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M. thermoresistible (build 8) TH_3820 (-)

annotation: Rieske [2Fe-2S] domain protein
coordinates: 3946362 - 3947699
length: 446

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3820--100% (446)Rieske [2Fe-2S] domain protein
M. thermoresistible (build 8)TH_3362-e-15058.25% (424) PUTATIVE Rieske (2Fe-2S) domain protein
M. thermoresistible (build 8)TH_3877-e-12651.29% (425) PUTATIVE Rieske (2Fe-2S) domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3186c-1e-2934.74% (213) dioxygenase
M. gilvum PYR-GCKMflv_2439-0.079.46% (443) Rieske (2Fe-2S) domain-containing protein
M. tuberculosis H37RvRv3161c-3e-2934.27% (213) dioxygenase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4370c-6e-2031.34% (201) putative large terminal subunit of phenylpropionate dioxygenase
M. marinum MMMAR_4744-0.071.63% (423) dioxygenase
M. avium 104MAV_0905-0.070.07% (421) Rieske (2Fe-2S) domain-containing protein
M. smegmatis MC2 155MSMEG_4840-0.087.02% (447) Rieske (2Fe-2S) domain-containing protein
M. ulcerans Agy99MUL_3820-3e-1427.53% (178) ring-hydroxylating dioxygenase, large terminal subunit
M. vanbaalenii PYR-1Mvan_4213-0.087.13% (443) Rieske (2Fe-2S) domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3186c|M.bovis_AF2122/97           --MLSTDNRAELGDILTDIGDYLDDNPPALSLPP---AAYTS---SELWQ
Rv3161c|M.tuberculosis_H37Rv        --MLSTDNRAELGDILTDIGDYLDDNPPALSLPP---AAYTS---SELWQ
MSMEG_4840|M.smegmatis_MC2_155      -----------MAHFPKPAVGSWTENWPELGTAP---VDYTDSIDPEQWK
Mvan_4213|M.vanbaalenii_PYR-1       -----------MAHFPKPAAGSWTENWPELGTAP---VDYTDSIDPEQWK
TH_3820|M.thermoresistible__bu      -----------VAHFPKPAVGSWTENWPELGTAP---VDYTDSIDPEQWK
Mflv_2439|M.gilvum_PYR-GCK          -----------MAFFKKPDVGSWTENWPELGTAP---VNYEDSIDPEQWK
MMAR_4744|M.marinum_M               -----------MPHFTKPAAGSWTQNYPELGTAP---VDYTDSIDPQYFA
MAV_0905|M.avium_104                -----------MPHFPKPAAGSWTENYPELGTGP---VDYTDSIDPAFFE
MAB_4370c|M.abscessus_ATCC_199      MASLPRPVAVAQGALCRPQALVRDIDVSGLVDSHGGLLDRVIFTDGELYR
MUL_3820|M.ulcerans_Agy99           ------MDRDQLIDLTRRALKLARDKTTDLAPHQH-AVDAREYTSLDRHE
                                                  :          . . *                    

Mb3186c|M.bovis_AF2122/97           LERERIFNRSWMLVAHVDQLAKTGDYVTVSV----AGEPVMVVRDVDGQL
Rv3161c|M.tuberculosis_H37Rv        LERERIFNRSWMLVAHVDQVAKTGDYVTVSV----AGEPVMVVRDVDGQL
MSMEG_4840|M.smegmatis_MC2_155      LEQQAIFRRTWLHVGRVERLPKTGSYFTREMPSVGKGTSIIVVKDKDGAV
Mvan_4213|M.vanbaalenii_PYR-1       LEQQAIFRKLWLHVGRVERLPKAGSYFTREMPSVGAGTSIIVNKDKDGQV
TH_3820|M.thermoresistible__bu      LEQQAIFRRLWLHVGRVERLPKAGSYFTREMPSVGAGTSIIVNRDKDGTI
Mflv_2439|M.gilvum_PYR-GCK          LEQQAIFRKTWLQMGRIELIPKKGSYITRELPSVGPGTSIVIVNDGE-QI
MMAR_4744|M.marinum_M               DEQRAIFRRTWLNVGRIERLPRTGSYFTKELPSTGAGMSVIVVKGKDGVI
MAV_0905|M.avium_104                AEREAIFKKTWLNVGRVNRLPRTGSYFTRELPSAGKGTSVIIVKTKDGSV
MAB_4370c|M.abscessus_ATCC_199      QELRRVFAPSWLFLAHADQFHRPGDFFTTYMG----EDPVIVSMDKNRRI
MUL_3820|M.ulcerans_Agy99           RDRAMVLD-SPQLVGYSSELPGPDTYRTKTIMG----RSILLTRAADRAV
                                     :   ::      :.  . .   . : *  :       .:::    :  :

