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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4035 | - | - | 100% (332) | PfkB domain protein |
| M. thermoresistible (build 8) | TH_1728 | pfkB | 1e-14 | 27.96% (279) | Probable phosphofructokinase PfkB (PHOSPHOHEXOKINASE) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2054c | pfkB | 2e-11 | 27.05% (281) | phosphofructokinase pfkB (phosphohexokinase) |
| M. gilvum PYR-GCK | Mflv_0949 | - | 1e-140 | 77.57% (321) | ribokinase-like domain-containing protein |
| M. tuberculosis H37Rv | Rv2029c | pfkB | 2e-11 | 27.05% (281) | phosphofructokinase PfkB (phosphohexokinase) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3482 | pfkB_1 | 2e-14 | 30.53% (285) | phosphofructokinase, PfkB_1 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1378 | - | 1e-13 | 30.86% (256) | 1-phosphofructokinase |
| M. ulcerans Agy99 | MUL_3559 | cbhK | 0.0001 | 22.06% (272) | carbohydrate kinase CbhK |
| M. vanbaalenii PYR-1 | Mvan_4105 | - | 2e-18 | 28.32% (286) | ribokinase-like domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4035|M.thermoresistible__bu -MTDAPPPDERPENAVVIFAPLPVLTVTIE-------DRSGEADIHVHAG
Mflv_0949|M.gilvum_PYR-GCK -MADKKP------SPIVIFAPLPVLTVTVE-------DRSGEADIHVHAG
Mb2054c|M.bovis_AF2122/97 MTEPAAWD--EGKPRIITLTMNPALDITTSVDVVRPTEKMRCGAPRYDPG
Rv2029c|M.tuberculosis_H37Rv MTEPAAWD--EGKPRIITLTMNPALDITTSVDVVRPTEKMRCGAPRYDPG
MMAR_3482|M.marinum_M MTSPADPA--VRGPQIVTLTMNPALDITTCVGVVRPTEKLRCSETRYDPG
Mvan_4105|M.vanbaalenii_PYR-1 MTDITNVRSPVSGSRIVTLTMNPALDIATSTEIVMPTEKMRCSAARYDPG
MSMEG_1378|M.smegmatis_MC2_155 --------------MIVTVTPNPSLDRTLHLPALRPGEVNRATSTMTEPS
MUL_3559|M.ulcerans_Agy99 -MTIAVTG--SIATDHLMRFPGHFSEQLLPEHLHKVSLSFLVDDLVVHRG
: . .
TH_4035|M.thermoresistible__bu GQGVWQSRMLSSLGVPVVLCAAVGGETGDVLGHLLPIPDVTVRTVPVSSR
Mflv_0949|M.gilvum_PYR-GCK GQGVWQSRMVSSLGVPVVLCSALGGETGDVLGHLLPADGVTVQTVPVSAR
Mb2054c|M.bovis_AF2122/97 GGGINVARIVHVLGGCSTALFPAGGSTGSLLMALLGDAGVPFRVIPIAAS
Rv2029c|M.tuberculosis_H37Rv GGGINVARIVHVLGGCSTALFPAGGSTGSLLMALLGDAGVPFRVIPIAAS
MMAR_3482|M.marinum_M GGGINVARIAHVLGGSVFAVFPVGGSHGAHVSKLLSEAGVAFGEIPIAAS
Mvan_4105|M.vanbaalenii_PYR-1 GGGINVARVARTLGASVVALFPAGGASGDLFADMLEAIGISAHMIPIAGS
MSMEG_1378|M.smegmatis_MC2_155 GKGVNVALALHGAGHATRAVLPVGGSVGAEIASALEGFGLDTIGVPVAGS
MUL_3559|M.ulcerans_Agy99 GVAGNMAFAIGVLGGDVALVGAAGADFADYR-DWLKAHGVNCDHVLISQT
* . : * . *. . * .: : ::
TH_4035|M.thermoresistible__bu N-GAYVHDRRTGERQVIAESPGSPLDRHELDSLYELTLTEGLKHGRVLLS
Mflv_0949|M.gilvum_PYR-GCK N-GSYVHDRRSGSREIIAEADGSPLDRHELDSLYELTLTEGLTHGRVLLS
Mb2054c|M.bovis_AF2122/97 TRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAASAAFVVAS
Rv2029c|M.tuberculosis_H37Rv TRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAASAAFVVAS
MMAR_3482|M.marinum_M TRESFTVNESSTGEQYRFVLPGPVLAPEEQAQCLQELGFAARSAQFVVAS
Mvan_4105|M.vanbaalenii_PYR-1 TRESITVNELRTQRQYRFVLPGPTLTAAEQTECLNQLREVAASADFVVAS
MSMEG_1378|M.smegmatis_MC2_155 VRSNVTLVEAD-GRSTKVNEPGPFLSEDEVDALCAAA--LADAADWVVWA
