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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1728 | pfkB | - | 100% (313) | Probable phosphofructokinase PfkB (PHOSPHOHEXOKINASE) |
| M. thermoresistible (build 8) | TH_4035 | - | 9e-15 | 27.96% (279) | PUTATIVE PfkB domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2054c | pfkB | 3e-98 | 61.64% (305) | phosphofructokinase pfkB (phosphohexokinase) |
| M. gilvum PYR-GCK | Mflv_4987 | - | 5e-88 | 56.00% (300) | ribokinase-like domain-containing protein |
| M. tuberculosis H37Rv | Rv2029c | pfkB | 3e-98 | 61.64% (305) | phosphofructokinase PfkB (phosphohexokinase) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3482 | pfkB_1 | 6e-98 | 60.98% (305) | phosphofructokinase, PfkB_1 |
| M. avium 104 | MAV_1743 | - | 1e-06 | 24.84% (318) | kinase, pfkB family protein |
| M. smegmatis MC2 155 | MSMEG_3947 | - | 1e-103 | 61.44% (306) | 6-phosphofructokinase isozyme 2 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4105 | - | 6e-98 | 59.93% (307) | ribokinase-like domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4987|M.gilvum_PYR-GCK -------------MSGTAAIVTLTMNTALDVTADADNVV-PTEKIRCRAE
MSMEG_3947|M.smegmatis_MC2_155 MRSAAFAVGKRRMDTGRPNIVTLTMNPALDITTCADQVR-HTDKIRCGAT
Mb2054c|M.bovis_AF2122/97 ------MTEPAAWDEGKPRIITLTMNPALDITTSVDVVR-PTEKMRCGAP
Rv2029c|M.tuberculosis_H37Rv ------MTEPAAWDEGKPRIITLTMNPALDITTSVDVVR-PTEKMRCGAP
MMAR_3482|M.marinum_M ------MTSPADPAVRGPQIVTLTMNPALDITTCVGVVR-PTEKLRCSET
Mvan_4105|M.vanbaalenii_PYR-1 ----MTDITNVRSPVSGSRIVTLTMNPALDIATSTEIVM-PTEKMRCSAA
TH_1728|M.thermoresistible__bu ------------------------MNPALDISTTTDRVH-HTSKVRCHGV
MAV_1743|M.avium_104 ------------------------MN--LDLSLAVDALPRPGETVLASSL
** **:: . : ..: .
Mflv_4987|M.gilvum_PYR-GCK RYDAGGGGVNVARFAHALGAPVSAVFTAGGSTGA-RVIDLVHATGVCEI-
MSMEG_3947|M.smegmatis_MC2_155 RYDPGGGGINVARVAHVLDGPVVAVFTSGGPTGA-MVADLVRREGVAYE-
Mb2054c|M.bovis_AF2122/97 RYDPGGGGINVARIVHVLGGCSTALFPAGGSTGS-LLMALLGDAGVPFR-
Rv2029c|M.tuberculosis_H37Rv RYDPGGGGINVARIVHVLGGCSTALFPAGGSTGS-LLMALLGDAGVPFR-
MMAR_3482|M.marinum_M RYDPGGGGINVARIAHVLGGSVFAVFPVGGSHGA-HVSKLLSEAGVAFG-
Mvan_4105|M.vanbaalenii_PYR-1 RYDPGGGGINVARVARTLGASVVALFPAGGASGD-LFADMLEAIGISAH-
TH_1728|M.thermoresistible__bu RHDPGGGGINVARIAHVLGAPVTAVFPIGGHTGE-LLTDMLEHSGVSYH-
MAV_1743|M.avium_104 RQAPGGKGGNQAVAAARAGARVQFVGAVGDDAAAGQLRAHLQANGVGLDG
* .** * * * . .. : . *. . . : *:
Mflv_4987|M.gilvum_PYR-GCK PVLIEGGTRESFTVNDRASGRQYRFVLPGPVLSLGEQARCLEALRRAAGT
MSMEG_3947|M.smegmatis_MC2_155 PVEISGVTRESFTVNEGCTGKQYRFVLPGPHLTMTEQAQCVENLRRHAMS
Mb2054c|M.bovis_AF2122/97 VIPIAASTRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAAS
Rv2029c|M.tuberculosis_H37Rv VIPIAASTRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAAS
MMAR_3482|M.marinum_M EIPIAASTRESFTVNESSTGEQYRFVLPGPVLAPEEQAQCLQELGFAARS
Mvan_4105|M.vanbaalenii_PYR-1 MIPIAGSTRESITVNELRTQRQYRFVLPGPTLTAAEQTECLNQLREVAAS
TH_1728|M.thermoresistible__bu SVPIADLTRESLTVNEESTGHQYRFVLPGPFVTHEEQDAVLQRLREVAAS
