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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3824 | - | - | 100% (222) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. thermoresistible (build 8) | TH_1722 | - | 8e-57 | 50.00% (232) | CONSERVED HYPOTHETICAL PROTEIN |
| M. thermoresistible (build 8) | TH_3761 | - | 2e-14 | 32.78% (180) | PUTATIVE methyltransferase type 12 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3725 | - | 2e-54 | 50.42% (236) | hypothetical protein Mb3725 |
| M. gilvum PYR-GCK | Mflv_1324 | - | 6e-50 | 48.47% (229) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3699 | - | 2e-54 | 50.42% (236) | hypothetical protein Rv3699 |
| M. leprae Br4923 | MLBr_00551 | - | 5e-06 | 27.64% (123) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_0961c | - | 2e-52 | 48.46% (227) | hypothetical protein MAB_0961c |
| M. marinum M | MMAR_5210 | - | 7e-52 | 47.03% (236) | hypothetical protein MMAR_5210 |
| M. avium 104 | MAV_0313 | - | 2e-66 | 56.83% (227) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. smegmatis MC2 155 | MSMEG_6235 | - | 2e-57 | 52.19% (228) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. ulcerans Agy99 | MUL_0662 | - | 1e-46 | 53.55% (183) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5471 | - | 5e-49 | 48.70% (230) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3824|M.thermoresistible__bu --------MEWDDMYRRGVP-------PPWSIGAPQPELAALLDAGPAQC
MAV_0313|M.avium_104 ---MTQPDTDWDAAYRQAAP-------PPWSIGRPQPELERLIDE-----
Mb3725|M.bovis_AF2122/97 ---MTDEVMDWDSAYREQGA-FEG--PPPWNIGEPQPELATLIAA-----
Rv3699|M.tuberculosis_H37Rv ---MTDEVMDWDSAYREQGA-FEG--PPPWNIGEPQPELATLIAA-----
MMAR_5210|M.marinum_M ---MTSPVMDWDDAYQQQGA-FEG--PPPWNIGEPQPELAALIAA-----
MSMEG_6235|M.smegmatis_MC2_155 MGVMTSHVLDWDGAYRGDTG-FQG--PPPWNIGEPQPELAALHRA-----
Mflv_1324|M.gilvum_PYR-GCK ----MAEVMDWDSAYRGEGE-FEG--EPPWNIGEPQPELAALWRD-----
Mvan_5471|M.vanbaalenii_PYR-1 -MAHMTDVMDWDSAYRGEGD-FEG--EPPWNIGEPQPELAALWRD-----
MAB_0961c|M.abscessus_ATCC_199 --MTSNELPDWDATYQGKGELFQG--EPPWNIGEPQPELAALIDA-----
MUL_0662|M.ulcerans_Agy99 --MTESLDLQFATAYRGESAEFGAGIRPPWSLGEPQPELATLIEQ-----
MLBr_00551|M.leprae_Br4923 --------MNLYTPIHEDQS-LAAIHRAMWALGDYALMAEEVMAPLGPIL
: : . * :* :
TH_3824|M.thermoresistible__bu PVQGTVRG--EVLDAGCGEAALSLELAARGHTVVGLDCSAAAVAAATATA
MAV_0313|M.avium_104 ---GKFRS--DVLDSGCGHAALSLRLAALGHTVVGLDASATAIAEATAAA
Mb3725|M.bovis_AF2122/97 ---GKVRS--DVLDAGCGYAELSLALAADGYTVVGIDLTPTAVAAATKAA
Rv3699|M.tuberculosis_H37Rv ---GKVRS--DVLDAGCGYAELSLALAADGYTVVGIDLTPTAVAAATKAA
MMAR_5210|M.marinum_M ---GKIHS--DVLDAGCGYAELSLALAAEGYTVVGIDITPTAIAAATKAA
MSMEG_6235|M.smegmatis_MC2_155 ---GRFRS--DVLDAGCGHAELSLALAADGYTVVGMDLSPSAIAAANRAA
Mflv_1324|M.gilvum_PYR-GCK ---GRFRS--EVLDAGCGHAELSLALAADGYTVTGVDISPTAMAAASAAA
Mvan_5471|M.vanbaalenii_PYR-1 ---GKFRS--EVLDAGCGHAELSLALAADGYTVTGVDLSPTAVAAATAAS
MAB_0961c|M.abscessus_ATCC_199 ---GKFHG--TVLDVGCGHAETSLRLAALGHTTVGLDLSPTAIEAARAAA
MUL_0662|M.ulcerans_Agy99 ---GKVHG--EVLDAGCGEAALAMALAGRGHPVVGLDISPTAVELAGREA
MLBr_00551|M.leprae_Br4923 VTATGIRPGMQVLDVAAGSGNISLPAAKTGATIVSTDLTPELLQRSQARA
.: *** ..* . :: * * . .. * :. : : :
TH_3824|M.thermoresistible__bu AERGLTT-ATFAQADLTEFGGY----DGRFSTIIDSGLLHALPVDRRQAY
MAV_0313|M.avium_104 AAQGLTT-ATFARADVTDFADYPPGSEGRFATIVDSGLFHALPPQRRQDY