Mb3186c|M.bovis_AF2122/97           HALSPICRHR---LMLMVEPG---AGRIDTLTCQYHLWRYGLDGRLRGAP
Rv3161c|M.tuberculosis_H37Rv        HALSPICRHR---LMLMVEPG---AGRIDTLTCQYHLWRYGLDGRLRGAP
MSMEG_4840|M.smegmatis_MC2_155      RAFYNMCRHRGNKLVWNDYPGEEVSGTCRQFTCKYHAWRYALNGDLTFIQ
Mvan_4213|M.vanbaalenii_PYR-1       RAFYNLCRHRGNKLVWNDYPGEEVSGSCRQFTCKYHAWRYALDGELTFIQ
TH_3820|M.thermoresistible__bu      RAFYNLCRHRGNKLVWNDYPGEEVSGTCRQFTCKYHGWRYALNGDLTFIQ
Mflv_2439|M.gilvum_PYR-GCK          RAFYNLCRHRGNKLVWNDYPGEETSGTCRQFVCKYHAWRYDLKGDLKFVQ
MMAR_4744|M.marinum_M               RAFHNICRHRGNKLVWNDFPHEETAGTCRQFTCKYHAWRYGLDGELTFIQ
MAV_0905|M.avium_104                KAYHNVCRHRGNKLVWNDFPNEETSGTCRQFTCKYHAWRYSLDGDLTFVQ
MAB_4370c|M.abscessus_ATCC_199      RAFLNSCRHRGARVCRADY------GVTRGFTCTYHGWAYDLEGKLISVP
MUL_3820|M.ulcerans_Agy99           RAFDNVCLHRQSRVATGCG-------TALRFTCPYHGWTYDNGGRLVGLP
                                    :*    * **   :                :.* ** * *   * *    

Mb3186c|M.bovis_AF2122/97           HMAANLD-FNRRECRLPQFA-VATWNGLVWINLDADA-EPIAAHLDLTDD
Rv3161c|M.tuberculosis_H37Rv        HMAANLD-FNRRECRLPQFA-VATWNGLVWINLDADA-EPIAAHLDLTDD
MSMEG_4840|M.smegmatis_MC2_155      QEDEFFD-VDKADYPLKPVR-CEIWEGFIFVNFDDDA-MPLEEYLGEFGQ
Mvan_4213|M.vanbaalenii_PYR-1       QEDEFFD-VDKADYPLKPVR-CEVWEGFIFVNFDDDA-EPLVDYLGDFAK
TH_3820|M.thermoresistible__bu      QEDEFFD-VDKADYGLKPIR-CEVWEGFIFVNFDDDA-EPLEDYLGEFGQ
Mflv_2439|M.gilvum_PYR-GCK          QEQEFFD-LDKQDYPLKPVR-CEVWEGFIFVNFDDDA-VSLEEYLGEFGQ
MMAR_4744|M.marinum_M               QEDEFFD-VDKSQYGLKSVR-CEVWEGFIFINLDPAA-APLSEYLGSMAK
MAV_0905|M.avium_104                QEEEFFD-LDKSNYGLAPVR-CEVWEGFIFINFDDNA-APLTDYLGPLAK
MAB_4370c|M.abscessus_ATCC_199      NEEGYPDSFSTDDWGLVEVPHVDSYHGLIFGTWNPAP-VGLRESLGDMAW
MUL_3820|M.ulcerans_Agy99           GREGFPG-IAVGSDGLTELP-ATEFAGFLWVSLHPAARLDVPAHLGPLAG
                                          . .   .  *  .     : *::: . .  .   :   *.    

