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MTEPAAWDEGKPRIITLTMNPALDITTSVDVVRPTEKMRCGAPRYDPGGGGINVARIVHVLGGCSTALFP AGGSTGSLLMALLGDAGVPFRVIPIAASTRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAA SAAFVVASGSLPPGVAADYYQRVADICRRSSTPLILDTSGGGLQHISSGVFLLKASVRELRECVGSELLT EPEQLAAAHELIDRGRAEVVVVSLGSQGALLATRHASHRFSSIPMTAVSGVGAGDAMVAAITVGLSRGWS LIKSVRLGNAAGAAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVNPEASP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2054c | pfkB | - | 100% (339) | phosphofructokinase pfkB (phosphohexokinase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4987 | - | 1e-100 | 60.26% (312) | ribokinase-like domain-containing protein |
| M. tuberculosis H37Rv | Rv2029c | pfkB | 0.0 | 100.00% (339) | phosphofructokinase PfkB (phosphohexokinase) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3482 | pfkB_1 | 1e-126 | 73.29% (322) | phosphofructokinase, PfkB_1 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3947 | - | 1e-116 | 66.03% (315) | 6-phosphofructokinase isozyme 2 |
| M. thermoresistible (build 8) | TH_1728 | pfkB | 3e-98 | 61.64% (305) | Probable phosphofructokinase PfkB (PHOSPHOHEXOKINASE) |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4105 | - | 1e-110 | 63.34% (311) | ribokinase-like domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2054c|M.bovis_AF2122/97 ------MTEPAAWDEGKPRIITLTMNPALDITTSVDVVRPTEKMRCGAPR
Rv2029c|M.tuberculosis_H37Rv ------MTEPAAWDEGKPRIITLTMNPALDITTSVDVVRPTEKMRCGAPR
MMAR_3482|M.marinum_M ------MTSPADPAVRGPQIVTLTMNPALDITTCVGVVRPTEKLRCSETR
Mflv_4987|M.gilvum_PYR-GCK -------------MSGTAAIVTLTMNTALDVTADADNVVPTEKIRCRAER
MSMEG_3947|M.smegmatis_MC2_155 MRSAAFAVGKRRMDTGRPNIVTLTMNPALDITTCADQVRHTDKIRCGATR
TH_1728|M.thermoresistible__bu ------------------------MNPALDISTTTDRVHHTSKVRCHGVR
Mvan_4105|M.vanbaalenii_PYR-1 ----MTDITNVRSPVSGSRIVTLTMNPALDIATSTEIVMPTEKMRCSAAR
**.***::: . * *.*:** *
Mb2054c|M.bovis_AF2122/97 YDPGGGGINVARIVHVLGGCSTALFPAGGSTGSLLMALLGDAGVPFRVIP
Rv2029c|M.tuberculosis_H37Rv YDPGGGGINVARIVHVLGGCSTALFPAGGSTGSLLMALLGDAGVPFRVIP
MMAR_3482|M.marinum_M YDPGGGGINVARIAHVLGGSVFAVFPVGGSHGAHVSKLLSEAGVAFGEIP
Mflv_4987|M.gilvum_PYR-GCK YDAGGGGVNVARFAHALGAPVSAVFTAGGSTGARVIDLVHATGVCEIPVL
MSMEG_3947|M.smegmatis_MC2_155 YDPGGGGINVARVAHVLDGPVVAVFTSGGPTGAMVADLVRREGVAYEPVE
TH_1728|M.thermoresistible__bu HDPGGGGINVARIAHVLGAPVTAVFPIGGHTGELLTDMLEHSGVSYHSVP
Mvan_4105|M.vanbaalenii_PYR-1 YDPGGGGINVARVARTLGASVVALFPAGGASGDLFADMLEAIGISAHMIP
:*.****:****..:.*.. *:*. ** * . :: *: :
Mb2054c|M.bovis_AF2122/97 IAASTRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAASAAF
Rv2029c|M.tuberculosis_H37Rv IAASTRESFTVNESRTAKQYRFVLPGPSLTVAEQEQCLDELRGAAASAAF
MMAR_3482|M.marinum_M IAASTRESFTVNESSTGEQYRFVLPGPVLAPEEQAQCLQELGFAARSAQF
