) phosphoglycerate mutase
M. abscessus ATCC 19977MAB_0133-1e-6960.38% (212) phosphoglycerate mutase
M. marinum MMMAR_5389-6e-8366.81% (232) phosphoglycerate mutase
M. avium 104MAV_0189-4e-9267.97% (231) phosphoglycerate mutase family protein
M. smegmatis MC2 155MSMEG_6416-2e-7762.50% (232) phosphoglycerate mutase family protein
M. thermoresistible (build 8)TH_1473-3e-7259.29% (226) PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE)
M. ulcerans Agy99MUL_5010-1e-8065.52% (232) phosphoglycerate mutase
M. vanbaalenii PYR-1Mvan_5661-1e-7363.43% (216) phosphoglycerate mutase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1146|M.gilvum_PYR-GCK          -----------MTGRLVLVRHGQSHANVERRLDTRPPGAELTDLGRDQAR
Mvan_5661|M.vanbaalenii_PYR-1       -----------MSGRLVLVRHGQSHGNVARRLDTRPPGAELTDLGREQAR
Mb3867c|M.bovis_AF2122/97           -----------MSGRLVLLRHGQSYGNVERRLDTLPPGTALTPLGRDQAR
Rv3837c|M.tuberculosis_H37Rv        -----------MSGRLVLLRHGQSYGNVERRLDTLPPGTALTPLGRDQAR
MLBr_00079|M.leprae_Br4923          -----------MSSRLVLLRHGQSYGNVEGRLDTRPPGASLTPFGRDQAR
MMAR_5389|M.marinum_M               -----------MSGRLVLVRHGQSVSNVERRLDTLPPGAELTPTGRVQAQ
MUL_5010|M.ulcerans_Agy99           -----------MSGRLVLVRHGQSVSNVERRLDTLPPGAELTPTGRAQAQ
MAV_0189|M.avium_104                -----------MSGRLILVRHGQSYGNVERRLDTRPPGAELTPLGRDQAR
MSMEG_6416|M.smegmatis_MC2_155      -----------MSGRLVLVRHGQSRANVDRRLDTRPPGAELTDLGHDQAR
MAB_0133|M.abscessus_ATCC_1997      MARRDAGREAAMSGRLVLVRHGQSYGNVERRLDTKPPGAALTELGLQQAR
TH_1473|M.thermoresistible__bu      -----------MSGRLVLVRHGQSQANVERRLDTAPPGAELTDLGRQQAR
                                               *:.**:*:***** .**  **** ***: **  *  **:

Mflv_1146|M.gilvum_PYR-GCK          TFARTLAR-PAAIVTHSIATRAVQTAGHIAAEFGGALS--AGAMAFEGLH
Mvan_5661|M.vanbaalenii_PYR-1       TFARELTR-PPAMVTHSIATRAVQTAGHIYSELSGVIRSQSGTLEFEGLH
Mb3867c|M.bovis_AF2122/97           AFARSGCR-RPALLAHSVAIRAYQTAAVVAAELD------MVAHEVAGIH
Rv3837c|M.tuberculosis_H37Rv        AFARSGCR-RPALLAHSVAIRAYQTAAVVAAELD------MVAHEVAGIH
MLBr_00079|M.leprae_Br4923          VFAQAAG--RPVLLVHSVAIRALETAAVLGAEFD------VPIREIAGIH
MMAR_5389|M.marinum_M               AFARGGLI-RPAVLVHSIATRASQTAEVIAAELA------VSAHEVVGIH
MUL_5010|M.ulcerans_Agy99           AFARGGLI-RPAMLVHSIATRASQAAEVVAAVLT------VSAHEVVGIH
MAV_0189|M.avium_104                EFARRSG--RPAMLAHSVATRASQTAAVIGGQLA------LPPVELGGIH
MSMEG_6416|M.smegmatis_MC2_155      RVVTAFPR-RPALVAHSVARRAAQTASGIAGEIG------LTPQEFDGVH
MAB_0133|M.abscessus_ATCC_1997      LFAKRYEEHAPAVLVHSVAVRAVQTAAGIAEHLG------VQAEQIEGLH
TH_1473|M.thermoresistible__bu      AFARQLRR-PPGLLVHSVAVRAEQTAGEAGSHLG------QQAHVFEGIH
                                     ..       . ::.**:* ** ::*      :            . *:*