Mb3186c|M.bovis_AF2122/97           EFAGYRLGEMVQVESWS----HEWRANWKVAAENGHENYHVLGLHRQTLE
Rv3161c|M.tuberculosis_H37Rv        EFAGYRLGEMVQVESWS----HEWRANWKVAAENGHENYHVLGLHRQTLE
MSMEG_4840|M.smegmatis_MC2_155      GLKGYPFHEMTEVYSYR----AEINSNWKLFIDAFVEFYHAPILHMKQAT
Mvan_4213|M.vanbaalenii_PYR-1       GLEGYPFHEMTEVYSYR----AEINSNWKLFIDAFVEFYHAPILHMKQAT
TH_3820|M.thermoresistible__bu      NLKGYPFHEMTEVYSYR----AEVNANWKLFIDAFTEFYHAPVLHNKQAV
Mflv_2439|M.gilvum_PYR-GCK          GLKGYPFHEMTEHYSYR----AEIKSNWKLFIDAFVEFYHAPILHMKQAE
MMAR_4744|M.marinum_M               GLQGYPFHEMTEVYSYR----AEVGSNWKLFIDAFAEFYHAPVLHQGQYT
MAV_0905|M.avium_104                SIEGYPFGEMTETYSYR----AEVGSNWKLFIDAFVEFYHAPILHQGQYT
MAB_4370c|M.abscessus_ATCC_199      YMDAMLDHDSEGTVVVGGVHKWVLDGNWKLAAEQFATDWYHVNMSHASAL
MUL_3820|M.ulcerans_Agy99           ELQSWGIGRWSPLGEKV----LGSPIDWKLATDTFAENYHFATVHRRTFA
                                     : .                      :**:  :     ::   :      

Mb3186c|M.bovis_AF2122/97           P---------------FVPGGGDLDVRQYSRWALRLRVPFTVPVEAKS--
Rv3161c|M.tuberculosis_H37Rv        P---------------FVPGGGDLDVRQYSRWALRLRVPFTVPVEAKS--
MSMEG_4840|M.smegmatis_MC2_155      PEEAAKLAKIGFEALHYDIKGDHSMISSWGGMSPPKDLNMVKPIERILHS
Mvan_4213|M.vanbaalenii_PYR-1       AEEAAKLAKVGFEALHYDIKDQHSMISSWGGMSPPKDLNMVKPIERILHS
TH_3820|M.thermoresistible__bu      KEEAEKLAKYGYEALHYDIKGPHSMISSWGGMAPPKDPSMVKPIERILNS
Mflv_2439|M.gilvum_PYR-GCK          KEEAEKLAKFGFEALHYDIKGDHSMISSWGGMSPPKDLNMVKPIERILHS
MMAR_4744|M.marinum_M               KEEAAKIMKYGFEALHYELAGPHAMISVWGGQSPPADLKMVKPMDRVLRS
MAV_0905|M.avium_104                KEEAAKIQKFGYEALHYELAGPHSLQSTWGGQAPPPDMSMVKPMDQVLRS
MAB_4370c|M.abscessus_ATCC_199      MVMAPQGKAPKDEIVHRTGRQYVDPNGHGAGFPVHPKNRFDARVVHQWTD
MUL_3820|M.ulcerans_Agy99           T----------------IARSNCTVFDSYG-----PHHRLIFPLNTIL--
                                                                 .         :   :      

Mb3186c|M.bovis_AF2122/97           ----------------LQLNEVQKSNLVV-LWT------FPNSALAIAG-
Rv3161c|M.tuberculosis_H37Rv        ----------------LQLNEVQKSNLVV-LWT------FPNSALAIAG-
MSMEG_4840|M.smegmatis_MC2_155      GLFGPWDRPDIKGILPDELPPAVNPARQP-TWGQDSFEFFPNFTLLLWVP
Mvan_4213|M.vanbaalenii_PYR-1       GLFGPWDRPDIKGILPDELPPAVNPARQP-TWGQDSFEFFPNFTLLLWAP
TH_3820|M.thermoresistible__bu      GLFGPWDRPDIKGIAPDELPPAINPSRQP-FWGQDSFEFFPNFTLLIWAP
Mflv_2439|M.gilvum_PYR-GCK          GLFGPWDRPDIKGILPDELPPAINPGRHK-TWGQDSFEFFPNFTLLFWVP
MMAR_4744|M.marinum_M               GLFGPWDRPAP-ITDLEELPPGINPTKAK-QWGIDSFLFFPNFMLLIWEP
MAV_0905|M.avium_104                GLFGPWDKPE--IIEKLDLPPGVNVKRVP-QWGIDSWLFYPNFMLLIWEP
MAB_4370c|M.abscessus_ATCC_199      YG---------------ALRERLGEARVQGPLTNGHATVFPNLSYLPVNG
MUL_3820|M.ulcerans_Agy99           -----------------ELENVPEGQWDPFHHMVVIYALFPNVVLSVTIA
                                                      *                    :**        