Mflv_4987|M.gilvum_PYR-GCK IEGGTRESFTVNDRASGRQYRFVLPGPVLSLGEQARCLEALRRAAGTAGI
MSMEG_3947|M.smegmatis_MC2_155 ISGVTRESFTVNEGCTGKQYRFVLPGPHLTMTEQAQCVENLRRHAMSAEF
TH_1728|M.thermoresistible__bu IADLTRESLTVNEESTGHQYRFVLPGPFVTHEEQDAVLQRLREVAASAQF
Mvan_4105|M.vanbaalenii_PYR-1 IAGSTRESITVNELRTQRQYRFVLPGPTLTAAEQTECLNQLREVAASADF
* ****:***: : .********* :: ** :: * * :* :
Mb2054c|M.bovis_AF2122/97 VVASGSLPPGVAADYYQRVADICRRSSTPLILDTSGGGLQHISSG-VFLL
Rv2029c|M.tuberculosis_H37Rv VVASGSLPPGVAADYYQRVADICRRSSTPLILDTSGGGLQHISSG-VFLL
MMAR_3482|M.marinum_M VVASGSLPPGVPADFYQRVAEACRGLGARLILDTSGGGLSHISAG-VYLL
Mflv_4987|M.gilvum_PYR-GCK VVASGSLPPGVPPDFYQRVADICSDVGAMLVLDTSGGGLRHVTSG-VHLL
MSMEG_3947|M.smegmatis_MC2_155 VVASGSLPPGVDPRFYQQIADMCRESGVPLILDTSGGGLSHIESG-VFVL
TH_1728|M.thermoresistible__bu LVASGSLPPGVPADFYQRVADLCRELGVLLILDSSGGGLTQVRYG-AFLV
Mvan_4105|M.vanbaalenii_PYR-1 VVASGSLPPGVSPEFYNRIADVCAQLDAPLVLDASGGGLQHLTGGNVYLL
:********** . :*:::*: * .. *:**:***** :: * ..::
Mb2054c|M.bovis_AF2122/97 KASVRELRECVGSELLTEPEQLAAAHELIDRGRAEVVVVSLGSQGALLAT
Rv2029c|M.tuberculosis_H37Rv KASVRELRECVGSELLTEPEQLAAAHELIDRGRAEVVVVSLGSQGALLAT
MMAR_3482|M.marinum_M KASVRELRECVGRPLVTEAEQLAAASELVETGRAEVVVVSLGSDGALLAT
Mflv_4987|M.gilvum_PYR-GCK KPSIRELRECLDRPLHTEPEQIAAARELIDRGAAKVVVVSLGADGALLVT
MSMEG_3947|M.smegmatis_MC2_155 KPSLRELRECTGKELTTEREQVAAARDLIDRGVTDVVIVSLGGDGALMVT
TH_1728|M.thermoresistible__bu KPSKRELREYVGRDIPTTADQIAAAHELIDRGVTQAVVVSLGADGALLAT
Mvan_4105|M.vanbaalenii_PYR-1 KPSIRELRECVRRELGSEAEQVAAARELIERGGARNVLVSLGAQGALLVT
*.* ***** : : :*:*** :*:: * : *:****.:***:.*
Mb2054c|M.bovis_AF2122/97 RHASHRFSSIPMTAV-SGVGAGDAMVAAITVGLSRGWSLIKSVRLGNAAG
Rv2029c|M.tuberculosis_H37Rv RHASHRFSSIPMTAV-SGVGAGDAMVAAITVGLSRGWSLIKSVRLGNAAG
MMAR_3482|M.marinum_M RRARHRFRAVEMRGG-SGVGAGDAMVAAITVGLARGWPLVKSVRLGIAAG
Mflv_4987|M.gilvum_PYR-GCK PDDSERLSAVPMTSV-SCVGAGDALVAGVAVGLARRWPLGRAVRFGIAAA
MSMEG_3947|M.smegmatis_MC2_155 ARQSQRFKAVPVASG-SGVGAGDAMVAAITVGLSRGWPLPKSVRYGIAAG
TH_1728|M.thermoresistible__bu ADVDQKFEAIDVPVVLSGVGAGDAMVAGITVALSRRWSLSDAVRYGVATG
Mvan_4105|M.vanbaalenii_PYR-1 ADGAQRYPAVEVPPG-SGVGAGDAMVAGVTCGLGRGWGLPKSVRLGIAAG
.: :: : * ******:**.:: .*.* * * :** * *:.
Mb2054c|M.bovis_AF2122/97 AAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVNPEASP
Rv2029c|M.tuberculosis_H37Rv AAMLLTPGTAACNRDDVERFFELAAEPTEVGQDQYVWHPIVNPEASP
MMAR_3482|M.marinum_M AAMLLTPGTQACERADVERLFEHVAEPVEVA----------------
Mflv_4987|M.gilvum_PYR-GCK SAKLQTPGTAAFHRDDVERYFVTQAAHSEA-----------------
MSMEG_3947|M.smegmatis_MC2_155 AAMLLTPGTAVCRRAEVERLFALAAEPEDLTSGW-------------
TH_1728|M.thermoresistible__bu SAMLLTPGTAPCRPEDVERLFAQAAPPVDVTRSPARN----------
Mvan_4105|M.vanbaalenii_PYR-1 AAMLMTPGTASCTRADVERLFDRTPDPVDLTVPAADR----------
:* * **** :*** * . :