MUL_3559|M.ulcerans_Agy99 AHTARFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAVGTPELVIVAA
: . . :: :
TH_4035|M.thermoresistible__bu GPQEFGTLPAQLYRRLAGDLGGNGCQVAADLSGDRLEAVLAGG-PELIKV
Mflv_0949|M.gilvum_PYR-GCK GPQEDDVIPADLYRRLSTDLSANGCKVAADLSGERLKAVLEGK-PDLIKV
Mb2054c|M.bovis_AF2122/97 GSLPPG-VAADYYQRVADICRRSSTPLILDTSGGGLQHISSG--VFLLKA
Rv2029c|M.tuberculosis_H37Rv GSLPPG-VAADYYQRVADICRRSSTPLILDTSGGGLQHISSG--VFLLKA
MMAR_3482|M.marinum_M GSLPPG-VPADFYQRVAEACRGLGARLILDTSGGGLSHISAG--VYLLKA
Mvan_4105|M.vanbaalenii_PYR-1 GSLPPG-VSPEFYNRIADVCAQLDAPLVLDASGGGLQHLTGGN-VYLLKP
MSMEG_1378|M.smegmatis_MC2_155 GSLPAG-FAPARLAAAVDEARAAGRRVAVDASGAAMTAVLAGGSPHLIKP
MUL_3559|M.ulcerans_Agy99 NDPEAMFLHTEECRQLGLAFAADPSQQLARLSGDEIKRLING--ATYLFT
. . . ** : : * :
TH_4035|M.thermoresistible__bu SHEELLADGRAKSDDAADLVDAMRTLRDDGAGTVVVSRAGSAPALALLDG
Mflv_0949|M.gilvum_PYR-GCK SHEELLDDGRAKSEDAADLVKAMHSMRDDGAGTIVVSRSGSAPALALLDD
Mb2054c|M.bovis_AF2122/97 SVRELRECVGSELLTEPEQLAAAHELIDRGRAEVVVVSLGSQGALLATRH
Rv2029c|M.tuberculosis_H37Rv SVRELRECVGSELLTEPEQLAAAHELIDRGRAEVVVVSLGSQGALLATRH
MMAR_3482|M.marinum_M SVRELRECVGRPLVTEAEQLAAASELVETGRAEVVVVSLGSDGALLATRR
Mvan_4105|M.vanbaalenii_PYR-1 SIRELRECVRRELGSEAEQVAAARELIERGGARNVLVSLGAQGALLVTAD
MSMEG_1378|M.smegmatis_MC2_155 NLDELADATGATPATLADVVDAARSLR----VDTVLVSLGGDGAVLVTSD
MUL_3559|M.ulcerans_Agy99 NDYEWDLLLSKTGWSEADVMAQI---------GLRVTTLGPKGVDLVEPD
. * .: : : * .
TH_4035|M.thermoresistible__bu QRPGGDGSRGGSVVEIVMPTLEPADSAGAGDSMTAGIVAALAQGRPLRRA
Mflv_0949|M.gilvum_PYR-GCK ----------GDVLEVCMPTLEPADPAGAGDSMTAGMVSALALGRSLREA
Mb2054c|M.bovis_AF2122/97 -----------ASHRFSSIPMTAVSGVGAGDAMVAAITVGLSRGWSLIKS
Rv2029c|M.tuberculosis_H37Rv -----------ASHRFSSIPMTAVSGVGAGDAMVAAITVGLSRGWSLIKS
MMAR_3482|M.marinum_M -----------ARHRFRAVEMRGGSGVGAGDAMVAAITVGLARGWPLVKS
Mvan_4105|M.vanbaalenii_PYR-1 -----------GAQRYPAVEVPPGSGVGAGDAMVAGVTCGLGRGWGLPKS
MSMEG_1378|M.smegmatis_MC2_155 -----------LALHGTAPVDRVVNTVGAGDALLAGYLAACSDGP--ADA
MUL_3559|M.ulcerans_Agy99 ---------GTSIHVGVVPETSQTDPTGVGDAFRAGFLTGRSAGLNLERA
. .*.**:: *. . . * :
TH_4035|M.thermoresistible__bu LQVGAACGALNVVRHGLGTGGAEAVETLAERVELRAWEAAG---------
Mflv_0949|M.gilvum_PYR-GCK LQIGAACGALNVVRHGLGTGGARAVETLAERVELKEWKK-----------
Mb2054c|M.bovis_AF2122/97 VRLGNAAGAAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVN
Rv2029c|M.tuberculosis_H37Rv VRLGNAAGAAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVN
MMAR_3482|M.marinum_M VRLGIAAGAAMLLTPGTQACERADVERLFEHVAEPVEVA-----------
Mvan_4105|M.vanbaalenii_PYR-1 VRLGIAAGAAMLMTPGTASCTRADVERLFDRTPDPVDLT----------V
MSMEG_1378|M.smegmatis_MC2_155 LASALRFGATAVEHEGTLIG-VPDPQRPVRIGPARGDLRLG---------
MUL_3559|M.ulcerans_Agy99 AQLGSLVAVLVLESTGTQEWQWDRQVATARLAEAYGDDAANEITAVLA--
. .. : *
TH_4035|M.thermoresistible__bu -----
Mflv_0949|M.gilvum_PYR-GCK -----
Mb2054c|M.bovis_AF2122/97 PEASP
Rv2029c|M.tuberculosis_H37Rv PEASP
MMAR_3482|M.marinum_M -----
Mvan_4105|M.vanbaalenii_PYR-1 PAADR
MSMEG_1378|M.smegmatis_MC2_155 -----
MUL_3559|M.ulcerans_Agy99 -----