Mb3186c|M.bovis_AF2122/97           ERVVWFGFIPQSIDRVQVLGGVLTTPELAADAAATAQTSQFVMAMINDED
Rv3161c|M.tuberculosis_H37Rv        ERVVWFGFIPQSIDRVQVLGGVLTTPELAADAAATAQTSQFVMAMINDED
MSMEG_4840|M.smegmatis_MC2_155      GWYLTYNYWPTDVDKHIFECNLYFVPPKNTRQRLAQELAAVTFKEYALQD
Mvan_4213|M.vanbaalenii_PYR-1       GWYLTYNYWPTAVDKHIFECNLYFVPPKNTRQRLSQELAAVTFKEYALQD
TH_3820|M.thermoresistible__bu      GWYLTYNYWPTDVTKHIFEASLYFVPPKTTRQRLAQELAAVTFKEYALQD
Mflv_2439|M.gilvum_PYR-GCK          GWYLTYNYWPTGVDTHIFEADLYFVPPKNLRERLSQELAAVTFKEYAFQD
MMAR_4744|M.marinum_M               GWYLTYHYWPTTVDKHIFETTLYFVPPRNARERLAQELAAVTFKEYALQD
MAV_0905|M.avium_104                GWFLTYHYWPTAVDRHIFESTLYFVPPRNARERLAQELAAVTFKEYALQD
MAB_4370c|M.abscessus_ATCC_199      SVRIWHPKGPDKMEVWAWTIVDRSMPEEVRDAQRLYNLRTFGPTGIFEQD
MUL_3820|M.ulcerans_Agy99           NGELFRIYPGDRPGSSITVHQNSTPLDLSDESVATGAQAVFDYAHATVRD
                                       :                                    .       .*

Mb3186c|M.bovis_AF2122/97           RLGLEAVQVGAGSRFAERGHLSSKEWPGMLAFYRNLAMALVGDHP-----
Rv3161c|M.tuberculosis_H37Rv        RLGLEAVQVGAGSRFAERGHLSSKEWPGMLAFYRNLAMALVGDHP-----
MSMEG_4840|M.smegmatis_MC2_155      ANTLEATQTQINTRAVTEFPLCDQEV--LLRHLHHTAHKYVDAYKAELAE
Mvan_4213|M.vanbaalenii_PYR-1       ANTLEATQTQIGTRAVTEFPLCDQEI--LLRHLHHTAHKYVDKYKLEQAA
TH_3820|M.thermoresistible__bu      ANTLEATQTQIGTRAVTEFPLCDQEV--LLRHLHHTAHQYVDKYKEELAQ
Mflv_2439|M.gilvum_PYR-GCK          ANTLEATQTQIGTRAVLDFPLCDQEV--LLRHLHHTAHKYVDRYKAELEA
MMAR_4744|M.marinum_M               SNTLEATQTMIGTGVVKDFPLCDQEI--LLRHLHKMTGDYVKEYR-----
MAV_0905|M.avium_104                ANTLEATQTMIGTRAVKEFLLCDQEV--LIRHLHKTTGDYVKEYQ-----
MAB_4370c|M.abscessus_ATCC_199      DGENWSEVQSISRGFVTNSVALNYQMGLDSEREDGRHPGLTSELYSDAAG
MUL_3820|M.ulcerans_Agy99           EDYRLAETLQTNLESGARQRLVFGRNEPGLQHRHITWAQALETPG-----
                                         :     .            .                         

Mb3186c|M.bovis_AF2122/97           -----------GAS----------
Rv3161c|M.tuberculosis_H37Rv        -----------GAS----------
MSMEG_4840|M.smegmatis_MC2_155      KTQ---KAESNGSAVTSEKDAAHV
Mvan_4213|M.vanbaalenii_PYR-1       K------AATNGSASKTEKEGANV
TH_3820|M.thermoresistible__bu      K-----AQQTNGSKKEGARSTAHV
Mflv_2439|M.gilvum_PYR-GCK          KSNGSSNGATTSSTTATQKDEVNA
MMAR_4744|M.marinum_M               ---------NNGHAK---------
MAV_0905|M.avium_104                ---------NNGHVAAR-------
MAB_4370c|M.abscessus_ATCC_199      RSFYARWRDLMNTKAWHEEHV---
MUL_3820|M.ulcerans_Agy99           ------------------------