Mb3725|M.bovis_AF2122/97 EERGLTT-ASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSLPVDSRDRY
Rv3699|M.tuberculosis_H37Rv EERGLTT-ASFVQADITEFAAYPAGSAGRFSTVIDSTLFHSLPVDSRDRY
MMAR_5210|M.marinum_M AERGLGN-TSFMQADITDFNAYPAGSAGRFATVIDSTLFHSLPVSGRDDY
MSMEG_6235|M.smegmatis_MC2_155 QERNLAT-ASFVQGDITSFTGY----DGRFSTVIDSTLFHSLPVEGREGY
Mflv_1324|M.gilvum_PYR-GCK AERGLSEKASFVAADITALSGF----DGRFSTVVDSTLFHSLPVESRAGY
Mvan_5471|M.vanbaalenii_PYR-1 AERGLSERTSFVAADITTLTGF----DGRFATVVDSTLFHSLPVESRDGY
MAB_0961c|M.abscessus_ATCC_199 AERGLTN-ATFEVADITDFSGY----DGRFNTIVDSTLFHSIPVEAREAY
MUL_0662|M.ulcerans_Agy99 ARPGLTN-ASFAVADITDFASYPPESAGRFNTIMDSTLFHSMPVELREGC
MLBr_00551|M.leprae_Br4923 TELGLTL--EYREADAQALPFG----DGEFDVVMSAIGVMFAPDHRR--A
.* : .* : *.* .::.: . * *
TH_3824|M.thermoresistible__bu LRAIHRAAAPNARLFILTFAERPFGDGH----------------------
MAV_0313|M.avium_104 LRSIFRAAAPGAALYILAFAAGALAPAHPDRP------------------
Mb3725|M.bovis_AF2122/97 LSSVHRAAAPGASYYVLVFAKGAFPAELEV--------------------
Rv3699|M.tuberculosis_H37Rv LSSVHRAAAPGASYYVLVFAKGAFPAELEV--------------------
MMAR_5210|M.marinum_M LKSVHRAAAPGASYFVLVFAKGAFPAALET--------------------
MSMEG_6235|M.smegmatis_MC2_155 LQSIHRASAPGARYFVLVFAKGAFPADLEV--------------------
Mflv_1324|M.gilvum_PYR-GCK LESVHRAARPGAGFFVLVFAKGAFPADTEQ--------------------
Mvan_5471|M.vanbaalenii_PYR-1 LQSVHRAAAPGAGYFVLVFAKGAFPAEMEG--------------------
MAB_0961c|M.abscessus_ATCC_199 LQSISRAAAPDASYFVLVFAVGAFPPGIG---------------------
MUL_0662|M.ulcerans_Agy99 QRSIVRAAAPGASYFVLVFDKAALSGDGPI--------------------
MLBr_00551|M.leprae_Br4923 ASELVRVCRPNGTIGVISWTQEGFFGRMLATIRPYRPSLSAALPPAALWG
: *.. *.. :: : :
TH_3824|M.thermoresistible__bu -----------GPDGFTAEELRDTVGVLWTVDEIRPAKLYVNDFTGD---
MAV_0313|M.avium_104 -----------GPQGFTETELREAVSVLWHIDDLRAARVYGNDDSAG---
Mb3725|M.bovis_AF2122/97 -----------KPNEVDEDELRAAVSKYWKIDEIRPAFIHVNPVTIPPQL
Rv3699|M.tuberculosis_H37Rv -----------KPNEVDEDELRAAVSKYWKIDEIRPAFIHVNPVTIPPQL
MMAR_5210|M.marinum_M -----------KPNEVDEDELRAAVGKYWEIDEIRPAFIHANVPVIPPLP
MSMEG_6235|M.smegmatis_MC2_155 -----------KPNEVTEEELRTTVGKYWVVDDIRPAFIHANAVVFP---
Mflv_1324|M.gilvum_PYR-GCK -----------GPNEVSEIELREAVSPYWTIDDIRPALIHTNVPKLP---
Mvan_5471|M.vanbaalenii_PYR-1 -----------GPNEVTELELREAVSRYWIIDDIRPALIDTNVPKLP---
MAB_0961c|M.abscessus_ATCC_199 ------------PNAVTEDELRAAVEPYWAIDELSSAYIHSNIPEVIP--
MUL_0662|M.ulcerans_Agy99 -------------NGVTEEELRDAVSKHWVIDEIRPARIHANLPPEVPG-
MLBr_00551|M.leprae_Br4923 REAYIRGLLDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIEAYT
. . : * : :
TH_3824|M.thermoresistible__bu --LLDGPPTAYERAADGKLM----------FPGFLVSAHKD-
MAV_0313|M.avium_104 --APDSPLAHLERDGEGHFM----------APGFLVSAHKRD
Mb3725|M.bovis_AF2122/97 -AGAPVEFPPYDHDEKGRVK----------FPAYLLTAHKAG
Rv3699|M.tuberculosis_H37Rv -AGAPVEFPPYDHDEKGRVK----------FPAYLLTAHKAG
MMAR_5210|M.marinum_M -AGSPIEFPPHQRDEKGRMK----------FPAYLLTAHKA-
MSMEG_6235|M.smegmatis_MC2_155 ---DAPELPPHGYDDKGRIM----------FPAFLLEAHRD-
Mflv_1324|M.gilvum_PYR-GCK ---GMPPPPLDMLDDRGHLR----------MQAFLLSAHKEP
Mvan_5471|M.vanbaalenii_PYR-1 ---GMPPPPLDMLDDRGRLR----------MQAFLLQAHKES
MAB_0961c|M.abscessus_ATCC_199 --GANFEMPVFHKDEKGRNK----------QPAFLLQAHKR-
MUL_0662|M.ulcerans_Agy99 --CPPSTLATNPRAASPSVRGCSQPIWADGTPHAVYSPANEG
MLBr_00551|M.leprae_Br4923 NIGDNSVLAAELDAQLTELAQKYLTNSTMGWEYLLLTAQKH-
. : . .