MAV_1743|M.avium_104 AVEIPGPSGTAIVVVDAN-AENTIVVAPGANGRFTLND---ERARAVLAG
: * : ::.* : .: .* **. : :
Mflv_4987|M.gilvum_PYR-GCK AGIVVASGSLPPGVPPDFYQRVADICSDVGAMLVLDTSGGGLRHVTSG-V
MSMEG_3947|M.smegmatis_MC2_155 AEFVVASGSLPPGVDPRFYQQIADMCRESGVPLILDTSGGGLSHIESG-V
Mb2054c|M.bovis_AF2122/97 AAFVVASGSLPPGVAADYYQRVADICRRSSTPLILDTSGGGLQHISSG-V
Rv2029c|M.tuberculosis_H37Rv AAFVVASGSLPPGVAADYYQRVADICRRSSTPLILDTSGGGLQHISSG-V
MMAR_3482|M.marinum_M AQFVVASGSLPPGVPADFYQRVAEACRGLGARLILDTSGGGLSHISAG-V
Mvan_4105|M.vanbaalenii_PYR-1 ADFVVASGSLPPGVSPEFYNRIADVCAQLDAPLVLDASGGGLQHLTGGNV
TH_1728|M.thermoresistible__bu AQFLVASGSLPPGVPADFYQRVADLCRELGVLLILDSSGGGLTQVRYG-A
MAV_1743|M.avium_104 CDVMLTQLEIPVATAVAAAR----HARSGGAVVVVNASPAGRD-------
. .:::. .:* .. . . .. :::::* .*
Mflv_4987|M.gilvum_PYR-GCK HLLKPSIRELRECLDRPLHTEPEQIAAARELIDRGAAKVVVVSLGADGAL
MSMEG_3947|M.smegmatis_MC2_155 FVLKPSLRELRECTGKELTTEREQVAAARDLIDRGVTDVVIVSLGGDGAL
Mb2054c|M.bovis_AF2122/97 FLLKASVRELRECVGSELLTEPEQLAAAHELIDRGRAEVVVVSLGSQGAL
Rv2029c|M.tuberculosis_H37Rv FLLKASVRELRECVGSELLTEPEQLAAAHELIDRGRAEVVVVSLGSQGAL
MMAR_3482|M.marinum_M YLLKASVRELRECVGRPLVTEAEQLAAASELVETGRAEVVVVSLGSDGAL
Mvan_4105|M.vanbaalenii_PYR-1 YLLKPSIRELRECVRRELGSEAEQVAAARELIERGGARNVLVSLGAQGAL
TH_1728|M.thermoresistible__bu FLVKPSKRELREYVGRDIPTTADQIAAAHELIDRGVTQAVVVSLGADGAL
MAV_1743|M.avium_104 ---PDSLSELAAAADVVITNEEE----ASEWPWR--PRHLVVTLGSHGAR
* ** : . : * : . ::*:**..**
Mflv_4987|M.gilvum_PYR-GCK LVTPDDSERLSAVPMTSV-SCVGAGDALVAGVAVGLARRWPLGR----AV
MSMEG_3947|M.smegmatis_MC2_155 MVTARQSQRFKAVPVASG-SGVGAGDAMVAAITVGLSRGWPLPK----SV
Mb2054c|M.bovis_AF2122/97 LATRHASHRFSSIPMTAV-SGVGAGDAMVAAITVGLSRGWSLIK----SV
Rv2029c|M.tuberculosis_H37Rv LATRHASHRFSSIPMTAV-SGVGAGDAMVAAITVGLSRGWSLIK----SV
MMAR_3482|M.marinum_M LATRRARHRFRAVEMRGG-SGVGAGDAMVAAITVGLARGWPLVK----SV
Mvan_4105|M.vanbaalenii_PYR-1 LVTADGAQRYPAVEVPPG-SGVGAGDAMVAGVTCGLGRGWGLPK----SV
TH_1728|M.thermoresistible__bu LATADVDQKFEAIDVPVVLSGVGAGDAMVAGITVALSRRWSLSD----AV
MAV_1743|M.avium_104 YVGADGEYSVPSPDVDAV-DTTGAGDVFAGVLAANWPLEPGSPDQRRLAL
. : : . .****.:.. :: ::
Mflv_4987|M.gilvum_PYR-GCK RFGIAAASAKLQTPGTAAFHRDDVERYFVTQAAHSEA-------------
MSMEG_3947|M.smegmatis_MC2_155 RYGIAAGAAMLLTPGTAVCRRAEVERLFALAAEPEDLTSGW---------
Mb2054c|M.bovis_AF2122/97 RLGNAAGAAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVNP
Rv2029c|M.tuberculosis_H37Rv RLGNAAGAAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVNP
MMAR_3482|M.marinum_M RLGIAAGAAMLLTPGTQACERADVERLFEHVAEPVEVA------------
Mvan_4105|M.vanbaalenii_PYR-1 RLGIAAGAAMLMTPGTASCTRADVERLFDRTPDPVDLTVPAADR------
TH_1728|M.thermoresistible__bu RYGVATGSAMLLTPGTAPCRPEDVERLFAQAAPPVDVTRSPARN------
MAV_1743|M.avium_104 RRACAAGALATLVPGAGDCAPRAEEIERALRGKS----------------
* . *:.: .**: *
Mflv_4987|M.gilvum_PYR-GCK ----
MSMEG_3947|M.smegmatis_MC2_155 ----
Mb2054c|M.bovis_AF2122/97 EASP
Rv2029c|M.tuberculosis_H37Rv EASP
MMAR_3482|M.marinum_M ----
Mvan_4105|M.vanbaalenii_PYR-1 ----
TH_1728|M.thermoresistible__bu ----
MAV_1743|M.avium_104 ----