Mflv_1146|M.gilvum_PYR-GCK          EVQVGELEDRTDEAAHDEFNAVYRRWHGGELDVALPGGETAQQVLDRYVP
Mvan_5661|M.vanbaalenii_PYR-1       EVQVGHLEDRCDEAAHDEFNAIYQRWHGGELDLAMPGGESAQQVLDRYVP
Mb3867c|M.bovis_AF2122/97           EVQVGELENRNDDEAVAEFNATYSRWHRGELDVPLPGGETANDVLDRYLP
Rv3837c|M.tuberculosis_H37Rv        EVQVGELENRNDDEAVAEFNATYSRWHRGELDVPLPGGETANDVLDRYLP
MLBr_00079|M.leprae_Br4923          EVQVGELENRNDDDAIAEFNAIYDRWHHGELDVPLPGGETANDVLDRYLP
MMAR_5389|M.marinum_M               EVQVGELENRCDDEAVAEFNAIYKRWHCGELDVPLPGGESANDVLARYVP
MUL_5010|M.ulcerans_Agy99           EVQVGELENRCDDEAAAEFNAIYKRWHCGELDVPLPGGESANDVLARYVP
MAV_0189|M.avium_104                EVQVGRLENRNDDEAVAEFNAIYERWHRGELEVPLPGGETGSEVLDRYLP
MSMEG_6416|M.smegmatis_MC2_155      EVQVGELEDRNDDVAIAQFEAIYQRWHQGELEVPMPGGESAVDVLDRYVP
MAB_0133|M.abscessus_ATCC_1997      EVQAGELEDRTDLEAFAVFDRTYERWHFGDLDARMPGGESAQDVFDRYLP
TH_1473|M.thermoresistible__bu      EVQAGELENRNDDEAITEFETVYQQWHQGNLKVNMPGGENGVEVLDRYVS
                                    ***.*.**:* *  *   *:  * :** *:*.  :****.. :*: **:.

Mflv_1146|M.gilvum_PYR-GCK          VLDQLRMRYLDDETWHGDIVVVSHGAAIRLVSALLAGVDSRFAVDHHLAN
Mvan_5661|M.vanbaalenii_PYR-1       VLEQLRMRYLEDGSWHGDIVVVSHGAAIRLVAAVLAGVDSGFAVDHHLAN
Mb3867c|M.bovis_AF2122/97           VLADLRMRYLDDGDWDGDIVVVSHSAAIRLAAAVLAGVDGNFVLDNHLEN
Rv3837c|M.tuberculosis_H37Rv        VLADLRMRYLDDGDWDGDIVVVSHSAAIRLAAAVLAGVDGNFVLDNHLEN
MLBr_00079|M.leprae_Br4923          VLVDLRMRYLDDGDWTGDVVVVSHGAAIRLVSAVLAEVDGRFALENRVNN
MMAR_5389|M.marinum_M               VLNDLRMRYLDDEDRTGDLVVVSHGAAIRLAGAVLAGVDANFALDNHLDN
MUL_5010|M.ulcerans_Agy99           VLNDLRMRYLDDEDRTGDLVVVSHGAAIRPAGAVLAGVDANFALDNHLDN
MAV_0189|M.avium_104                VLTELRLRYLDDHDFHGDIVVVSHGAAIRLAAAVLAGVEADFALDHHLDN
MSMEG_6416|M.smegmatis_MC2_155      VVDHLRLNYLDDHDFDSDIVLVSHGAAIRLVAAVLAGVDGSFALEHHLAN
MAB_0133|M.abscessus_ATCC_1997      AVADLRLRHLENDASTGDVVIVSHGAAIRLVAAALAGVDPGFAVNRHLRN
TH_1473|M.thermoresistible__bu      VITQLRLHYLDNDAWTDDIVVVSHGAAIRLVAATLAGVDSTFALDRHLGN
                                    .: .**:.:*::    .*:*:***.**** ..* ** *:  *.::.:: *

Mflv_1146|M.gilvum_PYR-GCK          TESVVLAPITDGRWSCVQWGKLTPPFVGDAPVTTTAG---DAPRSADPMG
Mvan_5661|M.vanbaalenii_PYR-1       TESVVLAPVTEGRWSCVQWGKLTPPFGPEAPVVTSP----EAAQSADPMG
Mb3867c|M.bovis_AF2122/97           VESVVLAPITDGRWSCVQWGLRKPPFCPDPAEAAASPVTHAVTSSTDPMG
Rv3837c|M.tuberculosis_H37Rv        VESVVLAPITDGRWSCVQWGLRKPPFCPDPAEAAASPVTHAVTSSTDPMG
MLBr_00079|M.leprae_Br4923          AESVVLVPVTDGRWSCVRWGALTPPFYPHLHRPDSTLVTDVVMSGRDSLG
MMAR_5389|M.marinum_M               AESVVLTPITDGRWSCVRWGTKTPPFCAEVDSAAG----DLMASSGDPMG
MUL_5010|M.ulcerans_Agy99           AESVVLTPITDGRWSCVRWGTKTPPFCAEVDSAAG----DLMASSGDPMG
MAV_0189|M.avium_104                AQSVALTPITDGRWSCVRWGTLTPPFYPEAAEIPATPVADAVRSTTDPMG
MSMEG_6416|M.smegmatis_MC2_155      TESVILTPTTDGRWSCVRWATLTPPFHPEPDVQPVT---DALTS-KDPMG
MAB_0133|M.abscessus_ATCC_1997      AEAVVLAPVTDGRWSCVHWGDAVAPF-PHQEAASA----EELAQSADPMG
TH_1473|M.thermoresistible__bu      TESVVLAPITDGRWSCLQWGKESPPFYPEPDVQPV----EDALHSVDPMG
                                    .::* *.* *:*****::*.   .**  .                 *.:*